Ausgabe Sonderheft 1/2011
31st International Symposium on Intensive Care and Emergency Medicine
Inhalt (542 Artikel)
Effects of thyroid hormones on major cardiovascular risk in acute coronary syndromes
A Bayrak, A Bayır, K Uçar Karabulut
Effect of reperfusion therapy on QTd and QTcd in patients with acute STEMI
D Ragab, H Elghawaby, M Eldesouky, T Elsayed
Biochemical studies of some diagnostic enzymes in myocardial infarction
M Samir, H Khaled Nagi, D Ragab, M Refaie
Pharmacological CCR1 blockade limits infarct size and preserves cardiac function in a chronic model of myocardial ischemia/reperfusion
A Van de Sandt, S Zander, S Becher, R Ercan, C Quast, J Ohlig, T Lauer, T Rassaf, M Kelm, MW Merx
Metabolic syndrome and coronary artery bypass graft surgery
M Brouard, JJ Jimenez, JL Iribarren, N Perez, L Lorente, P Machado, JM Raya, R Perez, JM Borreguero, R Martinez, ML Mora
Perioperative risk factors for serious gastrointestinal complications treated by laparotomy after cardiac surgery using cardiopulmonary bypass
P Soos, B Schmack, A Weymann, G Veres, B Merkely, M Karck, G Szabó
Endotoxemia related to cardiopulmonary bypass is associated with increased risk of infection after cardiac surgery
DJ Klein, F Briet, R Nisenbaum, A Romaschin, C Mazer
Manual hyperinflation attenuates reduction of functional residual capacity in cardiac surgical patients: a randomized controlled trial
F Paulus, DP Veelo, SB De Nijs, P Bresser, BA De Mol, LF Beenen, JM Binnekade, MJ Schultz
Incidence of cerebral desaturation events in the ICU following cardiac surgery
S Greenberg, A Garcia, L Howard, R Fasanella, J Vender
A nonrandomized comparison of off -pump versus on-pump coronary bypass surgery in Egyptian patients
H El-Abd, S Salah
Extracorporal membrane oxygenation for cardiopulmonary support after open heart surgery
UJ Jaschinski, G Kierschke, H Forst, M Beyer
Quality of life after cardiac surgery in an octogenarian population
M Nydegger, A Boltres, K Graves, A Zollinger, CK Hofer
Peripartum cardiomyopathy: a KKH case series
MK Shah, S Leo, CE Ocampo, CF Yim, S Tagore
Levels of serum B12, folic acid and homocysteine in thromboembolic diseases on admission to the Emergency Department
A Bayır, K Uçar Karabulut, A Ak
Deep venous thrombosis Doppler screening in critically ill patients: is it justified?
I Vlachou, G Petrocheilou, E Evodia, M Pappa, L Livieratos, P Myrianthefs, L Gregorakos, G Baltopoulos
Pulmonary embolism in the ICU: clinical and prognostic signification - can we predict mortality?
A Aller, M Mourelo, P Vidal
Model-based cardiovascular monitoring of acute pulmonary embolism in porcine trials
JA Revie, DJ Stevenson, JG Chase, CE Hann, BC Lambermont, A Ghuysen, P Kolh, GM Shaw, T Desaive
Pulmonary embolism diagnostics from the driver function
DJ Stevenson, J Revie, JG Chase, CE Hann, A Le Compte, GM Shaw, B Lambermont, P Kolh, T Desaive
Pulmonary embolism in medical-surgical ICU patients
D Heels-Ansdell, N Zytaruk, M Meade, S Mehta, R Hall, R Zarychanski, M Rocha, W Lim, F Lamontagne, L McIntyre, P Dodek, S Vallance, A Davies, DJ Cooper, DJ Cook
Deep venous thrombosis in ICU patients: exploring the submerged part of the iceberg by an expanded intra-ICU ultrasound surveillance program
A Cecchi, M Boddi, M Ciapetti, F Barbani, M Bonizzoli, J Parodo, L Perretta, G Zagli, E Spinelli, A Peris
Antiembolic stockings and pneumatic compression devices in a medical-surgical thromboprophylaxis trial
N Zytaruk, D Heels-Ansdell, S Vallance, J Marshall, Y Skrobik, DJ Cooper, S Finfer, I Seppelt, M Ostermann, I Qushmaq, M Alsultan, Y Arabi, J Alhashemi, M Al-Hazmi, A Alzem, N Shaikh, Y Mandourah, DJ Cook
Upper extremity thromboses in medical-surgical critically ill patients
N Zytaruk, F Lamontagne, L McIntyre, P Dodek, N Vlahakis, B Lewis, D Schiff, A Moody, M Ostermann, S Padayachee, D Heels-Ansdell, S Vallance, A Davies, JD Cooper, DJ Cook
Real-time ultrasound guidance for internal jugular vein catheterization in neonates: preliminary experience
M Di Nardo, F Stoppa, C Tomasello, C Cecchetti, M Marano, D Perrotta, E Pasotti, N Pirozzi
Is routine ultrasound examination of the gallbladder justified in ICU patients?
E Evodia, I Vlachou, G Petrocheilou, A Gavala, M Pappa, L Livieratos, P Myrianthefs, L Gregorakos, G Baltopoulos
Transthoracic echocardiography performed by intensive care fellows: is minimal focused training enough?
M Almaani, M Alabdrab Alnabi, D Bainbridge, R Taneja
Survey of echocardiography provision and practice in ICUs in the United Kingdom
A Cooke, S Bruemmer-Smith, J McLoughlin, J McCaffrey
Clinical and economic impact of a TEE monitoring system in intensive care
HM Hastings, SL Roth
Usefulness of chest ultrasonography in the management of acute respiratory failure in the emergency room
S Silva, M Dao, C Biendel, B Riu, J Ruiz, B Bataille, J Bedel, M Genestal, O Fourcade
Training in focused echocardiography for intensive care specialists: can delivery meet perceived need?
G McNeill, A Whiteside, A Tridente, D Bryden
Concordance analysis of left ventricular mass by transthoracic echocardiography versus 64-slice multidetector computed tomography
JJ Jimenez, JL Iribarren, J Lacalzada, A Barragan, M Brouard, I Laynez
Coronary artery disease and differential analysis of a valve calcium score by transthoracic echocardiography
JL Iribarren, JJ Jimenez, J Lacalzada, A Barragan, M Brouard, I Laynez
National survey of the use of cardiac output monitoring tool in general adult ICUs in the United Kingdom
O Couppis, S Saha, E Makings
Hemodynamic monitoring in Swiss ICUs: results from a Web-based survey
N Siegenthaler, R Giraud, T Saxer, JA Romand, K Bendjelid
Prediction of cardiac index by body surface temperatures, ScvO2, central venous-arterial CO2 difference and lactate
W Huber, B Haase, B Saugel, V Phillip, C Schultheiss, J Hoellthaler, R Schmid
Impact of hepatic venous oxygen efflux and carotid blood flow on the difference between mixed and central venous oxygen saturation
T Correa, R Kindler, S Brandt, J Gorrasi, T Regueira, H Bracht, F Porta, J Takala, R Pearse, S Mathias Jakob
Goal-directed fluid management based on stroke volume variation and stroke volume optimization during high-risk surgery: a pilot multicentre randomized controlled trial
TW Scheeren, C Wiesenack, H Gerlach, G Marx
Prognosis value of dynamic variation of tissue oxygen saturation during severe cardiogenic shock
P Gaudard, J Eliet, O Attard, P Colson
Prognostic value of the central venous-to-arterial carbon dioxide difference for postoperative complications in high-risk surgical patients
E Robin, E Futier, O Pires, G Lebuffe, B Vallet
Continuous central venous saturation monitoring in critically ill patients
D Chiumello, M Cressoni, A Marino, E Gallazzi, C Mietto, V Berto, M Chierichetti
Femoral venous oxygen saturation is no surrogate for central venous oxygen saturation
A Van der Schors, P Van Beest, H Liefers, L Coenen, R Braam, P Spronk
Predictive value of tissue oxygen saturation upon mortality in Emergency Department patients with sepsis
C Vorwerk, T Coats
Positive central-mixed venous oxygen saturation gradients: high oxygen saturation in the inferior vena cava confirms high splanchnic oxygen extraction
A Reintam Blaser, T Correa, S Djafarzadeh, M Vuda, J Takala, MW Dünser, SM Jakob
Lactate index and survival in hospital-acquired septic shock
S Omar, Mathivha, J Dulhunty, A Lundgren
Effect of minute ventilation on central venous-to-arterial carbon dioxide difference
S Saengngammongkhol, A Wattanathum, A Wongsa
A pulmonary artery catheter-based treatment algorithm changes therapeutic behaviour in septic patients
C Bethlehem, FM Groenwold, MA Kuiper, M Koopmans, EC Boerma
Performance of thermodilution catheters under control and extreme circulatory conditions in a pig model
XX Yang, LA Critchley, F Zhu, Q Tian
Measurement of cardiac output using the transpulmonary thermodilution method in the presence of high extravascular lung water in a pediatric animal model
A Nusmeier, S Vrancken, JG Van der Hoeven, J Lemson
Hemodynamic effects of early endotoxemia on pulse pressure variation during experimental hemorrhagic shock
J Noel-Morgan, DT Fantoni, DA Otsuki, JO Auler Jr
Delta central venous pressure and dynamic indices of preload in postsurgical ICU patients
M Cecconi, F Caliandro, E Barbon, V Elliott, A Dewhurst, A Rhodes
Comparison between pulse pressure variation and conventional parameters as guides to resuscitation in a pig model of acute hemorrhagic shock with endotoxemia
J Noel-Morgan, DT Fantoni, DA Otsuki, JO Auler Jr
Fluid resuscitation based on dynamic predictors of fluid responsiveness: closed loop algorithm versus anesthesiologists
J Rinehart, B Alexander, L Meng, M Cannesson
Prediction of fluid responsiveness in septic shock patients: comparing automated pulse pressure variation by IntelliVue MP monitor and stroke volume variation by FloTrac™/Vigileo™
B Khwannimit, R Bhurayanontachai
Dynamic indices of preload in postcardiac surgery patients by pulse power analysis
E Barbon, F Caliandro, J Kamdar, M Puntis, H Meeran, A Rhodes, A Dewhurst, M Cecconi
Cardiac cycle efficiency as prognostic index in ICUs
A Donati, S Loggi, C Scorcella, MR Lombrano, L Botticelli, MC Melia, A Carsetti, R Domizi, S Tondi, P Pelaia
Evaluation of pulse pressure variation with different inhaled concentrations of desfluorane, sevofluorane and isofluorane in pigs
AH Oshiro, DT Fantoni, DA Otsuki, KT Rosa, JO Auler Jr
E/Ea ratio could not predict fluid response in ICU mechanically ventilated patients
J Cousty, A Mari, P Marty, B Riu, P Sanchez, O Mathe, J Ruiz, S Silva, F Vallée, M Génestal, O Fourcade
Comparison between MostCare and echocardiography for cardiac output estimation in trauma patients
E Falciani, F Franchi, R Silvestri, L Cubattoli, P Mongelli, E Casadei, P Giomarelli, S Scolletta
Comparison of stroke volume changes of LiDCO™plus and Flotrac™ during postoperative hemodynamic optimization
MG Costa, T Cecconet, P Chiarandini, S Buttera, L Pompei, G Della Rocca
A clinical pilot study to evaluate the correlation between pulse wave velocity and cardiac output during elective surgery
D Cain, S Harris
LiDCOrapid and PiCCOplus preload response parameter validation study
P Brass, E Mills, J Latza, J Peters, E Berendes
Comparison of cardiac index: LiDCOrapid and PiCCOplus in the ICU
P Brass, E Mills, J Latza, J Peters, E Berendes
Pressure recording analytical method versus PiCCO in hemodynamic unstable patients
A Donati, S Loggi, A Carsetti, MR Lombrano, L Botticelli, A Valentini, V Fiori, R Domizi, C Scorcella, P Pelaia
Prediction of fluid responsiveness with the LiDCO system
P De Santis, C Marano, F Cavallaro, A Dell'Anna, P De Santis, C Bonarrigo, C Falcone, C Sandroni
Predictors of fluid responsiveness in patients with acute liver failure
VK Audimoolam, M McPhail, W Bernal, C Willars, JA Wendon, G Auzinger
Functional haemodynamic monitoring: the relative merits of SVV, SPV and PPV as measured by the LiDCOrapid in predicting fluid responsiveness in high-risk surgical patients
C Willars, A Dada, D Green
Pressure recording analytical method for cardiac output monitoring in children with congenital heart disease
Z Ricci
Accuracy of stroke volume variation as a predictor of volume responsiveness in patients with raised intra-abdominal pressure
WO Bauer, M Cecconi, A Rhodes, W Bernal, J Wendon, G Auzinger
Perfusion index as a predictor for central hypovolemia in humans
A Lima, M Van Genderen, E Klijn, S Bartels, J Van Bommel, J Bakker
Carotid blood flow is correlated with cardiac output but not with arterial blood pressure in porcine fecal peritonitis
T Correa, A Reintam Blaser, J Takala, S Djafarzadeh, M Vuda, M Dünser, S Mathias Jakob
Afterload-related cardiac performance: a hemodynamic parameter with prognostic relevance in patients with sepsis in the Emergency Department
J Wilhelm, S Hettwer, M Schürmann, S Bagger, F Gerhardt, S Mundt, S Muschick, J Zimmermann, H Ebelt, K Werdan
Evaluation of a continuous non-invasive arterial blood pressure monitoring device in comparison with an arterial blood pressure measurement in the ICU
K Smolle, M Schmid
Brachial cuff measurements for fluid responsiveness prediction in the critically ill
K Lakhal, S Ehrmann, D Benzekri-Lefèvre, I Runge, A Legras, E Mercier, PF Dequin, M Wolff, B Régnier, T Boulain
Are the calf and the thigh reliable alternatives to the arm for cuff non-invasive measurements of blood pressure?
