nach oben

Erschienen in:

01.04.2014 | Year in Review 2013

Year in review in Intensive Care Medicine 2013: III. Sepsis, infections, respiratory diseases, pediatrics

verfasst von: Jean-Francois Timsit, Giuseppe Citerio, Jan Bakker, Matteo Bassetti, Dominique Benoit, Maurizio Cecconi, J. Randall Curtis, Glenn Hernandez, Margaret Herridge, Samir Jaber, Michael Joannidis, Laurent Papazian, Mark Peters, Pierre Singer, Martin Smith, Marcio Soares, Antoni Torres, Antoine Vieillard-Baron, Elie Azoulay

Erschienen in: Intensive Care Medicine | Ausgabe 4/2014

Einloggen, um Zugang zu erhalten

Excerpt

Dobutamine has been widely advocated to improve (inadequate) cardiac output in septic shock. However, on the basis of the double-blind, crossover, randomized study from Hernandez et al. [1], the microcirculatory and regional effects, despite improvement of the macrocirculation, seem to be limited. Indeed despite an increase in cardiac output and heart rate, with dobutamine, they found no significant impact on lactate level and sublingual vessel perfused density. This is in contrast to some other studies. The question now is were the results of these earlier studies wrong or is the current baseline resuscitation of critically ill patients so different from these earlier days that the state of the vasculature of our patients is now different when compared to those earlier days? …

Hernandez G, Bruhn A, Luengo C et al (2013) Effects of dobutamine on systemic, regional and microcirculatory perfusion parameters in septic shock: a randomized, placebo-controlled, double-blind, crossover study. Intensive Care Med 39:1435–1443. doi:10.1007/s00134-013-2982-0 PubMedCrossRef

Vassiliou AG, Maniatis NA, Kotanidou A et al (2013) Endothelial protein C receptor polymorphisms and risk of severe sepsis in critically ill patients. Intensive Care Med 39:1752–1759. doi:10.1007/s00134-013-3018-5 PubMedCrossRef

Delabranche X, Boisrame-Helms J, Asfar P et al (2013) Microparticles are new biomarkers of septic shock-induced disseminated intravascular coagulopathy. Intensive Care Med 39:1695–1703. doi:10.1007/s00134-013-2993-x PubMedCrossRef

Levi M, van der Poll T (2013) Endothelial injury in sepsis. Intensive Care Med 39:1839–1842. doi:10.1007/s00134-013-3054-1 PubMedCrossRef

Yamakawa K, Ogura H, Fujimi S et al (2013) Recombinant human soluble thrombomodulin in sepsis-induced disseminated intravascular coagulation: a multicenter propensity score analysis. Intensive Care Med 39:644–652. doi:10.1007/s00134-013-2822-2 PubMedCentralPubMedCrossRef

Pranskunas A, Koopmans M, Koetsier PM et al (2013) Microcirculatory blood flow as a tool to select ICU patients eligible for fluid therapy. Intensive Care Med 39:612–619. doi:10.1007/s00134-012-2793-8 PubMedCentralPubMedCrossRef

Dünser MW, Takala J, Brunauer A, Bakker J (2013) Re-thinking resuscitation: leaving blood pressure cosmetics behind and moving forward to permissive hypotension and a tissue perfusion-based approach. Crit Care 17:326. doi:10.1186/cc12727 PubMedCrossRef

Kurniati NF, Jongman RM, vom Hagen F et al (2013) The flow dependency of Tie2 expression in endotoxemia. Intensive Care Med 39:1262–1271. doi:10.1007/s00134-013-2899-7 PubMedCrossRef

Huang DT, Angus DC, Barnato A et al (2013) Harmonizing international trials of early goal-directed resuscitation for severe sepsis and septic shock: methodology of ProCESS, ARISE, and ProMISe. Intensive Care Med 39:1760–1775. doi:10.1007/s00134-013-3024-7 PubMedCrossRef

10.

Guignant C, Venet F, Planel S et al (2013) Increased MerTK expression in circulating innate immune cells of patients with septic shock. Intensive Care Med 39:1556–1564. doi:10.1007/s00134-013-3006-9 PubMedCrossRef

11.

