Ausgabe 1/2017
Inhalt (265 Artikel)
Adjuvant effects of a sequence-engineered mRNA vaccine: translational profiling demonstrates similar human and murine innate response
Darin K. Edwards, Edith Jasny, Heesik Yoon, Nigel Horscroft, Brian Schanen, Tanya Geter, Mariola Fotin-Mleczek, Benjamin Petsch, Vaughan Wittman
Mobilization of hematopoietic stem cells with the novel CXCR4 antagonist POL6326 (balixafortide) in healthy volunteers—results of a dose escalation trial
Darja Karpova, Susanne Bräuninger, Eliza Wiercinska, Ariane Krämer, Belinda Stock, Jochen Graff, Hans Martin, Achim Wach, Christophe Escot, Garry Douglas, Barbara Romagnoli, Eric Chevalier, Klaus Dembowski, Leon Hooftman, Halvard Bonig
Two differentially structured collagen scaffolds for potential urinary bladder augmentation: proof of concept study in a Göttingen minipig model
Dorothea Leonhäuser, Katja Stollenwerk, Volker Seifarth, Isabella M. Zraik, Michael Vogt, Pramod K. Srinivasan, Rene H. Tolba, Joachim O. Grosse
Endothelial microparticles are increased in congenital heart diseases and contribute to endothelial dysfunction
Ze-Bang Lin, Hong-Bo Ci, Yan Li, Tian-Pu Cheng, Dong-Hong Liu, Yan-Sheng Wang, Jun Xu, Hao-Xiang Yuan, Hua-Ming Li, Jing Chen, Li Zhou, Zhi-Ping Wang, Xi Zhang, Zhi-Jun Ou, Jing-Song Ou
Placental mitochondrial DNA and CYP1A1 gene methylation as molecular signatures for tobacco smoke exposure in pregnant women and the relevance for birth weight
Bram G. Janssen, Wilfried Gyselaers, Hyang-Min Byun, Harry A. Roels, Ann Cuypers, Andrea A. Baccarelli, Tim S. Nawrot
Advances in rare cell isolation: an optimization and evaluation study
Stefan Schreier, Piamsiri Sawaisorn, Rachanee Udomsangpetch, Wannapong Triampo
Prediction of anti-inflammatory proteins/peptides: an insilico approach
Sudheer Gupta, Ashok K. Sharma, Vibhuti Shastri, Midhun K. Madhu, Vineet K. Sharma
B cell repertoires in HLA-sensitized kidney transplant candidates undergoing desensitization therapy
John F. Beausang, H. Christina Fan, Rene Sit, Maria U. Hutchins, Kshama Jirage, Rachael Curtis, Edward Hutchins, Stephen R. Quake, Julie M. Yabu
Study of the microRNA expression profile of foreskin derived mesenchymal stromal cells following inflammation priming
Hussein Fayyad-Kazan, Mohammad Fayyad-Kazan, Bassam Badran, Dominique Bron, Laurence Lagneaux, Mehdi Najar
Inhibitory effects of serum from sepsis patients on epithelial cell migration in vitro: a case control study
Henna Jaurila, Vesa Koivukangas, Marjo Koskela, Fiia Gäddnäs, Sirpa Salo, Johanna Korvala, Maija Risteli, Toni Karhu, Karl-Heinz Herzig, Tuula Salo, Tero I. Ala-Kokko
Effects of the intradiscal implantation of stromal vascular fraction plus platelet rich plasma in patients with degenerative disc disease
Kristin Comella, Robert Silbert, Michelle Parlo
Antibiotics-induced depletion of mice microbiota induces changes in host serotonin biosynthesis and intestinal motility
Xiaolong Ge, Chao Ding, Wei Zhao, Lizhi Xu, Hongliang Tian, Jianfeng Gong, Minsheng Zhu, Jieshou Li, Ning Li
Lymph node pooling: a feasible and efficient method of lymph node molecular staging in colorectal carcinoma
Natalia Rakislova, Carla Montironi, Iban Aldecoa, Eva Fernandez, Josep Antoni Bombi, Mireya Jimeno, Francesc Balaguer, Maria Pellise, Antoni Castells, Miriam Cuatrecasas
Realising stratified psychiatry using multidimensional signatures and trajectories
Dan W. Joyce, Angie A. Kehagia, Derek K. Tracy, Jessica Proctor, Sukhwinder S. Shergill
Neuroregenerative potential of intravenous G-CSF and autologous peripheral blood stem cells in children with cerebral palsy: a randomized, double-blind, cross-over study
Wee-Jin Rah, Young-Ho Lee, Jin-Hwa Moon, Hyun-Ju Jun, Hye-Ryeong Kang, Hani Koh, Hye Jung Eom, Ji Young Lee, Young Jun Lee, Ji Young Kim, Yun-Young Choi, Kyeongil Park, Mi Jung Kim, Seung-Hyun Kim
Genetic instability and increased mutational load: which diagnostic tool best direct patients with cancer to immunotherapy?
Giuseppe Palmieri, Maria Colombino, Antonio Cossu, Antonio Marchetti, Gerardo Botti, Paolo A. Ascierto
Near infrared fluorescent imaging of brain tumor with IR780 dye incorporated phospholipid nanoparticles
Shihong Li, Jennifer Johnson, Anderson Peck, Qian Xie
Inhibitory effect of a novel peptide, H-RN, on keratitis induced by LPS or poly(I:C) in vitro and in vivo via suppressing NF-κB and MAPK activation
Shaopin Zhu, Xun Xu, Lili Wang, Li Su, Qing Gu, Fang Wei, Kun Liu
A phase II trial of stereotactic body radiotherapy with concurrent anti-PD1 treatment in metastatic melanoma: evaluation of clinical and immunologic response
Katrien De Wolf, Vibeke Kruse, Nora Sundahl, Mireille van Gele, Ines Chevolet, Reinhart Speeckaert, Lieve Brochez, Piet Ost
Towards standardization of next-generation sequencing of FFPE samples for clinical oncology: intrinsic obstacles and possible solutions
Maxim Ivanov, Konstantin Laktionov, Valery Breder, Polina Chernenko, Ekaterina Novikova, Ekaterina Telysheva, Sergey Musienko, Ancha Baranova, Vladislav Mileyko
Microwave ablation combined with OK-432 induces Th1-type response and specific antitumor immunity in a murine model of breast cancer
Li Li, Wei Wang, Hong Pan, Ge Ma, Xinyi Shi, Hui Xie, Xiaoan Liu, Qiang Ding, Wenbin Zhou, Shui Wang
Novel neuro-audiological findings and further evidence for TWNK involvement in Perrault syndrome
Monika Ołdak, Dominika Oziębło, Agnieszka Pollak, Iwona Stępniak, Michal Lazniewski, Urszula Lechowicz, Krzysztof Kochanek, Mariusz Furmanek, Grażyna Tacikowska, Dariusz Plewczynski, Tomasz Wolak, Rafał Płoski, Henryk Skarżyński
Individualized analysis reveals CpG sites with methylation aberrations in almost all lung adenocarcinoma tissues
Haidan Yan, Qingzhou Guan, Jun He, Yunqing Lin, Juan Zhang, Hongdong Li, Huaping Liu, Yunyan Gu, Zheng Guo, Fei He
Optimized creation of glioblastoma patient derived xenografts for use in preclinical studies
Doreen William, Christina Susanne Mullins, Björn Schneider, Andrea Orthmann, Nora Lamp, Mathias Krohn, Annika Hoffmann, Carl-Friedrich Classen, Michael Linnebacher
HIF-1α inhibitor echinomycin reduces acute graft-versus-host disease and preserves graft-versus-leukemia effect
Yushi Yao, Lei Wang, Jihao Zhou, Xinyou Zhang
Pyruvate kinase M2 and the mitochondrial ATPase Inhibitory Factor 1 provide novel biomarkers of dermatomyositis: a metabolic link to oncogenesis
Fulvio Santacatterina, María Sánchez-Aragó, Marc Catalán-García, Glòria Garrabou, Cristina Nuñez de Arenas, Josep M. Grau, Francesc Cardellach, José M. Cuezva
Association of osteopontin with specific prognostic factors and survival in adjuvant breast cancer trials of the Hellenic Cooperative Oncology Group
Amanda Psyrri, Konstantine T. Kalogeras, Ralph M. Wirtz, George Kouvatseas, Georgia Karayannopoulou, Anna Goussia, Flora Zagouri, Elke Veltrup, Eleni Timotheadou, Helen Gogas, Angelos Koutras, Georgios Lazaridis, Christos Christodoulou, George Pentheroudakis, Panagiota Economopoulou, Apostolos Laskarakis, Petroula Arapantoni-Dadioti, Anna Batistatou, Maria Sotiropoulou, Gerasimos Aravantinos, Pavlos Papakostas, Paris Kosmidis, Dimitrios Pectasides, George Fountzilas