K Lakhal, C Macq, S Ehrmann, T Boulain, X Capdevila
Validation of non-invasive hemodynamic monitoring with Nexfin in critically ill patients
K Van de Vijver, A Verstraeten, C Gillebert, U Maniewski, M Gabrovska, D Viskens, N Van Regenmortel, I De laet, K Schoonheydt, H Dits, M Malbrain
Pleth Variability Index predicts fluid responsiveness in critically ill patients
H Nanadoumgar, TL Loupec, DF Frasca, FP Petitpas, LL Laksiri, DB Baudouin, OM Mimoz
Dynamics of peripheral perfusion parameters in elective coronary artery bypass graft patients
M Van Genderen, J Boszhuizen, A Pinto Lima, D Gommers, J Bakker, J Van Bommel
Maintenance of arterial catheters with heparin: should we continue?
N Catorze, S Teixeira, J Cabrita, J Carreto, V Vieira, S Gonçalves, A Frade, J Martins
Validation of continuous intragastric pressure measurement and correlation with intramucosal pH in a pig model
M Malbrain, I De laet, L Luis, L Correa, M Garcia, G Castellanos
End-tidal carbon dioxide levels predict cardiac arrest
H Manyam, P Thiagarajah, G Patel, R French, M Balaan
NT-proBNP and troponin I in acute liver failure: do they predict cardiac dysfunction?
M Mcphail, VK Audimoolam, W Bernal, C Willars, R Sherwood, J Wendon, G Auzinger
Endothelial glycocalyx disruption after cardiac surgery in infants
V Sheward, S Tibby, H Bangalore, A Durward, I Murdoch
Microcirculatory changes during hyperoxia in a porcine model of ruptured abdominal aneurysm
I Cundrle Jr, V Sramek, P Suk, J Hruda, J Krbusik, M Helan, M Vlasin, M Matejovic, M Pavlik
Impact of synthetic colloids on organ function in patients with severe sepsis
O Bayer, M Kohl, B Kabisch, N Riedemann, Y Sakr, C Hartog, K Reinhart
Intraoperative effectiveness of crystalloid and colloid volume substitution in patients undergoing elective major urological surgery by maintenance of the cardiac index within normal range
P Szturz, R Kula, J Maca, J Tichy, J Jahoda
Dilution with three different solutions: plasmatic effects and quantity and quality of urinary output
T Langer, E Carlesso, A Protti, M Monti, L Zani, G Iapichino, B Comini, D Andreis, C Sparacino, D Dondossola, L Gattinoni
Efficacy and safety of 10% HES 130/0.4 versus 10% HES 200/0.5 for plasma volume expansion in cardiac surgery patients
C Ertmer, H Van Aken, H Wulf, P Friederich, C Mahl, F Bepperling, M Westphal, W Gogarten
Nicorandil versus nitroglycerin: a pilot study
V Singh, S Momin, B Shah
Dopamine versus norepinephrine in septic shock: a meta-analysis
S Shenoy, A Ganesh, A Rishi, V Doshi, S Lankala, J Molnar, S Kogilwaimath
Comparative evaluation of therapeutic interventions during hemorrhagic shock
D Fantoni, DA Otsuki, AR Martins, JA Filho, E Andrades, E Chaib, FA Voorwald
Effects of vasopressinergic V1 receptor agonists on sublingual microcirculatory blood flow in patients with catecholamine-dependent septic shock
A Morelli, A Donati, C Ertmer, S Rehberg, A Orecchioni, A Di Russo, G Citterio, MR Lombrano, L Botticelli, A Valentini, P Pelaia, P Pietropaoli, M Westphal
Vasopressin for the treatment of vasodilatory shock: an ESICM systematic review and a meta-analysis
A Polito, E Parisini, Z Ricci, S Picardo, D Annne
Effects of early versus delayed terlipressin infusion on hemodynamics and catecholamine requirements in ovine septic shock
TG Kampmeier, M Westphal, S Rehberg, A Morelli, M Lange, H Van Aken, C Ertmer
Levosimendan in trauma patients with acute cardiac failure
AN Afonin, N Karpun
Treatment of calcium channel blocker overdose with levosimendan
A Sencan, T Adanır, G Terzi, A Atay, N Karahan
Effect of different antioxidants in ischemia-reperfusion syndrome
W Hoyos, L Alfaro, B Garcia-Prieto, G Lopez, P Flores
Searching for mechanisms that matter in septic acute kidney injury: an experimental study
J Benes, J Chvojka, R Sykora, J Radej, A Krouzecky, I Novak, M Matejovic
Raised serum creatinine at admission to critical care is independently associated with mortality in patients with decompensated alcoholic liver disease
A Whiteside, P Whiting
Contrast-induced nephropathy in ITU patients: outcomes of a university hospital re-audit
K Lam, T Chan, R Lowsby, J Walker
Evaluation of acute kidney injury with pediatric-modified RIFLE criteria after pediatric cardiac surgery
P Zeyneloglu, A Pirat, E Baskin, A Camkiran, C Araz, M Ozkan, N Bayraktar, G Arslan
Acute kidney injury after coronary artery bypass grafting surgery
P Zeyneloglu, A Pirat, N Veziroglu, A Sezgin, G Arslan
Increased severity of acute kidney injury does not increase long-term mortality
MB Pereira, DMT Zanetta, RCRM Abdulkader
Any level of acute kidney injury may be associated with mortality in critically ill patients
AP Rucks, AF Meregalli, DA Becker, JM Andrade, G Friedman
A comparison of four methods to define timing of acute kidney injury
KA Wlodzimirow, A Abu-Hanna, C Bouman
Validation of the AKIN criteria definition using high-resolution ICU data from the MIMIC-II database
T Mandelbaum, DJ Scott, J Lee, RG Mark, MD Howell, A Malhotra, D Talmor
Urine biomarkers for gentamicin-induced acute kidney injury in the neonatal ICU
D Jansen, S Heemskerk, L Koster-Kamphuis, TP Bouw, AF Heijst, P Pickkers
Neutrophil gelatinase-associated lipocalin in ICU patients developing oliguria
A Roman, M Suball, V Piersoel, T El Mahi, C Hanicq, E Stevens
Use of Doppler ultrasound renal resistive index and neutrophil gelatinase-associated lipocalin in prediction of acute kidney injury in patients with septic shock
CW Ngai, MF Lam, SH Lo, CW Cheung, WM Chan
Removal of drug delivered via a central venous catheter by a dual-lumen haemodiafiltration catheter inserted at the same site: a quantitative flow model
R Kam, JM Mari, TJ Wigmore
Effect of total parenteral nutrition on the duration of haemofilter circuit
S Saha, P Shah, J Gibbs, J Collins
Effects of ultrafiltration on systemic hemodynamics and microcirculatory perfusion in patients with end-stage kidney disease
E Klijn, M Van Genderen, M Betjes, J Bakker, J Van Bommel
Best prediction for need of dialysis following cardiac surgery is obtained with the Thakar model
HD Kiers, MC Schoenmakers, HA Van Swieten, JG Van der Hoeven, S Heemskerk, P Pickkers
Hypercalcemia during renal replacement therapy after liver transplantation
J Matsumi, H Morimatsu, K Morita
In vitro evaluation of HMGB1 removal with various membranes for continuous hemofiltration
M Yumoto, O Nishida, K Moriyama, Y Shimomura, T Nakamura, N Kuriyama, Y Hara, S Yamada, T Miyasho
Sustained high-efficiency daily diafiltration using a cytokine-adsorbing membrane in the treatment of patients with severe sepsis
O Nishida, T Nakamura, N Kuriyama, Y Hara, K Moriyama, M Yumoto, Y Shimomura
Model-based cardiovascular monitoring of large pore hemofiltration during endotoxic shock in pigs
JA Revie, DJ Stevenson, JG Chase, CE Hann, GM Shaw, A Le Compte, BC Lambermont, A Ghuysen, P Kolh, T Desaive
Different effect of CVVHDF and coupled plasma filtration and adsorption on IL-6 and procalcitonin in sepsis
F Turani, M Falco, R Barchetta, F Candidi, A Marinelli, C Di Corato
Effectiveness of continuous venovenous hemodiafiltration using a polymethylmethacrylate membrane hemofilter judging from a multiplex suspension array system in septic shock patients
Y Sakamoto, T Miyasho, N Kutsukata, T Ito, T Iwamura, A Nakashima, M Yahata, K Mashiko, H Yokota, T Obata
Catecholamine index is a simple and useful marker for bacteremic patients treated by polymyxin B hemoperfusion therapy
Y Isa, N Harayama, H Arai, T Shinjou, K Nagata, M Ueki, S Nihei, K Aibara, M Kamochi
Re-evaluation of direct hemoperfusion with polymyxin-B immobilized fiber for severe sepsis and septic shock
SM Matsuo, TI Ikeda, KI Ikeda
Extended duration of direct hemoperfusion with polymyxin B-immobilized fiber column improves hemodynamics in patients with septic shock
C Yamashita, Y Takasaki
Use of activated clotting time to monitor anticoagulation in patients receiving unfractionated heparin on renal replacement therapy
A Bidwai, R Sundaram
Single-dose application of antithrombin III as alternative anticoagulation during extracorporeal therapy in critically ill patients with advanced liver cirrhosis: a retrospective data analysis
R Brunner, C Madl, W Druml, U Holzinger
Safety of drotrecogin alfa (activated) treatment in patients with severe sepsis on renal replacement therapy without additional anticoagulation
L Mirea, I Luca Vasiliu, R Ungureanu, A Balanescu, I Grintescu
Association between type of anticoagulation and blood transfusion requirements during renal replacement therapy in the ICU
A Iyer, J Ewer, L Tovey, H Dickie, M Ostermann
Economic argument for citrate haemofiltration
J Patterson, D Laba, M Blunt
Multicenter prospective observational study on safety and efficacy of regional citrate anticoagulation in CVVHD in the presence of liver failure: the Liver Citrate Anticoagulation Threshold Study (L-CAT)
T Slowinski, S Morgera, M Joannidis, T Henneberg, R Stocker, E Helset, K Andersen, M Wehner, J Kozik-Jaromin, S Brett, J Hasslacher, JF Stover, H Peters, HH Neumayer, D Kindgen-Milles
Regional citrate anticoagulation in high-volume continuous venovenous hemodialysis
R Kalb, J Ammann, T Slowinski, S Morgera, D Kindgen-Milles
Systemic citrate load during continuous renal replacement therapy is not negligible and can be predicted using indirect methods
M Zakharchenko, M Balik, M Otahal, J Hruby, J Vavrova, A Jabor
Use of 2-hourly creatinine clearance to inform cessation of renal replacement therapy
O Solymos, S Frohlich, N Conlon
NT-proBNP, troponin I and troponin T are elevated in ARDS patients without structural heart disease: a single initial reading of cardiac markers is not different from serial daily readings
Y Nassar, D Monsef, S Abdelshafy, G Hamed
Comparison of three different multi-analyte point-of-care devices during clinical routine on a medical ICU
V Stadlbauer, S Wallner, T Stojakovic, KH Smolle
Appropriate regulation of routine laboratory testing can reduce the costs associated with patient stay in intensive care
K Goddard, SJ Austin
Contribution of red blood cells to the compensation for hypocapnic alkalosis through plasmatic strong ion difference variations
T Langer, L Zani, E Carlesso, A Protti, P Caironi, M Chierichetti, ML Caspani, L Gattinoni
Interactive visual analysis of a large ICU database: a novel approach to data analysis
H Gan, K Matkovic, A Ammer, W Purgathofer, D Bennett, M Terblanche
Base excess can be misleading in acute respiratory acidosis
S Kocsi, K Kiss, B Szerdahelyi, M Demeter, Z Molnar
Prescription and clinical impact of chest radiographs in 104 French ICUs: the RadioDay Study
MS Serveaux-Delous, K Lakhal, X Capdevila, JY Lefrant, S Jaber
Intraosseous blood aspirates analysed by a portable cartridge-based device
G Strandberg, A Larsson, M Lipcsey, M Eriksson
Capnography activation is improved by better ventilator interface ergonomics
E Hodge, M Blunt, P Young
Impact of cardiac arrest duration on extravascular lung water and pulmonary vascular permeability in patients with postcardiac arrest syndrome: a prospective observational study
T Tagami, R Tosa, M Omura, J Hagiwara, N Kido, H Hirama, H Yokota
Ultrasonography is a valuable non-invasive tool for determining extravascular lung water in severe sepsis
M Kok, H Endeman
Indexing extravascular lung water to predicted body weight increases the correlation with lung injury score in patients with acute lung injury/acute respiratory distress syndrome: a prospective, multicenter study conducted in a Japanese population
H Fukushima, T Seki, Y Urizono, M Hata, K Nishio, K Okuchi
Feasibility of continuous exhaled breath analysis in intubated and mechanically ventilated critically ill patients
LD Bos, PJ Sterk, MJ Schultz
Pattern of cytokines and chemokines in exhaled breath condensate is related to the characteristics of mechanical ventilation
I Van Walree, A Van Houte, G Rijkers, H Van Velzen-Blad, H Endeman
Divergent changes in regional pulmonary filling characteristics during endotoxin-induced acute lung injury in pigs
A Aneman, S Sondergaard, A Fagerberg, H Einarsson
Electrical impedance tomography to monitor regional tidal ventilation at different pressure support levels
T Mauri, G Bellani, A Confalonieri, P Tagliabue, M Bombino, N Patroniti, G Foti, A Pesenti
Endotracheal cuff pressure: role of tracheal size and cuff volume
PL Lichtenthal, UB Borg
A survey of healthcare professionals' knowledge of emergency oxygen use in adult patients
A Hartopp, K Horner, C Botfield
Weaning from NIV: how rapidly can we go?