Kim YA, Ha E-J, Jhang WK, Park SJ (2013) Early blood lactate area as a prognostic marker in pediatric septic shock. Intensive Care Med 39:1818–1823. doi:10.1007/s00134-013-2959-z PubMedCrossRef

12.

Suberviola B, Castellanos-Ortega A, Ruiz Ruiz A et al (2013) Hospital mortality prognostication in sepsis using the new biomarkers suPAR and proADM in a single determination on ICU admission. Intensive Care Med 39:1945–1952. doi:10.1007/s00134-013-3056-z PubMedCrossRef

13.

Brinkman S, Abu-Hanna A, de Jonge E, de Keizer NF (2013) Prediction of long-term mortality in ICU patients: model validation and assessing the effect of using in-hospital versus long-term mortality on benchmarking. Intensive Care Med 39:1925–1931. doi:10.1007/s00134-013-3042-5 PubMedCrossRef

14.

Shimamoto Y, Fukuda T, Tanaka K et al (2013) Systemic inflammatory response syndrome criteria and vancomycin dose requirement in patients with sepsis. Intensive Care Med 39:1247–1252. doi:10.1007/s00134-013-2909-9 PubMedCrossRef

15.

Udy AA, Roberts JA, Lipman J (2013) Clinical implications of antibiotic pharmacokinetic principles in the critically ill. Intensive Care Med 39:2070–2082. doi:10.1007/s00134-013-3088-4 PubMedCrossRef

16.

Harron K, Wade A, Muller-Pebody B et al (2013) Risk-adjusted monitoring of blood-stream infection in paediatric intensive care: a data linkage study. Intensive Care Med 39:1080–1087. doi:10.1007/s00134-013-2841-z PubMedCrossRef

17.

Mermel LA, Allon M, Bouza E et al (2009) Clinical practice guidelines for the diagnosis and management of intravascular catheter-related infection: 2009 update by the Infectious Diseases Society of America. Clin Infect Dis 49:1–45. doi:10.1086/599376 PubMedCrossRef

18.

Gowardman JR, Jeffries P, Lassig-Smith M et al (2013) A comparative assessment of two conservative methods for the diagnosis of catheter-related infection in critically ill patients. Intensive Care Med 39:109–116. doi:10.1007/s00134-012-2689-7 PubMedCrossRef

19.

Airapetian N, Maizel J, Langelle F et al (2013) Ultrasound-guided central venous cannulation is superior to quick-look ultrasound and landmark methods among inexperienced operators: a prospective randomized study. Intensive Care Med 39:1938–1944. doi:10.1007/s00134-013-3072-z PubMedCrossRef

20.

Bedel J, Vallee F, Mari A et al (2013) Guidewire localization by transthoracic echocardiography during central venous catheter insertion: a periprocedural method to evaluate catheter placement. Intensive Care Med 39:1932–1937. doi:10.1007/s00134-013-3097-3 PubMedCrossRef

21.

European Antimicrobial Resistance Surveillance Network (EARS-Net) (2013) Antimicrobial resistance surveillance in Europe 2012. Surveillance report. http://www.ecdc.europa.eu/en/activities/surveillance/EARS-Net. Accessed 29 Jan 2014

22.

Tabah A, Koulenti D, Laupland K et al (2012) Characteristics and determinants of outcome of hospital-acquired bloodstream infections in intensive care units: the EUROBACT International Cohort Study. Intensive Care Med 38:1930–1945. doi:10.1007/s00134-012-2695-9 PubMedCrossRef

23.

Routsi C, Pratikaki M, Platsouka E et al (2013) Risk factors for carbapenem-resistant gram-negative bacteremia in intensive care unit patients. Intensive Care Med 39:1253–1261. doi:10.1007/s00134-013-2914-z PubMedCrossRef

24.

Oostdijk EAN, Smits L, de Smet AMGA et al (2013) Colistin resistance in gram-negative bacteria during prophylactic topical colistin use in intensive care units. Intensive Care Med 39:653–660. doi:10.1007/s00134-012-2761-3 PubMedCrossRef

25.

