Ausgabe 1/2015
Inhalt (245 Artikel)
Vitamin D deficiency decreases survival of bacterial meningoencephalitis in mice
Marija Djukic, Nadine Sostmann, Thomas Bertsch, Marianne Mecke, Stefan Nessler, Anja Manig, Uwe-Karsten Hanisch, Jakob Triebel, L Cornelius Bollheimer, Cornel Sieber, Roland Nau
Retinal pericytes and cytomegalovirus infectivity: implications for HCMV-induced retinopathy and congenital ocular disease
Irene Wilkerson, Joshua Laban, Johnathan M Mitchell, Nader Sheibani, Donald J Alcendor
Spermine reverses lipopolysaccharide-induced memory deficit in mice
Pâmella Karina Santana Frühauf, Rafael Porto Ineu, Lediane Tomazi, Thiago Duarte, Carlos Fernando Mello, Maribel Antonello Rubin
Activation of toll like receptor 4 attenuates GABA synthesis and postsynaptic GABA receptor activities in the spinal dorsal horn via releasing interleukin-1 beta
Xisheng Yan, Enshe Jiang, Han-Rong Weng
Neuromelanin activates proinflammatory microglia through a caspase-8-dependent mechanism
Nikenza Viceconte, Miguel A Burguillos, Antonio J Herrera, Rocío M De Pablos, Bertrand Joseph, José L Venero
Differences in the distribution, phenotype and gene expression of subretinal microglia/macrophages in C57BL/6N (Crb1rd8/rd8) versus C57BL6/J (Crb1wt/wt) mice
Bogale Aredo, Kaiyan Zhang, Xiao Chen, Cynthia Xin-Zhao Wang, Tao Li, Rafael L Ufret-Vincenty
Activation of the nuclear receptor PPARδ is neuroprotective in a transgenic mouse model of Alzheimer’s disease through inhibition of inflammation
Tarja Malm, Monica Mariani, Lauren J Donovan, Lee Neilson, Gary E Landreth
Chemokine-mediated inflammation in the degenerating retina is coordinated by Müller cells, activated microglia, and retinal pigment epithelium
Matt Rutar, Riccardo Natoli, RX Chia, Krisztina Valter, Jan M Provis
Anti-inflammatory effects of BHBA in both in vivo and in vitro Parkinson’s disease models are mediated by GPR109A-dependent mechanisms
Shou-Peng Fu, Jian-Fa Wang, Wen-Jing Xue, Hong-Mei Liu, Bing-run Liu, Ya-Long Zeng, Su-Nan Li, Bing-Xu Huang, Qing-Kang Lv, Wei Wang, Ju-Xiong Liu
The spinal anti-inflammatory mechanism of motor cortex stimulation: cause of success and refractoriness in neuropathic pain?
Guilherme D Silva, Patrícia SS Lopes, Erich T Fonoff, Rosana L Pagano
Scutellarin regulates the Notch pathway and affects the migration and morphological transformation of activated microglia in experimentally induced cerebral ischemia in rats and in activated BV-2 microglia
Yun Yuan, Parakalan Rangarajan, Enci Mary Kan, Yajun Wu, Chunyun Wu, Eng-Ang Ling
Anti-inflammatory T-cell shift in neuropathic pain
Benjamin Luchting, Banafscheh Rachinger-Adam, Jens Heyn, Ludwig Christian Hinske, Simone Kreth, Shahnaz Christina Azad
Lipopolysaccharide binding protein, interleukin-10, interleukin-6 and C-reactive protein blood levels in acute ischemic stroke patients with post-stroke infection
Hans Worthmann, Anita B Tryc, Meike Dirks, Ramona Schuppner, Korbinian Brand, Frank Klawonn, Ralf Lichtinghagen, Karin Weissenborn
CCAAT/enhancer binding protein β directly regulates the expression of the complement component 3 gene in neural cells: implications for the pro-inflammatory effects of this transcription factor
Elena Hernandez-Encinas, Diana Aguilar-Morante, Marta Cortes-Canteli, Jose A Morales-Garcia, Elena Gine, Angel Santos, Ana Perez-Castillo
Pentraxin 3 mediates neurogenesis and angiogenesis after cerebral ischaemia
Beatriz Rodriguez-Grande, Lidiya Varghese, Francisco Molina-Holgado, Olivera Rajkovic, Cecilia Garlanda, Adam Denes, Emmanuel Pinteaux
Protective role of fingolimod (FTY720) in rats subjected to subarachnoid hemorrhage
Hao-Liang Xu, Dale A Pelligrino, Chanannait Paisansathan, Fernando D Testai
In vivo multi-modal imaging of experimental autoimmune uveoretinitis in transgenic reporter mice reveals the dynamic nature of inflammatory changes during disease progression
Xiangting Chen, Jelena M Kezic, John V Forrester, Gabrielle L Goldberg, Ian P Wicks, Claude C Bernard, Paul G McMenamin
NLRP1 inflammasome is activated in patients with medial temporal lobe epilepsy and contributes to neuronal pyroptosis in amygdala kindling-induced rat model
Chen-Chen Tan, Jian-Guo Zhang, Meng-Shan Tan, Hua Chen, Da-Wei Meng, Teng Jiang, Xiang-Fei Meng, Ying Li, Zhen Sun, Meng-Meng Li, Jin-Tai Yu, Lan Tan
The cerebrospinal fluid immunoglobulin transcriptome and proteome in neuromyelitis optica reveals central nervous system-specific B cell populations
Markus C Kowarik, Monika Dzieciatkowska, Scott Wemlinger, Alanna M Ritchie, Bernhard Hemmer, Gregory P Owens, Jeffrey L Bennett
Deferoxamine attenuates lipopolysaccharide-induced neuroinflammation and memory impairment in mice
Xiao-Ying Zhang, Jiang-Bei Cao, Li-Ming Zhang, Yun-Feng Li, Wei-Dong Mi
Danger- and pathogen-associated molecular patterns recognition by pattern-recognition receptors and ion channels of the transient receptor potential family triggers the inflammasome activation in immune cells and sensory neurons
Giorgio Santoni, Claudio Cardinali, Maria Beatrice Morelli, Matteo Santoni, Massimo Nabissi, Consuelo Amantini
Beneficial effect of chronic Staphylococcus aureus infection in a model of multiple sclerosis is mediated through the secretion of extracellular adherence protein
Prateek Kumar, Benedikt Kretzschmar, Sabine Herold, Roland Nau, Mario Kreutzfeldt, Sandra Schütze, Mathias Bähr, Katharina Hein
Anti-inflammatory activity of Wnt signaling in enteric nervous system: in vitro preliminary evidences in rat primary cultures
Rosa Di Liddo, Thomas Bertalot, Anne Schuster, Sandra Schrenk, Alessia Tasso, Ilenia Zanusso, Maria Teresa Conconi, Karl Herbert Schäfer
Treatment with AMD3100 attenuates the microglial response and improves outcome after experimental stroke
Helene L Walter, Gerlinde van der Maten, Ana Rita Antunes, Tadeusz Wieloch, Karsten Ruscher
MiR-27a ameliorates inflammatory damage to the blood-spinal cord barrier after spinal cord ischemia: reperfusion injury in rats by downregulating TICAM-2 of the TLR4 signaling pathway
Xiao-Qian Li, Huang-Wei Lv, Zhi-Lin Wang, Wen-Fei Tan, Bo Fang, Hong Ma
Attenuation of acute stroke injury in rat brain by minocycline promotes blood–brain barrier remodeling and alternative microglia/macrophage activation during recovery
Yirong Yang, Victor M Salayandia, Jeffrey F Thompson, Lisa Y Yang, Eduardo Y Estrada, Yi Yang
Liver X receptor-dependent inhibition of microglial nitric oxide synthase 2
Julie R Secor McVoy, Hanadi Ajam Oughli, Unsong Oh
Active immunization with myelin-derived altered peptide ligand reduces mechanical pain hypersensitivity following peripheral nerve injury
Chamini J Perera, Samuel S Duffy, Justin G Lees, Cristina F Kim, Barbara Cameron, Vasso Apostolopoulos, Gila Moalem-Taylor
Involvement of sigma-1 receptor in astrocyte activation induced by methamphetamine via up-regulation of its own expression
Yuan Zhang, Xuan Lv, Ying Bai, Xinjian Zhu, Xiaodong Wu, Jie Chao, Ming Duan, Shilpa Buch, Ling Chen, Honghong Yao
miR-146a suppresses cellular immune response during Japanese encephalitis virus JaOArS982 strain infection in human microglial cells
Nikhil Sharma, Ruhi Verma, Kanhaiya Lal Kumawat, Anirban Basu, Sunit K Singh
Toll-like receptor 4 inhibition within the paraventricular nucleus attenuates blood pressure and inflammatory response in a genetic model of hypertension
Rahul B Dange, Deepmala Agarwal, Ryoichi Teruyama, Joseph Francis
Sexually dimorphic outcomes and inflammatory responses in hypoxic-ischemic encephalopathy
Mehwish A Mirza, Rodney Ritzel, Yan Xu, Louise D McCullough, Fudong Liu
Transcription factor myocyte enhancer factor 2D regulates interleukin-10 production in microglia to protect neuronal cells from inflammation-induced death
Shaosong Yang, Li Gao, Fangfang Lu, Bao Wang, Fei Gao, Gang Zhu, Zhibiao Cai, Juan Lai, Qian Yang
Docosahexaenoic acid (DHA): a modulator of microglia activity and dendritic spine morphology
Philip K-Y Chang, Armen Khatchadourian, Rebecca Anne McKinney, Dusica Maysinger