J Chico, L Sayagues, R Casado, M Muñoz, L Lage, S Vara, V Gomez, C Vara
Factors associated with non-invasive ventilation response on the first day of therapy in patients with hypercapnic respiratory failure
G Gürsel, M Aydoğdu, S Taşyürek, G Gülbaş, S Özkaya, S Nazik, A Demir
Formal airway assessment prior to emergency tracheal intubation: a regional survey of usual practice
A Karmali, S Saha, P Patel
Urgent orotracheal intubation in critically ill patients
M Hernández Bernal, JJ Manzanares Gomez, C Soriano Cuesta, A Agrifoglio Rotaeche, J Figueira, J López, M Jimenez Lendinez
Propofol is the induction agent of choice for urgent intubations with UK physicians
KD Rooney, R Jackson, A Binks, A Jacques, RT IC-Severn
Frequency and significance of post-intubation hypotension during emergency airway management
A Heffner, D Swords, J Kline, A Jones
Clinical experiences with a new endobronchial blocking device: the EZ-Blocker
T Végh, A Enyedi, I Takács, J Kollár, B Fülesdi
Rohrer's constant, k2, as a factor for determining endotracheal tube obstruction
AG Flevari, N Maniatis, E Dimitriadou, M Theodorakopoulou, E Paramythiotou, N Christoforidis, A Kaziani, D Koukios, F Drakopanagiotakis, A Armaganidis
Acute desaturation in intubated patients
P Myrianthefs, C Kouka, E Giannelou, E Evodia, G Baltopoulos
Continuous control of tracheal cuff pressure and microaspiration of gastric contents: a randomized controlled study
S Nseir, F Zerimech, C Fournier, R Lubret, P Ramon, A Durocher, M Balduyck
Outcome of tracheostomy timing on critically ill adult patients undergoing mechanical ventilation: a retrospective observational study
A Dhrampal, D Pearson, N Berry
Duration of mechanical ventilation on the result of diaphragmatic function in weaning
HB Qiu, W Guo, Y Yang
Hand-grip test is a good predictor of extubation success in adult ICU patients
D De Bels, J Devriendt, P Gottignies, D Chochrad, S Theunissen, T Snoeck, C Balestra, U Pilard, S Roques
Use of NT-proBNP in weaning from mechanical ventilation
A Martini, B Benedetti, N Menestrina, E Polati, E Bresadola, L Gottin
Efficacy of implementation strategies of an evidenced-based awakening and breathing protocol
O Almuslim, M Rezk, N Hassan
Can we predict left ventricular dysfunction-induced weaning failure? Invasive and echocardiographic evaluation
A Abdelbary, W Ayoub, Y Nassar, K Hussein
High-flow oxygen therapy through nasal cannulae versus low-flow oxygen therapy via Venturi mask after extubation in adult, critically ill patients
F Antonicelli, A Cataldo, R Festa, F Idone, A Moccaldo, M Antonelli, SM Maggiore
Post-intubation tracheal stenosis in the ICU: diagnosis and treatment
N Makhoul, E Altman, S Croitoru, S Ivry, A Gurevich, S Krimerman, M Croitoru
Can extubation failure be related to high unit activity?
I Keith, R Sundaram, KD Rooney
Decannulation: in the ICU or in the ward? Does it really matter?
O Milercy, J López, J Figueira, J Manzanares, M Hernández
Assessment of the impact of unplanned extubation on ICU patient outcome
E Bastos de Moura, J Aires de Araújo Neto, M De Oliveira Maia, F Beserra Lima, R Fernandes Bomfim
Outcome and complications in infants with respiratory failure: venovenous two-site versus double-lumen ECMO
M Hermon, G Mostafa, J Golej, G Burda, R Vargha, G Trittenwein
Weaning-induced alterations in cardiac function: invasive and echocardiographic assessment
A Abdelbary, W Ayoub, Y Nassar, K Hussein
Impact of open lung ventilation on right ventricular outflow impedance assessed by transoesophageal echocardiography
S Salah, H El-Akabawy
Lung sound amplitude measured by vibration response imaging is influenced by the presence of secretions
S Lev, AS Stern-Cohen, MS Shapiro, JC Cohen, YG Glickman, PS Singer
Continuous elevation of lung sound amplitudes, recorded at fixed flow rate, may indicate an increase in lung water content
S Lev, P Singer, K Robinson, K Hojnowski, L Wolloch, L Gatto, GF Nieman
Impact of normocapnic and permissive hypercapnic one-lung ventilation on arterial oxygenation
T Végh, Z Szabó-Maák, S Szatmári, J Hallay, I László, I Takács, B Fülesdi
Titration of analgosedation with neurally adjusted ventilatory assist in the ICU
MJ Sucre, A De Nicola
Early prognostic indices for weaning after long-term mechanical ventilation
A Temelkov, R Marinova, M Lazarov
Alveolar morphology depends on ventilator settings: lessons from in vivo alveolar microscopy under static and dynamic conditions
D Schwenninger, S Schumann, J Guttmann
Ventilatory ratio: validation in an ex vivo model and analysis in ARDS/ALI patients
P Sinha, K Corrie, A Bersten, JG Hardman, N Soni
Therapy with recombinant human antithrombin, heparin and tissue plasminogen activator improves survival and reduces ventilation days in a long-term ovine model of cutaneous burn and smoke inhalation injury
S Asmussen, Y Yamamoto, DL Traber, H Ito, R Cox, H Hawkins, LD Traber, D Herndon, P Enkhbaatar
Hypercapnic acidosis transiently weakens hypoxic pulmonary vasoconstriction in anesthetized pigs, without affecting the endogenous pulmonary nitric oxide production
MC Nilsson, A Larsson, K Hambraeus-Jonzon
Stenotrophomonas maltophilia in the respiratory tract of medical ICU patients
B Saugel, K Eschermann, R Schmid, W Huber
Hospital-acquired pneumonia is associated with deficient γc-cytokine gene expression
M White, R McManus, T Ryan
Clinical aspects and predictors of mortality of Pseudomonas aeruginosa pneumonia in a cohort of critically ill patients
G De Pascale, F Antonicelli, R Maviglia, A Cataldo, R Festa, F Idone, EM Trecarichi, MA Pennisi, M Tumbarello, M Antonelli
Safety and efficacy of intratracheal DNase with physiotherapy in severe status asthmaticus
A Nyman, K Puppala, S Colthurst, S Parsons, S Tibby, I Murdoch, A Durward
Relation between mortality rate, duration of hospitalization and levels of TNFα, IL-6 and catalase at admission of cases to the emergency department with COPD attack
A Bayır, P Büyükünaldı, A Kıyıcı, A Ak, F Kara
Induced hypothermia is protective in a rat model of pneumococcal pneumonia
C Beurskens, H Aslami, M Kuipers, M Schultz, N Juffermans
Incidence of and risk factors for nonrespiratory acute organ failure in ICU patients receiving respiratory support: a pilot international cohort study
M Terblanche, A Smith, E Recchia, M Harward, L Gilfeather, D McAuley
Pharmacological randomized controlled trials in acute respiratory distress syndrome mortality
C Santacruz, E Carrasco, J Wardini Dantas do Amaral
Positive end-expiratory pressure improves oxygenation inducing ventral-to-dorsal tidal ventilation redistribution: an electrical impedance tomography study
T Mauri, G Bellani, A Pradella, A Grassi, P Tagliabue, M Bombino, N Patroniti, G Foti, A Pesenti
Neurally adjusted ventilatory assist reduces asynchrony and patient effort in severe acute respiratory distress syndrome patients undergoing extracorporeal membrane oxygenation
T Mauri, G Bellani, A Confalonieri, F Magni, G Grasselli, N Patroniti, A Pesenti
Danger signal uric acid is involved in ventilator-induced lung injury pathogenesis
M Kuipers, H Aslami, T Van der Poll, M Schultz, C Wieland
High-frequency oscillatory ventilation in adults: experience in Chile
SU Ugarte, CR Rojas, C Herrera
Stress-strain relationship in pulmonary cells under bidirectional stretch application
K Gamerdinger, S Schumann, F Wernet, E Faehnrich, M Schneider, J Guttmann
Optimal positive end-expiratory pressure in mechanically ventilated patients: a clinical study
A Sundaresan, JG Chase, CE Hann, GM Shaw
Flow-balanced expiration reduces oedema formation in a porcine oleic acid lung injury model
S Schumann, U Goebel, J Haberstroh, M Schneider, HJ Priebe, M Lichtwarck-Aschoff, J Guttmann
Positive changes in the continuous desaturation index during mechanical ventilation are associated with mortality due to acute respiratory failure
G Vazquez de Anda, S Larraza, J Talavera, L De la Cruz Avila, H Lopez, D Rodriguez
Strain threshold for ventilator-induced lung injury
A Santini, A Protti, M Cressoni, T Langer, D Febres, G Conte, L Lombardi, M Lattuada, P Taccone, L Gattinoni
Do athletes require a higher tidal volume? An approach using predicted versus measured PFTs
P Myrianthefs, G Baltopoulos
Potential reduction of ventilator-associated pneumonia by a novel peristaltic feeding tube: initial evaluation of safety and efficacy in a pig model and humans
Y Avitzur, L Dayan, O Pintel, M Dayan, S McClave, P Singer
Respiratory variability in mechanically ventilated patients
T Desaive, L Piquilloud, K Moorhead, J Roeseler, JG Chase, E Bialais, PF Laterre, P Jolliet, T Sottiaux, D Tassaux, B Lambermont
Suspended animation-inducer hydrogen sulphide protects against organ injury during endotoxemia, but aggravates systemic inflammation
H Aslami, C Beurskens, F De Beer, M Kuipers, M Schultz, N Juffermans
Dead space fraction indicates the titration of optimal positive end-expiratory pressure after recruitment in acute respiratory distress syndrome
Y Yang, J Chen, H Qiu
Dynamic distribution of conventional dendritic cells in the lung, blood and spleen from the early phase of sepsis-induced acute lung injury
J Liu, H Qiu
A radiological visual scale to predict the potentially recruitable lung in ALI/ARDS patients
D Chiumello, M Cressoni, A Marino, E Gallazzi, M Brioni, MC Andrisani, M Lazzerini, P Biondetti
Interactions of nebulized heparin with intravenous antithrombin for combined therapy of acute lung injury
S Rehberg, L Sousse, Y Yamamoto, LD Traber, DL Traber, P Enkhbaatar
Thrombopoietin may enhance ventilator-induced lung injury
LD Del Sorbo, V Fanelli, G Muraca, EL Martin, L Lutri, A Costamagna, B Assenzio, E Lupia, G Montrucchio, VM Ranieri
Indoleamine-2,3-dioxygenase activity induces neutrophil apoptosis
K Van der Sluijs, R Singh, A Dijkhuis, M Snoek, R Lutter
Defining sepsis in the ICU: a sensitivity analysis
P Klein Klouwenberg, OL Cremer
Analysis of nosocomial bacteremia in an ICU during 16 months
L Cachafeiro, C Soriano, J Figueira, J Manzanares, J Camacho, M Jimenez Lendinez
Delayed ICU admission with community-acquired severe sepsis greatly increases mortality and resource use
A Shorr, Y Choe, W Linde-Zwirble
Septic shock in a cohort of patients from the northeast of France: a preliminary epidemiological study, EPISS group
J Quenot, A Pavon, C Binquet, F Kara, O Martinet, JC Navellou, D Barraud, J Cousson, JF Poussel
Long-term effects of an in-hospital program on sepsis management in the ICU
E Ferrari, G Serafini, D Trevisan, L Donno, L Rinaldi, M Girardis
Extending the classification of healthcare-associated bloodstream infection to other main foci: respiratory, urinary and intra-abdominal
C Cardoso, O Ribeiro, I Aragão, A Costa-Pereira, A Sarmento
Healthcare-associated infection: do doctors recognize this group of patients?