Halaby T, Al Naiemi N, Kluytmans J et al (2013) Emergence of colistin resistance in Enterobacteriaceae after the introduction of selective digestive tract decontamination in an intensive care unit. Antimicrob Agents Chemother 57:3224–3229. doi:10.1128/AAC.02634-12 PubMedCentralPubMedCrossRef

26.

Schultsz C, Bootsma MCJ, Loan HT et al (2013) Effects of infection control measures on acquisition of five antimicrobial drug-resistant microorganisms in a tetanus intensive care unit in Vietnam. Intensive Care Med 39:661–671. doi:10.1007/s00134-012-2771-1 PubMedCentralPubMedCrossRef

27.

Derde LPG, Cooper BS, Goossens H et al (2014) Interventions to reduce colonisation and transmission of antimicrobial-resistant bacteria in intensive care units: an interrupted time series study and cluster randomised trial. Lancet Infect Dis 14:31–39. doi:10.1016/S1473-3099(13)70295-0 PubMedCentralPubMedCrossRef

28.

Zahar JR, Garrouste-Orgeas M, Vesin A et al (2013) Impact of contact isolation for multidrug-resistant organisms on the occurrence of medical errors and adverse events. Intensive Care Med 39:2153–2160. doi:10.1007/s00134-013-3071-0 PubMedCrossRef

29.

Vogiatzi L, Ilia S, Sideri G et al (2013) Invasive candidiasis in pediatric intensive care in Greece: a nationwide study. Intensive Care Med 39:2188–2195. doi:10.1007/s00134-013-3057-y PubMedCrossRef

30.

Bassetti M, Marchetti M, Chakrabarti A et al (2013) A research agenda on the management of intra-abdominal candidiasis: results from a consensus of multinational experts. Intensive Care Med 39:2092–2106. doi:10.1007/s00134-013-3109-3 PubMedCrossRef

31.

Di Pasquale M, Esperatti M, Crisafulli E et al (2013) Impact of chronic liver disease in intensive care unit acquired pneumonia: a prospective study. Intensive Care Med 39:1776–1784. doi:10.1007/s00134-013-3025-6 PubMedCrossRef

32.

Martin-Loeches I, Deja M, Koulenti D et al (2013) Potentially resistant microorganisms in intubated patients with hospital-acquired pneumonia: the interaction of ecology, shock and risk factors. Intensive Care Med 39:672–681. doi:10.1007/s00134-012-2808-5 PubMedCrossRef

33.

Tumbarello M, De Pascale G, Trecarichi EM et al (2013) Clinical outcomes of Pseudomonas aeruginosa pneumonia in intensive care unit patients. Intensive Care Med 39:682–692. doi:10.1007/s00134-013-2828-9 PubMedCrossRef

34.

Rello J, Borgatta B, Lisboa T (2013) Risk factors for Pseudomonas aeruginosa pneumonia in the early twenty-first century. Intensive Care Med 39:2204–2206. doi:10.1007/s00134-013-3046-1 PubMedCrossRef

35.

Brusselaers N, Labeau S, Vogelaers D, Blot S (2013) Value of lower respiratory tract surveillance cultures to predict bacterial pathogens in ventilator-associated pneumonia: systematic review and diagnostic test accuracy meta-analysis. Intensive Care Med 39:365–375. doi:10.1007/s00134-012-2759-x PubMedCrossRef

36.

Bouza E, Perez Granda MJ, Hortal J et al (2013) Pre-emptive broad-spectrum treatment for ventilator-associated pneumonia in high-risk patients. Intensive Care Med 39:1547–1555. doi:10.1007/s00134-013-2997-6 PubMedCrossRef

37.

Villar J, Kacmarek RM (2013) What is new in refractory hypoxemia? Intensive Care Med 39:1207–1210. doi:10.1007/s00134-013-2905-0 PubMedCrossRef

38.

Ehrmann S, Roche-Campo F, Papa GFS et al (2013) Aerosol therapy during mechanical ventilation: an international survey. Intensive Care Med 39:1048–1056. doi:10.1007/s00134-013-2872-5 PubMedCrossRef

39.

