Ausgabe 10/2023
Inhalt (21 Artikel)
Clinical trials of neoadjuvant immune checkpoint inhibitors for early-stage operable colon and rectal cancer
Torhild Veen, Arezo Kanani, Dordi Lea, Kjetil Søreide
Using patient-derived tumor organoids from common epithelial cancers to analyze personalized T-cell responses to neoantigens
Anup Y. Parikh, Robert Masi, Billel Gasmi, Ken-ichi Hanada, Maria Parkhurst, Jared Gartner, Sivasish Sindiri, Todd Prickett, Paul Robbins, Nikolaos Zacharakis, Mike Beshiri, Kathleen Kelly, Steven A. Rosenberg, James C. Yang
Revealing the impact of CD70 expression on the manufacture and functions of CAR-70 T-cells based on single-cell transcriptomics
Jiali Cheng, Yuyan Zhao, Hui Hu, Ling Tang, Yuhao Zeng, Xinyue Deng, Shengnan Ding, An-Yuan Guo, Qing Li, Xiaojian Zhu
Prognostic survival biomarkers of tumor-fused dendritic cell vaccine therapy in patients with newly diagnosed glioblastoma
Jun Takei, Yuko Kamata, Toshihide Tanaka, Nei Fukasawa, Kazutaka Gomisawa, Mari Satake, Ryosuke Mori, Yohei Yamamoto, Tomoya Suzuki, Ayaka Oda, Mutsunori Murahashi, Takahiro Fukuda, Masayuki Shimoda, Yuichi Murayama, Yasuharu Akasaki
CD24 is a novel target of chimeric antigen receptor T cells for the treatment of triple negative breast cancer
Peiwei Yang, Fan Yu, Zheng Yao, Xu Ding, Hanmei Xu, Juan Zhang
DLGAP5 promotes gallbladder cancer migration and tumor-associated macrophage M2 polarization by activating cAMP
Jie Huang, Mengyao Zheng, Yan Li, Dingwei Xu, Daguang Tian
Immune-related adverse events and disease outcomes after the third dose of SARS-CoV-2 mRNA-BNT162b2 vaccine in cancer patients receiving immune checkpoint inhibitors
Fabrizio Nelli, Diana Giannarelli, Agnese Fabbri, Antonella Virtuoso, Julio Rodrigo Giron Berrios, Eleonora Marrucci, Cristina Fiore, Marta Schirripa, Carlo Signorelli, Mario Giovanni Chilelli, Francesca Primi, Valentina Panichi, Giuseppe Topini, Maria Assunta Silvestri, Enzo Maria Ruggeri
SIGLEC10+ macrophages drive gastric cancer progression by suppressing CD8+ T cell function
Yixian Guo, Shouyu Ke, Feng Xie, Jieqiong Chen, Xu Liu, Zeyu Wang, Danhua Xu, Yanying Shen, Gang Zhao, Wenyi Zhao, Hong Lu
Chimeric antigen receptor macrophages activated through TLR4 or IFN-γ receptors suppress breast cancer growth by targeting VEGFR2
Zhaojun Duan, Zhen Li, Ziyuan Wang, Chong Chen, Yunping Luo
Identification of an antigen-presenting cells/T/NK cells-related gene signature to predict prognosis and CTSL to predict immunotherapeutic response for lung adenocarcinoma: an integrated analysis of bulk and single-cell RNA sequencing
Liling Huang, Ning Lou, Tongji Xie, Le Tang, Xiaohong Han, Yuankai Shi
Piper nigrum extract suppresses tumor growth and enhances the antitumor immune response in murine models of breast cancer and melanoma
Paola Lasso, Laura Rojas, Cindy Arévalo, Claudia Urueña, Natalia Murillo, Paula Nossa, Tito Sandoval, Luis Carlos Chitiva, Alfonso Barreto, Geison M. Costa, Susana Fiorentino
Circadian pattern subtyping unveiling distinct immune landscapes in breast cancer patients for better immunotherapy
Siqi Xiong, Wenqiang Zhu, Liqing Wu, Tianmin Zhou, Wu Wang, Ouyang Zhang, Xiaoliang Xiong, Zhuoqi Liu, Daya Luo
Oncolytic attenuated measles virus encoding NY-ESO-1 induces HLA I and II presentation of this tumor antigen by melanoma and dendritic cells
Marion Grard, Mohamed Idjellidaine, Atousa Arbabian, Camille Chatelain, Laurine Berland, Chantal Combredet, Soizic Dutoit, Sophie Deshayes, Virginie Dehame, Nathalie Labarrière, Delphine Fradin, Nicolas Boisgerault, Christophe Blanquart, Frédéric Tangy, Jean-François Fonteneau
Good manufacturing practice production of CD34+ progenitor-derived NK cells for adoptive immunotherapy in acute myeloid leukemia
P. K. J. D. de Jonge, P. M. M. van Hauten, L. D. Janssen, A. L. de Goede, M. M. Berrien-Elliott, J. M. R. van der Meer, C. M. Mousset, M. W. H. Roeven, M. Foster, N. Blijlevens, W. Hobo, T. A. Fehniger, J. H. Jansen, N. P. M. Schaap, H. Dolstra
Previous radiotherapy improves treatment responses and causes a trend toward longer time to progression among patients with immune checkpoint inhibitor-related adverse events
Anna Jokimäki, Henna Hietala, Jasmiini Lemma, Hanna Karhapää, Anna Rintala, Jari-Pekka Kaikkonen, Kaisa Sunela, Eva Boman, Arja Jukkola, Satu Tiainen, Jan Seppälä, Aino Rönkä, Heikki Hakkarainen, Aarno Kärnä, Sanna Iivanainen, Jussi Koivunen, Päivi Auvinen, Micaela Hernberg, Milla Kuusisto, Tuomas Selander, Outi Kuittinen
Blockade of tumor-derived colony-stimulating factor 1 (CSF1) promotes an immune-permissive tumor microenvironment
Maria del Mar Maldonado, Jeffrey Schlom, Duane H. Hamilton
Melanoma-derived soluble mediators modulate neutrophil biological properties and the release of neutrophil extracellular traps
Luca Modestino, Leonardo Cristinziano, Marialuisa Trocchia, Annagioia Ventrici, Mariaelena Capone, Gabriele Madonna, Stefania Loffredo, Anne Lise Ferrara, Marilena Romanelli, Ester Simeone, Gilda Varricchi, Francesca Wanda Rossi, Amato de Paulis, Gianni Marone, Paolo Antonio Ascierto, Maria Rosaria Galdiero
Successful ex vivo expansion of tumor infiltrating lymphocytes with systemic chemotherapy prior to surgical resection
Julien Balzeau, Anindita Ravindran, Xin Wang, Jinal Maisuria, Anna Lucchesi, Hui Yao, Satoko Matsueda
Immune checkpoint inhibitor treatment of brain metastasis associated with a less invasive growth pattern, higher T-cell infiltration and raised tumor ADC on diffusion weighted MRI
Rasheed Zakaria, Michael D. Jenkinson, Mark Radon, Kumar Das, Harish Poptani, Nitika Rathi, Philip S. Rudland
Correction to: Anti-mesothelin CAR-T immunotherapy in patients with ovarian cancer
Jiannan Chen, Jianhua Hu, Lili Gu, Feng Ji, Fan Zhang, Miaomiao Zhang, Jun Li, Zhengliang Chen, Longwei Jiang, Yan Zhang, Ruifang Shi, Lihua Ma, Shaochang Jia, Ying Zhang, Qi Zhang, Junqing Liang, Shunyu Yao, Zhigang Hu, Zhigang Guo