T Cardoso, O Ribeiro, I Aragão, A Costa-Pereira, A Sarmento
Sustainability of an antimicrobial stewardship program in a community hospital ICU at 3 months post implementation
K Walker, J Sauve, J Powis, V Leung, S Gill
Attention to electronic prescription process improves time to first-dose antibiotics in patients on the ICU
R Wan, D Gonzalez Bermejo, S Moore, C Whiteley, C Mckenzie, A Jones
An audit of antibiotic dosing according to renal function or renal replacement therapy in critical care
KD Donnelly, KD Smith, JJ Coleman, D Westwood, AN Billington
De-escalation of antimicrobial therapy in Gram-negative sepsis: easier said than done?
L Phee, N Gordon, M Hornsey, D Wareham
Impact of the adequacy of antibiotic therapy on the outcome of ventilator-associated pneumonia
J Goncalves-Pereira, T Sequeira, B Moya, T Cardoso, N Catorze
Aetiology of pneumonia in the ICU: the need for early Gram-negative cover
A Khanna, H Al-shather, M Chawla, R Gibbs
Respiratory failure in cancer patients with influenza A (H1N1) is associated with poor prognosis
E Snyder, M Cardenas-Turanzas, C Perego, R Erfe, RC Chemaly, KP Price, JL Nates
Hemodynamic and echocardiographic characteristics in severe novel influenza A (H1N1) pneumonia
P Theerawit, Y Sutherasan, T Hongpanat, C Kiatboonsri, S Kiatboonsri
Gram-positive nosocomial infections in a general ICU: emerging new clues
S Milanov, G Georgiev, V Todorova, M Milanov
Prevalence of Gram-negative bacilli resistance in adult critically ill patients at admission screening
D Kotwinski, R Batra, T Olga, J Edgeworth, D Wyncoll, M Shankar-Hari
Risk factors to bloodstream infection due multidrug-resistant Results Acinetobacter baumanni in colonized patients in the ICU
R Passos, S Ultchak, P Mota, AV Mendes, M Souza, RH Oliveira, PB Batista
Blood cultures at central line insertion: a comparison with peripheral venipuncture
S Stohl, S Benenson, S Sviri, C Block, C Sprung, P Levin
Higher incidence of catheter-related bloodstream infection in femoral venous access than in subclavian venous access in the presence of tracheostomy
L Lorente, S Palmero, JJ Jiménez, I Roca, C Naranjo, J Castedo, S Huidobro, L Lorenzo, JL Iribarren, ML Mora
Polyhexanide anti-infective coating of central venous catheters in prevention of catheter colonization and bloodstream infection: Study HC-G-H-0507
I Krikava, M Kolar, B Garajova, T Balik, A Sevcikova, J Pachl, P Sevcik, R Trubac
Central line change in potential catheter-related bloodstream infection: target for intervention to reduce harm
R Davies, M Lowings, AT Jones, CJ Langrish
Clostridium difficile-associated diarrhoea in a tertiary referral neurocritical care centre
S Tripathy, C Kataria, PV Nair
A creep in the vancomycin minimum inhibitory concentration for Staphylococcus aureus in a tertiary care hospital in India
A Bhakta, M Bhattacharyya, S Todi
Prognostic impact of imported and newly-isolated methicillin-resistant Staphylococcus aureus in the ICU
S Ohshimo, K Ota, T Tamura, Y Kida, J Itai, K Suzuki, T Inagawa, Y Torikoshi, T Otani, T Sadamori, R Tsumura, Y Iwasaki, N Hirohashi, K Tanigawa
Increased mortality associated with methicillin-resistant Staphylococcus aureus infection in the ICU: results from the EPIC II study
H Hanberger, S Walther
Intrathecal (intraventricular) polymyxin B in the treatment of patients with meningoencephalitis by Acinetobacter baumanii and Pseudomonas aeruginosa
SK Macedo, IP Gonçalves, GVdO Bispo, LRd Almeida, LBdA Brito
Effects of tigecycline and doxycycline in porcine endotoxemia
M Von Seth, J Sjölin, A Larsson, M Eriksson, M Lipcsey
Blood transfusions: an independent risk factor for the development of Candida infections in critically ill surgical patients
G Burghi, G Ortiz, H Bagnulo
Demographic and outcome differences in ICU patients with proven invasive candidiasis, possible invasive candidiasis and probable candida colonization: analysis of the EPIC II study population
D Kett, G Dimopoulos, E Azoulay, P Echeverria, JL Vincent
Anidulafungin for candidemia/invasive candidiasis in non-neutropenic ICU patients
M Ruhnke, J Paiva, W Meersseman, J Pachl, I Grigoras, G Sganga, F Menichetti, P Montravers, G Auzinger, G Dimopoulos, M Borges Sá, P Miller, T Marček, M Kantecki
Pharmacokinetics of micafungin in patients with severe burn injuries
J Sasaki, S Kishino, S Hori, N Aikawa
Invasive aspergillosis in critically ill hematology patients: outcomes and prognostic factors associated with mortality
G Burghi, V Lemiale, E Azoulay
Effects of endotoxin on pacemaker funny current in HEK 293 cells
VP Papaioannou, A Van Ginneken, AV Verkerk, JB De Bakker
Influence of an immunoglobulin-enriched (IgG, IgA, IgM) solution on activation and immunomodulatory functions of peripheral blood mononuclear cells in a LPS second-hit model
C Duerr, A De Martin, M Sachet, T Konrad, S Baumann, A Spittler
Lipopolysaccharide induces mitochondrial dysfunction in rat cardiac microvascular endothelial cells
M Vuda, M Chiusa, SM Jakob, J Takala, C Zuppinger, S Djafarzadeh
Monocyte subset recruitment to the peritoneum following abdominal surgical incision in mice
N Bunker, KP O'Dea, JM Handy, M Takata
Influence of body mass index on the innate immune response during human endotoxemia
R Van der Pluijm
Effect of bacterial load versus duration of exposure to bacteria on plasma TNFα concentrations in porcine fecal peritonitis
T Correa, L Brander, S Djafarzadeh, R Schröder, J Takala, A Reintam Blaser, M Vuda, S Mathias Jakob
Does leukocyte apoptosis play any role in the pathogenesis of experimental pancreatitis?
D Zotos, T Adamis, A Pistiki, K Louis, E Giamarellos-Bourboulis
IFNγ prolongs survival in experimental Escherichia coli pyelonephritis: implications for favorable phagocytosis
M Katsaris, T Adamis, M Georgitsi, A Pistiki, M Chrisofos, E Giamarellos-Bourboulis
Regulation of endothelial function by coagulation proteases in sepsis
JN McLaughlin, R Ramachandran, AM Kaynar, SD Shapiro, DC Angus, AB Malik
Effect of HO-3089 PARP inhibitor on inflammatory response
M Nemeth, T Leiner, K Tanczos, A Mikor, Z Molnar, K Kovacs
Inflammatory mediator modulation with specific or selective adsorbents
A Schildberger, T Buchacher, V Weber, D Falkenhagen
Honokiol attenuates the severity of acute pancreatitis-associated lung injury by acceleration of acinar cell apoptosis
T Weng
Impact of modulation of the endocannabinoid system on the intestinal microcirculation in experimental sepsis
C Lehmann, R Kuschnereit, I Kiister, J Zhou, S Whynot, O Hung, R Shukla, D Henzler, V Cerny, D Pavlovic, M Kelly
Desmopressin improves intestinal functional capillary density and decreases leucocyte activation in experimental endotoxemia in the rat
L Wagner, I Drzymulski, D Pavlovic, D Henzlers, M Wendt, C Lehmann
Hypoxic NO-donor nitrite protects sGC-dependently against morbidity and mortality associated with sterile inflammatory shock in mice
A Cauwels, B Vandendriessche, E Rogge, S Shiva, P Brouckaert
Interplay between the innate immune response and heart rate variability in healthy human volunteers
M Kox, BP Ramakers, JC Pompe, JG Van der Hoeven, CW Hoedemaekers, P Pickkers
Dysregulation of immune monocyte responses during sepsis
D Fiume, G Caiazza, V Tsekeuli, A Sinistro, C Almerighi, F Calo'-Carducci, E Baffari, A Bergamini, S Natoli, F Leonardis
Different correlations between lymphocyte subsets from patients with intra-abdominal sepsis and pneumonia-derived sepsis
TS Skirecki, UZ Zielińska-Borkowska, MZ Złotorowicz, JK Kawiak, GH Hoser
AZD9773 is a novel and potent anti-TNFα polyclonal ovine immune Fab
P Newham, P Ceuppens, G Davies, J Growcott
Preclinical pharmacodynamics and safety profiling of AZD9773: a novel anti-TNFα polyclonal immune ovine Fab similar to D-CytoFab
P Newham, J Yates, S Das, J Kemp, J Young, P Ceuppens, F Brennan, R Knight, J Growcott
Safety and tolerability of an ovine-derived polyclonal anti-TNFα Fab fragment (AZD9773) in patients with severe sepsis
P Morris, B Zeno, A Bernard, X Huang, S Simonson, G Bernard
Evaluation of eritoran tetrasodium (E5564), a TLR4 antagonist, on the QTc interval in healthy subjects
CF Nagy, M Lynn, J Gogate
Safety, pharmacokinetics, and pharmacodynamics of 4-hour intravenous infusion of eritoran tetrasodium in healthy Japanese and Caucasian males
Y Okubo, N Aikawa, M Lynn, DP Rossignol, YN Wong, E Schuck, Y Kitahara, T Nakano, O Sivak, KM Wasan, C Nagy
Dipyridamole modulates the innate immune response during human endotoxemia
B Ramakers, NP Riksen, TH Stal, S Heemskerk, P Van den Broek, JG Van der Hoeven, P Smits, P Pickkers
Use of statins in community-acquired pneumonia in intensive care settings: is there a survival advantage?