Human mesenchymal stem/stromal cells suppress spinal inflammation in mice with contribution of pituitary adenylate cyclase-activating polypeptide (PACAP)
Tomomi Tsumuraya, Hirokazu Ohtaki, Dandan Song, Atsushi Sato, Jun Watanabe, Yutaka Hiraizumi, Tomoya Nakamachi, Zhifang Xu, Kenji Dohi, Hitoshi Hashimoto, Takashi Atsumi, Seiji Shioda
RNA sequencing reveals distinct mechanisms underlying BET inhibitor JQ1-mediated modulation of the LPS-induced activation of BV-2 microglial cells
Kyoung Hwa Jung, Amitabh Das, Jin Choul Chai, Sun Hwa Kim, Nishi Morya, Kyoung Sun Park, Young Seek Lee, Young Gyu Chai
Systemic lipopolysaccharide-mediated alteration of cortical neuromodulation involves increases in monoamine oxidase-A and acetylcholinesterase activity
Zhi Ming, Caitlin A Wotton, Robert T Appleton, John C Ching, Matthew E Loewen, Grzegorz Sawicki, Lane K Bekar
Mesial temporal lobe epilepsy with psychiatric comorbidities: a place for differential neuroinflammatory interplay
Ludmyla Kandratavicius, Jose Eduardo Peixoto-Santos, Mariana Raquel Monteiro, Renata Caldo Scandiuzzi, Carlos Gilberto Carlotti Jr, Joao Alberto Assirati Jr, Jaime Eduardo Hallak, Joao Pereira Leite
MCP-induced protein 1 mediates the minocycline-induced neuroprotection against cerebral ischemia/reperfusion injury in vitro and in vivo
Zhuqing Jin, Jian Liang, Jing Wang, Pappachan E Kolattukudy
Effect of thymic stimulation of CD4+ T cell expansion on disease onset and progression in mutant SOD1 mice
Rebecca K Sheean, Richard H Weston, Nirma D Perera, Angela D’Amico, Stephen L Nutt, Bradley J Turner
Determining the role of IL-4 induced neuroinflammation in microglial activity and amyloid-β using BV2 microglial cells and APP/PS1 transgenic mice
Clare H Latta, Tiffany L Sudduth, Erica M Weekman, Holly M Brothers, Erin L Abner, Gabriel J Popa, Michael D Mendenhall, Floracita Gonzalez-Oregon, Kaitlyn Braun, Donna M Wilcock
Attenuation of microglial activation in a mouse model of Alzheimer’s disease via NFAT inhibition
Lalida Rojanathammanee, Angela M Floden, Gunjan D Manocha, Colin K Combs
The matrix metalloproteinase inhibitor RS-130830 attenuates brain injury in experimental pneumococcal meningitis
Fabian D Liechti, Fabian Bächtold, Denis Grandgirard, David Leppert, Stephen L Leib
miR-15b/16 protects primary human retinal microvascular endothelial cells against hyperglycemia-induced increases in tumor necrosis factor alpha and suppressor of cytokine signaling 3
Eun-Ah Ye, Jena J Steinle
Transiently lowering tumor necrosis factor-α synthesis ameliorates neuronal cell loss and cognitive impairments induced by minimal traumatic brain injury in mice
Renana Baratz, David Tweedie, Jia-Yi Wang, Vardit Rubovitch, Weiming Luo, Barry J Hoffer, Nigel H Greig, Chaim G Pick
Anti-MOG antibodies are present in a subgroup of patients with a neuromyelitis optica phenotype
Anne-Katrin Pröbstel, Gabrielle Rudolf, Klaus Dornmair, Nicolas Collongues, Jean-Baptiste Chanson, Nicholas SR Sanderson, Raija LP Lindberg, Ludwig Kappos, Jérôme de Seze, Tobias Derfuss
Brain endogenous angiotensin II receptor type 2 (AT2-R) protects against DOCA/salt-induced hypertension in female rats
Shu-Yan Dai, Wei Peng, Yu-Ping Zhang, Jian-Dong Li, Ying Shen, Xiao-Fei Sun
Role of high mobility group box protein 1 (HMGB1) in peripheral blood from patients with multiple sclerosis
Sunny Malhotra, Nicolas Fissolo, Mar Tintoré, Ana Cristina Wing, Joaquin Castilló, Angela Vidal-Jordana, Xavier Montalban, Manuel Comabella
Endogenous antibodies contribute to macrophage-mediated demyelination in a mouse model for CMT1B
Dennis Klein, Janos Groh, Andreas Weishaupt, Rudolf Martini
EP2-PKA signaling is suppressed by triptolide in lipopolysaccharide-induced microglia activation
Ting Zhang, Xiaoli Gong, Guanzheng Hu, Xiaomin Wang
Malibatol A regulates microglia M1/M2 polarization in experimental stroke in a PPARγ-dependent manner
Jie Pan, Jia-li Jin, Hui-ming Ge, Kai-lin Yin, Xiang Chen, Li-juan Han, Yan Chen, Lai Qian, Xiao-xi Li, Yun Xu
Cannabidiol, a non-psychoactive cannabinoid, leads to EGR2-dependent anergy in activated encephalitogenic T cells
Ewa Kozela, Ana Juknat, Nathali Kaushansky, Avraham Ben-Nun, Giovanni Coppola, Zvi Vogel
Nuclear factor-κB activation in perihematomal brain tissue correlates with outcome in patients with intracerebral hemorrhage
Ze-Li Zhang, Yu-Guang Liu, Qi-Bing Huang, Hong-Wei Wang, Yan Song, Zhen-Kuan Xu, Feng Li
The induction of neuronal death by up-regulated microglial cathepsin H in LPS-induced neuroinflammation
Kai Fan, Daobo Li, Yanli Zhang, Chao Han, Junjie Liang, Changyi Hou, Hongliang Xiao, Kazuhiro Ikenaka, Jianmei Ma
Prolactin in combination with interferon-β reduces disease severity in an animal model of multiple sclerosis
Simon Zhornitsky, Trina A Johnson, Luanne M Metz, Samuel Weiss, V Wee Yong
Calcium dysregulation via L-type voltage-dependent calcium channels and ryanodine receptors underlies memory deficits and synaptic dysfunction during chronic neuroinflammation
Sarah C Hopp, Heather M D’Angelo, Sarah E Royer, Roxanne M Kaercher, Alexis M Crockett, Linda Adzovic, Gary L Wenk
Inhibition of the spinal astrocytic JNK/MCP-1 pathway activation correlates with the analgesic effects of tanshinone IIA sulfonate in neuropathic pain
Jun Tang, Chao Zhu, Zhi-hong Li, Xiao-yu Liu, Shu-kai Sun, Ting Zhang, Zhuo-jing Luo, Hui Zhang, Wei-yan Li
Role for cFMS in maintaining alternative macrophage polarization in SIV infection: implications for HIV neuropathogenesis
Lindsey Gerngross, Gabrielle Lehmicke, Aghilas Belkadi, Tracy Fischer
Involvement of phosphatase and tensin homolog deleted from chromosome 10 in rodent model of neuropathic pain
Shi-Ying Huang, Chun-Sung Sung, Wu-Fu Chen, Chun-Hong Chen, Chien-Wei Feng, San-Nan Yang, Han-Chun Hung, Nan-Fu Chen, Pey-Ru Lin, San-Cher Chen, Hui-Min David Wang, Tian-Huei Chu, Ming-Hong Tai, Zhi-Hong Wen
Inflammatory mediator release from primary rhesus microglia in response to Borrelia burgdorferi results from the activation of several receptors and pathways
Geetha Parthasarathy, Mario T Philipp
The inhibitory effect of mesenchymal stem cell on blood–brain barrier disruption following intracerebral hemorrhage in rats: contribution of TSG-6
Min Chen, Xifeng Li, Xin Zhang, Xuying He, Lingfeng Lai, Yanchao Liu, Guohui Zhu, Wei Li, Hui Li, Qinrui Fang, Zequn Wang, Chuanzhi Duan
Mature oligodendrocytes actively increase in vivo cytoskeletal plasticity following CNS damage
Giuseppe Locatelli, Arianna Baggiolini, Bettina Schreiner, Pushpalatha Palle, Ari Waisman, Burkhard Becher, Thorsten Buch
Insulin improves memory and reduces chronic neuroinflammation in the hippocampus of young but not aged brains
Linda Adzovic, Ashley E Lynn, Heather M D’Angelo, Alexis M Crockett, Roxanne M Kaercher, Sarah E Royer, Sarah C Hopp, Gary L Wenk
Neuregulin-1 inhibits neuroinflammatory responses in a rat model of organophosphate-nerve agent-induced delayed neuronal injury
Yonggang Li, Pamela J Lein, Gregory D Ford, Cuimei Liu, Kyndra C Stovall, Todd E White, Donald A Bruun, Teclemichael Tewolde, Alicia S Gates, Timothy J Distel, Monique C Surles-Zeigler, Byron D Ford
Chronic intestinal inflammation alters hippocampal neurogenesis
Svetlana Zonis, Robert N Pechnick, Vladimir A Ljubimov, Michael Mahgerefteh, Kolja Wawrowsky, Kathrin S Michelsen, Vera Chesnokova
Sterile alpha motif and histidine/aspartic acid domain-containing protein 1 (SAMHD1)-facilitated HIV restriction in astrocytes is regulated by miRNA-181a
Sudheesh Pilakka-Kanthikeel, Andrea Raymond, Venkata Subba Rao Atluri, Vidya Sagar, Shailendra K Saxena, Patricia Diaz, Semithe Chevelon, Michael Concepcion, Madhavan Nair
Bone marrow-derived macrophages from aged rats are more responsive to inflammatory stimuli
James P Barrett, Derek A Costello, Joan O’Sullivan, Thelma R Cowley, Marina A Lynch
Erratum: Should development of Alzheimer’s disease-specific intravenous immunoglobulin be considered?
