Ausgabe 1/2021
Inhalt (172 Artikel)
Correction to: circRIP2 accelerates bladder cancer progression via miR-1305/Tgf-β2/smad3 pathway
Yinjie Su, Weilian Feng, Juanyi Shi, Luping Chen, Jian Huang, Tianxin Lin
Cytokine-chemokine network driven metastasis in esophageal cancer; promising avenue for targeted therapy
Ajaz A. Bhat, Sabah Nisar, Selma Maacha, Tatiana Correa Carneiro-Lobo, Sabah Akhtar, Kodappully Sivaraman Siveen, Nissar A. Wani, Arshi Rizwan, Puneet Bagga, Mayank Singh, Ravinder Reddy, Shahab Uddin, Jean-Charles Grivel, Gyan Chand, Michael P. Frenneaux, Mushtaq A. Siddiqi, Davide Bedognetti, Wael El-Rifai, Muzafar A. Macha, Mohammad Haris
Taking the Myc out of cancer: toward therapeutic strategies to directly inhibit c-Myc
Sarah K. Madden, Aline Dantas de Araujo, Mara Gerhardt, David P. Fairlie, Jody M. Mason
Expression profiles, biological functions and clinical significance of circRNAs in bladder cancer
Xiaoqi Yang, Tao Ye, Haoran Liu, Peng Lv, Chen Duan, Xiaoliang Wu, Kehua Jiang, Hongyan Lu, Ding Xia, Ejun Peng, Zhiqiang Chen, Kun Tang, Zhangqun Ye
Targeting CDK7 suppresses super enhancer-linked inflammatory genes and alleviates CAR T cell-induced cytokine release syndrome
Ye Wei, Chong Li, Huifang Bian, Wei Qian, Kairui Jin, Tingting Xu, Xiaomao Guo, Xueguan Lu, Fengtao Su
LncRNA CRNDE attenuates chemoresistance in gastric cancer via SRSF6-regulated alternative splicing of PICALM
Feifei Zhang, Hui Wang, Jiang Yu, Xueqing Yao, Shibin Yang, Weidong Li, Lijun Xu, Liang Zhao
Mechanisms of vasculogenic mimicry in hypoxic tumor microenvironments
Xiaoxu Wei, Yunhua Chen, Xianjie Jiang, Miao Peng, Yiduo Liu, Yongzhen Mo, Daixi Ren, Yuze Hua, Boyao Yu, Yujuan Zhou, Qianjin Liao, Hui Wang, Bo Xiang, Ming Zhou, Xiaoling Li, Guiyuan Li, Yong Li, Wei Xiong, Zhaoyang Zeng
Bone marrow infiltrated natural killer cells predicted the anti-leukemia activity of MCL1 or BCL2 inhibitors in acute myeloid leukemia
Yu-Jun Dai, Si-Yuan He, Fang Hu, Xue-Ping Li, Jian-Ming Zhang, Si-Liang Chen, Wei-Na Zhang, Hai-Min Sun, Da-Wei Wang
Hypoxia downregulated miR-4521 suppresses gastric carcinoma progression through regulation of IGF2 and FOXM1
Shan Xing, Zhi Tian, Wenying Zheng, Wenjuan Yang, Nan Du, Yixue Gu, Jiang Yin, Hao Liu, Xiaoting Jia, Donglan Huang, Wanli Liu, Min Deng
Two nanoformulations induce reactive oxygen species and immunogenetic cell death for synergistic chemo-immunotherapy eradicating colorectal cancer and hepatocellular carcinoma
Jianfeng Guo, Zhuo Yu, Dandan Sun, Yifang Zou, Yun Liu, Leaf Huang
A comparability study of natural and deglycosylated PD-L1 levels in lung cancer: evidence from immunohistochemical analysis
Jie Mei, Junying Xu, Xuejing Yang, Dingyi Gu, Weijian Zhou, Huiyu Wang, Chaoying Liu
ITGBL1 is a new immunomodulator that favors development of melanoma tumors by inhibiting natural killer cells cytotoxicity
Yann Cheli, Meri K. Tulic, Najla El Hachem, Nicolas Nottet, Arnaud Jacquel, Maeva Gesson, Thomas Strub, Karine Bille, Alexandra Picard-Gauci, Henri Montaudié, Guillaume E. Beranger, Thierry Passeron, Pierre Close, Corine Bertolotto, Robert Ballotti
Circular RNAs in body fluids as cancer biomarkers: the new frontier of liquid biopsies
Sumeng Wang, Ke Zhang, Shanyue Tan, Junyi Xin, Qianyu Yuan, Huanhuan Xu, Xian Xu, Qi Liang, David C. Christiani, Meilin Wang, Lingxiang Liu, Mulong Du