A Khanna, R Gibbs, S Webster, H Al-shather
Atorvastatin for preventing the progression of sepsis to severe sepsis (ASEPSIS Trial): a randomised, double-blind, placebo-controlled trial (ISRCTN64637517)
JM Patel, C Snaith, D Thickett, L Linhortova, T Melody, P Hawkey, T Barnett, A Jones, T Hong, G Perkins, M Cooke, F Gao-Smith
Kinetics of immunoglobulins in septic shock patients
C Siqueira, C David, C David
Whole blood lactate kinetics in patients undergoing quantitative resuscitation for septic shock
MA Puskarich, S Trzeciak, N Shaprio, A Heffner, JA Kline, AE Jones
Plasma DNA concentration as an early predictor of outcome in critically ill septic patients
H El-Akabawy, W Radwan, S Gengeehy, A Rezk, A Sisi
C-reactive protein as an early marker of sepsis resolution: results from the Portuguese Community-acquired Sepsis Study (SACiUCI study)
P Povoa, A Teixeira-Pinto, A Carneiro
Effect of including procalcitonin and C-reactive protein in the Mortality in Emergency Department Sepsis risk prediction model
C Lee, J Liu, S Chen, S Chen
Prognostic value of routinely assessed serum biomarkers in septic shock
E Lafuente, E Viegas, E Filipe, E Tomas, M Fernandes, J Gomes da Silva, F Santos, F Moura, R Lopes, P Santos, N Ribeiro, I Terra
N-terminal pro-BNP predicts mortality better than procalcitonin in abdominal severe sepsis and septic shock
N Ruiz-Vera, MJ Antolino-Martinez, A Gonzalez-Lisorge, C Garcia-Palenciano, T Sansano-Sanchez, F Acosta-Villegas
Prognostic value of proadrenomedullin in severe sepsis and septic shock patients with community-acquired pneumonia
B Suberviola, A Castellanos, L García Astudillo, D Iglesias, F Ortiz Melon
Influence of TIMP-1/MMP-9 ratio on the severity and mortality in sepsis
L Lorente, MM Martín, J Solé-Violán, J Blanquer, L Labarta, C Díaz, JM Borreguero-León, JA Páramo
Impact of pro-domain stability of matrix metalloproteinase-8 on the outcome of sepsis
J McLaughlin, J Rella, A Bakan, L Kong, L Zhu, D Frederick, S Yende, R Ferrell, I Bahar, S Shapiro, D Angus, A Kaynar
Pentraxin 3 levels from bronchoalveolar lavage of critically ill patients predict lung infection
T Mauri, A Pradella, A Confalonieri, G Bellani, D Ferlicca, M Bombino, I Cuccovillo, N Patroniti, A Mantovani, A Pesenti
Increased levels of soluble triggering receptor expressed on myeloid cells sTREM1 in ICU patients with cardiovascular disease and associated organ dysfunction
S Dewan, A Varma, M Talegaonkar
Bronchoalveolar lavage/blood ratio of surface TREM-1 on CD14-positive monocytes is diagnostic of ventilator-associated pneumonia
V Grover, P Kelleher, D Henderson, P Pantelidis, F Gotch, N Soni, S Singh
Angiotensin-converting enzyme (ACE) insertion/deletion polymorphism and circulating ACE levels are not associated with outcome in septic critically ill patients
I Tsangaris, A Tsantes, P Kopterides, G Tsaknis, G Antonakos, D Konstantonis, A Nikolaidou, E Vrigkou, A Tsante, A Anthi, S Orfanos, K Dima, A Armaganidis
Comparison of the effects of recombinant human soluble thrombomodulin for systemic inflammatory response syndrome-associated coagulopathy with and without continuous hemodiafiltration
SM Matsuo, T Ikeda, K Ikeda, H Ikeda, S Suda, M Hiramatsu
Microcirculatory effect of hyperbaric oxygen therapy in septic patients
F Ferré, S Silva, J Ruiz, A Mari, O Mathe, P Sanchez-Verlaan, B Riu-Poulenc, O Fourcade, M Génestal
Lipid metabolism in critically ill patients: a microdialysis study
M Theodorakopoulou, N Nikitas, S Orfanos, I Maratou, E Boutati, A Diamantakis, A Armaganidis, I Dimopoulou
Does each element of the sepsis resuscitation bundle equally improve patient outcome?
B Afessa, MT Keegan, GE Schramm, O Gajic
Multicenter trial of a perioperative protocol to reduce mortality in critically ill patients with peptic ulcer perforation: the PULP trial
M Hylander Møller
Effect of organ failure on outcomes in neutropenic sepsis
D Bareisiene, R Kapoor
Belgian dispatchers' telephone cardiopulmonary resuscitation protocol training: an evaluation study
A Ghuysen, M El FAssi, S Stipulante, V D'orio
Comparison of the Mapleson C circuit, 500 ml and 1.6 l self-inflating bags for delivering guideline-compliant ventilation during simulated adult cardiopulmonary resuscitation
P Sherren, A Lewinsohn, T Jovaisa, S Wijayatilake
Comparison of nifekalant and amiodarone for resuscitation after cardiopulmonary arrest due to shock-resistant ventricular fibrillation
N Harayama, S Nihei, Y Isa, H Arai, T Shinjou, K Nagata, M Ueki, K Aibara, M Kamochi
Implementation of the FAST emergency vehicle pre-emption system may improve the outcomes of out-of-hospital cardiac arrests: a 7-year observational study
H Inaba, Y Tanaka, K Fukushima, S Tamasaku
Responsiveness to EMT-performed basic CPR and its duration predict unachievable sustained return of spontaneous circulation and unavoidable hospital death in unwitnessed out-of-hospital cardiac arrests without bystander CPR
H Inaba, Y Takei, M Enami, Y Goto, K Ohta
Is intraosseous access a safe option in adult cardiac arrest? A review of the literature
J Baombe, B Foex
A survey on laypersons' willingness in performing cardiopulmonary resuscitation
T Otani, S Ohshimo, T Shokawa, K Nishioka, J Itai, T Sadamori, Y Kida, T Inagawa, Y Torikoshi, K Suzuki, K Ota, T Tamura, R Tsumura, Y Iwasaki, N Hirohashi, K Tanigawa
Effects and limitations of an automated external defibrillator with audiovisual feedback for cardiopulmonary resuscitation: a randomized manikin study
H Fischer, J Gruber, S Neuhold, S Frantal, E Hochbrugger, B Steinlechner, R Greif
Introduction of the 2005 cardiopulmonary resuscitation guidelines did not increase return of spontaneous circulation in a physician-staffed prehospital emergency medical system
G Gemes, S Wallner, G Wildner, M Rigaud, G Prause
Subarachnoid hemorrhage and cardiac arrest: should every resuscitated patient receive cranial imaging?
C Leithner, D Hasper, CJ Ploner, C Storm
Predicting survival in cardiac arrest patients admitted to intensive care using the Prognosis After Resuscitation score
R Porter, I Goodhart, A Temple
Survival after cardiac arrest: what is the situation in Lithuania?
A Macas, G Baksyte, L Pieteris, A Vilke, A Peckauskas
Incidence of lower respiratory tract infections in patients treated with post-cardiac arrest mild therapeutic hypothermia and selective digestive tract decontamination
NA Vellinga, EC Boerma, MA Kuiper
Earlier intra-arrest transnasal cooling may be beneficial
M Castren, P Nordberg, FS Taccone, JL Vincent, L Svensson, D Barbut
Hyperoxia post cardiac arrest: experience of a UK ICU
L Tameem, K Rooney, S Deep, M Thomas
Ammonia and lactate blood levels on hospital arrival predict neurological outcome in patients with out-of-hospital cardiac arrest
K Shinozaki, S Oda, T Sadahiro, M Nakamura, Y Hirayama, E Watanabe, Y Tateishi, K Nakanishi, N Kitamura, H Hirasawa
Use of the Medicool™ cooling system to increase efficacy of therapeutic hypothermia post cardiac arrest
I Goodhart, R Porter, A Temple
Choline kinetics in patients undergoing hypothermia treatment: a case observation in six cardiac arrest patients
T Schröder
Employing knowledge translation interventions to increase the use of therapeutic hypothermia post arrest: the SPARC Network Trial
LJ Morrison, P Dorian, KN Dainty, S Brooks, K Thorpe, C Zhan, D Scales
Microvascular dysfunction in patients after successful resuscitation
P Biever, T Schwab, P Roos, O Willnauer, U Denz, K Fink, C Bode, HJ Busch
Application of high-frequency jet ventilation for patients with severe traumatic brain injury
DM Sabirov, RN Akalaev, MB Krasnenkova, AL Rosstalnaya
Efficacy and safety of dopamine agonists in traumatic brain injury: a systematic review of randomized controlled trials
AJ Frenette, S Kanji, L Rees, DR Williamson, MM Perreault, AF Turgeon, F Bernard, DA Fergusson
Update on the RESCUEicp decompressive craniectomy trial
PJ Hutchinson, AG Kolias, I Timofeev, E Corteen, M Czosnyka, DK Menon, JD Pickard, PJ Kirkpatrick
Optimising follow up and outcome assessments in traumatic brain injury trials
LJ Murray, JD Cooper, JV Rosenfeld, Y Arabi, A Davies, P D'Urso, T Kossmann, J Ponsford, P Reilly, I Seppelt, R Wolfe, S Vallance, B Howe, M Alkishi
Optimising the consent process in severe traumatic brain injury trials
LJ Murray, D Cooper, JV Rosenfeld, Y Arabi, A Davies, P D'urso, T Kossmann, J Ponsford, P Reilly, I Seppelt, R Wolfe
Early clinical indices predicting functional survival in severely head-injured patients
M Zouka, G Tsaousi, E Anastasiou, E Geka, E Euthymiou, I Soultati, M Giannakou
Prognostic value of prehospital single measurement of N-terminal pro-brain natriuretic peptide and troponin T after acute ischemic stroke
S Grmec, B Kit, E Hajdinjak
Stroke and thrombolysis: an old disease with a new approach
N Catorze, L Pessoa, M Abu Hazima, F Carrilho
Cerebral vasoreactivity is not impaired in patients with severe sepsis
S Szatmári, Z Fülep, P Sárkány, C Antek, P Siró, C Molnár, B Fülesdi
Significance of admission temperature and impact on mortality in critically ill neurological patients
F Rincon, C Schorr, C Hunter, B Milcareck, R Dellinger, J Parrillo, S Zanotti
Prognostic value of brain glucose levels in the outcome of patients with spontaneous cerebral hemorrhage
DC Papadopoulos, TK Zafeiridis, M Mpakopoulou, G Paraforos, A Chovas, V Christodoulou, A Komnos
Potential use of transcranial sonography in the sick patient
G Hadjipavlou, O Touma
Correlation of thermal Doppler flowmetry, brain tissue oxygen and microdialysis values in patients with severe subarachnoid hemorrhage and traumatic brain injury: a preliminary report
DC Papadopoulos, A Komnos, AS Filippidis, T Chatzopoulos, KN Fountas, G Vretzakis, K Paterakis, D Karangelis, TK Zafeiridis
UK practice in management of patients with poor-grade subarachnoid haemorrhage
H Langrick, C Hammell, E O'Callaghan, G Dempsey
Increased plasma neutrophil gelatinase-associated lipocalin levels in poor-grade aneurysmal subarachnoid hemorrhage at admission to the ICU
M Terwiel, H De Geus, J Bakker, M Van der Jagt
Spontaneous subarachnoid hemorrhage: clinical impact, prognostic value and complications
M Mourelo-Fariña, A Aller-Fernández, P Vidal-Cortés, R Galeiras, M García
Global cerebral edema and brain metabolism after subarachnoid hemorrhage
R Helbok, J Claassen
Incidence, risk factors, and impact on mortality of status epilepticus in sepsis in the United States
J Urtecho, A Seifi, M Maltenfort, M Vibbert, W McBride, M Moussouttas, J Jallo, R Bell, F Rincon
Seizure attacks in viral encephalitis: influence on a course and outcome
E Rzadkiewicz, D Lipowski
Incidence, risk factors, and impact on hospital mortality of status epilepticus after subdural hemorrhage in the United States
A Seifi, J Urtecho, M Maltenfort, M Vibbert, W McBride, M Moussouttas, J Jallo, R Bell, F Rincon
Electrographic seizures after subarachnoid hemorrhage lead to derangement of brain homeostasis in humans
J Claassen, A Perotte, D Albers, J Schmidt, B Tu, N Badjatia, K Lee, S Mayer, E Connolly, L Hirsch, G Hripcsak
Continuous electroencephalography in the surgical ICU
A Wahl, P Kurtz, R Bauer, L Hirsch, J Claassen
Continuous electroencephalography in the medico-surgical intensive care setting in Brazil: initial experience after 4 months of implementation
P Kurtz, D Santos, P Horta Gomes, C Andre, R Lima, J Kezen, L Lopes, M Kalichsztein, G Nobre
Nursing environment and delirium in ICU patients
IJ Zaal, LM Peelen, CF Spruyt, J Kesecioglu, AJ Slooter
Development and validation of an eight-step flowchart based on the CAM-ICU: a quick and highly adaptable tool to determine the presence of delirium in ICU patients
IJ Zaal, LM Peelen, D Van Dijk, AJ Slooter
Delirium assessment in daily critical care with the CAM-ICU: a multicenter study
MM Van Eijk, M Van den Boogaard, AJ Slooter
Assessment of delirium in intensive care using the CAM-ICU
R Shetty, K Reid
Impact of delirium in critically ill patients on long-term health-related quality of life and cognitive functioning
M Van den Boogaard, L Schoonhoven, A Evers, J Van der Hoeven, TH Van Achterberg, P Pickkers
Effect of rivastigmine as an adjunct to usual care with haloperidol on duration of delirium and mortality in critically ill patients: a multicentre, double-blind, placebo-controlled randomised trial
MM Van Eijk, KC Roes, ML Honing, MA Kuiper, A Karakus, M Van der JAgt, PE Spronk, WA Van Gool, RC Van der Mast, J Kesecioglu, AJ Slooter
Biomarkers of delirium in critically ill patients
M Van den Boogaard, L Schoonhoven, K Quinn, M Kox
Is delirium associated with pain and administered morphine in patients in the ICU after cardiac surgery?
