Ausgabe 6/2016
Inhalt (12 Artikel)
Strategies to genetically engineer T cells for cancer immunotherapy
Timothy T. Spear, Kaoru Nagato, Michael I. Nishimura
Tumour infiltrating lymphocytes correlate with improved survival in patients with oesophageal adenocarcinoma
Fergus Noble, Toby Mellows, Leo H. McCormick Matthews, Adrian C. Bateman, Scott Harris, Timothy J. Underwood, James P. Byrne, Ian S. Bailey, Donna M. Sharland, Jamie J. Kelly, John N. Primrose, Surinder S. Sahota, Andrew R. Bateman, Gareth J. Thomas, Christian H. Ottensmeier
2′–5′ Oligoadenylate synthetase-like 1 (OASL1) deficiency in mice promotes an effective anti-tumor immune response by enhancing the production of type I interferons
Chan Kyu Sim, Yeon Sook Cho, Byung Soo Kim, In-Jeoung Baek, Young-Joon Kim, Myeong Sup Lee
Endostatin inhibits the growth and migration of 4T1 mouse breast cancer cells by skewing macrophage polarity toward the M1 phenotype
Hua Guo, Yanan Liu, Junlian Gu, Yue Wang, Lianqin Liu, Ping Zhang, Yang Li
Differential immunomodulatory activity of tumor cell death induced by cancer therapeutic toll-like receptor ligands
Johanna C. Klein, Clarissa A. Wild, Stephan Lang, Sven Brandau
Immunogenicity and efficacy of the novel cancer vaccine based on simian adenovirus and MVA vectors alone and in combination with PD-1 mAb in a mouse model of prostate cancer
Federica Cappuccini, Stephen Stribbling, Emily Pollock, Adrian V. S. Hill, Irina Redchenko
Myeloid-derived suppressor cells correlate with patient outcomes in hepatic arterial infusion chemotherapy for hepatocellular carcinoma
Eishiro Mizukoshi, Tatsuya Yamashita, Kuniaki Arai, Takeshi Terashima, Masaaki Kitahara, Hidetoshi Nakagawa, Noriho Iida, Kazumi Fushimi, Shuichi Kaneko
Disease progression in recurrent glioblastoma patients treated with the VEGFR inhibitor axitinib is associated with increased regulatory T cell numbers and T cell exhaustion
Stephanie Du Four, Sarah K. Maenhout, Daphné Benteyn, Brenda De Keersmaecker, Johnny Duerinck, Kris Thielemans, Bart Neyns, Joeri L. Aerts
Neutrophil elastase enhances antigen presentation by upregulating human leukocyte antigen class I expression on tumor cells
Akhil Chawla, Gheath Alatrash, Anne V. Philips, Na Qiao, Pariya Sukhumalchandra, Celine Kerros, Iulia Diaconu, Victor Gall, Samantha Neal, Haley L. Peters, Karen Clise-Dwyer, Jeffrey J. Molldrem, Elizabeth A. Mittendorf
Concomitant targeting of programmed death-1 (PD-1) and CD137 improves the efficacy of radiotherapy in a mouse model of human BRAFV600-mutant melanoma
Paula Kroon, Jules Gadiot, Marlies Peeters, Alessia Gasparini, Marcel A. Deken, Hideo Yagita, Marcel Verheij, Jannie Borst, Christian U. Blank, Inge Verbrugge
A case report of insulin-dependent diabetes as immune-related toxicity of pembrolizumab: presentation, management and outcome
Elizabeth Hansen, Deepak Sahasrabudhe, Lynn Sievert
Determining predictive factors for immune checkpoint inhibitor toxicity: Response to Letter to the Editors “A case report of insulin-dependent diabetes as immune-related toxicity of pembrolizumab: presentation, management and outcome”
Lavinia Spain, James Larkin, Juan Martin-Liberal