Unraveling tumour microenvironment heterogeneity in nasopharyngeal carcinoma identifies biologically distinct immune subtypes predicting prognosis and immunotherapy responses
Yu-Pei Chen, Jia-Wei Lv, Yan-Ping Mao, Xiao-Min Li, Jun-Yan Li, Ya-Qin Wang, Cheng Xu, Ying-Qin Li, Qing-Mei He, Xiao-Jing Yang, Yuan Lei, Jia-Yi Shen, Ling-Long Tang, Lei Chen, Guan-Qun Zhou, Wen-Fei Li, Xiao-Jing Du, Rui Guo, Xu Liu, Yuan Zhang, Jing Zeng, Jing-Ping Yun, Ying Sun, Na Liu, Jun Ma
Targeting AURKA in Cancer: molecular mechanisms and opportunities for Cancer therapy
Ruijuan Du, Chuntian Huang, Kangdong Liu, Xiang Li, Zigang Dong
The inflammatory kinase IKKα phosphorylates and stabilizes c-Myc and enhances its activity
Bernhard Moser, Bernhard Hochreiter, José Basílio, Viola Gleitsmann, Anja Panhuber, Alan Pardo-Garcia, Bastian Hoesel, Manuel Salzmann, Ulrike Resch, Mamoona Noreen, Johannes A. Schmid
Intercellular transfer of exosomal wild type EGFR triggers osimertinib resistance in non-small cell lung cancer
Shaocong Wu, Min Luo, Kenneth K. W. To, Jianye Zhang, Chaoyue Su, Hong Zhang, Sainan An, Fang Wang, Da Chen, Liwu Fu
The role of m6A, m5C and Ψ RNA modifications in cancer: Novel therapeutic opportunities
Paz Nombela, Borja Miguel-López, Sandra Blanco
Circular RNA circSDHC serves as a sponge for miR-127-3p to promote the proliferation and metastasis of renal cell carcinoma via the CDKN3/E2F1 axis
Junjie Cen, Yanping Liang, Yong Huang, Yihui Pan, Guannan Shu, Zhousan Zheng, Xiaozhong Liao, Mi Zhou, Danlei Chen, Yong Fang, Wei Chen, Junhang Luo, Jiaxing Zhang
PARP inhibitor Olaparib overcomes Sorafenib resistance through reshaping the pluripotent transcriptome in hepatocellular carcinoma
Xiao-Dong Yang, Fan-En Kong, Ling Qi, Jia-Xin Lin, Qian Yan, Jane Ho Chun Loong, Shao-Yan Xi, Yue Zhao, Yan Zhang, Yun-Fei Yuan, Ning-Fang Ma, Stephanie Ma, Xin-Yuan Guan, Ming Liu
Correction to: ITGBL1 is a new immunomodulator that favors development of melanoma tumors by inhibiting natural killer cells cytotoxicity
Yann Cheli, Meri K. Tulic, Najla El Hachem, Nicolas Nottet, Arnaud Jacquel, Maeva Gesson, Thomas Strub, Karine Bille, Alexandra Picard-Gauci, Henri Montaudié, Guillaume E. Beranger, Thierry Passeron, Pierre Close, Corine Bertolotto, Robert Ballotti
Progress on pivotal role and application of exosome in lung cancer carcinogenesis, diagnosis, therapy and prognosis
Ming-Yue Li, Li-Zhong Liu, Ming Dong
Non-invasive lung cancer diagnosis and prognosis based on multi-analyte liquid biopsy
Kezhong Chen, Jianlong Sun, Heng Zhao, Ruijingfang Jiang, Jianchao Zheng, Zhilong Li, Jiaxi Peng, Haifeng Shen, Kai Zhang, Jin Zhao, Shida Zhu, Yuying Wang, Fan Yang, Jun Wang
Non-coding RNAs regulation of macrophage polarization in cancer
Swati Mohapatra, Carlotta Pioppini, Bulent Ozpolat, George A. Calin
CircNR3C2 promotes HRD1-mediated tumor-suppressive effect via sponging miR-513a-3p in triple-negative breast cancer
Ya Fan, Jia Wang, Wen Jin, Yifei Sun, Yuemei Xu, Yipin Wang, Xiubin Liang, Dongming Su
Comprehensive landscape and future perspectives of circular RNAs in colorectal cancer
Fei Long, Zhi Lin, Liang Li, Min Ma, Zhixing Lu, Liang Jing, Xiaorong Li, Changwei Lin
Chemotherapeutic and targeted agents can modulate the tumor microenvironment and increase the efficacy of immune checkpoint blockades
Jun-Yan Li, Yu-Pei Chen, Ying-Qin Li, Na Liu, Jun Ma
The cancer metabolic reprogramming and immune response