David A Loeffler
Attenuation of traumatic brain injury-induced cognitive impairment in mice by targeting increased cytokine levels with a small molecule experimental therapeutic
Adam D Bachstetter, Scott J Webster, Danielle S Goulding, Jonathan E Morton, D Martin Watterson, Linda J Van Eldik
Sphingosine 1-phosphate enhances the excitability of rat sensory neurons through activation of sphingosine 1-phosphate receptors 1 and/or 3
Chao Li, Jun-nan Li, Joanne Kays, Miguel Guerrero, Grant D Nicol
Soluble amyloid triggers a myeloid differentiation factor 88 and interferon regulatory factor 7 dependent neuronal type-1 interferon response in vitro
Myles Robert Minter, Bevan Scott Main, Kate Maree Brody, Moses Zhang, Juliet Marie Taylor, Peter John Crack
Insulin-like growth factors and related proteins in plasma and cerebrospinal fluids of HIV-positive individuals
Hyeon-Sook Suh, Yungtai Lo, Namjong Choi, Scott Letendre, Sunhee C Lee
Intravenous immunoglobulin (IVIg) dampens neuronal toll-like receptor-mediated responses in ischemia
Ker Zhing Lok, Milan Basta, Silvia Manzanero, Thiruma V Arumugam
Rodent models of neuroinflammation for Alzheimer’s disease
Amir Nazem, Roman Sankowski, Michael Bacher, Yousef Al-Abed
Association of brain immune genes with social behavior of inbred mouse strains
Li Ma, Sami Piirainen, Natalia Kulesskaya, Heikki Rauvala, Li Tian
Early inflammatory mediator gene expression in two models of traumatic brain injury: ex vivo cortical slice in mice and in vivo cortical impact in piglets
David J Graber, Beth A Costine, William F Hickey
Activated microglia/macrophage whey acidic protein (AMWAP) inhibits NFκB signaling and induces a neuroprotective phenotype in microglia
Alexander Aslanidis, Marcus Karlstetter, Rebecca Scholz, Sascha Fauser, Harald Neumann, Cora Fried, Markus Pietsch, Thomas Langmann
Role of IL-16 in CD4+ T cell-mediated regulation of relapsing multiple sclerosis
Dusanka S Skundric, William W Cruikshank, Jelena Drulovic
Astrocyte response to IFN-γ limits IL-6-mediated microglia activation and progressive autoimmune encephalomyelitis
Carine Savarin, David R Hinton, Alice Valentin-Torres, Zhihong Chen, Bruce D Trapp, Cornelia C Bergmann, Stephen A Stohlman
Function and mechanism of toll-like receptors in cerebral ischemic tolerance: from preconditioning to treatment
Peng-Fei Wang, Xiao-Yi Xiong, Jing Chen, Yan-Chun Wang, Wei Duan, Qing-Wu Yang
Monoacylglycerol lipase inhibitor JZL184 reduces neuroinflammatory response in APdE9 mice and in adult mouse glial cells
Rea Pihlaja, Jatta Takkinen, Olli Eskola, Jenni Vasara, Francisco R López-Picón, Merja Haaparanta-Solin, Juha O Rinne
Systemic inflammation in early neonatal mice induces transient and lasting neurodegenerative effects
Filipa L Cardoso, Jasmin Herz, Adelaide Fernandes, João Rocha, Bruno Sepodes, Maria A Brito, Dorian B McGavern, Dora Brites
A single dose of a neuron-binding human monoclonal antibody improves brainstem NAA concentrations, a biomarker for density of spinal cord axons, in a model of progressive multiple sclerosis
Bharath Wootla, Aleksandar Denic, Jens O Watzlawik, Arthur E Warrington, Moses Rodriguez
Amyloid β peptide-induced inhibition of endothelial nitric oxide production involves oxidative stress-mediated constitutive eNOS/HSP90 interaction and disruption of agonist-mediated Akt activation
Folami Lamoke, Valeria Mazzone, Tiziana Persichini, Annamaria Maraschi, Michael Brennan Harris, Richard C Venema, Marco Colasanti, Micaela Gliozzi, Carolina Muscoli, Manuela Bartoli, Vincenzo Mollace
Brain inflammation and hypertension: the chicken or the egg?