The active metabolite of leflunomide, A77 1726, attenuates inflammatory arthritis in mice with spontaneous arthritis via induction of heme oxygenase-1
Su-Jin Moon, Eun-Kyung Kim, Joo Yeon Jhun, Hee Jin Lee, Weon Sun Lee, Sang-Hi Park, Mi-La Cho, Jun-Ki Min
Tacrolimus in the prevention of adverse pregnancy outcomes and diabetes-associated embryopathies in obese and diabetic mice
Ahmad J. H. Albaghdadi, Melanie A. Hewitt, Samantha M. Putos, Michael Wells, Terence R. S. Ozolinš, Frederick W. K. Kan
A novel cytoprotective peptide protects mesenchymal stem cells against mitochondrial dysfunction and apoptosis induced by starvation via Nrf2/Sirt3/FoxO3a pathway
Shuo Wang, Chao Zhang, Sidikejiang Niyazi, Long Zheng, Jiawei Li, Weitao Zhang, Ming Xu, Ruiming Rong, Cheng Yang, Tongyu Zhu
Bone Morphogenetic Proteins and myostatin pathways: key mediator of human sarcopenia
Manuel Scimeca, Eleonora Piccirilli, Francesca Mastrangeli, Cecilia Rao, Maurizio Feola, Augusto Orlandi, Elena Gasbarra, Elena Bonanno, Umberto Tarantino
Exendin-4 in combination with adipose-derived stem cells promotes angiogenesis and improves diabetic wound healing
Eunhui Seo, Jae Soo Lim, Jin-Bum Jun, Woohyuk Choi, In-Sun Hong, Hee-Sook Jun
Immune modulation of some autoimmune diseases: the critical role of macrophages and neutrophils in the innate and adaptive immunity
Kely Campos Navegantes, Rafaelli de Souza Gomes, Priscilla Aparecida Tártari Pereira, Paula Giselle Czaikoski, Carolina Heitmann Mares Azevedo, Marta Chagas Monteiro
Distinct patterns and prognostic values of tumor-infiltrating macrophages in hepatocellular carcinoma and gastric cancer
Jin-Qing Li, Xing-Juan Yu, Yong-Chun Wang, Li-Yun Huang, Chao-Qun Liu, Limin Zheng, Yu-jing Fang, Jing Xu
TCD4pos lymphocytosis in rheumatoid and psoriatic arthritis patients following TNFα blocking agents
Andrea Picchianti Diamanti, Bruno Laganà, Maria Christina Cox, Emanuela Pilozzi, Rachele Amodeo, Maurizio Bove, Milica Markovic, Roberta Di Rosa, Simonetta Salemi, Maria Laura Sorgi, Maria Manuela Rosado, Raffaele D’Amelio
Melanoma antigen-specific effector T cell cytokine secretion patterns in patients treated with ipilimumab
Yana G. Najjar, Fei Ding, Yan Lin, Robert VanderWeele, Lisa H. Butterfield, Ahmad A. Tarhini
Generation of donor-specific Tr1 cells to be used after kidney transplantation and definition of the timing of their in vivo infusion in the presence of immunosuppression
Bechara Mfarrej, Eleonora Tresoldi, Angela Stabilini, Alessia Paganelli, Rossana Caldara, Antonio Secchi, Manuela Battaglia
Identification of miRNA-mRNA crosstalk in CD4+ T cells during HIV-1 infection by integrating transcriptome analyses
Qibin Liao, Jin Wang, Zenglin Pei, Jianqing Xu, Xiaoyan Zhang
IRE1α-XBP1 pathway promotes melanoma progression by regulating IL-6/STAT3 signaling
Cheng Chen, Xuejun Zhang
Assessment of plasma chitotriosidase activity, CCL18/PARC concentration and NP-C suspicion index in the diagnosis of Niemann-Pick disease type C: a prospective observational study
Isabel De Castro-Orós, Pilar Irún, Jorge Javier Cebolla, Victor Rodriguez-Sureda, Miguel Mallén, María Jesús Pueyo, Pilar Mozas, Carmen Dominguez, Miguel Pocoví
Circulating tumor cells capture disease evolution in advanced prostate cancer
Justin Lack, Marc Gillard, Maggie Cam, Gladell P. Paner, David J. VanderWeele
Erratum to: Walking performance is positively correlated to calf muscle fiber size in peripheral artery disease subjects, but fibers show aberrant mitophagy: an observational study
Sarah H. White, Mary M. McDermott, Robert L. Sufit, Kate Kosmac, Alex W. Bugg, Marta Gonzalez-Freire, Luigi Ferrucci, Lu Tian, Lihui Zhao, Ying Gao, Melina R. Kibbe, Michael H. Criqui, Christiaan Leeuwenburgh, Charlotte A. Peterson
COX-2 expression positively correlates with PD-L1 expression in human melanoma cells
Gerardo Botti, Federica Fratangelo, Margherita Cerrone, Giuseppina Liguori, Monica Cantile, Anna Maria Anniciello, Stefania Scala, Crescenzo D’Alterio, Chiara Trimarco, Angela Ianaro, Giuseppe Cirino, Corrado Caracò, Maria Colombino, Giuseppe Palmieri, Stefano Pepe, Paolo Antonio Ascierto, Francesco Sabbatino, Giosuè Scognamiglio
Imatinib increases oxygen delivery in extracellular matrix-rich but not in matrix-poor experimental carcinoma
Mikhail Burmakin, Tijs van Wieringen, P. Olof Olsson, Linda Stuhr, Aive Åhgren, Carl-Henrik Heldin, Rolf K. Reed, Kristofer Rubin, Carina Hellberg
Comparative analysis of curative effect of bone marrow mesenchymal stem cell and bone marrow mononuclear cell transplantation for spastic cerebral palsy
Xuebin Liu, Xiaojun Fu, Guanghui Dai, Xiaodong Wang, Zan Zhang, Hongbin Cheng, Pei Zheng, Yihua An
Therapeutic strategies for cell-based neovascularization in critical limb ischemia
Makoto Samura, Tohru Hosoyama, Yuriko Takeuchi, Koji Ueno, Noriyasu Morikage, Kimikazu Hamano
A rabbit model for experimental alveolar cleft grafting
Mohammad Kamal, Lars Andersson, Rene Tolba, Alexander Bartella, Felix Gremse, Frank Hölzle, Peter Kessler, Bernd Lethaus
Heterogeneity of Toll-like receptor 9 signaling in B cell malignancies and its potential therapeutic application
Ling Bai, Wei Chen, Jingtao Chen, Wei Li, Lei Zhou, Chao Niu, Wei Han, Jiuwei Cui
Luteolin suppresses gastric cancer progression by reversing epithelial-mesenchymal transition via suppression of the Notch signaling pathway
Ming-de Zang, Lei Hu, Zhi-yuan Fan, He-xiao Wang, Zheng-lun Zhu, Shu Cao, Xiong-yan Wu, Jian-fang Li, Li-ping Su, Chen Li, Zheng-gang Zhu, Min Yan, Bing-ya Liu
Stability of pro- and anti-inflammatory immune biomarkers for human cohort studies
C. Graham, R. Chooniedass, W. P. Stefura, L. Lotoski, P. Lopez, A. D. Befus, A. B. Becker, K. T. HayGlass
Endothelial and smooth muscle cells derived from human cardiac explants demonstrate angiogenic potential and suitable for design of cell-containing vascular grafts
I. S. Zakharova, M. K. Zhiven’, Sh. B. Saaya, A. I. Shevchenko, A. M. Smirnova, A. Strunov, A. A. Karpenko, E. A. Pokushalov, L. N. Ivanova, P. I. Makarevich, Y. V. Parfyonova, E. Aboian, S. M. Zakian
Hyperglycemia enhances arsenic-induced platelet and megakaryocyte activation
Jonathan D. Newman, Christina T. Echagarruga, Yoscar M. Ogando, Emilie Montenont, Yu Chen, Edward A. Fisher, Jeffrey S. Berger
Non-invasive in vivo imaging of cardiac stem/progenitor cell biodistribution and retention after intracoronary and intramyocardial delivery in a swine model of chronic ischemia reperfusion injury
María Collantes, Beatriz Pelacho, María José García-Velloso, Juán José Gavira, Gloria Abizanda, Itziar Palacios, Luis Rodriguez-Borlado, Virginia Álvarez, Elena Prieto, Margarita Ecay, Eduardo Larequi, Iván Peñuelas, Felipe Prósper