L Van Gulik, H Brouwer, SJ Ahlers, W Van Boven, CA Knibbe, E Van Dongen, P Bruins
Modified Lund concept versus cerebral perfusion pressure-targeted therapy: a randomized controlled study in patients with secondary brain ischaemia
MA Hamdan, K Dizdarevic
Brain midline shift assessment using sonography in neurocritical care patients
J Motuel, I Biette, C Cognard, O Fourcade, T Geeraerts
Hypernatremia in neurointensive care: results of a 5-year prospective study
V Spatenkova, A Kazda, P Suchomel
Paracetamol-induced skin blood flow and blood pressure changes
M Boyle, A Lau, L Nicholson, M O'Brien, G Flynn, D Collins, W Walsh, D Bihari
Intravenous paracetamol pharmacokinetics in neonates: a pooled analysis
K Allegaert, G Palmer, B Anderson
Tramadol and O-demethyltramadol disposition in humans: a pooled study
K Allegaert, U Stamer, B Anderson, S Holford, A Rochette, I Troconiz, R Pedersen, N Holford
Bispectral index monitoring reduces sedative and vasopressor requirements during percutaneous tracheostomy
P Hampshire, A Guha, I Welters, J Murphy, L Poole
How is sedation provided for percutaneous dilatational tracheostomy in English ICUs?
P Hampshire, L McCrossan
Meta-analysis of detection of respiratory events during procedural sedation
JB Waugh, YA Khodneva, CA Epps
Decreased postoperative nausea and vomiting with dexmedetomidine after off-pump coronary artery bypass grafting
H Okawa, T Ono, E Hashiba, T Tsubo, H Ishihara, K Hirota
Heart rate variability during infusion of dexmedetomidine
T Imabayashi, K Ikoma, T Kikuchi, Y Kakihana, Y Kanmura
Pharmacokinetics of long-lasting, high-dose dexmedetomidine infusions in critically ill patients
T Iirola, R Aantaa, R Laitio, E Kentala, M Lahtinen, A Wighton, C Garratt, T Ahtola-Sätilä, KT Olkkola
Hemodynamic, metabolic and inflammatory effects of dexmedetomidine in a pig model of septic shock
P Carnicelli, D Fantoni, D Otsuki, A Monteiro Filho, M Kahvegian, J Noel-Morgan, J Auler Jr
Dexmedetomidine improves attention and recall in agitated critically ill patients
MM Mirski, RG Gill, PM Murakami, CT Thompson, JL Lewin
Skin conductance variability in ICU patients: an observational study of the relation to pain and Motor Activity Assessment Scale level
AC Günther, AR Schandl, H Storm, P Rossi, PV Sackey
Change in hypnotic sedative choice over time as a surrogate marker of improved performance
T Hughes, F Hanks, P Hopkins
What happens to all that propofol during prolonged sedation?
N Cowley, TH Clutton-Brock
Psychological long-term effects of a no-sedation protocol in critically ill patients
T Strøm, M Stylsvig, P Toft
Cannabinoid receptor-1 inhibition causes anesthetic-induced excitation in septic rats
R Kuschnereit, C Lehmann, S Whynot, O Hung, R Shukla, D Henzler, V Cerny, D Pavlovic, M Kelly
Introduction of a remifentanil-based analgo-sedation protocol leads to a reduction of duration of mechanical ventilation and ICU stay in critically ill patients
J Van den Bosch, J Van Bommel, J Bakker, D Gommers
Validity and reliability of the Johns Hopkins Adapted Cognitive Exam for critically ill patients
MM Mirski, JL Lewin, SL Ledroux, KS Shermock, CT Thompson, HG Goodwin, EM Mirski, RG Gill
UDP glucuronosyltransferase 2B7 single nucleotide polymorphism (rs7439366) influences heat pain response in human volunteers after i.v. morphine infusion
KM Meissner, HM Meyer zu Schwabedissen, CG Göpfert, MD Ding, JB Blood, KF Frey, HK Kim, EK Kharasch
Metformin increases skeletal muscle lactate production in pigs: a microdialysis study
A Protti, P Properzi, S Magnoni, A Santini, T Langer, S Guenzani, P Bertoli, N Stocchetti, L Gattinoni
Bilirubin and carboxy-hemoglobin concentrations in critically ill patients: prognostic significance of free heme metabolites
H Morimatsu, F Takatsu, J Matsumi, M Tani, Y Moriya, J Kosaka, K Morita
Effects of N-acetylcysteine on the erythrocyte and liver cholinesterase, nitric oxide and malondialdehyde levels in acute organophosphate toxicity
A Bayır, H Kara, Ö Köylü, R Kocabaş, A Ak
Effects of CoQ10 on the erythrocyte and heart tissue cholinesterase, nitric oxide and malondialdehyde levels in acute organophosphate toxicity
A Bayır, H Kara, Ö Köylü, R Kocabaş, A Ak
Natriuretic peptide-induced hyponatremia in a patient with left atrial myxoma
D Ramnarain, N Mehra
Hypophosphatemia of prognostic value in acute exacerbation of COPD
N Makhoul, R Farah, L Jacobson
Investigation and management of hypocalcaemia amongst critically ill patients
A Carins, M Mogk, ID Welters
Seasonal vitamin D variability and its effects on the innate immune response during human endotoxemia
MJ Van den Berg, M Kox, AJ Van der Ven, JP Wielders, P Pickkers
High bone turnover in critically vitamin-D-deficient patients
K Amrein, H Sourij, A Holl, C Schnedl, TR Pieber, H Dobnig
Low whole blood selenium level is associated with higher mortality and longer ICU and hospital stay in patients undergoing elective cardiac surgery
G Koszta, Z Kacska, K Szatmári, T Szerafin, C Mitre, B Fülesdi
Effects of high doses of selenium on the antioxidant status after liver resection
O Obukhova, S Kashiya, E Gorojanskaya, J Chekini, S Sviridova
Nutritional support in severe traumatic brain injury
MN Cote, F Lauzier, V Bibeau, P Labbe, AF Turgeon
Energy deficit and hospital length of stay can be reduced by quality management of nutrition therapy: the ICU dietitian is essential
L Soguel, JP Revelly, C Longchamp, MD Schaller, MM Berger
Enteral feed absorption during therapeutic hypothermia following out-of-hospital cardiac arrest
C Smith, J Nolan, M Williams
Enteral nutrition in mechanically ventilated patients with cervical spinal cord injury
S OConnor, Y Yau, R Yandell, K Lange, J Alexander, B Freeman, M Chapman
Nasogastric feeding intolerance in the critically ill
S OConnor, J Rivett, A Poole, A Deane, K Lange, R Yandell, Q Nguyen, R Fraser, M Chapman
Enteral nutrition products in ICUs: data from NutritionDay
B Mora, M Mouhieddine, P Singer, S Ruiz-Santana, M Hiesmayr
Protein losses and nitrogen balance during continuous renal replacement therapy
H Hayami, O Yamaguchi, M Shimosaka, H Fujimoto, S Tsuboi, M Satou
Impact of cumulative calorie and protein deficits in critically ill patients
R Dey, M Bhattacharyya, S Todi
Lipid-enriched and protein-enriched enteral nutrition limits inflammation in a human endotoxemia model
M Kox, T Lubbers, JJ De Haan, JW Greve, JC Pompe, BP Ramakers, P Pickkers, WA Buurman
Inflammation causes arginine to become an essential amino acid in critically ill children
CT De Betue, DA Van Waardenburg, KF Joosten, NE Deutz
Comparison of the effects of intravenous, enteral and enteral + intravenous supply of glutamine on malnutrition in sepsis
G Koksal, G Karaören, H Akarcay, E Karabulut, Y Tunali, S Vehid, H Oz
Insufficient activation of autophagy allows accumulation of cellular damage and may contribute to sustained organ failure in prolonged critically ill patients
J Gunst, S Derde, I Derese, M Boussemaere, F Güiza, W Martinet, JP Timmermans, A D'Hoore, PJ Wouters, G Van den Berghe, I Vanhorebeek
Glucose absorption following gastric and small intestinal nutrient administration in the critically ill
M Chapman, A Deane, A Di Bartolemeo, A Zaknic, M Summers, N Nguyen, L Besanko, C Burgstad, M Horowitz
Enhanced insulin sensitivity variability in the first 3 days of ICU stay: implications for tight glycemic control
JG Chase, AJ Le Compte, S Penning, KT Moorhead, P Massion, JC Preiser, CG Pretty, GM Shaw, T Desaive
Endogenous insulin secretion and suppression during and after sepsis in critically ill patients: implications for tight glycemic control protocols
CG Pretty, PD Docherty, J Lin, L Pfeifer, U Jamaludin, GM Shaw, AJ Le Compte, JG Chase
Effects of hyperglycemia and intensive insulin therapy on neurons and glial cells during critical illness
R Sonneville, H Den Hertog, F Güiza, I Derese, JP Brouland, F Gray, F Chrétien, T Sharshar, D Annane, G Van den Berghe, I Vanhorebeek
Errors in preparation of insulin infusions for critically ill patients
R Pierson, I Mackenzie
Blood glucose variability, measured as mean absolute glucose, strongly depends on the frequency of blood glucose level measurements
RE Harmsen, F Van Braam Houckgeest, PE Spronk, MJ Schultz, A Abu-Hanna
Validation of a virtual patient and virtual trials method for accurate prediction of tight glycemic control protocol performance
F Suhaimi, AJ Le Compte, S Penning, CG Pretty, JC Preiser, GM Shaw, T Desaive, JG Chase
Intensive insulin therapy-associated costs differ substantially between ICUs
RE Harmsen, F Van Braam Houckgeest, JP Van der Sluijs, PE Spronk, MJ Schultz
Tight glucose control managed by ICU nurses induces extremely low rates of hypoglycemia
F Delodder, C Joseph, P Maravic, T Szostek, MD Schaller, M Berger, JP Revelly, P Eggimann
Investigation of the blood glucose target for mortality reduction by means of bedside-type artificial pancreas
M Hoshino, Y Haraguchi, I Mizushima, M Sakai, K Oda, S Kajiwara, M Takagi
Mild hypoglycemia is independently associated with increased mortality in the critically ill
J Krinsley, MS Schultz, P Spronk, R Harmsen, F Van Braam Houckgeest, J Van der Sluijs, C Melot, JC Preiser
Malglycemia is strongly associated with increased risk of ICU-acquired infection
J Krinsley, MJ Schultz, TS Hall, S Krasnica, JC Preiser
Intensive insulin therapy-induced severe hypoglycemia does not affect long-term functional and cognitive outcome or health-related quality of life
RE Harmsen, JG Hofhuis, J Korevaar, F Van Braam Houckgeest, JP Van der Sluijs, MJ Schultz, PE Spronk
Decreased intravenous glucose intake safely prevents hyperglycemia in postsurgical children