Pawel J Winklewski, Marek Radkowski, Magdalena Wszedybyl-Winklewska, Urszula Demkow
FTY720 attenuates excitotoxicity and neuroinflammation
Raffaela Cipriani, Juan Carlos Chara, Alfredo Rodríguez-Antigüedad, Carlos Matute
Aging increases microglial proliferation, delays cell migration, and decreases cortical neurogenesis after focal cerebral ischemia
Ana Moraga, Jesús M Pradillo, Alicia García-Culebras, Sara Palma-Tortosa, Ivan Ballesteros, Macarena Hernández-Jiménez, María A Moro, Ignacio Lizasoain
CCAAT/enhancer-binding protein δ (C/EBPδ) aggravates inflammation and bacterial dissemination during pneumococcal meningitis
Mercedes Valls Serón, JanWillem Duitman, Madelijn Geldhoff, JooYeon Engelen-Lee, Stefan R Havik, Matthijs C Brouwer, Diederik van de Beek, C Arnold Spek
4′-O-methylhonokiol increases levels of 2-arachidonoyl glycerol in mouse brain via selective inhibition of its COX-2-mediated oxygenation
Andrea Chicca, Maria Salomé Gachet, Vanessa Petrucci, Wolfgang Schuehly, Roch-Philippe Charles, Jürg Gertsch
Absence of toll-like receptor 4 (TLR4) extends survival in the hSOD1G93A mouse model of amyotrophic lateral sclerosis
Jia Y Lee, John D Lee, Simon Phipps, Peter G Noakes, Trent M Woodruff
Autoantigen cross-reactive environmental antigen can trigger multiple sclerosis-like disease
Catherine J Reynolds, Malcolm J W Sim, Kathryn J Quigley, Daniel M Altmann, Rosemary J Boyton
Who let the dogs out?: detrimental role of Galectin-3 in hypoperfusion-induced retinal degeneration
Oscar Manouchehrian, Karin Arnér, Tomas Deierborg, Linnéa Taylor
Lenalidomide reduces microglial activation and behavioral deficits in a transgenic model of Parkinson’s disease
Elvira Valera, Michael Mante, Scott Anderson, Edward Rockenstein, Eliezer Masliah
Oral administration of cytosolic PLA2 inhibitor arachidonyl trifluoromethyl ketone ameliorates cauda equina compression injury in rats
Mushfiquddin Khan, Anandakumar Shunmugavel, Tajinder S Dhammu, Fumiyo Matsuda, Avtar K Singh, Inderjit Singh
Vaccine-induced Aβ-specific CD8+ T cells do not trigger autoimmune neuroinflammation in a murine model of Alzheimer’s disease
Martine Bruley Rosset, Gabrielle Lui, Cira Dansokho, Thomas Chaigneau, Guillaume Dorothée
Evidence for a distinct neuro-immune signature in rats that develop behavioural disability after nerve injury
Paul J Austin, Annika M Berglund, Sherman Siu, Nathan T Fiore, Michelle B Gerke-Duncan, Suzanne L Ollerenshaw, Sarah-Jane Leigh, Priya A Kunjan, James WM Kang, Kevin A Keay
Differential expression and clinical significance of three inflammation-related microRNAs in gangliogliomas
A. S. Prabowo, J. van Scheppingen, A. M. Iyer, J. J. Anink, W. G. M. Spliet, P. C. van Rijen, A. Y. N. Schouten-van Meeteren, E. Aronica
CXCR2 is essential for cerebral endothelial activation and leukocyte recruitment during neuroinflammation
Fengjiao Wu, Yawei Zhao, Tian Jiao, Dongyan Shi, Xingxing Zhu, Mingshun Zhang, Meiqing Shi, Hong Zhou
The role of PPAR activation during the systemic response to brain injury
Patrick Losey, Emma Ladds, Maud Laprais, Borna Geuvel, Laura Burns, Regis Bordet, Daniel C Anthony
TANK-binding kinase 1 (TBK1) modulates inflammatory hyperalgesia by regulating MAP kinases and NF-κB dependent genes
Christine V. Möser, Heike Stephan, Katharina Altenrath, Katharina L. Kynast, Otto Q. Russe, Katrin Olbrich, Gerd Geisslinger, Ellen Niederberger
The role of the prostaglandin E2 receptors in vulnerability of oligodendrocyte precursor cells to death
Noel G. Carlson, Satya Bellamkonda, Linda Schmidt, Jonathan Redd, Thomas Huecksteadt, Lauren Marissa Weber, Ethan Davis, Blair Wood, Takayuki Maruyama, John W. Rose
Heat stress-induced memory impairment is associated with neuroinflammation in mice
Wonil Lee, Minho Moon, Hyo Geun Kim, Tae Hee Lee, Myung Sook Oh
Electroacupuncture remediates glial dysfunction and ameliorates neurodegeneration in the astrocytic α-synuclein mutant mouse model
Jiahui Deng, E Lv, Jian Yang, Xiaoli Gong, Wenzhong Zhang, Xibin Liang, Jiazeng Wang, Jun Jia, Xiaomin Wang
Inhibition of NADPH oxidase activation reduces EAE-induced white matter damage in mice
Bo Young Choi, Jin Hee Kim, A Ra Kho, In Yeol Kim, Song Hee Lee, Bo Eun Lee, Eunhi Choi, Min Sohn, Mackenzie Stevenson, Tae Nyoung Chung, Tiina M Kauppinen, Sang Won Suh
Sensitivity of spiral ganglion neurons to damage caused by mobile phone electromagnetic radiation will increase in lipopolysaccharide-induced inflammation in vitro model
Wen-Qi Zuo, Yu-Juan Hu, Yang Yang, Xue-Yan Zhao, Yuan-Yuan Zhang, Wen Kong, Wei-Jia Kong
Functional differences between microglia and monocytes after ischemic stroke
Rodney M. Ritzel, Anita R. Patel, Jeremy M. Grenier, Joshua Crapser, Rajkumar Verma, Evan R. Jellison, Louise D. McCullough
Immunoglobulins stimulate cultured Schwann cell maturation and promote their potential to induce axonal outgrowth
Nevena Tzekova, André Heinen, Sebastian Bunk, Corinna Hermann, Hans-Peter Hartung, Birgit Reipert, Patrick Küry
Mapping neuroinflammation in frontotemporal dementia with molecular PET imaging
Jing Zhang
Crosstalk between macrophages and astrocytes affects proliferation, reactive phenotype and inflammatory response, suggesting a role during reactive gliosis following spinal cord injury
Niels Haan, Bangfu Zhu, Jian Wang, Xiaoqing Wei, Bing Song
Activation of the kynurenine pathway and increased production of the excitotoxin quinolinic acid following traumatic brain injury in humans
Edwin B. Yan, Tony Frugier, Chai K. Lim, Benjamin Heng, Gayathri Sundaram, May Tan, Jeffrey V. Rosenfeld, David W. Walker, Gilles J. Guillemin, Maria Cristina Morganti-Kossmann
Neuronal self-injury mediated by IL-1β and MMP-9 in a cerebral palsy model of severe neonatal encephalopathy induced by immune activation plus hypoxia-ischemia
Alexandre Savard, Marie-Elsa Brochu, Mathilde Chevin, Clémence Guiraut, Djordje Grbic, Guillaume Sébire
Immunosuppressive potential of human amnion epithelial cells in the treatment of experimental autoimmune encephalomyelitis
Courtney A. McDonald, Natalie L. Payne, Guizhi Sun, Leon Moussa, Christopher Siatskas, Rebecca Lim, Euan M. Wallace, Graham Jenkin, Claude C.A. Bernard
Curcumin prophylaxis mitigates the incidence of hypobaric hypoxia-induced altered ion channels expression and impaired tight junction proteins integrity in rat brain
SKS Sarada, M Titto, P Himadri, S Saumya, V Vijayalakshmi
Systemic inflammation and microglial activation: systematic review of animal experiments
Inge C.M. Hoogland, Carin Houbolt, David J. van Westerloo, Willem A. van Gool, Diederik van de Beek
Adenosine A2AR blockade prevents neuroinflammation-induced death of retinal ganglion cells caused by elevated pressure
Maria H. Madeira, Filipe Elvas, Raquel Boia, Francisco Q. Gonçalves, Rodrigo A. Cunha, António Francisco Ambrósio, Ana Raquel Santiago
RETRACTED ARTICLE: Regulation of autophagy by the nuclear factor κB signaling pathway in the hippocampus of rats with sepsis
YunJie Su, Yi Qu, FengYan Zhao, HuaFeng Li, DeZhi Mu, XiHong Li
Recombinant human PDCD5 (rhPDCD5) protein is protective in a mouse model of multiple sclerosis
Juan Xiao, Wenwei Liu, Yingyu Chen, Wenbin Deng
Caspase-1 inhibitor ameliorates experimental autoimmune myasthenia gravis by innate dendric cell IL-1-IL-17 pathway