Aberrant T cell responses in the bone marrow microenvironment of patients with poor graft function after allogeneic hematopoietic stem cell transplantation
Yuan Kong, Yu-Tong Wang, Xie-Na Cao, Yang Song, Yu-Hong Chen, Yu-Qian Sun, Yu Wang, Xiao-Hui Zhang, Lan-Ping Xu, Xiao-Jun Huang
FTY720 inhibits mesothelioma growth in vitro and in a syngeneic mouse model
Agata Szymiczek, Sandra Pastorino, David Larson, Mika Tanji, Laura Pellegrini, Jiaming Xue, Shuangjing Li, Carlotta Giorgi, Paolo Pinton, Yasutaka Takinishi, Harvey I. Pass, Hideki Furuya, Giovanni Gaudino, Andrea Napolitano, Michele Carbone, Haining Yang
Elutriated lymphocytes for manufacturing chimeric antigen receptor T cells
David F. Stroncek, Daniel W. Lee, Jiaqiang Ren, Marianna Sabatino, Steven Highfill, Hanh Khuu, Nirali N. Shah, Rosandra N. Kaplan, Terry J. Fry, Crystal L. Mackall
Activin B is a novel biomarker for chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME) diagnosis: a cross sectional study
Brett A. Lidbury, Badia Kita, Donald P. Lewis, Susan Hayward, Helen Ludlow, Mark P. Hedger, David M. de Kretser
Veliparib in combination with radiotherapy for the treatment of MGMT unmethylated glioblastoma
Toni Rose Jue, Kyoko Nozue, Ashleigh J. Lester, Swapna Joshi, Lisette B. W. Schroder, Shane P. Whittaker, Sheri Nixdorf, Robert W. Rapkins, Mustafa Khasraw, Kerrie L. McDonald
Epidermal growth factor receptor and epididymis invasion as prognostic biomarkers in clinical stage I testicular germ cell tumours
Miguel F. Sanmamed, E. Esteban, E. Uriol, R. Zarate, M. Capelan, C. Muriel, G. Crespo, J. P. Berros, P. Pardo-Coto, Q. Perez, C. Alvarez-Fernández, P. Jiménez Fonseca, M. Luque, A. Astudillo
Urinary collagen degradation products as early markers of progressive renal fibrosis
Ryanne S. Hijmans, Daniel Guldager Kring Rasmussen, Saleh Yazdani, Gerjan Navis, Harry van Goor, Morten Asser Karsdal, Federica Genovese, Jacob van den Born
Dynamic and specific immune responses against multiple tumor antigens were elicited in patients with hepatocellular carcinoma after cell-based immunotherapy
Yanyan Han, Yeting Wu, Chou Yang, Jing Huang, Yabing Guo, Li Liu, Ping Chen, Dongyun Wu, Junyun Liu, Jin Li, Xiangjun Zhou, Jinlin Hou
Myocyte enhancer factor 2D provides a cross-talk between chronic inflammation and lung cancer
Hai-xing Zhu, Lin Shi, Yong Zhang, Yi-chun Zhu, Chun-xue Bai, Xiang-dong Wang, Jie-bai Zhou
24h-gene variation effect of combined bevacizumab/erlotinib in advanced non-squamous non-small cell lung cancer using exon array blood profiling
Florent Baty, Markus Joerger, Martin Früh, Dirk Klingbiel, Francesco Zappa, Martin Brutsche
In vivo MRI and ex vivo histological assessment of the cardioprotection induced by ischemic preconditioning, postconditioning and remote conditioning in a closed-chest porcine model of reperfused acute myocardial infarction: importance of microvasculature
Tamás Baranyai, Zoltán Giricz, Zoltán V. Varga, Gábor Koncsos, Dominika Lukovic, András Makkos, Márta Sárközy, Noémi Pávó, András Jakab, Csilla Czimbalmos, Hajnalka Vágó, Zoltán Ruzsa, Levente Tóth, Rita Garamvölgyi, Béla Merkely, Rainer Schulz, Mariann Gyöngyösi, Péter Ferdinandy
Proteomic analysis of protein purified derivative of Mycobacterium bovis
Sante Roperto, Mariaconcetta Varano, Valeria Russo, Roberta Lucà, Monica Cagiola, Marco Gaspari, Dora Maria Ceccarelli, Giovanni Cuda, Franco Roperto
Multiple gene variations contributed to congenital heart disease via GATA family transcriptional regulation
Yanyan Qian, Deyong Xiao, Xiao Guo, Hongbo Chen, Lili Hao, Xiaojing Ma, Guoying Huang, Duan Ma, Huijun Wang
Detection of newly produced T and B lymphocytes by digital PCR in blood stored dry on nylon flocked swabs
Marion Vaglio Tessitore, Alessandra Sottini, Aldo M. Roccaro, Claudia Ghidini, Simona Bernardi, Giovanni Martellosio, Federico Serana, Luisa Imberti
Association of atrial fibrillation susceptibility genes, atrial fibrillation phenotypes and response to catheter ablation: a gene-based analysis of GWAS data
Daniela Husser, Petra Büttner, Laura Ueberham, Borislav Dinov, Philipp Sommer, Arash Arya, Gerhard Hindricks, Andreas Bollmann
Combination of serum histidine and plasma tryptophan as a potential biomarker to detect clear cell renal cell carcinoma
Hyung-Ok Lee, Robert G. Uzzo, Debra Kister, Warren D. Kruger
Influence of diet on the gut microbiome and implications for human health
Rasnik K. Singh, Hsin-Wen Chang, Di Yan, Kristina M. Lee, Derya Ucmak, Kirsten Wong, Michael Abrouk, Benjamin Farahnik, Mio Nakamura, Tian Hao Zhu, Tina Bhutani, Wilson Liao
Partnering with patients in translational oncology research: ethical approach
Marie-France Mamzer, Nathalie Duchange, Sylviane Darquy, Patrice Marvanne, Claude Rambaud, Giovanna Marsico, Catherine Cerisey, Florian Scotté, Anita Burgun, Cécile Badoual, Pierre Laurent-Puig, Christian Hervé
Levels of hepatic Th17 cells and regulatory T cells upregulated by hepatic stellate cells in advanced HBV-related liver fibrosis
Xiaoyan Li, Yujie Su, Xuefeng Hua, Chan Xie, Jing Liu, Yuehua Huang, Liang Zhou, Min Zhang, Xu Li, Zhiliang Gao
Specific circulating microRNA signature of bicuspid aortic valve disease
Neus Martínez-Micaelo, Raúl Beltrán-Debón, Isabel Baiges, Marta Faiges, Josep M. Alegret
The role of vitamin C in the treatment of pain: new insights
Anitra C. Carr, Cate McCall
Novel trigenic CACNA1C/DES/MYPN mutations in a family of hypertrophic cardiomyopathy with early repolarization and short QT syndrome
Yanhong Chen, Hector Barajas-Martinez, Dongxiao Zhu, Xihui Wang, Chonghao Chen, Ruijuan Zhuang, Jingjing Shi, Xueming Wu, Yijia Tao, Weidong Jin, Xiaoyan Wang, Dan Hu
Adenovirus-mediated CD40L gene transfer increases Teffector/Tregulatory cell ratio and upregulates death receptors in metastatic melanoma patients
A. Schiza, J. Wenthe, S. Mangsbo, E. Eriksson, Anders Nilsson, T. H. Tötterman, A. Loskog, G. Ullenhag
Erratum to: Partnering with patients in translational oncology research: ethical approach
Marie-France Mamzer, Nathalie Duchange, Sylviane Darquy, Patrice Marvanne, Claude Rambaud, Giovanna Marsico, Catherine Cerisey, Florian Scotté, Anita Burgun, Cécile Badoual, Pierre Laurent-Puig, Christian Hervé
Preliminary results demonstrating the impact of Mediterranean diet on bone health
Maria Cristina Savanelli, Luigi Barrea, Paolo Emidio Macchia, Silvia Savastano, Andrea Falco, Andrea Renzullo, Elisabetta Scarano, Immacolata Cristina Nettore, Annamaria Colao, Carolina Di Somma
Electrochemotherapy efficacy evaluation for treatment of locally advanced stage III cutaneous squamous cell carcinoma: a 22-cases retrospective analysis
Gianluca Di Monta, Corrado Caracò, Ester Simeone, Antonio Maria Grimaldi, Ugo Marone, Massimiliano Di Marzo, Vito Vanella, Lucia Festino, Marco Palla, Stefano Mori, Nicola Mozzillo, Paolo Antonio Ascierto
Longitudinal analysis of serum oxylipin profile as a novel descriptor of the inflammatory response to surgery