Seymour CW, Yende S, Scott MJ et al (2013) Metabolomics in pneumonia and sepsis: an analysis of the GenIMS cohort study. Intensive Care Med 39:1423–1434. doi:10.1007/s00134-013-2935-7 PubMedCrossRef

40.

Martin-Loeches I, Bermejo-Martin JF, Valles J et al (2013) Macrolide-based regimens in absence of bacterial co-infection in critically ill H1N1 patients with primary viral pneumonia. Intensive Care Med 39:693–702. doi:10.1007/s00134-013-2829-8 PubMedCrossRef

41.

Cracco C, Fartoukh M, Prodanovic H et al (2013) Safety of performing fiberoptic bronchoscopy in critically ill hypoxemic patients with acute respiratory failure. Intensive Care Med 39:45–52. doi:10.1007/s00134-012-2687-9 PubMedCentralPubMedCrossRef

42.

Jong A, Clavieras N, Conseil M et al (2013) Implementation of a combo videolaryngoscope for intubation in critically ill patients: a before–after comparative study. Intensive Care Med 39:2144–2152. doi:10.1007/s00134-013-3099-1 PubMedCrossRef

43.

De Gast-Bakker DH, de Wilde RBP, Hazekamp MG et al (2013) Safety and effects of two red blood cell transfusion strategies in pediatric cardiac surgery patients: a randomized controlled trial. Intensive Care Med 39:2011–2019. doi:10.1007/s00134-013-3085-7 PubMedCrossRef

44.

Du Pont-Thibodeau G, Lacroix J (2013) Do cardiac children need more red blood cell transfusions than other critically ill children? Intensive Care Med 39:2050–2052. doi:10.1007/s00134-013-3082-x PubMedCrossRef

45.

Tritschler T, Frey B (2013) Is the number of drugs independently associated with mortality? Intensive Care Med 39:2060–2062. doi:10.1007/s00134-013-3065-y PubMedCrossRef

46.

Vet NJ, Ista E, de Wildt SN et al (2013) Optimal sedation in pediatric intensive care patients: a systematic review. Intensive Care Med 39:1524–1534. doi:10.1007/s00134-013-2971-3 PubMedCrossRef

47.

Van de Voorde P, Van Lander A, Colpaert K et al (2013) An urgent plea: give the use of prolonged propofol infusion a second thought. Intensive Care Med 39:2058–2059. doi:10.1007/s00134-013-3058-x PubMedCrossRef

48.

Garcia Guerra G, Joffe AR, Senthilselvan A et al (2013) Incidence of milrinone blood levels outside the therapeutic range and their relevance in children after cardiac surgery for congenital heart disease. Intensive Care Med 39:951–957. doi:10.1007/s00134-013-2858-3 PubMedCrossRef

49.

Smulders CA, van Gestel JPJ, Bos AP (2013) Are central line bundles and ventilator bundles effective in critically ill neonates and children? Intensive Care Med 39:1352–1358. doi:10.1007/s00134-013-2927-7 PubMedCrossRef

50.

Ramnarayan P, Patel K, Pappachan J et al (2013) Characteristics and outcome of children admitted to adult intensive care units in England, Wales and Northern Ireland (1996–2011). Intensive Care Med 39:2020–2027. doi:10.1007/s00134-013-3010-0 PubMedCrossRef

51.

Polito A, Barrett CS, Wypij D et al (2013) Neurologic complications in neonates supported with extracorporeal membrane oxygenation. An analysis of ELSO registry data. Intensive Care Med 39:1594–1601. doi:10.1007/s00134-013-2985-x PubMedCrossRef

52.

Madderom MJ, Reuser JJCM, Utens EMWJ et al (2013) Neurodevelopmental, educational and behavioral outcome at 8 years after neonatal ECMO: a nationwide multicenter study. Intensive Care Med 39:1584–1593. doi:10.1007/s00134-013-2973-1 PubMedCrossRef

53.

Brown KL, MacLaren G, Marino BS (2013) Looking beyond survival rates: neurological outcomes after extracorporeal life support. Intensive Care Med 39:1870–1872. doi:10.1007/s00134-013-3050-5 PubMedCrossRef

54.