Cong-Cong Wang, Heng Li, Min Zhang, Xiao-Li Li, Long-Tao Yue, Peng Zhang, Yue Zhao, Shan Wang, Ruo-Nan Duan, Yan-Bin Li, Rui-Sheng Duan
Interleukin-22 is increased in multiple sclerosis patients and targets astrocytes
Guillaume Perriard, Amandine Mathias, Lukas Enz, Mathieu Canales, Myriam Schluep, Melanie Gentner, Nicole Schaeren-Wiemers, Renaud A. Du Pasquier
Chronic morphine and HIV-1 Tat promote differential central nervous system trafficking of CD3+ and Ly6C+ immune cells in a murine Streptococcus pneumoniae infection model
Raini Dutta, Sabita Roy
Age-related increases in amyloid beta and membrane attack complex: evidence of inflammasome activation in the rodent eye
Tom Zhao, Jiangyuan Gao, Jenifer Van, Eleanor To, Aikun Wang, Sijia Cao, Jing Z. Cui, Jian-Ping Guo, Moonhee Lee, Patrick L. McGeer, Joanne A. Matsubara
Cu(II) enhances the effect of Alzheimer’s amyloid-β peptide on microglial activation
Fengxiang Yu, Ping Gong, Zhuqin Hu, Yu Qiu, Yongyao Cui, Xiaoling Gao, Hongzhuan Chen, Juan Li
HLA-DRα1-mMOG-35-55 treatment of experimental autoimmune encephalomyelitis reduces CNS inflammation, enhances M2 macrophage frequency, and promotes neuroprotection
Gil Benedek, Roberto Meza-Romero, Kelley Jordan, Lucy Keenlyside, Halina Offner, Arthur A. Vandenbark
Bee venom ameliorates lipopolysaccharide-induced memory loss by preventing NF-kappaB pathway
Sun Mi Gu, Mi Hee Park, Chul Ju Hwang, Ho Sueb Song, Ung Soo Lee, Sang Bae Han, Ki Wan Oh, Young Wan Ham, Min Jong Song, Dong Ju Son, Jin Tae Hong
TNF-dependent regulation and activation of innate immune cells are essential for host protection against cerebral tuberculosis
Ngiambudulu M. Francisco, Nai-Jen Hsu, Roanne Keeton, Philippa Randall, Boipelo Sebesho, Nasiema Allie, Dhirendra Govender, Valerie Quesniaux, Bernhard Ryffel, Lauriston Kellaway, Muazzam Jacobs
Tumor necrosis factor-α enhances voltage-gated Na+ currents in primary culture of mouse cortical neurons
Weiqiang Chen, Jiangtao Sheng, Jingfang Guo, Fenfei Gao, Xiangfeng Zhao, Jianping Dai, Gefei Wang, Kangsheng Li
Humoral factors in ALS patients during disease progression
Jared Ehrhart, Adam J. Smith, Nicole Kuzmin-Nichols, Theresa A. Zesiewicz, Israt Jahan, R. Douglas Shytle, Seol-Hee Kim, Cyndy D. Sanberg, Tuan H. Vu, Clifton L. Gooch, Paul R. Sanberg, Svitlana Garbuzova-Davis
STAT4 controls GM-CSF production by both Th1 and Th17 cells during EAE
Ian L. McWilliams, Rajani Rajbhandari, Susan Nozell, Etty Benveniste, Laurie E. Harrington
Increased CCL2, CCL3, CCL5, and IL-1β cytokine concentration in piriform cortex, hippocampus, and neocortex after pilocarpine-induced seizures
Gabriel M. Arisi, Maira L. Foresti, Khurshed Katki, Lee A. Shapiro
Transcript analysis of laser capture microdissected white matter astrocytes and higher phenol sulfotransferase 1A1 expression during autoimmune neuroinflammation
Flora Guillot, Alexandra Garcia, Marion Salou, Sophie Brouard, David A. Laplaud, Arnaud B. Nicot
Pro-inflammatory TNFα and IL-1β differentially regulate the inflammatory phenotype of brain microvascular endothelial cells
Simon J. O’Carroll, Dan Ting Kho, Rachael Wiltshire, Vicky Nelson, Odunayo Rotimi, Rebecca Johnson, Catherine E. Angel, E. Scott Graham
Immune and Epstein-Barr virus gene expression in cerebrospinal fluid and peripheral blood mononuclear cells from patients with relapsing-remitting multiple sclerosis
Caterina Veroni, Fabiana Marnetto, Letizia Granieri, Antonio Bertolotto, Clara Ballerini, Anna Maria Repice, Lucia Schirru, Giancarlo Coghe, Eleonora Cocco, Eleni Anastasiadou, Maria Puopolo, Francesca Aloisi
β-Lapachone suppresses neuroinflammation by modulating the expression of cytokines and matrix metalloproteinases in activated microglia
Eun-Jung Lee, Hyun-Myung Ko, Yeon-Hui Jeong, Eun-Mi Park, Hee-Sun Kim
Evidence for the involvement of gamma delta T cells in the immune response in Rasmussen encephalitis
Geoffrey C. Owens, Kate L. Erickson, Colin C. Malone, Calvin Pan, My N. Huynh, Julia W. Chang, Thabiso Chirwa, Harry V. Vinters, Gary W. Mathern, Carol A. Kruse
Pathogenesis of intracranial aneurysm is mediated by proinflammatory cytokine TNFA and IFNG and through stochastic regulation of IL10 and TGFB1 by comorbid factors
Sanish Sathyan, Linda V. Koshy, Lekshmi Srinivas, H. V. Easwer, S. Premkumar, Suresh Nair, R. N. Bhattacharya, Jacob P. Alapatt, Moinak Banerjee
Inhibition of NOX1/4 with GKT137831: a potential novel treatment to attenuate neuroglial cell inflammation in the retina
Devy Deliyanti, Jennifer L. Wilkinson-Berka
HMGB1 promotes the activation of NLRP3 and caspase-8 inflammasomes via NF-κB pathway in acute glaucoma
Wei Chi, Hongrui Chen, Fei Li, Yingting Zhu, Wei Yin, Yehong Zhuo
Voluntary exercise attenuates LPS-induced reductions in neurogenesis and increases microglia expression of a proneurogenic phenotype in aged mice
Alyssa M. Littlefield, Sharay E. Setti, Carolina Priester, Rachel A. Kohman
Colony-stimulating factor 1 receptor inhibition prevents microglial plaque association and improves cognition in 3xTg-AD mice
Nabil N. Dagher, Allison R. Najafi, Kara M. Neely Kayala, Monica R. P. Elmore, Terra E. White, Rodrigo Medeiros, Brian L. West, Kim N. Green
Prolonged diet-induced obesity in mice modifies the inflammatory response and leads to worse outcome after stroke
Samaneh Maysami, Michael J. Haley, Natalia Gorenkova, Siddharth Krishnan, Barry W McColl, Catherine B Lawrence
Neuroinflammatory responses in diabetic retinopathy
Ying Yu, Hui Chen, Shao Bo Su
Erratum to: Insulin improves memory and reduces chronic neuroinflammation in the hippocampus of young but not aged brains
Linda Adzovic, Ashley E Lynn, Heather M D’Angelo, Alexis M Crockett, Roxanne M Kaercher, Sarah E Royer, Sarah C Hopp, Gary L Wenk
Nlrp6 promotes recovery after peripheral nerve injury independently of inflammasomes
Elke Ydens, Dieter Demon, Guillaume Lornet, Vicky De Winter, Vincent Timmerman, Mohamed Lamkanfi, Sophie Janssens
Pharmacological antagonism of interleukin-8 receptor CXCR2 inhibits inflammatory reactivity and is neuroprotective in an animal model of Alzheimer’s disease
Jae K Ryu, T Cho, Hyun B Choi, N Jantaratnotai, James G McLarnon
CD300f immunoreceptor contributes to peripheral nerve regeneration by the modulation of macrophage inflammatory phenotype
Hugo Peluffo, Patricia Solari-Saquieres, Maria Luciana Negro-Demontel, Isaac Francos-Quijorna, Xavier Navarro, Ruben López-Vales, Joan Sayós, Natalia Lago
Natalizumab treatment reduces L-selectin (CD62L) in CD4+ T cells
Michela Spadaro, Marzia Caldano, Fabiana Marnetto, Alessandra Lugaresi, Antonio Bertolotto
1,25-Dihydroxyvitamin D3 attenuates endotoxin-induced production of inflammatory mediators by inhibiting MAPK activation in primary cortical neuron-glia cultures
Ya-Ni Huang, Yi-Jung Ho, Chien-Cheng Lai, Chien-Tsai Chiu, Jia-Yi Wang
Chronic inflammatory demyelinating polyneuropathy (CIDP): change of serum IgG dimer levels during treatment with intravenous immunoglobulins
Christian Ritter, Ilja Bobylev, Helmar C. Lehmann
Adjuvant treatment with dexamethasone plus anti-C5 antibodies improves outcome of experimental pneumococcal meningitis: a randomized controlled trial
E. Soemirien Kasanmoentalib, Mercedes Valls Seron, B. Paul Morgan, Matthijs C. Brouwer, Diederik van de Beek