Arnaud M. Wolfer, Alasdair J. Scott, Claudia Rueb, Mathieu Gaudin, Ara Darzi, Jeremy K. Nicholson, Elaine Holmes, James M. Kinross
Cystic fibrosis: current therapeutic targets and future approaches
Misbahuddin M. Rafeeq, Hussam Aly Sayed Murad
RETRACTED ARTICLE: TREM-1 associated macrophage polarization plays a significant role in inducing insulin resistance in obese population
Saravanan Subramanian, Pradeep K. Pallati, Poonam Sharma, Devendra K. Agrawal, Kalyana C. Nandipati
Analysis of necroptotic proteins in failing human hearts
Adrián Szobi, Eva Gonçalvesová, Zoltán V. Varga, Przemyslaw Leszek, Mariusz Kuśmierczyk, Michal Hulman, Ján Kyselovič, Péter Ferdinandy, Adriana Adameová
On the brink of extinction: the future of translational physician-scientists in the United States
Hideki Furuya, Dean Brenner, Charles J. Rosser
MicroRNA-223 demonstrated experimentally in exosome-like vesicles is associated with decreased risk of persistent pain after lumbar disc herniation
Aurora Moen, Daniel Jacobsen, Santosh Phuyal, Anna Legfeldt, Fred Haugen, Cecilie Røe, Johannes Gjerstad
The production method affects the efficacy of platelet derivatives to expand mesenchymal stromal cells in vitro
Martina Bernardi, Francesco Agostini, Katia Chieregato, Eliana Amati, Cristina Durante, Mario Rassu, Marco Ruggeri, Sabrina Sella, Elisabetta Lombardi, Mario Mazzucato, Giuseppe Astori
Her2 assessment using quantitative reverse transcriptase polymerase chain reaction reliably identifies Her2 overexpression without amplification in breast cancer cases
Gabriele Zoppoli, Anna Garuti, Gabriella Cirmena, Ludovica Verdun di Cantogno, Cristina Botta, Maurizio Gallo, Domenico Ferraioli, Enrico Carminati, Paola Baccini, Monica Curto, Piero Fregatti, Edoardo Isnaldi, Michela Lia, Roberto Murialdo, Daniele Friedman, Anna Sapino, Alberto Ballestrero
Transcriptomic profiling and quantitative high-throughput (qHTS) drug screening of CDH1 deficient hereditary diffuse gastric cancer (HDGC) cells identify treatment leads for familial gastric cancer
Ina Chen, Lesley Mathews-Greiner, Dandan Li, Abisola Abisoye-Ogunniyan, Satyajit Ray, Yansong Bian, Vivek Shukla, Xiaohu Zhang, Raj Guha, Craig Thomas, Berkley Gryder, Athina Zacharia, Joal D. Beane, Sarangan Ravichandran, Marc Ferrer, Udo Rudloff
Up-regulated expression of substance P in CD8+ T cells and NK1R on monocytes of atopic dermatitis
Zenan Zhang, Wenjiao Zheng, Hua Xie, Ruonan Chai, Junling Wang, Huiyun Zhang, Shaoheng He
Evaluation of engineered AAV capsids for hepatic factor IX gene transfer in murine and canine models
David M. Markusic, Timothy C. Nichols, Elizabeth P. Merricks, Brett Palaschak, Irene Zolotukhin, Damien Marsic, Sergei Zolotukhin, Arun Srivastava, Roland W. Herzog
A novel role of cellular interactions in vascular calcification
Adham Sameer A. Bardeesi, Jingwei Gao, Kun Zhang, Suntian Yu, Mengchao Wei, Pinming Liu, Hui Huang
Experimental approach to IGF-1 therapy in CCl4-induced acute liver damage in healthy controls and mice with partial IGF-1 deficiency
Luis A. Morales-Garza, Juan E. Puche, Gabriel A. Aguirre, Úrsula Muñoz, Mariano García-Magariño, Rocío G. De la Garza, Inma Castilla-Cortazar
Role of estrogen receptors and Src signaling in mechanisms of bone metastasis by estrogen receptor positive breast cancers
Jen-Hwey Chiu, Che-Sheng Wen, Jir-You Wang, Chih-Yi Hsu, Yi-Fang Tsai, Shih-Chieh Hung, Ling-Ming Tseng, Yi-Ming Shyr
Distinct gene expression profiles associated with Notch ligands Delta-like 4 and Jagged1 in plaque material from peripheral artery disease patients: a pilot study
Giorgio Aquila, Cinzia Fortini, Antonio Pannuti, Serena Delbue, Micaela Pannella, Marco Bruno Morelli, Cristiana Caliceti, Fausto Castriota, Monica de Mattei, Alessia Ongaro, Agnese Pellati, Pasquale Ferrante, Lucio Miele, Luigi Tavazzi, Roberto Ferrari, Paola Rizzo, Alberto Cremonesi
Progress of stem/progenitor cell-based therapy for retinal degeneration
Zhimin Tang, Yi Zhang, Yuyao Wang, Dandan Zhang, Bingqiao Shen, Min Luo, Ping Gu
Anti-inflammatory effects of H2S during acute bacterial infection: a review
Francesca Benedetti, Sabrina Curreli, Selvi Krishnan, Sergio Davinelli, Fiorenza Cocchi, Giovanni Scapagnini, Robert C. Gallo, Davide Zella
Erratum to: Novel trigenic CACNA1C/DES/MYPN mutations in a family of hypertrophic cardiomyopathy with early repolarization and short QT syndrome
Yanhong Chen, Hector Barajas‑Martinez, Dongxiao Zhu, Xihui Wang, Chonghao Chen, Ruijuan Zhuang, Jingjing Shi, Xueming Wu, Yijia Tao, Weidong Jin, Xiaoyan Wang, Dan Hu
Whole blood gene expression in adolescent chronic fatigue syndrome: an exploratory cross-sectional study suggesting altered B cell differentiation and survival
Chinh Bkrong Nguyen, Lene Alsøe, Jessica M. Lindvall, Dag Sulheim, Even Fagermoen, Anette Winger, Mari Kaarbø, Hilde Nilsen, Vegard Bruun Wyller
Erratum to: Analysis of necroptotic proteins in failing human hearts
Adrián Szobi, Eva Gonçalvesová, Zoltán V. Varga, Przemyslaw Leszek, Mariusz Kuśmierczyk, Michal Hulman, Ján Kyselovič, Péter Ferdinandy, Adriana Adameová
A phase II trial of autologous dendritic cell vaccination and radiochemotherapy following fluorescence-guided surgery in newly diagnosed glioblastoma patients
Susana Inogés, Sonia Tejada, Ascensión López-Díaz de Cerio, Jaime Gállego Pérez-Larraya, Jaime Espinós, Miguel Angel Idoate, Pablo Daniel Domínguez, Reyes García de Eulate, Javier Aristu, Maurizio Bendandi, Fernando Pastor, Marta Alonso, Enrique Andreu, Felipe Prósper Cardoso, Ricardo Díez Valle
Bovis Bacillus Calmette–Guerin (BCG) infection induces exosomal miRNA release by human macrophages
Shamila D. Alipoor, Esmaeil Mortaz, Payam Tabarsi, Parissa Farnia, Mehdi Mirsaeidi, Johan Garssen, Masoud Movassaghi, Ian M. Adcock
Correlation of cell-free DNA plasma concentration with severity of non-alcoholic fatty liver disease
Thomas Karlas, Lara Weise, Stephanie Kuhn, Felix Krenzien, Matthias Mehdorn, David Petroff, Nicolas Linder, Alexander Schaudinn, Harald Busse, Volker Keim, Johann Pratschke, Johannes Wiegand, Katrin Splith, Moritz Schmelzle
Standardization of platelet releasate products for clinical applications in cell therapy: a mathematical approach
Francesco Agostini, Jerry Polesel, Monica Battiston, Elisabetta Lombardi, Stefania Zanolin, Alessandro Da Ponte, Giuseppe Astori, Cristina Durante, Mario Mazzucato
Erratum to: Effects of the intradiscal implantation of stromal vascular fraction plus platelet rich plasma in patients with degenerative disc disease
Kristin Comella, Robert Silbert, Michelle Parlo
Impact of legumes and plant proteins consumption on cognitive performances in the elderly
Elisa Mazza, Antonietta Fava, Yvelise Ferro, Marta Moraca, Stefania Rotundo, Carmela Colica, Francesco Provenzano, Rosa Terracciano, Marta Greco, Daniela Foti, Elio Gulletta, Diego Russo, Domenico Bosco, Arturo Pujia, Tiziana Montalcini