Visser IHE, Hazelzet JA, Albers MJIJ et al (2013) Mortality prediction models for pediatric intensive care: comparison of overall and subgroup specific performance. Intensive Care Med 39:942–950. doi:10.1007/s00134-013-2857-4 PubMedCrossRef

55.

Polito A, Piga S, Cogo PE et al (2013) Increased morbidity and mortality in very preterm/VLBW infants with congenital heart disease. Intensive Care Med 39:1104–1112. doi:10.1007/s00134-013-2887-y PubMedCrossRef

56.

Lopez-Herce J, del Castillo J, Matamoros M et al (2013) Factors associated with mortality in pediatric in-hospital cardiac arrest: a prospective multicenter multinational observational study. Intensive Care Med 39:309–318. doi:10.1007/s00134-012-2709-7 PubMedCrossRef

57.

Oualha M, Gatterre P, Boddaert N et al (2013) Early diffusion-weighted magnetic resonance imaging in children after cardiac arrest may provide valuable prognostic information on clinical outcome. Intensive Care Med 39:1306–1312. doi:10.1007/s00134-013-2930-z PubMedCrossRef

58.

Floh AA, La Rotta G, Wermelt JZ et al (2013) Validation of a new method based on ultrasound velocity dilution to measure cardiac output in paediatric patients. Intensive Care Med 39:926–933. doi:10.1007/s00134-013-2848-5 PubMedCrossRef

59.

De Luca D, Piastra M, Chidini G et al (2013) The use of the Berlin definition for acute respiratory distress syndrome during infancy and early childhood: multicenter evaluation and expert consensus. Intensive Care Med 39:2083–2091. doi:10.1007/s00134-013-3110-x PubMedCrossRef

60.

Van Berkel S, Binkhorst M, van Heijst AFJ et al (2013) Adapted ECMO criteria for newborns with persistent pulmonary hypertension after inhaled nitric oxide and/or high-frequency oscillatory ventilation. Intensive Care Med 39:1113–1120. doi:10.1007/s00134-013-2907-y PubMedCrossRef

61.

Dellaca RL, Veneroni C, Vendettuoli V et al (2013) Relationship between respiratory impedance and positive end-expiratory pressure in mechanically ventilated neonates. Intensive Care Med 39:511–519. doi:10.1007/s00134-012-2795-6 PubMedCrossRef

62.

Milesi C, Baleine J, Matecki S et al (2013) Is treatment with a high flow nasal cannula effective in acute viral bronchiolitis? A physiologic study. Intensive Care Med 39:1088–1094. doi:10.1007/s00134-013-2879-y PubMedCrossRef

63.

Essouri S, Laurent M, Chevret L et al (2014) Improved clinical and economic outcomes in severe bronchiolitis with pre-emptive nCPAP ventilatory strategy. Intensive Care Med 40:84–91. doi:10.1007/s00134-013-3129-z PubMedCrossRef

64.

Lee JH, Rehder KJ, Williford L et al (2013) Use of high flow nasal cannula in critically ill infants, children, and adults: a critical review of the literature. Intensive Care Med 39:247–257. doi:10.1007/s00134-012-2743-5 PubMedCrossRef

65.

Mayordomo-Colunga J, Pons M, Lopez Y et al (2013) Predicting non-invasive ventilation failure in children from the SpO(2)/FiO(2) (SF) ratio. Intensive Care Med 39:1095–1103. doi:10.1007/s00134-013-2880-5 PubMedCrossRef

66.

Caldarelli V, Borel JC, Khirani S et al (2013) Polygraphic respiratory events during sleep with noninvasive ventilation in children: description, prevalence, and clinical consequences. Intensive Care Med 39:739–746. doi:10.1007/s00134-012-2806-7 PubMedCrossRef

67.

Jouvet PA, Payen V, Gauvin F et al (2013) Weaning children from mechanical ventilation with a computer-driven protocol: a pilot trial. Intensive Care Med 39:919–925. doi:10.1007/s00134-013-2837-8 PubMedCrossRef

68.

