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28.02.2017 | Editorial

The WHO recommendation for 80% perioperative oxygen is poorly justified

verfasst von: Prof. Dr. T. Volk, J. Peters, D. I. Sessler

Erschienen in: Die Anaesthesiologie | Ausgabe 4/2017

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Excerpt

Members of the WHO Guidelines Development Group recently attempted to provide worldwide “evidence-based recommendations” for the prevention of surgical site infections (SSI) by stating:

Adult patients undergoing general anaesthesia with endotracheal intubation for surgical procedures should receive 80% fraction of inspired oxygen intraoperatively and, if feasible, in the immediate postoperative period for 2–6 h [1].

…

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Anthony T, Murray BW, Sum-Ping JT et al (2011) Evaluating an evidence-based bundle for preventing surgical site infection: a randomized trial. Arch Surg 146:263–269CrossRefPubMed

Belda FJ, Aguilera L, de la García Asunción J et al (2005) Supplemental perioperative oxygen and the risk of surgical wound infection: a randomized controlled trial. JAMA 294(16):2035–2042CrossRefPubMed

Bickel A, Gurevits M, Vamos R et al (2011) Perioperative hyperoxygenation and wound site infection following surgery for acute appendicitis: a randomized, prospective, controlled trial. Arch Surg 146(4):464–470CrossRefPubMed

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Duggal N, Poddatoori V, Noroozkhani S et al (2013) Perioperative oxygen supplementation and surgical site infection after cesarean delivery: a randomized trial. Obstet Gynecol 122:79–84CrossRefPubMed

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10.

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Hopf HW, Hunt TK, West JM et al (1997) Wound tissue oxygen tension predicts the risk of wound infection in surgical patients. Arch Surg 132:997–1005CrossRefPubMed

12.

Kurz A, Fleischmann E, Sessler DI et al (2015) Effects of supplemental oxygen and dexamethasone on surgical site infection: a factorial randomized trial. Br J Anaesth 115:434–443CrossRefPubMed

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Mayzler O, Weksler N, Domchik S et al (2005) Does supplemental perioperative oxygen administration reduce the incidence of wound infection in elective colorectal surgery? Minerva Anestesiol 71(1–2):21–25PubMed

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Meyhoff CS, Wetterslev J, Jorgensen LN et al (2009) Effect of high perioperative oxygen fraction on surgical site infection and pulmonary complications after abdominal surgery: the PROXI randomized clinical trial. JAMA 302(14):1543–1550CrossRefPubMed

16.

Meyhoff CS, Jorgensen LN, Wetterslev J et al (2012) Increased long-term mortality after a high perioperative inspiratory oxygen fraction during abdominal surgery: follow-up of a randomized clinical trial. Anesth Analg 115:849–854CrossRefPubMed

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Meyhoff CS, Jorgensen LN, Rasmussen LS et al (2015) High oxygen concentration to prevent surgical site infection after rectal cancer surgery. Am J Surg 209(4):771CrossRefPubMed

18.

Nikolaou NI, Arntz HR, Bellou A et al (2015) European Resuscitation Council Guidelines for Resuscitation 2015 Section 8. Initial management of acute coronary syndromes. Resuscitation 95:264–277CrossRefPubMed

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Pryor KO, Fahey TJ 3rd, Lien CA et al (2004) Surgical site infection and the routine use of perioperative hyperoxia in a general surgical population: a randomized controlled trial. JAMA 291(1):79–87CrossRefPubMed

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Schietroma M, Cecilia EM, Carlei F, al at (2013) Prevention of anastomotic leakage after total gastrectomy with perioperative supplemental oxygen administration: a prospective randomized, double-blind, controlled, single-center trial. Ann Surg Oncol 20(5):1584–1590CrossRefPubMed

23.

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26.

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29.

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30.

Williams NL, Glover MM, Crisp C et al (2013) Randomized controlled trial of the effect of 30 % versus 80 % fraction of inspired oxygen on cesarean delivery surgical site infection. Am J Perinatol 30:781–786CrossRefPubMed

Titel: The WHO recommendation for 80% perioperative oxygen is poorly justified
verfasst von: Prof. Dr. T. Volk
J. Peters
D. I. Sessler
Publikationsdatum: 28.02.2017
Verlag: Springer Medizin
Erschienen in: Die Anaesthesiologie / Ausgabe 4/2017
Print ISSN: 2731-6858
Elektronische ISSN: 2731-6866
DOI: https://doi.org/10.1007/s00101-017-0286-4

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