The various aspects of genetic and epigenetic toxicology: testing methods and clinical applications
Ning Ren, Manar Atyah, Wan-Yong Chen, Chen-Hao Zhou
The spleen in liver cirrhosis: revisiting an old enemy with novel targets
Liang Li, Mubing Duan, Weisan Chen, An Jiang, Xiaoming Li, Jun Yang, Zongfang Li
Blood metabolomic fingerprint is distinct in healthy coronary and in stenosing or microvascular ischemic heart disease
Martino Deidda, Cristina Piras, Christian Cadeddu Dessalvi, Damiana Congia, Emanuela Locci, Federica Ascedu, Gianfranco De Candia, Mauro Cadeddu, Giorgio Lai, Raimondo Pirisi, Luigi Atzori, Giuseppe Mercuro
The progressive fragmentation of the KIT/PDGFRA wild-type (WT) gastrointestinal stromal tumors (GIST)
Margherita Nannini, Milena Urbini, Annalisa Astolfi, Guido Biasco, Maria A. Pantaleo
Recognition and treatment of sleep-disordered breathing: an important component of chronic disease management
Peter C. Farrell, Glenn Richards
Dendritic cells combined with tumor cells and α-galactosylceramide induce a potent, therapeutic and NK-cell dependent antitumor immunity in B cell lymphoma
Laura Escribà-Garcia, Carmen Alvarez-Fernández, Marta Tellez-Gabriel, Jorge Sierra, Javier Briones
Benefits of local tumor excision and pharyngectomy on the survival of nasopharyngeal carcinoma patients: a retrospective observational study based on SEER database
Jian Sun, Zhongying Huang, Zheyu Hu, Rui Sun
Differential expression of microRNAs following cardiopulmonary bypass in children with congenital heart diseases
Masood Abu-Halima, Martin Poryo, Nicole Ludwig, Janine Mark, Ina Marsollek, Christian Giebels, Johannes Petersen, Hans-Joachim Schäfers, Ulrich Grundmann, Thomas Pickardt, Andreas Keller, Eckart Meese, Hashim Abdul-Khaliq
Similar cardiometabolic effects of high- and moderate-intensity training among apparently healthy inactive adults: a randomized clinical trial
Robinson Ramírez-Vélez, Alejandra Tordecilla-Sanders, Luis Andrés Téllez-T, Diana Camelo-Prieto, Paula Andrea Hernández-Quiñonez, Jorge Enrique Correa-Bautista, Antonio Garcia-Hermoso, Rodrigo Ramirez-Campillo, Mikel Izquierdo
Non-caloric sweetener provides magnetic resonance imaging contrast for cancer detection
Puneet Bagga, Mohammad Haris, Kevin D’Aquilla, Neil E. Wilson, Francesco M. Marincola, Mitchell D. Schnall, Hari Hariharan, Ravinder Reddy
Sphingosine kinase 1 expression enhances colon tumor growth
Hideki Furuya, Yoshiko Shimizu, Paulette M. Tamashiro, Kayoko Iino, Jacek Bielawski, Owen T. M. Chan, Ian Pagano, Toshihiko Kawamori
Aberrant monocyte responses predict and characterize dengue virus infection in individuals with severe disease
Yean K. Yong, Hong Y. Tan, Soe Hui Jen, Esaki M. Shankar, Santha K. Natkunam, Jameela Sathar, Rishya Manikam, Shamala D. Sekaran
Basal cell carcinoma: 10-year experience with electrochemotherapy
Luca G. Campana, Roberto Marconato, Sara Valpione, Sara Galuppo, Mauro Alaibac, Carlo R. Rossi, Simone Mocellin
Shikonin-induced necroptosis is enhanced by the inhibition of autophagy in non-small cell lung cancer cells
Hyo-Jin Kim, Ki-Eun Hwang, Do-Sim Park, Seon-Hee Oh, Hong Young Jun, Kwon-Ha Yoon, Eun-Taik Jeong, Hak-Ryul Kim, Young-Suk Kim
Mathematical models for devising the optimal Ebola virus disease eradication
Shuo Jiang, Kaiqin Wang, Chaoqun Li, Guangbin Hong, Xuan Zhang, Menglin Shan, Hongbin Li, Jin Wang
Erratum to: The progressive fragmentation of the KIT/PDGFRA wild-type (WT) gastrointestinal stromal tumors (GIST)
Margherita Nannini, Milena Urbini, Annalisa Astolf, Guido Biasco, Maria A. Pantaleo
Distinct pathophysiological cytokine profiles for discrimination between autoimmune pancreatitis, chronic pancreatitis, and pancreatic ductal adenocarcinoma
Sahar Ghassem-Zadeh, Matthias M. Gaida, Szilard Szanyi, Hans Acha-Orbea, Jean-Louis Frossard, Ulf Hinz, Thilo Hackert, Oliver Strobel, Klaus Felix
CDK4/6 inhibitor-SHR6390 exerts potent antitumor activity in esophageal squamous cell carcinoma by inhibiting phosphorylated Rb and inducing G1 cell cycle arrest
Jiayuan Wang, Qingqing Li, Jiajia Yuan, Jingyuan Wang, Zuhua Chen, Zhentao Liu, Zhongwu Li, Yumei Lai, Jing Gao, Lin Shen
Osteoclast profile of medication-related osteonecrosis of the jaw secondary to bisphosphonate therapy: a comparison with osteoradionecrosis and osteomyelitis
Christian Gross, Manuel Weber, Kay Creutzburg, Patrick Möbius, Raimund Preidl, Kerstin Amann, Falk Wehrhan
Examining clinical similarities between myalgic encephalomyelitis/chronic fatigue syndrome and d-lactic acidosis: a systematic review
Amy Wallis, Michelle Ball, Sandra McKechnie, Henry Butt, Donald P. Lewis, Dorothy Bruck
Exercise in claudicants increase or decrease walking ability and the response relates to mitochondrial function
Michel van Schaardenburgh, Martin Wohlwend, Øivind Rognmo, Erney J. R. Mattsson
State of play and clinical prospects of antibody gene transfer
Kevin Hollevoet, Paul J. Declerck
Betaine promotes cell differentiation of human osteoblasts in primary culture
Isabella Villa, Pamela Senesi, Anna Montesano, Anita Ferraretto, Fernanda Vacante, Alice Spinello, Michela Bottani, Simona Bolamperti, Alessandro Rubinacci, Livio Luzi, Ileana Terruzzi
Distinct expression profile of HCMV encoded miRNAs in plasma from oral lichen planus patients
Meng Ding, Xiang Wang, Cheng Wang, Xiaoshuang Liu, Ke Zen, Wenmei Wang, Chen-Yu Zhang, Chunni Zhang
Development of an objective gene expression panel as an alternative to self-reported symptom scores in human influenza challenge trials
Julius Muller, Eneida Parizotto, Richard Antrobus, James Francis, Campbell Bunce, Amanda Stranks, Marshall Nichols, Micah McClain, Adrian V. S. Hill, Adaikalavan Ramasamy, Sarah C. Gilbert
Can psychobiotics intake modulate psychological profile and body composition of women affected by normal weight obese syndrome and obesity? A double blind randomized clinical trial
Antonino De Lorenzo, Micaela Costacurta, Giuseppe Merra, Paola Gualtieri, Giorgia Cioccoloni, Massimiliano Marchetti, Dimitrios Varvaras, Raffaella Docimo, Laura Di Renzo
Erratum to: Similar cardiometabolic effects of high- and moderate-intensity training among apparently healthy inactive adults: a randomized clinical trial
Robinson Ramírez-Vélez, Alejandra Tordecilla-Sanders, Luis Andrés Téllez-T, Diana Camelo-Prieto, Paula Andrea Hernández-Quiñonez, Jorge Enrique Correa-Bautista, Antonio Garcia-Hermoso, Rodrigo Ramirez-Campillo, Mikel Izquierdo
Xenon in the treatment of panic disorder: an open label study
Alexander Dobrovolsky, Thomas E. Ichim, Daqing Ma, Santosh Kesari, Vladimir Bogin
Synaptonemal complex protein 3 is associated with lymphangiogenesis in non-small cell lung cancer patients with lymph node metastasis
Haruhisa Kitano, Joon-Yong Chung, Kyung Hee Noh, Young-Ho Lee, Tae Woo Kim, Seok Hyung Lee, Soo-Heang Eo, Hyung Jun Cho, Chel Hun Choi, Shuhei Inoue, Jun Hanaoka, Junya Fukuoka, Stephen M. Hewitt
Precision medicine in breast cancer: reality or utopia?