CT De Betue, SC Verbruggen, H Schierbeek, S Chacko, JB Van Goudoever, KF Joosten
Space GlucoseControl with the incorporated enhanced model predictive control algorithm is a safe and reliable tool for glycaemic control in medical ICU patients
K Amrein, M Ellmerer, R Hovorka, KH Smolle, N Kachel, TR Pieber, J Plank
Glycemic control in critically ill infants and children: achieved quality of control in daily clinical practice in Leuven after a RCT
E Voets, T Van Herpe, L Desmet, D Vlasselaers, P Wouters, G Van den Berghe
Glycemia in blood, brain and subcutaneous tissue measured by a continuous glucose monitoring system
M Zourek, Z Jankovec, P Hykova
Evaluation of a continuous blood glucose monitoring system using central venous microdialysis
F Möller, J Liska, A Franco-Cereceda
Accuracy of glucose measurements in critically ill patients
V Claverie, L Lonjaret, B Riu-Poulenc, S Silva, T Geeraerts, O Fourcade
Alarm performance in a novel continuous glucose monitor
R Gottlieb, N Yang, F Luo, C Chiu, R Joshi, S Smith
Salivary cortisol measurements in mechanically ventilated patients
D Vassiliadi, I Mavrou, M Tzanela, N Nikitas, M Theodorakopoulou, S Orfanos, A Armaganidis, S Tsagarakis, I Dimopoulou
Plasma free cortisol and b-type natriuretic peptide in septic shock
D Sturgess, B Venkatesh
Interstitial cortisol levels obtained by adipose tissue microdialysis in mechanically ventilated septic patients: correlations with total and free serum cortisol
M Theodorakopoulou, N Nikitas, I Ilias, M Tzanela, D Vassiliadi, P Kopterides, N Maniatis, A Diamantakis, S Orfanos, I Perogamvros, A Armaganidis, U Ungerstedt, K Keevil, T Tsagarakis, D Dimopoulou
Early administration of hydrocortisone replacement after advent of septic shock is a major determinant of final outcome
C Katsenos, I Tsagkaris, A Antonopoulou, A Savva, A Michaloglou, E Giamarellos-Bourboulis, A Armaganidis, K Mandragos
Low preoperative total lymphocyte count as a predictor of poor outcome in adult cardiac surgery
V Lomivorotov, S Efremov, V Boboshko
Usefulness of presepsin (sCD14-ST) measurements as a marker for the diagnosis and severity of sepsis in systemic inflammatory response syndrome
T Shozushima, Y Suzuki, T Masuda, G Takahashi, S Endo
Assessment of IL-18 values in septic acute lung injury/acute respiratory distress syndrome patients
T Masuda, Y Suzuki, T Shozushima, S Endo
Activation of endothelial damage by TNFα and IFNγ in ischemia/reperfusion injury and systemic inflammation
A Golovkin, E Grigoryev, V Matveeva, G Plotnikov, D Shukevich
SAPO-1/Fas and sFas-L ratio, level of Bcl-2 and p53 as a predictors of multiple organ dysfunction syndrome in polytrauma
A Kiseleva, E Grigoryev, Y Churlyaev, A Radivilko
Sulfonated immunoglobulin improves cardiopulmonary functions by promoting IGF-I production in ARDS patients with severe sepsis
Y Deguchi, H Suga, T Sato, N Harada, T Nakagawa, K Okajima
Fluorinated groups mediate the immunomodulatory effects of volatile anesthetics in acute pulmonary inflammation
M Urner, I Herrmann, B Müller-Edenborn, L Limbach, W Stark, B Beck-Schimmer
Soluble triggering receptor expressed on myeloid cells as a marker of non-infectious systemic inflammatory response syndrome
E Grigoryev, A Golovkin, V Matveeva, G Plotnikov, D Shukevich
Anemia profile in critical septic patients hospitalized in the ICU
M De la Torre-Prados, A García-de la Torre, J Rodriguez-Vidal, M Nieto-Gonzalez, C Ortiz-García, A García-Alcántara
The normobaric oxygen paradox: does it increase haemoglobin?
S Theunissen, D De Bels, J Devriendt, P Germonpré, P Lafere, J Valsamis, T Snoeck, P Meeus, C Balestra
Transfusion of red blood cells does not increase transcutaneous oxygen tension
O Schlager, M Gschwandtner, M Nikfardjam, R Koppensteiner, G Heinz
Role of CD40 ligand in transfusion-related acute lung injury
PR Tuinman, M Gerards, G Jongsma, L Boon, AP Vlaar, NP Juffermans
Tissue oxygen monitoring leads to lower rates of blood transfusions
A Loukas, C Matadial, J Yapor, R Martinez-Ruiz
Central venous to arterial carbon dioxide gap as an indicator of oxygen debt in isovolemic anemia
S Kocsi, G Demeter, D Erces, J Kaszaki, Z Molnar
Blood transfusion during cardiac surgery dose-dependently stimulates inflammation and coagulopathy in the lung: a case-control study
PR Tuinman, AP Vlaar, AD Cornet, JJ Hofstra, M Levi, JC Meijers, A Beishuizen, MJ Schultz, JB Groeneveld, NP Juffermans
Red blood cell transfusion thresholds in pediatric septic patients
O Karam, M Tucci, T Ducruet, H Hume, J Lacroix, F Gauvin
Accuracy of a continuous non-invasive hemoglobin monitor in the ICU
D Frasca, C Dahyot-Fizelier, C Karen, Q Levrat, N Soumagne-Vialle, M Boisson, B Debaene, O Mimoz
Safety and effectiveness of different treatment regimes with tranexamic acid in elective cardiopulmonary bypass patients
JL Iribarren, JJ Jimenez, M Brouard, C Llanos, J Cabrera, L Lorenzo, R Perez, S Palmero, N Perez, L Lorente, M Mora, R Martinez
Anticoagulant effect of prothrombin complex concentrates: a whole blood in vitro study
G Scharbert, U Thaler, C Weilnböck, L Wetzel, S Kozek-Langenecker
Failure to correct the international normalized ratio in patients with anticoagulant-related major bleeding is associated with increased 90-day mortality
J Menzin, L White, M Friedman, C Nichols, JA Menzin, C Jones, J Hoesche
Thromboembolic risks of recombinant factor VIIa use in warfarin-associated intracranial hemorrhage
S Chou, X Cai, R Konigsberg, L Bresette, G Henderson, F Sorond, A Ropper, S Feske
Does the coagulation profile really matter in central venous cannulation? A review of the literature
J Baombe, L Sultan, B Foex
Monitoring of coagulation in patients after abdominal cancer surgery
O Tarabrin, V Suslov, S Kalinchuk, S Shcherbakov, D Gavrychenko
Overuse of coagulation parameter testing in critically ill patients
V Bibeau, F Lauzier, MN Cote, AF Turgeon
Applying a new method for studying the functional state of hemostasis in clinical practice
O Tarabrin, I Tyutrin, S Kalinchuk, A Turenko, S Shcherbakov, D Gavrychenko
Comparison of point-of-care thrombelastography versus conventional coagulation tests in the emergency department management of trauma
V Jeger, S Willi, T Liu, L Omert, A Orr, MA Popovsky, H Zimmermann, AK Exadaktylos
Effect of hypothermia on coagulation functions in Sprague-Dawley rats with uncontrolled hemorrhagic shock
KH Park
Sepsis: thrombocytopenia is bad, not recovering thrombocytopenia is too bad
W Faviere, T Boechat
Thrombocytopenia: incidence and clinical impact on ICU mortality
M Kompoti, M Michalia, P Peppa, F Nanou, M Charitidi, M Sartzi, I Vassiliadis, G Kallitsi, P Clouva-Molyvdas
Sepsis-induced thrombocytopenia: early prediction and modifiable mortality
G Georgiev, S Milanov, V Todorova, L Kozarov, M Milanov
Biochemical and hematological parameters (including thromboelastography) differ in patients with sepsis and SIRS after esophagectomy
M Durila, J Bronský, T Haruštiak, A Pazdro, M Pechová, K Cvachovec
Use of thromboelastography in severe sepsis: a case-control study
A Cortegiani, L Marino, F Montalto, M Milana, A Di Benedetto, L Vento, SM Raineri
Effect of anemia on coagulation and platelet function: a whole blood in vitro study
G Scharbert, L Wetzel, L Berlinger, S Kozek-Langenecker
Effect of pH levels on platelet aggregation and coagulation: a whole blood in vitro study
G Scharbert, G Franta, L Wetzel, S Kozek-Langenecker
Hemostasis system condition in progress of sepsis in severe burns
M Presnyakova, S Evstigneev
Muscular compartment syndrome and in vivo optical spectroscopy monitoring: a new model
F Ponchon, P Forget, M Vanhoonacker, G Stoquart, T Lejeune, F Lois, D Kahn, M De Kock
Effects of sepsis on venous microcirculation: non-invasive evaluation by quantitative near-infrared spectroscopy
V Papi, V Defraia, M Sandri, R Romano, R De Blasi
Role of microcirculatory monitoring in polytraumatic patients
A Donati, S Loggi, R Domizi, MR Lombrano, V Fiori, A Valentini, MC Melia, C Scorcella, A Carsetti, P Pelaia
Early trauma deaths in a level 1 trauma center: whole-body 16-MDCT is associated with a threefold increase in the time interval from hospital access to emergency surgery if compared with a US-based protocol
G Nardi, E Cingolani, S Rogante, C Siddi, G Ranaldi, AP Cossu, D Piredda
Diagnostic value of duplex ultrasonography in comparison with conventional angiography in the assessment of traumatic arterial injuries of the extremities
H Ravari
Simple predictive scoring system for ventilator-associated pneumonia in trauma patients
N Saito, T Yagi, Y Hara, H Matsumoto, K Mashiko
Effect of a trauma proforma on the quality of documentation in the Emergency Department
JE Millar, B Fisher, R McLaughlin
Efficiency of a French-language triage algorithm in the Emergency Department
J Jobé, A Ghuysen, P Gérard, V D'Orio
Optimized patient transfer using an innovative multidisciplinary assessment in the Kanton Aargau (OPTIMA I): an observational survey in lower respiratory tract infections
F Dusemund, W Albrich, K Rüegger, R Bossart, K Regez, U Schild, A Conca, P Schuetz, T Sigrist, A Huber, B Reutlinger, B Müller
Agreement of pain assessment between nurses and patients in the Emergency Department
M Modanloo, H Abdollahi, N Behnampour
Effect of delayed ICU admission on mortality and morbidity
R Ramaiah, B Shepard, P Hopkins, R Maharaj
Case note and chart review of mortality in patients with a predicted low risk of death on admission to the ICU
S Elia, R Fisher, M Mostert
Cost impact of blocking: predictability of ICU patient throughput and cost variance using process modeling
S Nabors, T Bountourelis, A Schaefer, L Luangkesorn, J Kharoufeh, L Maillart, W Yang, G Clermont
ICU readmission: good or bad?
