Skip to main content
Erschienen in: Rechtsmedizin 5/2015

01.10.2015 | Originalien

The potential of infrared pupillography in routine police traffic checks

verfasst von: Dr. F.C. Monticelli, W. Hitzl, F. Priemer, U. Preiss, S.N. Kunz, T. Keller

Erschienen in: Rechtsmedizin | Ausgabe 5/2015

Einloggen, um Zugang zu erhalten

Abstract

Background

In order to evaluate driving abilities of each traffic participant, standardized and objective measurement methods are still needed. The applicability and value of infrared pupillography as an objective measurement method to indicate possible influence of central nervous acting substances has been demonstrated in former publications.

Objectives

To tie in with first results of the study, the aim was to extend the statistical analysis to further parameters of the pupillary light reflex (PLR) in order to demonstrate their relevance and to substantiate the value of infrared pupillography for possible implementation in the framework of routine police traffic checks.

Materials and methods

We exposed the iris of healthy test subjects (n = 41), as well as of persons who were under the influence of drugs and/or medication (n = 105), to different light stimuli using infrared technology. After measuring and splitting the PLR into single parameters a statistical analysis was performed.

Results

The pupillary light reflex was significantly alterated when the examined person was under the influence of central nervous acting substances. In concordance with former reported results, the majority of the parameters approved the high value of the PLR as a reliable indicator of previous consumption of drugs and/or central nervous acting medication. The most appropriate parameters of the pupillary light reflex for identification of drivers under the influence of central nervous acting substances are indicated in the study.

Conclusions

Infrared pupillography represents an objective method of measuring the pupil function to indicate a possible influence by central nervous acting substances. As we were able to prove the applicability of the device used in the present study during routine police traffic controls, we suggest that infrared pupillography should become a regular method in scheduled traffic controls in the future, preferably in cooperation with forensic medical centers.
Literatur
1.
Zurück zum Zitat Alexandridis E (1971) Pupillographie. Anwendungsmöglichkeiten als objektive Untersuchungsmethode der Netzhautsinnesfunktion. Hüthig, Heidelberg Alexandridis E (1971) Pupillographie. Anwendungsmöglichkeiten als objektive Untersuchungsmethode der Netzhautsinnesfunktion. Hüthig, Heidelberg
2.
Zurück zum Zitat Bergamin O, Kardon RH (2003) Latency of the pupil light reflex: sample rate, stimulus intensity, and variation in normal subjects. Invest Ophthalmol Vis Sci 44:1546–1554CrossRefPubMed Bergamin O, Kardon RH (2003) Latency of the pupil light reflex: sample rate, stimulus intensity, and variation in normal subjects. Invest Ophthalmol Vis Sci 44:1546–1554CrossRefPubMed
4.
Zurück zum Zitat Hill T, Lewicki P (2006) Statistics methods and applications. StatSoft, Tulsa Hill T, Lewicki P (2006) Statistics methods and applications. StatSoft, Tulsa
5.
Zurück zum Zitat Lindauer A, Siepmann T, Oertel R, Jung A, Ziemssen T, Jaehde U et al (2008) Pharmacokinetic/pharmacodynamic modelling of venlafaxine: pupillary light reflex as a test system for noradrenergic effects. Clin Pharmacokinet 47:721–731CrossRefPubMed Lindauer A, Siepmann T, Oertel R, Jung A, Ziemssen T, Jaehde U et al (2008) Pharmacokinetic/pharmacodynamic modelling of venlafaxine: pupillary light reflex as a test system for noradrenergic effects. Clin Pharmacokinet 47:721–731CrossRefPubMed
6.
Zurück zum Zitat Loewenfeld IE (1999) The Pupil. Anatomy, Physiology, and Clinical Applications. Butterworth Heinemann, Boston Loewenfeld IE (1999) The Pupil. Anatomy, Physiology, and Clinical Applications. Butterworth Heinemann, Boston
7.
Zurück zum Zitat Monticelli F, Priemer F, Hitzl W, Keller T (2010) Pupil function as an indicator for being under the influence of central nervous acting substances from a traffic-medicine perspective. Med Sci Law 50:75–83CrossRefPubMed Monticelli F, Priemer F, Hitzl W, Keller T (2010) Pupil function as an indicator for being under the influence of central nervous acting substances from a traffic-medicine perspective. Med Sci Law 50:75–83CrossRefPubMed
8.
Zurück zum Zitat Müller-Jensen A, Hagenah R (1976) Untersuchungen zur Variabilität des phasischen Pupillenlichtreflexes. J Neurol 212:123–132CrossRefPubMed Müller-Jensen A, Hagenah R (1976) Untersuchungen zur Variabilität des phasischen Pupillenlichtreflexes. J Neurol 212:123–132CrossRefPubMed
9.
Zurück zum Zitat Murillo R, Crucilla C, Schmittner J, Hotchkiss E, Pickworth WB (2004) Pupillometry in the detection of concomitant drug use in opioid-maintained patients. Methods Find Exp Clin Pharmacol 26:271–275PubMed Murillo R, Crucilla C, Schmittner J, Hotchkiss E, Pickworth WB (2004) Pupillometry in the detection of concomitant drug use in opioid-maintained patients. Methods Find Exp Clin Pharmacol 26:271–275PubMed
10.
Zurück zum Zitat Ostrin LA, Glasser A (2004) The effects of phenylephrine on pupil diameter and accommodation in rhesus monkeys. Invest Ophthalmol Vis Sci 45:215–221PubMedCentralCrossRefPubMed Ostrin LA, Glasser A (2004) The effects of phenylephrine on pupil diameter and accommodation in rhesus monkeys. Invest Ophthalmol Vis Sci 45:215–221PubMedCentralCrossRefPubMed
11.
Zurück zum Zitat Priemer F, Sachs H (2000) The compact integrated pupillograph CIP (AMTech)—its value on detection of psychophysical disorder caused by drugs, Abstract 219: 15th International Conference on Alcohol, Drugs, and Traffic Safety, Stockholm Priemer F, Sachs H (2000) The compact integrated pupillograph CIP (AMTech)—its value on detection of psychophysical disorder caused by drugs, Abstract 219: 15th International Conference on Alcohol, Drugs, and Traffic Safety, Stockholm
12.
Zurück zum Zitat Priemer F, Büchler J, Schwab M, Spitzer M, Kovar KA (2003) Pupillenfunktion unter akuter MDE-Wirkung. BASt M 152. In: Rainer Mattern, Dieter Krause. German Society of Traffic Medicine, 32nd Annual Meeting: 143–146 Priemer F, Büchler J, Schwab M, Spitzer M, Kovar KA (2003) Pupillenfunktion unter akuter MDE-Wirkung. BASt M 152. In: Rainer Mattern, Dieter Krause. German Society of Traffic Medicine, 32nd Annual Meeting: 143–146
13.
Zurück zum Zitat Pürstl G (2011) Strassenverkehrsordnung Austrian Road Traffic regulations—With explanatory notes in the light of its legislative history and an overview of the law, 13th ed. Manz, Vienna Pürstl G (2011) Strassenverkehrsordnung Austrian Road Traffic regulations—With explanatory notes in the light of its legislative history and an overview of the law, 13th ed. Manz, Vienna
14.
Zurück zum Zitat Verster JC, Veldhuijzen DS, Volkerts ER (2006) Effects of an opioid (Oxycodone/Paracetamol) and an NSAID (Bromfenac) on driving ability, memory functioning, psychomotor performance, pupil size, and mood. Clin J Pain 22:499–504CrossRefPubMed Verster JC, Veldhuijzen DS, Volkerts ER (2006) Effects of an opioid (Oxycodone/Paracetamol) and an NSAID (Bromfenac) on driving ability, memory functioning, psychomotor performance, pupil size, and mood. Clin J Pain 22:499–504CrossRefPubMed
15.
Zurück zum Zitat Volpe NJ, Plotkin ES, Maguire MG, Hariprasad R, Galetta SL (2000) Portable pupillography of the swinging flashlight test to detect afferent pupillary defects. Ophthalmology 107:1913–1922CrossRefPubMed Volpe NJ, Plotkin ES, Maguire MG, Hariprasad R, Galetta SL (2000) Portable pupillography of the swinging flashlight test to detect afferent pupillary defects. Ophthalmology 107:1913–1922CrossRefPubMed
16.
Zurück zum Zitat Wilhelm H (1991) Pupillenreaktionen—Pupillenstörungen. Kohlhammer, Stuttgart Wilhelm H (1991) Pupillenreaktionen—Pupillenstörungen. Kohlhammer, Stuttgart
18.
Zurück zum Zitat Wilhelm H, Wilhelm B (2003) Clinical applications of pupillography. J Neuroophthalmol 23(1):42–49CrossRefPubMed Wilhelm H, Wilhelm B (2003) Clinical applications of pupillography. J Neuroophthalmol 23(1):42–49CrossRefPubMed
Metadaten
Titel
The potential of infrared pupillography in routine police traffic checks
verfasst von
Dr. F.C. Monticelli
W. Hitzl
F. Priemer
U. Preiss
S.N. Kunz
T. Keller
Publikationsdatum
01.10.2015
Verlag
Springer Berlin Heidelberg
Erschienen in
Rechtsmedizin / Ausgabe 5/2015
Print ISSN: 0937-9819
Elektronische ISSN: 1434-5196
DOI
https://doi.org/10.1007/s00194-015-0023-8

