Erschienen in:
01.10.2010 | Letter
Withholding selective decontamination of the digestive tract from critically ill patients must now surely be ethically questionable given the vast evidence base
verfasst von:
Durk F Zandstra, Andy J Petros, Nia Taylor, Luciano Silvestri, Miguel A de la Cal, Hendrick KF van Saene
Erschienen in:
Critical Care
|
Ausgabe 5/2010
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Excerpt
Shibli and colleagues recently commented [
1] on the Dutch randomised controlled trial in which selective digestive decontamination (SDD) and selective oro-pharyngeal decontamination (SOD) were associated with significantly lower odds of death as compared with standard care, with odds ratios of 0.83 (
P = 0.02) and 0.86 (
P = 0.045), respectively [
2]. We disagree with the authors' conclusion that, because there were similar mortality reductions, SOD may be preferred as this avoids routinely exposing patients to intravenous antibiotics and involves less resistance. …