E Potter, D Vondra, S Green, M Zuleika
Is the ASA physical status classification system a good prognostic index for ICU admissions?
A Gregório, A Pais-de-Lacerda, C França
Factors and consequences associated with a delay in the discharge process of patients from an adult critical care unit
J Mellinghoff, A Rhodes, M Grounds
Length of hospital stay prior to ICU admission and outcome
K Simpson, G Williams, T Quasim
Intensive care admission triage for a pandemic: are government tools acceptable to UK intensivists?
DT Ashton-Cleary, NV Freeman, A Tillyard
Patients' profile admitted to the ICU after establishment of a regulatory policy system for ICU patient allocation at public hospitals in Rio de Janeiro, Brazil
R Goldwasser, S Oliveira, C David, M Oliveira, A Babo
Changes in very older person admissions to an ICU over a decade
J Connelly, E Dawe, H Jones
Effect of introducing training in assessment tools for foundation trainees (F2) in intensive care and anaesthesia in a UK teaching hospital
A Raithatha, A Khaliq, P Prashast, D Bryden
Model Team in the ICU: does the implementation of intensive care assistants affect ICU nursing activity?
KB Tang
Impact of implementing a critical care team in an open general ICU
S Kim, IH Kim, S Han, SS Ki, GR Chon
Impact of a program of training on the performance of a track and trigger system and outcome of ICU admissions
M Waraich, J Zwaal, M Johnson
Impact of increased numbers of intensive care consultants on outcome in a central London teaching hospital
V Metaxa, C Bell, A Feehan, K Peters, T Chang, P Hopkins, M Ervine
Intensivist-led on-call service: key step in mortality reduction
NJ Harris, H Kilner, A Krishnamurthy, P Bishop
Mews Anesthesia Team: a project for in-hospital patient safety
R Oggioni, L Tadini Buoninsegni, G Iannello, C Rosati
Does implementing a rapid response system decrease the number of in-hospital cardiac arrests?
R So, L Te Velde, H Ponssen, M Frank, S Hendriks, E Oskam
Impact of training in the use of an early warning system on in-hospital cardiac arrests
A Raj, J Zwaal
Daily physiological goal-setting: medical prescription and nursing adherence in a London teaching hospital ICU
MK Khan, S Alawad, M Thavasothy
Automated reporting of safety bundles: streamlining the performance improvement process
W McGee, T Higgins, J Echols, H Nelson, M Tidswell
Prevalence, clinical management and risks associated with acute faecal incontinence in the critical care setting: the FIRST questionnaire survey
R Binks
Patient safety in ICUs: adverse events characterization and potential risk factors
L Zambon, R Daud-Gallotti, K Padilha, T Vasconcelos, N Inoue, F Rodrigues, L Tanigushi, I Velasco
Failure to define level 1 care
B Fletcher, C Dames, S Hutchinson, S Fletcher
Robotic telepresence in acute care facilities in community hospitals in Mexico
G Vazquez de Anda, S Larraza Rico, L De la Cruz Avila, S Resendiz, M Escudero, R Tapia Rodriguez, Y Gutierrez Mariano, G Diaz Diego, J Mejia Nava, R Camacho Beiza
System-level concentration of services for mechanically ventilated patients can mask substantial regional heterogeneity and disorganization
DJ Wallace, DC Angus, MR Rosengart, TJ Iwashyna, JM Kahn
Understanding staff perspectives on collaborative quality improvement in the ICU: a qualitative exploration
KN Dainty, DC Scales, B Hales, T Sinuff, M Zwarenstein
Improving medication safety on critical care using an anonymous electronic medication incident reporting system
H Dillon, M Rosbergen, R Wyatt, J Nortje
Reduction in the incidence of VAP and mortality rates in the ICU after implementation of hand hygiene education protocols and extensive ICU reconstruction work
K Filos, F Fligou, A Gotsi, D Velissaris, C Sklavou, M Marangos
Paediatric admissions to an adult ICU in a district general hospital in the UK
A Hazara, V Singh, P Davoudian
Factors associated with compassion fatigue among ICU nurses in Greece
P Mangoulia, G Fildissis, E Koukia, G Alevizopoulos, T Katostaras
Burnout in ICUs in Portugal: is there? Are there differences between doctors and nurses?
C Teixeira, S Pereira, O Ribeiro, A Fonseca, A Carvalho
Medical handovers in the ICU: a snapshot of practice in the South West of France
G Brenier, T Geeraerts, O Fourcade
Ratio of observed to predicted deaths in pediatric patients after introducing a closing policy in a general ICU
Y Ueno, H Imanaka, J Oto, M Nishimura
Safety programme reduces ICU mortality
KD Rooney, R Sundaram, L Gibson, RJ Price
Critical care outcome of pulmonary artery hypertension
A Philips, J Hurdman, B Batuwitage, D Kiely, G Mills
Outcomes of haematopoietic stem cell transplant patients admitted to the ICU
G Bird, K Mohammed, P Farquhar-Smith, P Gruber
Patterns of infection and impact on outcome in haematology patients admitted to intensive care
R José, I McDonald, P Pfeffer, S Shaw, C Kibbler, B Agarwal
Outcome of haematology patients admitted to intensive care in a tertiary centre: primary haematological diagnosis, recent chemotherapy and bone marrow transplantation are not associated with outcome
R José, I McDonald, P Pfeffer, S Shaw, B Agarwal
New prognosis inflammatory and nutritional indexes: comparison with the Prognostic Inflammatory and Nutritional Index as reference index
F Ziegler, L Codevelle, E Houivet, J Benichou, A Lavoinne, P Dechelotte
Feasibility and utility of frailty assessment in the over 80s on critical care
B Charles, R Porter, D Bryden
Quality of life in the over-80-year-old medical patient following intensive care
KJ Rowe, M Trivedi, A Ercole, K Gunning
Is age a predictor of mortality in medical high-dependency units?
E Hood, A Bhangu, D Pandit, A Michael
Inadvisably presenting APACHE scores as parametric data: a study of 200 original articles from leading journals
R Kam, C Bunce, JM Handy
ICU scoring systems: which one to use in oncology patients?
D Juneja, P Nasa, O Singh, R Dang, Y Javeri, G Singh
Do scoring systems predict mortality following emergency abdominal aortic aneurysm repair? The Norwich experience
S Kumar, J Nortje
Influence of resuscitation status on the performance of APACHE III, APACHE IV and SAPS III
MT Keegan, O Gajic, B Afessa
Limitations of the use of the Glasgow Coma Scale in intensive care patients with non-neurological primary disease: a search for alternatives
PV Dong, OL Cremer
ManChEWS: Royal Manchester Children's Hospital early warning score
V Joshi, R Barber, R Yates
Does an open level 2 medical high-dependency unit improve outcomes for critically ill patients? Using the APACHE II scoring system in a district general hospital in the UK
V Hurley, D Pandit
Gastrointestinal failure score alone and in combination with SOFA score in the assessment of the critically ill patients
N Abed, L Mohammed, A Metwaly, M Hussien
How high must lactate be to predict an adverse outcome?
A Reintam Blaser, J Starkopf
Outcome prediction in haematological patients requiring admission to the ICU
S Gopal, N Green, M Myint, A Jacobs
HIV-infected patients in the ICU in the current era of high-activity antiretroviral treatment
P Vidal Cortés, V Aller Fernández, M Mourelo Fariña, P Lameiro Flores, P Vázquez Rodríguez, A Castro Iglesias
Clinical characteristics and outcomes of obstetric patients requiring ICU admission
H El-Abd, K Mashhour, A Mwafy
Management and risk factors for maternal morbidity of eclampsia in a Moroccan teaching hospital
Y Zarrouki, M Boutbaoucht, Y El Waggagui, G El Adib, S Younous
Clinical and diagnostic value of transcranial cerebral oximetry in the optimization of mechanical ventilation in newborn infants
V Estrin, A Simonova
Assessment of artificial ventilation in Salvadorian public hospitals
JF Granados, PE Sobenes, MT Bertoli
Comparison of the stated religious beliefs amongst UK intensive care physicians and the UK population
A Tillyard, DT Ashton-Cleary
Characteristics of Outreach patients that received end-of-life counseling
K Kyeremanteng, RP Patel, EF Fitzgibbon
Discussing end-of-life issues with terminally ill cancer patients and their families: our results
BE Eftimova, B Lazarova
Factors associated with withdrawal of life-sustaining therapy in severe traumatic brain injury patients
N Côte, A Turgeon, F Lauzier, L Moore, JF Simard, D Scales, K Burns, M Meade, F Bernard, D Zygun, D Fergusson
Documenting end-of-life care plans on the ICU: using a digital proforma may improve compliance with nationally agreed standards
S Cantellow, D Harris, S Smith, C Bordeaux, M Thomas
Gender influences end-of-life decisions
ME Lissauer, L Smitz-Naranjo, SB Johnson
Survey of the use of ancillary tests in the diagnosis of brain stem death
A Sherrington, L Barrass, G Mandersloot, M Healy
Interactions of endotoxin, albumin function, albumin binding capacity and oxidative stress in brain-dead organ donors
V Stadlbauer, B Leber, P Stiegler, S Stanzer, U Mayrhauser, S Köstenbauer, M Sereinigg, A Puntschart, T Stojakovic, K Tscheliessnigg, K Oettl
Is there a difference in response rate and degree of satisfaction among family members of survivors and nonsurvivors at admission to intensive care?
C Teixeira, J Keating, I Silva, A Veloso, O Ribeiro, I Aragão
Patient's families in the ICU: describing their strategies to face the situation
KK Borges, MG Mello, CM David
Inter-observer agreement of Medical Research Council-sum score and handgrip strength in the ICU
G Hermans, B Clerckx, T Vanhullebusch, J Segers, G Vanpee, C Robbeets, M Casaer, P Wouters, R Gosselink, G Vandenberghe
Assessment of functional capacity after discharge from the ICU
E Caser, P Simões, A Casati, C Barbas
Rehabilitation after critical care: using audit to guide changes in practice, a multidisciplinary (MDT) approach
N Glasby, E Blake, D Green
An audit of adult critical care rehabilitation processes in a UK district general hospital based on NICE guidelines
R Agarwala, N Ahmed, K Patil
Follow-up after critical care
M Slattery, P Temblett, A Houghton, D Hope
Sunlight exposure does not influence ICU survival
R Castro, S Hong, C Lee, L Weissfeld, G Clermont, D Angus, M Rosengart
Incidents related to intrahospital transport of patients in the ICU
C Van Velzen, AH Brunsveld-Reinders, MS Arbous
Systematic review of industry-led versus investigator-led randomized controlled trials
K Kommaraju, W Kwong, J Marshall, K Burns
Female authors in top-rank journals of different medical specialties
K Amrein, C Putz-Bankuti, J Mader, A Amegah-Sakotnik, T Urbanic, D Wagner, E Prandl, N Sareban, S Amrein, A Langmann
National survey of protective eye care practices in the critically ill
R Kam, S Haldar, E Papamichael, K Pearce, M Hayes, N Joshi
Sleep disturbances in the ICU
G Langevoort, J Hofhuis, J Rommes, P Spronk
Inhaled colistin for the treatment of ventilator-associated tracheobronchitis in critically ill patients
Z Athanassa, P Myrianthefs, E Boutzouka, V Papaioannou, S Tsiplakou, A Tsakris, G Baltopoulos
Erratum to: Prevalence, clinical management and risks associated with acute faecal incontinence in the critical care setting: The FIRST questionnaire survey
C Bayón García, R Binks, E De Luca, C Dierkes, A Franci, E Gallart, G Niederalt, D Wyncoll
Erratum to: Increased levels of soluble triggering receptor expressed on myeloid cells sTREM1 in ICU patients with cardiovascular disease and associated organ dysfunction
S Dewan, A Varma, N Verma, M Talegaonkar