Ali Bettaieb, Catherine Paul, Stéphanie Plenchette, Jingxuan Shan, Lotfi Chouchane, François Ghiringhelli
Molecular imaging biomarkers for cell-based immunotherapies
Mohammad Haris, Puneet Bagga, Hari Hariharan, Bevin McGettigan-Croce, Laura A. Johnson, Ravinder Reddy
RETRACTED ARTICLE: Intra-articular injection in the knee of adipose derived stromal cells (stromal vascular fraction) and platelet rich plasma for osteoarthritis
Himanshu Bansal, Kristin Comella, Jerry Leon, Poonam Verma, Diwaker Agrawal, Prasad Koka, Thomas Ichim
The era of bioengineering: how will this affect the next generation of cancer immunotherapy?
Michele Graciotti, Cristiana Berti, Harm-Anton Klok, Lana Kandalaft
RETRACTED ARTICLE: Stromal vascular fraction cells for the treatment of critical limb ischemia: a pilot study
Adas Darinskas, Mindaugas Paskevicius, Gintaras Apanavicius, Gintaris Vilkevicius, Liutauras Labanauskas, Thomas E. Ichim, Rytis Rimdeika
Imaging of αvβ3 integrin expression in experimental myocardial ischemia with [68Ga]NODAGA-RGD positron emission tomography
Maria Grönman, Miikka Tarkia, Tuomas Kiviniemi, Paavo Halonen, Antti Kuivanen, Timo Savunen, Tuula Tolvanen, Jarmo Teuho, Meeri Käkelä, Olli Metsälä, Mikko Pietilä, Pekka Saukko, Seppo Ylä-Herttuala, Juhani Knuuti, Anne Roivainen, Antti Saraste
Establishment of an orthotopic patient-derived xenograft mouse model using uveal melanoma hepatic metastasis
Ken Kageyama, Masahiro Ohara, Kengo Saito, Shinji Ozaki, Mizue Terai, Michael J. Mastrangelo, Paolo Fortina, Andrew E. Aplin, Takami Sato
Clinical features of serous retinopathy observed with cobimetinib in patients with BRAF-mutated melanoma treated in the randomized coBRIM study
Luis de la Cruz-Merino, Lorenza Di Guardo, Jean-Jacques Grob, Alfredo Venosa, James Larkin, Grant A. McArthur, Antoni Ribas, Paolo A. Ascierto, Jeffrey T. R. Evans, Antonio Gomez-Escobar, Giulio Barteselli, Susan Eng, Jessie J. Hsu, Anne Uyei, Brigitte Dréno
Transplantation of human fetal pancreatic progenitor cells ameliorates renal injury in streptozotocin-induced diabetic nephropathy
Yongwei Jiang, Wenjian Zhang, Shiqing Xu, Hua Lin, Weiguo Sui, Honglin Liu, Liang Peng, Qing Fang, Li Chen, Jinning Lou
Allergens in red ginseng extract induce the release of mediators associated with anaphylactoid reactions
Lu Wang, Yazheng Zhao, Ye Yang, Yuanjia Hu, Xiaohan Zou, Boyang Yu, Jin Qi
Identification of clear cell renal cell carcinoma and oncocytoma using a three-gene promoter methylation panel
Ana Sílvia Pires-Luís, Pedro Costa-Pinheiro, Maria João Ferreira, Luís Antunes, Francisco Lobo, Jorge Oliveira, Rui Henrique, Carmen Jerónimo
A phase I/II trial of fixed-dose stereotactic body radiotherapy with sequential or concurrent pembrolizumab in metastatic urothelial carcinoma: evaluation of safety and clinical and immunologic response
Nora Sundahl, Katrien De Wolf, Sylvie Rottey, Karel Decaestecker, Daan De Maeseneer, Annabel Meireson, Els Goetghebeur, Valérie Fonteyne, Sofie Verbeke, Pieter De Visschere, Dries Reynders, Mireille Van Gele, Lieve Brochez, Piet Ost
CSPG4: a prototype oncoantigen for translational immunotherapy studies
Valeria Rolih, Giuseppina Barutello, Selina Iussich, Raffaella De Maria, Elena Quaglino, Paolo Buracco, Federica Cavallo, Federica Riccardo
The clinical importance of tumour-infiltrating macrophages and dendritic cells in periampullary adenocarcinoma differs by morphological subtype
Sebastian Lundgren, Emelie Karnevi, Jacob Elebro, Björn Nodin, Mikael C. I. Karlsson, Jakob Eberhard, Karin Leandersson, Karin Jirström
Effect of a 6-month pedometer-based walking intervention on functional capacity in patients with chronic heart failure with reduced (HFrEF) and with preserved (HFpEF) ejection fraction: study protocol for two multicenter randomized controlled trials
Tomas Vetrovsky, Michal Siranec, Jiri Parenica, Martin Griva, Jiri Stastny, Jan Precek, Radek Pelouch, Vaclav Bunc, Ales Linhart, Jan Belohlavek
Identification of new MUC1 epitopes using HLA-transgenic animals: implication for immunomonitoring
Tanja Scheikl-Gatard, Caroline Tosch, François Lemonnier, Ronald Rooke
Impaired B cell immunity in acute myeloid leukemia patients after chemotherapy
Meghali Goswami, Gabrielle Prince, Angelique Biancotto, Susan Moir, Lela Kardava, Brian H. Santich, Foo Cheung, Yuri Kotliarov, Jinguo Chen, Rongye Shi, Huizhi Zhou, Hana Golding, Jody Manischewitz, Lisa King, Lauren M. Kunz, Kimberly Noonan, Ivan M. Borrello, B. Douglas Smith, Christopher S. Hourigan
Analysis of circulating microRNAs in patients with repaired Tetralogy of Fallot with and without heart failure
Masood Abu-Halima, Eckart Meese, Andreas Keller, Hashim Abdul-Khaliq, Tanja Rädle-Hurst
Erratum to: Altered neuroendocrine control and association to clinical symptoms in adolescent chronic fatigue syndrome: a cross-sectional study
Vegard Bruun Wyller, Valeria Vitelli, Dag Sulheim, Even Fagermoen, Anette Winger, Kristin Godang, Jens Bollerslev
Regulation of glucose uptake in lymphoma cell lines by c-MYC- and PI3K-dependent signaling pathways and impact of glycolytic pathways on cell viability
Martina Broecker-Preuss, Nina Becher-Boveleth, Andreas Bockisch, Ulrich Dührsen, Stefan Müller
High expression of ETS2 predicts poor prognosis in acute myeloid leukemia and may guide treatment decisions
Lin Fu, Huaping Fu, Qingyun Wu, Yifan Pang, Keman Xu, Lei Zhou, Jianlin Qiao, Xiaoyan Ke, Kailin Xu, Jinlong Shi
Implementation of longevity-promoting supplements and medications in public health practice: achievements, challenges and future perspectives
Alexander Vaiserman, Oleh Lushchak
Mesenchymal stem cells from sternum: the type of heart disease, ischemic or valvular, does not influence the cell culture establishment and growth kinetics
Lucinara Dadda Dias, Karina Rabello Casali, Carine Ghem, Melissa Kristocheck da Silva, Grasiele Sausen, Patrícia Bonini Palma, Dimas Tadeu Covas, Renato A. K. Kalil, Beatriz D. Schaan, Nance Beyer Nardi, Melissa Medeiros Markoski
The European ME/CFS Biomarker Landscape project: an initiative of the European network EUROMENE
Carmen Scheibenbogen, Helma Freitag, Julià Blanco, Enrica Capelli, Eliana Lacerda, Jerome Authier, Mira Meeus, Jesus Castro Marrero, Zaiga Nora-Krukle, Elisa Oltra, Elin Bolle Strand, Evelina Shikova, Slobodan Sekulic, Modra Murovska
Data-driven interdisciplinary mathematical modelling quantitatively unveils competition dynamics of co-circulating influenza strains
Bin-Shenq Ho, Kun-Mao Chao
RNAi therapy to the wall of arteries and veins: anatomical, physiologic, and pharmacological considerations
