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01.12.2015 | Original Article

Anxiety, depression, resilience and quality of life in children and adolescents with pre-dialysis chronic kidney disease

verfasst von: Janaina Matos Moreira, Cristina Maria Bouissou Morais Soares, Antônio Lúcio Teixeira, Ana Cristina Simões e Silva, Arthur Melo Kummer

Erschienen in: Pediatric Nephrology | Ausgabe 12/2015

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Abstract

Background

Chronic kidney disease (CKD) is a risk factor for psychosocial impairment and psychiatric symptoms. Children and adolescents on dialysis frequently have compromised daily life activities and a worse quality of life (QoL) compared with healthy peers. However, few studies have investigated these aspects of CKD in pediatric pre-dialysis CKD patients. Therefore, we have analyzed resilience, QoL and anxiety and depressive symptoms in children and adolescents with pre-dialysis CKD and compared these to the values of healthy controls.

Methods

Demographic and clinical data were collected from 28 children and adolescents with pre-dialysis CKD and 28 healthy sex- and age-matched controls. Psychological assessment of the participants was performed using the Wagnild and Young Resilience Scale, Pediatric Quality of Life (QoL) Inventory 4.0 , Child Depression Inventory and Self-report for Childhood Anxiety Related Disorders scales.

Results

Of the 56 children enrolled in our study, the CKD patients were referred to mental health professionals more frequently than the controls. Patients exhibited higher scores for separation anxiety and a higher frequency of clinically significant depressive symptoms. They also had lower overall QoL scores, as well as poorer scores for the psychological, educational and psychosocial subdomains of QoL instruments. There was a negative correlation between anxiety and depressive symptoms and all domains of QoL. Resilience was similar in both groups, but lower in patients with significant depressive symptoms. No significant association was found between clinical or laboratory findings and psychological variables in CKD patients.

Conclusion

Although patients and controls exhibited similar scores of resilience, CKD negatively impacted the QoL of pediatric patients, contributing to a higher frequency of depression and separation anxiety.

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Titel: Anxiety, depression, resilience and quality of life in children and adolescents with pre-dialysis chronic kidney disease
verfasst von: Janaina Matos Moreira
Cristina Maria Bouissou Morais Soares
Antônio Lúcio Teixeira
Ana Cristina Simões e Silva
Arthur Melo Kummer
Publikationsdatum: 01.12.2015
Verlag: Springer Berlin Heidelberg
Erschienen in: Pediatric Nephrology / Ausgabe 12/2015
Print ISSN: 0931-041X
Elektronische ISSN: 1432-198X
DOI: https://doi.org/10.1007/s00467-015-3159-6

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Anxiety, depression, resilience and quality of life in children and adolescents with pre-dialysis chronic kidney disease