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Erschienen in: Current Anesthesiology Reports 1/2015

01.03.2015 | Perioperative Delirium (JM Leung, Section Editor)

Blood Transfusion and Postoperative Delirium

verfasst von: Elizabeth L. Whitlock, Matthias Behrends

Erschienen in: Current Anesthesiology Reports | Ausgabe 1/2015

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Abstract

Postoperative delirium (POD) is a common complication of surgery associated with significant morbidity and mortality. Transfusion of packed red blood cells has been reproducibly associated with POD in many retrospective and prospective cohort studies. We review the biological evidence for a potential causal pathway between transfusion and delirium via oxidative stress and neuroinflammation, and summarize the clinical literature on delirium and transfusion to date.
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Metadaten
Titel
Blood Transfusion and Postoperative Delirium
verfasst von
Elizabeth L. Whitlock
Matthias Behrends
Publikationsdatum
01.03.2015
Verlag
Springer US
Erschienen in
Current Anesthesiology Reports / Ausgabe 1/2015
Elektronische ISSN: 2167-6275
DOI
https://doi.org/10.1007/s40140-014-0085-2

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