Christoph S. Nabzdyk, Leena Pradhan-Nabzdyk, Frank W. LoGerfo
Coiled-coil domain containing 109B is a HIF1α-regulated gene critical for progression of human gliomas
Ran Xu, Mingzhi Han, Yangyang Xu, Xin Zhang, Chao Zhang, Di Zhang, Jianxiong Ji, Yuzhen Wei, Shuai Wang, Bin Huang, Anjing Chen, Qing Zhang, Wenjie Li, Tao Sun, Feng Wang, Xingang Li, Jian Wang
Estimating the survival advantage based on telomere length and serum biomarkers of aging
Yilin Zhao, Shijun Li, Hui Liu
Comparative analysis of the EGFR, HER2, c-MYC, and MET variations in colorectal cancer determined by three different measures: gene copy number gain, amplification status and the 2013 ASCO/CAP guideline criterion for HER2 testing of breast cancer
Yoonjin Kwak, Sumi Yun, Soo Kyung Nam, An Na Seo, Kyu Sang Lee, Eun Shin, Heung-Kwon Oh, Duck Woo Kim, Sung Bum Kang, Woo Ho Kim, Hye Seung Lee
Survival impact of pre-treatment neutrophils on oropharyngeal and laryngeal cancer patients undergoing definitive radiotherapy
Whitney A. Sumner, William A. Stokes, Ayman Oweida, Kiersten L. Berggren, Jessica D. McDermott, David Raben, Diana Abbott, Bernard Jones, Gregory Gan, Sana D. Karam
Tough decoy targeting of predominant let-7 miRNA species in adult human hematopoietic cells
Jaira F. de Vasconcellos, Colleen Byrnes, Y. Terry Lee, Joshua M. Allwardt, Megha Kaushal, Antoinette Rabel, Jeffery L. Miller
Temperature variability in the day–night cycle is associated with further intracranial pressure during therapeutic hypothermia
Adriano Barreto Nogueira, Eva Annen, Oliver Boss, Faraneh Farokhzad, Christopher Sikorski, Emanuela Keller
Proteomic analysis of sputum reveals novel biomarkers for various presentations of asthma
Chao Cao, Wen Li, Wen Hua, Fugui Yan, Hao Zhang, Huaqiong Huang, Yinghua Ying, Na Li, Fen Lan, Shaobin Wang, Xiao Chen, Jing Li, Jinkai Liu, Tianwen Lai, Zhengqiang Bao, Yuan Cao, Yun Zhao, Gang Huang, Lili Huang, Yaqing Huang, Ping Wu, Chao Peng, Zhihua Chen, Kian Fan Chung, Nanshan Zhong, Songmin Ying, Huahao Shen
Inorganic nitrate as a treatment for acute heart failure: a protocol for a single center, randomized, double-blind, placebo-controlled pilot and feasibility study
Roman Falls, Michael Seman, Sabine Braat, Joshua Sortino, Jason D. Allen, Christopher J. Neil
Checkpoint inhibitors in melanoma and early phase development in solid tumors: what’s the future?
Paolo A. Ascierto, Grant A. McArthur
Erythrocyte depletion from bone marrow: performance evaluation after 50 clinical-scale depletions with Spectra Optia BMC
Soo-Zin Kim-Wanner, Gesine Bug, Juliane Steinmann, Salem Ajib, Nadine Sorg, Carolin Poppe, Milica Bunos, Eva Wingenfeld, Christiane Hümmer, Beate Luxembourg, Erhard Seifried, Halvard Bonig
Quantification of mutant SPOP proteins in prostate cancer using mass spectrometry-based targeted proteomics
Hui Wang, Christopher E. Barbieri, Jintang He, Yuqian Gao, Tujin Shi, Chaochao Wu, Athena A. Schepmoes, Thomas L. Fillmore, Sung-Suk Chae, Dennis Huang, Juan Miguel Mosquera, Wei-Jun Qian, Richard D. Smith, Sudhir Srivastava, Jacob Kagan, David G. Camp II, Karin D. Rodland, Mark A. Rubin, Tao Liu
Role of IQGAP3 in metastasis and epithelial–mesenchymal transition in human hepatocellular carcinoma
Yongjie Shi, Nan Qin, Qiang Zhou, Yanqiu Chen, Sicong Huang, Bo Chen, Gang Shen, Hongyun Jia
Gene mutational pattern and expression level in 560 acute myeloid leukemia patients and their clinical relevance
Yong-Mei Zhu, Pan-Pan Wang, Jin-Yan Huang, Yun-Shuo Chen, Bing Chen, Yu-Jun Dai, Han Yan, Yi Hu, Wen-Yan Cheng, Ting-Ting Ma, Sai-Juan Chen, Yang Shen
PIM-1 mRNA expression is a potential prognostic biomarker in acute myeloid leukemia
Hui Cheng, Chongmei Huang, Xiaoqian Xu, Xiaoxia Hu, Shenglan Gong, Gusheng Tang, Xianmin Song, Weiping Zhang, Jianmin Wang, Li Chen, Jianmin Yang
Vaccine-draining lymph nodes of cancer patients for generating anti-cancer antibodies
Girja S. Shukla, Walter C. Olson, Stephanie C. Pero, Yu-jing Sun, Chelsea L. Carman, Craig L. Slingluff Jr., David N. Krag
Glucocorticoid attenuates acute lung injury through induction of type 2 macrophage
Guo-wei Tu, Yi Shi, Yi-jun Zheng, Min-jie Ju, Hong-yu He, Guo-guang Ma, Guang-wei Hao, Zhe Luo
In silico prediction of novel therapeutic targets using gene–disease association data
Enrico Ferrero, Ian Dunham, Philippe Sanseau
Molecular targeting in acute myeloid leukemia
Seah H. Lim, Patrycja M. Dubielecka, Vikram M. Raghunathan
Ruxolitinib/nilotinib cotreatment inhibits leukemia-propagating cells in Philadelphia chromosome-positive ALL
Yuan Kong, Yi-Lin Wu, Yang Song, Min-Min Shi, Xie-Na Cao, Hong-Yan Zhao, Ya-Zhen Qin, Yue-Yun Lai, Hao Jiang, Qian Jiang, Xiao-Jun Huang
Multiple therapeutic effect of endothelial progenitor cell regulated by drugs in diabetes and diabetes related disorder
Rashmi K. Ambasta, Harleen Kohli, Pravir Kumar
Genome-wide computational analysis of potential long noncoding RNA mediated DNA:DNA:RNA triplexes in the human genome
Saakshi Jalali, Amrita Singh, Souvik Maiti, Vinod Scaria
Altered Semmes–Weinstein monofilament test results are associated with oxidative stress markers in type 2 diabetic subjects
Sergio Martinez-Hervás, Mercedes Molina Mendez, José Folgado, Carmen Tormos, Pilar Ascaso, Marta Peiró, Jose T. Real, Juan F. Ascaso
Absolute quantification of microparticles by flow cytometry in ascites of patients with decompensated cirrhosis: a cohort study
Cornelius Engelmann, Katrin Splith, Sandra Krohn, Adam Herber, Albrecht Boehlig, Stephan Boehm, Johann Pratschke, Thomas Berg, Moritz Schmelzle
Over-expression of BAG-1 in head and neck squamous cell carcinomas (HNSCC) is associated with cisplatin-resistance
Shutong Liu, Bo Ren, Hang Gao, Suchan Liao, Ying-Xian Zhai, Shirong Li, Xue-Jin Su, Ping Jin, David Stroncek, Zhixiang Xu, Qinghua Zeng, Yulin Li
Cancer heterogeneity: converting a limitation into a source of biologic information
Albert Rübben, Arturo Araujo
Transcriptomic meta-analysis identifies gene expression characteristics in various samples of HIV-infected patients with nonprogressive disease
Le-Le Zhang, Zi-Ning Zhang, Xian Wu, Yong-Jun Jiang, Ya-Jing Fu, Hong Shang
JTM advances in uncharted territories: diseases and disorders of unknown etiology
Monica C. Panelli
Expression of Concern to: Therapeutic potential of human embryonic stem cell transplantation in patients with cerebral palsy
Geeta Shroff, Anupama Gupta, Jitender Kumar Barthakur
Erratum to: Ockham’s razor for the MET-driven invasive growth linking idiopathic pulmonary fibrosis and cancer
Giulia M. Stella, Alessandra Gentile, Alice Balderacchi, Federica Meloni, Melissa Milan, Silvia Benvenuti