Active immunization against complement factor C5a: a new therapeutic approach for Alzheimer’s disease
Christine Landlinger, Lisa Oberleitner, Petra Gruber, Birgit Noiges, Kristyna Yatsyk, Radmila Santic, Markus Mandler, Guenther Staffler
Endogenous BDNF augments NMDA receptor phosphorylation in the spinal cord via PLCγ, PKC, and PI3K/Akt pathways during colitis
Miao Liu, Jarren C Kay, Shanwei Shen, Li-Ya Qiao
The disruption of mitochondrial axonal transport is an early event in neuroinflammation
Oihana Errea, Beatriz Moreno, Alba Gonzalez-Franquesa, Pablo M. Garcia-Roves, Pablo Villoslada
An N-terminal antibody promotes the transformation of amyloid fibrils into oligomers and enhances the neurotoxicity of amyloid-beta: the dust-raising effect
Yu-Hui Liu, Xian-Le Bu, Chun-Rong Liang, Ye-Ran Wang, Tao Zhang, Shu-Sheng Jiao, Fan Zeng, Xiu-Qing Yao, Hua-Dong Zhou, Juan Deng, Yan-Jiang Wang
Time-dependent effects of CX3CR1 in a mouse model of mild traumatic brain injury
Heidi Y. Febinger, Hannah E. Thomasy, Maria N. Pavlova, Kristyn M. Ringgold, Paulien R. Barf, Amrita M. George, Jenna N. Grillo, Adam D. Bachstetter, Jenny A. Garcia, Astrid E. Cardona, Mark R. Opp, Carmelina Gemma
Osthole confers neuroprotection against cortical stab wound injury and attenuates secondary brain injury
Yang Xia, Liang Kong, Yingjia Yao, Yanan Jiao, Jie Song, Zhenyu Tao, Zhong You, Jingxian Yang
Role of high-mobility group box 1 in methamphetamine-induced activation and migration of astrocytes
Yuan Zhang, Tiebing Zhu, Xiaotian Zhang, Jie Chao, Gang Hu, Honghong Yao
Granzyme B-inhibitor serpina3n induces neuroprotection in vitro and in vivo
Yohannes Haile, Katia Carmine-Simmen, Camille Olechowski, Bradley Kerr, R. Chris Bleackley, Fabrizio Giuliani
The alternatively spliced fibronectin CS1 isoform regulates IL-17A levels and mechanical allodynia after peripheral nerve injury
Huaqing Liu, Jennifer Dolkas, Khan Hoang, Mila Angert, Andrei V. Chernov, Albert G. Remacle, Sergey A. Shiryaev, Alex Y. Strongin, Tasuku Nishihara, Veronica I. Shubayev
miRNAs and SAMHD1 regulation in vitro and in a model of HIV CNS disease
Kenneth W. Witwer, Erin L. Buchanan, Stephanie L. Myers, Melissa A. McAlexander
Exposure of neonatal rats to alcohol has differential effects on neuroinflammation and neuronal survival in the cerebellum and hippocampus
Lauren A. Topper, Brian C. Baculis, C. Fernando Valenzuela
NG2-proteoglycan-dependent contributions of oligodendrocyte progenitors and myeloid cells to myelin damage and repair
Karolina Kucharova, William B. Stallcup
Deep brain stimulation induces antiapoptotic and anti-inflammatory effects in epileptic rats
Beatriz O. Amorim, Luciene Covolan, Elenn Ferreira, José Geraldo Brito, Diego P. Nunes, David G. de Morais, José N. Nobrega, Antonio M. Rodrigues, Antonio Carlos G. deAlmeida, Clement Hamani
Behavioural and neurobiological consequences of macrophage migration inhibitory factor gene deletion in mice
Cecilie Bay-Richter, Shorena Janelidze, Analise Sauro, Richard Bucala, Jack Lipton, Tomas Deierborg, Lena Brundin
Erratum to: Pathogenesis of intracranial aneurysm is mediated by proinflammatory cytokine TNFA and IFNG and through stochastic regulation of IL10 and TGFB1 by comorbid factors
Sanish Sathyan, Linda V. Koshy, Lekshmy Srinivas, H. V. Easwer, S. Premkumar, Suresh Nair, R. N. Bhattacharya, Jacob P. Alapatt, Moinak Banerjee
IL-17A is implicated in lipopolysaccharide-induced neuroinflammation and cognitive impairment in aged rats via microglial activation
Jie Sun, Susu Zhang, Xiang Zhang, Xiaobao Zhang, Hongquan Dong, Yanning Qian
Immune profile of an atypical EAE model in marmoset monkeys immunized with recombinant human myelin oligodendrocyte glycoprotein in incomplete Freund’s adjuvant
S. Anwar Jagessar, Nicole Heijmans, Erwin L A Blezer, Jan Bauer, Robert Weissert, Bert A. ‘t Hart
Mast cells in meningiomas and brain inflammation
Stavros Polyzoidis, Triantafyllia Koletsa, Smaro Panagiotidou, Keyoumars Ashkan, Theoharis C. Theoharides
Lack of neuroinflammation in the HIV-1 transgenic rat: an [18F]-DPA714 PET imaging study
Dianne E. Lee, Xuyi Yue, Wael G. Ibrahim, Margaret R. Lentz, Kristin L. Peterson, Elaine M. Jagoda, Michael Kassiou, Dragan Maric, William C. Reid, Dima A. Hammoud
Inhibition of NOX2 reduces locomotor impairment, inflammation, and oxidative stress after spinal cord injury
Guzal Khayrullina, Sara Bermudez, Kimberly R. Byrnes
Interleukin-36γ is expressed by neutrophils and can activate microglia, but has no role in experimental autoimmune encephalomyelitis
Lusine Bozoyan, Aline Dumas, Alexandre Patenaude, Luc Vallières
NT-020 treatment reduces inflammation and augments Nrf-2 and Wnt signaling in aged rats
Antwoine Flowers, Jea-Young Lee, Sandra Acosta, Charles Hudson, Brent Small, Cyndy D. Sanberg, Paula C. Bickford, Bethany Grimmig
Acute hemorrhagic leukoencephalitis (Weston-Hurst syndrome) in a patient with relapse-remitting multiple sclerosis
Özlem Yildiz, Refik Pul, Peter Raab, Christian Hartmann, Thomas Skripuletz, Martin Stangel
Early pro-inflammatory cytokine elevations in the DBA/2J mouse model of glaucoma
Gina N. Wilson, Denise M. Inman, Christine M. Dengler-Crish, Matthew A. Smith, Samuel D. Crish
Deficiency of macrophage migration inhibitory factor attenuates tau hyperphosphorylation in mouse models of Alzheimer’s disease
Shu-Qin Li, Yang Yu, Jin-Zhao Han, Ding Wang, Jin Liu, Feng Qian, Guo-Huang Fan, Richard Bucala, Richard D. Ye
Induction of virus-specific effector immune cell response limits virus replication and severe disease in mice infected with non-lethal West Nile virus Eg101 strain
Mukesh Kumar, Kelsey Roe, Maile O’Connell, Vivek R. Nerurkar
HMGB1 release triggered by the interaction of live retinal cells and uveitogenic T cells is Fas/FasL activation-dependent
Guomin Jiang, Yunsong Wang, Juan Yun, Amir Reza Hajrasouliha, Yuan Zhao, Deming Sun, Henry J Kaplan, Hui Shao
New means to assess neonatal inflammatory brain injury
Chen Jin, Irene Londono, Carina Mallard, Gregory A. Lodygensky
Adult autologous mesenchymal stem cells for the treatment of suspected non-infectious inflammatory diseases of the canine central nervous system: safety, feasibility and preliminary clinical findings
Offer Zeira, Nimrod Asiag, Marina Aralla, Erica Ghezzi, Letizia Pettinari, Laura Martinelli, Daniele Zahirpour, Maria Pia Dumas, Davide Lupi, Simone Scaccia, Martin Konar, Carlo Cantile
Sepsis-induced selective parvalbumin interneuron phenotype loss and cognitive impairments may be mediated by NADPH oxidase 2 activation in mice
Mu-Huo Ji, Li-Li Qiu, Hui Tang, Ling-Sha Ju, Xiao-Ru Sun, Hui Zhang, Min Jia, Zhi-Yi Zuo, Jin-Chun Shen, Jian-Jun Yang
The expression levels of prolyl oligopeptidase responds not only to neuroinflammation but also to systemic inflammation upon liver failure in rat models and cirrhotic patients
Jofre Tenorio-Laranga, Carmina Montoliu, Amparo Urios, Vicente Hernandez-Rabaza, Hanan Ahabrach, J. Arturo García-Horsman, Vicente Felipo
Fingolimod induces neuroprotective factors in human astrocytes
Franziska S. Hoffmann, Johann Hofereiter, Heike Rübsamen, Johannes Melms, Sigrid Schwarz, Hans Faber, Peter Weber, Benno Pütz, Verena Loleit, Frank Weber, Reinhard Hohlfeld, Edgar Meinl, Markus Krumbholz
NFκB signaling drives pro-granulocytic astroglial responses to neuromyelitis optica patient IgG