Longzheng Xia, Linda Oyang, Jinguan Lin, Shiming Tan, Yaqian Han, Nayiyuan Wu, Pin Yi, Lu Tang, Qing Pan, Shan Rao, Jiaxin Liang, Yanyan Tang, Min Su, Xia Luo, Yiqing Yang, Yingrui Shi, Hui Wang, Yujuan Zhou, Qianjin Liao
Cross-talk of four types of RNA modification writers defines tumor microenvironment and pharmacogenomic landscape in colorectal cancer
Huifang Chen, Jiameng Yao, Rujuan Bao, Yu Dong, Ting Zhang, Yanhua Du, Gaoyang Wang, Duan Ni, Zhenzhen Xun, Xiaoyin Niu, Youqiong Ye, Hua-Bing Li
Selective treatment pressure in colon cancer drives the molecular profile of resistant circulating tumor cell clones
Laure Cayrefourcq, Frédéric Thomas, Thibault Mazard, Eric Assenat, Said Assou, Catherine Alix-Panabières
Pan-cancer characterization of expression and clinical relevance of m6A-related tissue-elevated long non-coding RNAs
Kang Xu, Yangyang Cai, Mengying Zhang, Haozhe Zou, Zhenghong Chang, Donghao Li, Jing Bai, Juan Xu, Yongsheng Li
Nanopore sequencing from liquid biopsy: analysis of copy number variations from cell-free DNA of lung cancer patients
Filippo Martignano, Uday Munagala, Stefania Crucitta, Alessandra Mingrino, Roberto Semeraro, Marzia Del Re, Iacopo Petrini, Alberto Magi, Silvestro G. Conticello
mRNA vaccine: a potential therapeutic strategy
Yang Wang, Ziqi Zhang, Jingwen Luo, Xuejiao Han, Yuquan Wei, Xiawei Wei
Coupled liquid biopsy and bioinformatics for pancreatic cancer early detection and precision prognostication
Jun Hou, XueTao Li, Ke-Ping Xie
Correction to: Exosomes derived from gemcitabine resistant cells transfer malignant phenotypic traits via delivery of miRNA-222-3p
Feng Wei, Chengyuan Ma, Tong Zhou, Xuechao Dong, Qinghua Luo, Li Geng, Lijuan Ding, Yandong Zhang, Li Zhang, Nan Li, Yang Li, Yan Liu
Genome-wide cell-free DNA methylation analyses improve accuracy of non-invasive diagnostic imaging for early-stage breast cancer
Jiaqi Liu, Hengqiang Zhao, Yukuan Huang, Shouping Xu, Yan Zhou, Wei Zhang, Jiaqi Li, Yue Ming, Xinyu Wang, Sen Zhao, Kai Li, Xiying Dong, Yunlong Ma, Tianyi Qian, Xinyi Chen, Zeyu Xing, Yan Zhang, Hongyan Chen, Zhihua Liu, Da Pang, Meng Zhou, Zhihong Wu, Xiaowo Wang, Xiang Wang, Nan Wu, Jianzhong Su
Intratumoral heterogeneity as a predictive biomarker in anti-PD-(L)1 therapies for non-small cell lung cancer
Wenfeng Fang, Haoxuan Jin, Huaqiang Zhou, Shaodong Hong, Yuxiang Ma, Yaxiong Zhang, Xiaofan Su, Longyun Chen, Yunpeng Yang, Shengqiang Xu, Yuwei Liao, Yuming He, Hongyun Zhao, Yan Huang, Zhibo Gao, Li Zhang
DDX3X: structure, physiologic functions and cancer
Jie Mo, Huifang Liang, Chen Su, Pengcheng Li, Jin Chen, Bixiang Zhang
Liquid biopsy proteomics of uveal melanoma reveals biomarkers associated with metastatic risk
Gabriel Velez, Huy V. Nguyen, Teja Chemudupati, Cassie A. Ludwig, Marcus Toral, Sunil Reddy, Prithvi Mruthyunjaya, Vinit B. Mahajan
G-quadruplexes: a promising target for cancer therapy
Nils Kosiol, Stefan Juranek, Peter Brossart, Annkristin Heine, Katrin Paeschke
Correction to: A novel protein encoded by a circular RNA circPPP1R12A promotes tumor pathogenesis and metastasis of colon cancer via Hippo-YAP signaling
Xiao Zheng, Lujun Chen, You Zhou, Qi Wang, Zhuojun Zheng, Bin Xu, Chen Wu, Qi Zhou, Wenwei Hu, Changping Wu, Jingting Jiang
CircWAC induces chemotherapeutic resistance in triple-negative breast cancer by targeting miR-142, upregulating WWP1 and activating the PI3K/AKT pathway