Weitere Artikel der Ausgabe 5/2015

Rechtsmedizin 5/2015 Zur Ausgabe

Der besondere Fall im Bild

Forellenphänomen

Rechtsprechung

Rechtsreport

Neu im Fachgebiet Rechtsmedizin

Molekularpathologische Untersuchungen im Wandel der Zeit

Open Access Biomarker Leitthema

Um auch an kleinen Gewebeproben zuverlässige und reproduzierbare Ergebnisse zu gewährleisten ist eine strenge Qualitätskontrolle in jedem Schritt des Arbeitsablaufs erforderlich. Eine nicht ordnungsgemäße Prüfung oder Behandlung des …

Vergleichende Pathologie in der onkologischen Forschung

Pathologie Leitthema

Die vergleichende experimentelle Pathologie („comparative experimental pathology“) ist ein Fachbereich an der Schnittstelle von Human- und Veterinärmedizin. Sie widmet sich der vergleichenden Erforschung von Gemeinsamkeiten und Unterschieden von …

Gastrointestinale Stromatumoren

Open Access GIST CME-Artikel

Gastrointestinale Stromatumoren (GIST) stellen seit über 20 Jahren ein Paradigma für die zielgerichtete Therapie mit Tyrosinkinaseinhibitoren dar. Eine elementare Voraussetzung für eine mögliche neoadjuvante oder adjuvante Behandlung bei …

Personalisierte Medizin in der Onkologie

Aufgrund des erheblichen technologischen Fortschritts in der molekularen und genetischen Diagnostik sowie zunehmender Erkenntnisse über die molekulare Pathogenese von Krankheiten hat in den letzten zwei Jahrzehnten ein grundlegender …