Margaret E. Walker-Caulfield, Yong Guo, Renee K. Johnson, Christina B. McCarthy, Patrick D. Fitz-Gibbon, Claudia F. Lucchinetti, Charles L. Howe
Microglia processes associate with diffusely injured axons following mild traumatic brain injury in the micro pig
Audrey D. Lafrenaye, Masaki Todani, Susan A. Walker, John T. Povlishock
Role of glial 14-3-3 gamma protein in autoimmune demyelination
De-Hyung Lee, Petra Steinacker, Silvia Seubert, Tanja Turnescu, Arthur Melms, Arndt Manzel, Markus Otto, Ralf A. Linker
Expression pattern of Ccr2 and Cx3cr1 in inherited retinal degeneration
Hideo Kohno, Hideto Koso, Kiichiro Okano, Thomas R. Sundermeier, Saburo Saito, Sumiko Watanabe, Hiroshi Tsuneoka, Tsutomu Sakai
Requirement for endogenous heat shock factor 1 in inducible nitric oxide synthase induction in murine microglia
Chao Huang, Xu Lu, Lijuan Tong, Jili Wang, Wei Zhang, Bo Jiang, Rongrong Yang
P2X7R blockade prevents NLRP3 inflammasome activation and brain injury in a rat model of intracerebral hemorrhage: involvement of peroxynitrite
Liang Feng, Yizhao Chen, Rui Ding, Zhenghao Fu, Shuo Yang, Xinqing Deng, Jun Zeng
Erratum To: Early pro-inflammatory cytokine elevations in the DBA/2J mouse model of glaucoma
Gina N. Wilson, Denise M. Inman, Christine M. Dengler-Crish, Matthew A. Smith, Samuel D. Crish
Complement receptor 2 is up regulated in the spinal cord following nerve root injury and modulates the spinal cord response
Rickard P. F. Lindblom, Alexander Berg, Mikael Ström, Shahin Aeinehband, Cecilia A. Dominguez, Faiez Al Nimer, Nada Abdelmagid, Matthias Heinig, Johan Zelano, Karin Harnesk, Norbert Hübner, Bo Nilsson, Kristina Nilsson Ekdahl, Margarita Diez, Staffan Cullheim, Fredrik Piehl
Suppression of MAPK attenuates neuronal cell death induced by activated glia-conditioned medium in alpha-synuclein overexpressing SH-SY5Y cells
Lidia M. Yshii, Alexandre Denadai-Souza, Andrea R. Vasconcelos, Maria Christina W. Avellar, Cristoforo Scavone
MOG-induced experimental autoimmune encephalomyelitis in the rat species triggers anti-neurofascin antibody response that is genetically regulated
Sevasti Flytzani, Andre Ortlieb Guerreiro-Cacais, Marie N’diaye, Maren Lindner, Christopher Linington, Edgar Meinl, Pernilla Stridh, Maja Jagodic, Tomas Olsson
Sildenafil reduces neuroinflammation and restores spatial learning in rats with hepatic encephalopathy: underlying mechanisms
Vicente Hernandez-Rabaza, Ana Agusti, Andrea Cabrera-Pastor, Santos Fustero, Oscar Delgado, Lucas Taoro-Gonzalez, Carmina Montoliu, Marta Llansola, Vicente Felipo
Next-generation sequencing identifies altered whole blood microRNAs in neuromyelitis optica spectrum disorder which may permit discrimination from multiple sclerosis
Andreas Keller, Petra Leidinger, Eckart Meese, Jan Haas, Christina Backes, Ludwig Rasche, Janina R. Behrens, Catherina Pfuhl, Katharina Wakonig, René M. Gieß, Sven Jarius, Benjamin Meder, Judith Bellmann-Strobl, Friedemann Paul, Florence C. Pache, Klemens Ruprecht
IL-4/10 prevents stress vulnerability following imipramine discontinuation
Arum Han, Hyelim Yeo, Min-Jung Park, Seung Hyun Kim, Hyun Jin Choi, Chang-Won Hong, Min-Soo Kwon
The nod-like receptor, Nlrp12, plays an anti-inflammatory role in experimental autoimmune encephalomyelitis
Marjan Gharagozloo, Tara M. Mahvelati, Emilie Imbeault, Pavel Gris, Echarki Zerif, Diwakar Bobbala, Subburaj Ilangumaran, Abdelaziz Amrani, Denis Gris
Cytosolic phospholipase A2 plays a crucial role in ROS/NO signaling during microglial activation through the lipoxygenase pathway
Dennis Y. Chuang, Agnes Simonyi, Paul T. Kotzbauer, Zezong Gu, Grace Y. Sun
Decreased progranulin levels in patients and rats with subarachnoid hemorrhage: a potential role in inhibiting inflammation by suppressing neutrophil recruitment
Chenhui Zhou, Guangbin Xie, Chunxi Wang, Zihuan Zhang, Qiang Chen, Li Zhang, Lingyun Wu, Yongxiang Wei, Hui Ding, Chunhua Hang, Mengliang Zhou, Jixin Shi
Targeting translocator protein (18 kDa) (TSPO) dampens pro-inflammatory microglia reactivity in the retina and protects from degeneration
Rebecca Scholz, Albert Caramoy, Mohajeet B. Bhuckory, Khalid Rashid, Mei Chen, Heping Xu, Christian Grimm, Thomas Langmann
Altered morphological dynamics of activated microglia after induction of status epilepticus
Elena Avignone, Marilyn Lepleux, Julie Angibaud, U. Valentin Nägerl
Arginase 1+ microglia reduce Aβ plaque deposition during IL-1β-dependent neuroinflammation
Jonathan D. Cherry, John A. Olschowka, M. Kerry O’Banion
Targeting inflammation to influence mood following spinal cord injury: a randomized clinical trial
David J. Allison, David S. Ditor
Neuropsychiatric systemic lupus erythematosus persists despite attenuation of systemic disease in MRL/lpr mice
Ariel D. Stock, Jing Wen, Jessica Doerner, Leal C. Herlitz, Maria Gulinello, Chaim Putterman
MicroRNA367 negatively regulates the inflammatory response of microglia by targeting IRAK4 in intracerebral hemorrhage
Bangqing Yuan, Hanchao Shen, Li Lin, Tonggang Su, Lina Zhong, Zhao Yang
Self-reactive CD4+ T cells activated during viral-induced demyelination do not prevent clinical recovery
Carine Savarin, Cornelia C. Bergmann, Melanie Gaignage, Stephen A. Stohlman
Minocycline counter-regulates pro-inflammatory microglia responses in the retina and protects from degeneration
Rebecca Scholz, Markus Sobotka, Albert Caramoy, Thomas Stempfl, Christoph Moehle, Thomas Langmann
Silencing of Abcc8 or inhibition of newly upregulated Sur1-Trpm4 reduce inflammation and disease progression in experimental autoimmune encephalomyelitis
Tapas K. Makar, Volodymyr Gerzanich, Vamshi K.C. Nimmagadda, Rupal Jain, Kristal Lam, Fahad Mubariz, David Trisler, Svetlana Ivanova, Seung Kyoon Woo, Min Seong Kwon, Joseph Bryan, Christopher T. Bever, J. Marc Simard
Endogenous IFN-β signaling exerts anti-inflammatory actions in experimentally induced focal cerebral ischemia
Ana R. Inácio, Yawei Liu, Bettina H. Clausen, Martina Svensson, Krzysztof Kucharz, Yiyi Yang, Totte Stankovich, Reza Khorooshi, Kate L. Lambertsen, Shohreh Issazadeh-Navikas, Tomas Deierborg
PKR deficiency alters E. coli-induced sickness behaviors but does not exacerbate neuroimmune responses or bacterial load
David Chun-Hei Poon, Yuen-Shan Ho, Ran You, Hei-Long Tse, Kin Chiu, Raymond Chuen-Chung Chang
Erratum to: A role for human brain pericytes in neuroinflammation
Deidre Jansson, Justin Rustenhoven, Sheryl Feng, Daniel Hurley, Robyn L. Oldfield, Peter S. Bergin, Edward W. Mee, Richard L. M. Faull, Mike Dragunow
Matrix-derived inflammatory mediator N-acetyl proline-glycine-proline is neurotoxic and upregulated in brain after ischemic stroke
Jeff W. Hill, Edwin M. Nemoto
Inflammation and neuronal death in the motor cortex of the wobbler mouse, an ALS animal model
Carolin Dahlke, Darius Saberi, Bastian Ott, Beate Brand-Saberi, Thomas Schmitt-John, Carsten Theiss
Amelioration of Japanese encephalitis by blockage of 4-1BB signaling is coupled to divergent enhancement of type I/II IFN responses and Ly-6Chi monocyte differentiation
Seong Bum Kim, Jin Young Choi, Jin Hyoung Kim, Erdenebelig Uyangaa, Ajit Mahadev Patil, Sang-Youel Park, John Hwa Lee, Koanhoi Kim, Young Woo Han, Seong Kug Eo
PET imaging studies show enhanced expression of mGluR5 and inflammatory response during progressive degeneration in ALS mouse model expressing SOD1-G93A gene