Egelund TA, Wassil SK, Edwards EM et al (2013) High-dose magnesium sulfate infusion protocol for status asthmaticus: a safety and pharmacokinetics cohort study. Intensive Care Med 39:117–122. doi:10.1007/s00134-012-2734-6 PubMedCrossRef

69.

Deep A, Goonasekera CDA, Wang Y, Brierley J (2013) Evolution of haemodynamics and outcome of fluid-refractory septic shock in children. Intensive Care Med 39:1602–1609. doi:10.1007/s00134-013-3003-z PubMedCrossRef

70.

Paize F, Makwana N, Baines PB et al (2013) Diastolic dysfunction and N-terminal pro-brain natriuretic peptide in children with meningococcal sepsis. Intensive Care Med 39:1501–1502. doi:10.1007/s00134-013-2948-2 PubMedCrossRef

71.

Xu X-J, Tang Y-M, Liao C et al (2013) Inflammatory cytokine measurement quickly discriminates gram-negative from gram-positive bacteremia in pediatric hematology/oncology patients with septic shock. Intensive Care Med 39:319–326. doi:10.1007/s00134-012-2752-4 PubMedCrossRef

72.

Schlapbach LJ, Graf R, Woerner A et al (2013) Pancreatic stone protein as a novel marker for neonatal sepsis. Intensive Care Med 39:754–763. doi:10.1007/s00134-012-2798-3 PubMedCrossRef

73.

Spaeder MC (2013) Severe adenoviral respiratory infection in children. Intensive Care Med 39:1157–1158. doi:10.1007/s00134-013-2893-0 PubMedCrossRef

Titel: Year in review in Intensive Care Medicine 2013: III. Sepsis, infections, respiratory diseases, pediatrics
verfasst von: Jean-Francois Timsit
Giuseppe Citerio
Jan Bakker
Matteo Bassetti
Dominique Benoit
Maurizio Cecconi
J. Randall Curtis
Glenn Hernandez
Margaret Herridge
Samir Jaber
Michael Joannidis
Laurent Papazian
Mark Peters
Pierre Singer
Martin Smith
Marcio Soares
Antoni Torres
Antoine Vieillard-Baron
Elie Azoulay
Publikationsdatum: 01.04.2014
Verlag: Springer Berlin Heidelberg
Erschienen in: Intensive Care Medicine / Ausgabe 4/2014
Print ISSN: 0342-4642
Elektronische ISSN: 1432-1238
DOI: https://doi.org/10.1007/s00134-014-3235-6

Update AINS

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.

hier abonnieren

Springer Medizin

Year in review in Intensive Care Medicine 2013: III. Sepsis, infections, respiratory diseases, pediatrics

Excerpt

Neu im Fachgebiet AINS

Bei schweren Reaktionen auf Insektenstiche empfiehlt sich eine spezifische Immuntherapie

Hinter dieser Appendizitis steckte ein Erreger

Ärztliche Empathie hilft gegen Rückenschmerzen

Mehr Schaden als Nutzen durch präoperatives Aussetzen von GLP-1-Agonisten?

Update AINS

Springer Medizin

Excerpt

Bitte loggen Sie sich ein, um Zugang zu diesem Inhalt zu erhalten

Weitere Artikel der Ausgabe 4/2014

Multiple embolisms resulted from a huge fishbone piercing the left atrium

A pulsatile chest wall mass: pseudoaneurysm of the ascending aorta

The importance of word choice in the care of critically ill patients and their families

What’s new in extracorporeal membrane oxygenation for cardiac failure and cardiac arrest in adults?

Loop diuretics are an independent risk factor for acute kidney injury in children on extracorporeal membrane oxygenation with pre-emptive continuous hemofiltration

Cardiopulmonary resuscitation among mechanically ventilated patients

Neu im Fachgebiet AINS

Bei schweren Reaktionen auf Insektenstiche empfiehlt sich eine spezifische Immuntherapie

Hinter dieser Appendizitis steckte ein Erreger

Ärztliche Empathie hilft gegen Rückenschmerzen

Mehr Schaden als Nutzen durch präoperatives Aussetzen von GLP-1-Agonisten?

Update AINS