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Current Pain and Headache Reports
Erschienen in: Current Pain and Headache Reports 1/2021

01.01.2021 | Chronic Pain Medicine (O Viswanath, Section Editor)

Treatment and Management of Loin Pain Hematuria Syndrome

verfasst von: Ivan Urits, Nathan Li, Amnon A. Berger, Paul Walker, Brendan Wesp, Alec M. Zamarripa, Daniel An, Elyse M. Cornett, Alaa Abd-Elsayed, Alan D. Kaye

Erschienen in: Current Pain and Headache Reports | Ausgabe 1/2021

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Abstract

Purpose of Review

Loin pain hematuria syndrome (LPHS) is rare and seldom diagnosed, yet it has a particularly significant impact on those affected. This is a review of the latest and seminal evidence of the pathophysiology and diagnosis of LPHS and presents the typical clinical presentation and treatment options available.

Recent Findings

LPHS is typically found in young women with characteristic symptoms, including severe recurrent flank pain and gross or microscopic hematuria. The majority of patients will experience crippling pain for many years without effective therapy, often requiring frequent use of narcotic medication. However, the lack of conclusive pathophysiology, in conjunction with the rarity of LPHS, has prohibited the development and trial of definitive treatment options. Nevertheless, in order to combat this rare but severe disease, management strategies have continued to evolve, ranging from conservative measures to invasive procedures. This review presents an overview of the current hypotheses on the pathophysiology of LPHS in addition to summarizing the management strategies that have been utilized.

Summary

Only 30% of LPHS patients will experience spontaneous resolution, whereas the majority will continue to face chronic, crippling pain. Several methods of treatment, including invasive and non-invasive, may provide an improved outcome to these patients. Treatment should be individually tailored and multi-disciplinary in nature. Further research is required to further elucidate the pathophysiology and develop new, specific, treatment options.
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Metadaten
Titel
Treatment and Management of Loin Pain Hematuria Syndrome
verfasst von
Ivan Urits
Nathan Li
Amnon A. Berger
Paul Walker
Brendan Wesp
Alec M. Zamarripa
Daniel An
Elyse M. Cornett
Alaa Abd-Elsayed
Alan D. Kaye
Publikationsdatum
01.01.2021
Verlag
Springer US
Erschienen in
Current Pain and Headache Reports / Ausgabe 1/2021
Print ISSN: 1531-3433
Elektronische ISSN: 1534-3081
DOI
https://doi.org/10.1007/s11916-020-00925-0

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