Anna-Liisa Brownell, Darshini Kuruppu, Kun-Eek Kil, Kimmo Jokivarsi, Pekka Poutiainen, Aijun Zhu, Michelle Maxwell
Azithromycin drives alternative macrophage activation and improves recovery and tissue sparing in contusion spinal cord injury
Bei Zhang, William M. Bailey, Timothy J. Kopper, Michael B. Orr, David J. Feola, John C. Gensel
SDF1–CXCR4 signaling contributes to persistent pain and hypersensitivity via regulating excitability of primary nociceptive neurons: involvement of ERK-dependent Nav1.8 up-regulation
Fei Yang, Wei Sun, Yan Yang, Yan Wang, Chun-Li Li, Han Fu, Xiao-Liang Wang, Fan Yang, Ting He, Jun Chen
Retraction Note: Chronic neuroinflammation and cognitive impairment following transient global cerebral ischemia: role of fractalkine/CX3CR1 signaling
Teresita L. Briones, Julie Woods, Magdalena Wadowska
Late prenatal immune activation causes hippocampal deficits in the absence of persistent inflammation across aging
Sandra Giovanoli, Tina Notter, Juliet Richetto, Marie A. Labouesse, Stéphanie Vuillermot, Marco A. Riva, Urs Meyer
Lipopolysaccharide-induced blood-brain barrier disruption: roles of cyclooxygenase, oxidative stress, neuroinflammation, and elements of the neurovascular unit
William A. Banks, Alicia M. Gray, Michelle A. Erickson, Therese S. Salameh, Mamatha Damodarasamy, Nader Sheibani, James S. Meabon, Emily E. Wing, Yoichi Morofuji, David G. Cook, May J. Reed
Thalamic inflammation after brain trauma is associated with thalamo-cortical white matter damage
Gregory Scott, Peter J. Hellyer, Anil F. Ramlackhansingh, David J. Brooks, Paul M. Matthews, David J. Sharp
Trazodone regulates neurotrophic/growth factors, mitogen-activated protein kinases and lactate release in human primary astrocytes
Simona Daniele, Elisa Zappelli, Claudia Martini
Low serum ficolin-3 levels are associated with severity and poor outcome in traumatic brain injury
Jian-Wei Pan, Xiong-Wei Gao, Hao Jiang, Ya-Feng Li, Feng Xiao, Ren-Ya Zhan
Epistasis analysis links immune cascades and cerebral amyloidosis
Andréa L. Benedet, Aurélie Labbe, Philippe Lemay, Eduardo R. Zimmer, Tharick A. Pascoal, Antoine Leuzy, Sulantha Mathotaarachchi, Sara Mohades, Monica Shin, Alexandre Dionne-Laporte, Thomas Beaudry, Cynthia Picard, Serge Gauthier, Judes Poirier, Guy Rouleau, Pedro Rosa-Neto
Ccr2 deletion dissociates cavity size and tau pathology after mild traumatic brain injury
Stefka Gyoneva, Daniel Kim, Atsuko Katsumoto, O. Nicole Kokiko-Cochran, Bruce T. Lamb, Richard M. Ransohoff
NF-κB transcriptional activation by TNFα requires phospholipase C, extracellular signal-regulated kinase 2 and poly(ADP-ribose) polymerase-1
Billy Vuong, Adam D. J. Hogan-Cann, Conrad C. Alano, Mackenzie Stevenson, Wai Yee Chan, Christopher M. Anderson, Raymond A. Swanson, Tiina M. Kauppinen
Leucine-rich repeat kinase 2 positively regulates inflammation and down-regulates NF-κB p50 signaling in cultured microglia cells
Isabella Russo, Giulia Berti, Nicoletta Plotegher, Greta Bernardo, Roberta Filograna, Luigi Bubacco, Elisa Greggio
Dental follicle mesenchymal stem cell administration ameliorates muscle weakness in MuSK-immunized mice
Canan Ulusoy, Noushin Zibandeh, Selin Yıldırım, Nikolaos Trakas, Paraskevi Zisimopoulou, Melike Küçükerden, Hatice Tașlı, Socrates Tzartos, Kamil Göker, Erdem Tüzün, Tunç Akkoç
Electroconvulsive seizures (ECS) do not prevent LPS-induced behavioral alterations and microglial activation
E. M. van Buel, F. J. Bosker, J. van Drunen, J. Strijker, W. Douwenga, H. C. Klein, U. L. M. Eisel
CCR5 limits cortical viral loads during West Nile virus infection of the central nervous system
Douglas M. Durrant, Brian P. Daniels, TracyJo Pasieka, Denise Dorsey, Robyn S. Klein
Investigation of sex-specific effects of apolipoprotein E on severity of EAE and MS
L. Schrewe, C. M. Lill, T. Liu, A. Salmen, L. A. Gerdes, L. Guillot-Noel, D. A. Akkad, P. Blaschke, C. Graetz, S. Hoffjan, A. Kroner, S. Demir, A. Böhme, P. Rieckmann, A. ElAli, N. Hagemann, D. M. Hermann, I. Cournu-Rebeix, F. Zipp, T. Kümpfel, M. Buttmann, U. K. Zettl, B. Fontaine, L. Bertram, R. Gold, A. Chan
Hypoestoxide reduces neuroinflammation and α-synuclein accumulation in a mouse model of Parkinson’s disease
Changyoun Kim, Emmanuel Ojo-Amaize, Brian Spencer, Edward Rockenstein, Michael Mante, Paula Desplats, Wolf Wrasidlo, Anthony Adame, Emeka Nchekwube, Olusola Oyemade, Joseph Okogun, Michael Chan, Howard Cottam, Eliezer Masliah
Pro-inflammatory pattern of IgG1 Fc glycosylation in multiple sclerosis cerebrospinal fluid
Manfred Wuhrer, Maurice H. J. Selman, Liam A. McDonnell, Tania Kümpfel, Tobias Derfuss, Mohsen Khademi, Tomas Olsson, Reinhard Hohlfeld, Edgar Meinl, Markus Krumbholz
Loss of intraepidermal nerve fiber density during SIV peripheral neuropathy is mediated by monocyte activation and elevated monocyte chemotactic proteins
Jessica R. Lakritz, Jake A. Robinson, Michael J. Polydefkis, Andrew D. Miller, Tricia H. Burdo
Progesterone treatment reduces neuroinflammation, oxidative stress and brain damage and improves long-term outcomes in a rat model of repeated mild traumatic brain injury
Kyria M. Webster, David K. Wright, Mujun Sun, Bridgette D. Semple, Ezgi Ozturk, Donald G. Stein, Terence J. O’Brien, Sandy R. Shultz
Monomethyl fumarate promotes Nrf2-dependent neuroprotection in retinal ischemia-reperfusion
Hongkwan Cho, Matthew J. Hartsock, Zhenhua Xu, Meihua He, Elia J. Duh
Anti-inflammatory effects of dexamethasone and meloxicam on Borrelia burgdorferi-induced inflammation in neuronal cultures of dorsal root ganglia and myelinating cells of the peripheral nervous system
Geeta Ramesh, Olivia C. Meisner, Mario T. Philipp
Multipotent adult progenitor cells for hypoxic-ischemic injury in the preterm brain
Reint K. Jellema, Daan R. M. G Ophelders, Alex Zwanenburg, Maria Nikiforou, Tammo Delhaas, Peter Andriessen, Robert W. Mays, Robert Deans, Wilfred T. V. Germeraad, Tim G. A. M. Wolfs, Boris W. Kramer
Interferon-stimulated genes—essential antiviral effectors implicated in resistance to Theiler’s virus-induced demyelinating disease
Lin Li, Reiner Ulrich, Wolfgang Baumgärtner, Ingo Gerhauser
Antagonist of the neurokinin-1 receptor curbs neuroinflammation in ex vivo and in vitro models of Lyme neuroborreliosis
Alejandra N. Martinez, Geeta Ramesh, Mary B. Jacobs, Mario T. Philipp
Ligand engagement of Toll-like receptors regulates their expression in cortical microglia and astrocytes
Carla Marinelli, Rosa Di Liddo, Laura Facci, Thomas Bertalot, Maria Teresa Conconi, Morena Zusso, Stephen D. Skaper, Pietro Giusti
Identification of a novel mechanism of action of fingolimod (FTY720) on human effector T cell function through TCF-1 upregulation
Maria Antonietta Mazzola, Radhika Raheja, Gopal Murugaiyan, Hasan Rajabi, Deepak Kumar, Thomas Pertel, Keren Regev, Russell Griffin, Lilian Aly, Pia Kivisakk, Parham Nejad, Bonny Patel, Nguendab Gwanyalla, Hillary Hei, Bonnie Glanz, Tanuja Chitnis, Howard L. Weiner, Roopali Gandhi
Acid-sensing ion channel 1a contributes to the effect of extracellular acidosis on NLRP1 inflammasome activation in cortical neurons
Yu-Chan Wang, Wei-Zu Li, Yu Wu, Yan-Yan Yin, Liu-Yi Dong, Zhi-Wu Chen, Wen-Ning Wu
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