BDNF/TrkB axis activation promotes epithelial–mesenchymal transition in idiopathic pulmonary fibrosis
Emanuela Cherubini, Salvatore Mariotta, Davide Scozzi, Rita Mancini, Giorgia Osman, Michela D’Ascanio, Pierdonato Bruno, Giuseppe Cardillo, Alberto Ricci
Treatment of lumbar degenerative disc disease-associated radicular pain with culture-expanded autologous mesenchymal stem cells: a pilot study on safety and efficacy
Christopher Centeno, Jason Markle, Ehren Dodson, Ian Stemper, Christopher J. Williams, Matthew Hyzy, Thomas Ichim, Michael Freeman
Statistically controlled identification of differentially expressed genes in one-to-one cell line comparisons of the CMAP database for drug repositioning
Jun He, Haidan Yan, Hao Cai, Xiangyu Li, Qingzhou Guan, Weicheng Zheng, Rou Chen, Huaping Liu, Kai Song, Zheng Guo, Xianlong Wang
Report on the first SLFN11 monothematic workshop: from function to role as a biomarker in cancer
Alberto Ballestrero, Davide Bedognetti, Domenico Ferraioli, Paola Franceschelli, Sana Intidhar Labidi-Galy, Elisabetta Leo, Junko Murai, Yves Pommier, Petros Tsantoulis, Valerio Gaetano Vellone, Gabriele Zoppoli
Impact of mesenchymal stem cells’ secretome on glioblastoma pathophysiology
Joana Vieira de Castro, Eduardo D. Gomes, Sara Granja, Sandra I. Anjo, Fátima Baltazar, Bruno Manadas, António J. Salgado, Bruno M. Costa
A lipidated peptide of Mycobacterium tuberculosis resuscitates the protective efficacy of BCG vaccine by evoking memory T cell immunity
Pradeep K. Rai, Sathi Babu Chodisetti, Weiguang Zeng, Sajid Nadeem, Sudeep K. Maurya, Susanta Pahari, Ashok K. Janmeja, David C. Jackson, Javed N. Agrewala
Porcine model of progressive cardiac hypertrophy and fibrosis with secondary postcapillary pulmonary hypertension
Mariann Gyöngyösi, Noemi Pavo, Dominika Lukovic, Katrin Zlabinger, Andreas Spannbauer, Denise Traxler, Georg Goliasch, Ljubica Mandic, Jutta Bergler-Klein, Alfred Gugerell, Andras Jakab, Zsuzsanna Szankai, Levente Toth, Rita Garamvölgyi, Gerald Maurer, Frederic Jaisser, Faiez Zannad, Thomas Thum, Sándor Bátkai, Johannes Winkler
Metastatic pathway and the microvascular and physicochemical microenvironments of human melanoma xenografts
Ruixia Huang, Lise Mari K. Andersen, Einar K. Rofstad
Contextual tumor suppressor function of T cell death-associated gene 8 (TDAG8) in hematological malignancies
Calvin R. Justus, Edward J. Sanderlin, Lixue Dong, Tianai Sun, Jen-Tsan Chi, Kvin Lertpiriyapong, Li V. Yang
Perspectives in immunotherapy: meeting report from the “Immunotherapy Bridge”, Napoli, November 30th 2016
Paolo A. Ascierto, Bruno Daniele, Hans Hammers, Vera Hirsh, Joseph Kim, Lisa Licitra, Rita Nanda, Sandro Pignata
Understanding immune phenotypes in human gastric disease tissues by multiplexed immunohistochemistry
Le Ying, Feng Yan, Qiaohong Meng, Xiangliang Yuan, Liang Yu, Bryan R. G. Williams, David W. Chan, Liyun Shi, Yugang Tu, Peihua Ni, Xuefeng Wang, Dakang Xu, Yiqun Hu
The pathophysiological role of mitochondrial oxidative stress in lung diseases
Xiaojing Liu, Zhihong Chen
Association of red cell distribution width with all-cause and cardiovascular-specific mortality in African American and white adults: a prospective cohort study
Salman M. Tajuddin, Mike A. Nalls, Alan B. Zonderman, Michele K. Evans
Prediction of microbe–disease association from the integration of neighbor and graph with collaborative recommendation model
Yu-An Huang, Zhu-Hong You, Xing Chen, Zhi-An Huang, Shanwen Zhang, Gui-Ying Yan
A novel small molecule inhibitor of p32 mitochondrial protein overexpressed in glioma
Venkata Yenugonda, Natsuko Nomura, Valentina Kouznetsova, Igor Tsigelny, Valentina Fogal, Elmar Nurmemmedov, Santosh Kesari, Ivan Babic
A Yin-Yang 1/miR-30a regulatory circuit modulates autophagy in pancreatic cancer cells
Chuang Yang, Jing-Jing Zhang, Yun-Peng Peng, Yi Zhu, Ling-Di Yin, Ji-Shu Wei, Wen-Tao Gao, Kui-Rong Jiang, Yi Miao
World-Wide Immunoscore Task Force: meeting report from the “Melanoma Bridge”, Napoli, November 30th–December 3rd, 2016
Jerome Galon, Alessandro Lugli, Carlo Bifulco, Franck Pages, Giuseppe Masucci, Francesco M. Marincola, Paolo A. Ascierto
Effect of Infla-Kine supplementation on the gene expression of inflammatory markers in peripheral mononuclear cells and on C-reactive protein in blood
Nina A. Mikirova, Santosh Kesari, Thomas E. Ichim, Neil H. Riordan
Flow cytometric immunobead assay for quantitative detection of platelet autoantibodies in immune thrombocytopenia patients
Juping Zhai, Mengyuan Ding, Tianjie Yang, Bin Zuo, Zhen Weng, Yunxiao Zhao, Jun He, Qingyu Wu, Changgeng Ruan, Yang He
The effect of renal denervation in an experimental model of chronic renal insufficiency, The REmnant kidney Denervation In Pigs study (REDIP study)
Jean-Claude Lubanda, Miroslav Chochola, Mikuláš Mlček, Petr Neužil, Josef Marek, Štěpán Havránek, Sylvie Kuchynková, Zdeňka Fingrová, Kao-Hsuan Aimee Huang, Aleš Linhart
Haemoadsorption reduces the inflammatory response and improves blood flow during ex vivo renal perfusion in an experimental model
Sarah A. Hosgood, Tom Moore, Theresa Kleverlaan, Tom Adams, Michael L. Nicholson
Detecting the tipping points in a three-state model of complex diseases by temporal differential networks
Pei Chen, Yongjun Li, Xiaoping Liu, Rui Liu, Luonan Chen
Therapeutic application of T regulatory cells in composite tissue allotransplantation
Jeong-Hee Yang, Seok-Chan Eun
GlycA, a novel biomarker of systemic inflammation and cardiovascular disease risk
Margery A. Connelly, James D. Otvos, Irina Shalaurova, Martin P. Playford, Nehal N. Mehta
Veritable antiviral capacity of natural killer cells in chronic HBV infection: an argument for an earlier anti-virus treatment
Xiaoyan Li, Liang Zhou, Lin Gu, Yurong Gu, Lubiao Chen, Yifan Lian, Yuehua Huang
Systemic immune-inflammation index predicting chemoradiation resistance and poor outcome in patients with stage III non-small cell lung cancer
Yu-Suo Tong, Juan Tan, Xi-Lei Zhou, Ya-Qi Song, Ying-Jian Song
The need for a network to establish and validate predictive biomarkers in cancer immunotherapy
Giuseppe V. Masucci, Alessandra Cesano, Alexander Eggermont, Bernard A. Fox, Ena Wang, Francesco M. Marincola, Gennaro Ciliberto, Kevin Dobbin, Igor Puzanov, Janis Taube, Jennifer Wargo, Lisa H. Butterfield, Lisa Villabona, Magdalena Thurin, Michael A. Postow, Paul M. Sondel, Sandra Demaria, Sanjiv Agarwala, Paolo A. Ascierto
Efficient generation of P53 biallelic knockout Diannan miniature pigs via TALENs and somatic cell nuclear transfer
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