Lei Wang, Yehui Zhou, Liang Jiang, Linlin Lu, Tiantian Dai, Aoshuang Li, Yan Chen, Lifeng Zhang
Identification of tumor antigens and immune subtypes of pancreatic adenocarcinoma for mRNA vaccine development
Xing Huang, Gang Zhang, Tianyu Tang, Tingbo Liang
FBW7 suppresses ovarian cancer development by targeting the N6-methyladenosine binding protein YTHDF2
Fei Xu, Jiajia Li, Mengdong Ni, Jingyi Cheng, Haiyun Zhao, Shanshan Wang, Xiang Zhou, Xiaohua Wu
Epigenetic silencing of miR-144/451a cluster contributes to HCC progression via paracrine HGF/MIF-mediated TAM remodeling
Junlong Zhao, Huichen Li, Shoujie Zhao, Enxin Wang, Jun Zhu, Dayun Feng, Yejing Zhu, Weijia Dou, Qingling Fan, Jie Hu, Lintao Jia, Lei Liu
Correction to: Salinomycin effectively eliminates cancer stem-like cells and obviates hepatic metastasis in uveal melanoma
Jingfeng Zhou, Shenglan Liu, Yun Wang, Wei Dai, Hailin Zou, Shubo Wang, Jing Zhang, Jingxuan Pan
mRNA in cancer immunotherapy: beyond a source of antigen
Lien Van Hoecke, Rein Verbeke, Heleen Dewitte, Ine Lentacker, Karim Vermaelen, Karine Breckpot, Sandra Van Lint
The role of mRNA in the development, diagnosis, treatment and prognosis of neural tumors
Yiyang Zheng, Yanyan Luo, Xixi Chen, Huiting Li, Baojun Huang, Baofeng Zhou, Liqing Zhu, Xianhui Kang, Wujun Geng
Identification of tumor antigens and immune subtypes of cholangiocarcinoma for mRNA vaccine development
Xing Huang, Tianyu Tang, Gang Zhang, Tingbo Liang
CircNEIL3 regulatory loop promotes pancreatic ductal adenocarcinoma progression via miRNA sponging and A-to-I RNA-editing
Peng Shen, Taoyue Yang, Qun Chen, Hao Yuan, Pengfei Wu, Baobao Cai, Lingdong Meng, Xumin Huang, Jiaye Liu, Yihan Zhang, Weikang Hu, Yi Miao, Zipeng Lu, Kuirong Jiang
Clinical and immunological effects of mRNA vaccines in malignant diseases
Annkristin Heine, Stefan Juranek, Peter Brossart
LMTK3 inhibition affects microtubule stability
Chiara Cilibrasi, Angeliki Ditsiou, Athanasios Papakyriakou, George Mavridis, Murat Eravci, Justin Stebbing, Teresa Gagliano, Georgios Giamas
RNA-based therapies: A cog in the wheel of lung cancer defense
Parvez Khan, Jawed Akhtar Siddiqui, Imayavaramban Lakshmanan, Apar Kishor Ganti, Ravi Salgia, Maneesh Jain, Surinder Kumar Batra, Mohd Wasim Nasser
Delivery of cancer therapies by synthetic and bio-inspired nanovectors
Tina Briolay, Tacien Petithomme, Morgane Fouet, Nelly Nguyen-Pham, Christophe Blanquart, Nicolas Boisgerault
Correction to: LncRNA PVT1 up-regulation is a poor prognosticator and serves as a therapeutic target in esophageal adenocarcinoma
Yan Xu, Yuan Li, Jiankang Jin, Guangchun Han, Chengcao Sun, Melissa Pool Pizzi, Longfei Huo, Ailing Scott, Ying Wang, Lang Ma, Jeffrey H. Lee, Manoop S. Bhutani, Brian Weston, Christopher Vellano, Liuqing Yang, Chunru Lin, Youngsoo Kim, A. Robert MacLeod, Linghua Wang, Zhenning Wang, Shumei Song, Jaffer A. Ajani
Plasma-derived exosomal miR-15a-5p as a promising diagnostic biomarker for early detection of endometrial carcinoma
Lanyun Zhou, Wei Wang, Fenfen Wang, Siqi Yang, Jiaqi Hu, Bingjian Lu, Zimin Pan, Yu Ma, Mengyue Zheng, Liyuan Zhou, Shufeng Lei, Penghong Song, Pengyuan Liu, Weiguo Lu, Yan Lu
Circulating exosomal mRNA profiling identifies novel signatures for the detection of prostate cancer
Jin Ji, Rui Chen, Lin Zhao, Yalong Xu, Zhi Cao, Huan Xu, Xi Chen, Xiaolei Shi, Yasheng Zhu, Ji Lyu, Junfeng Jiang, Yue Wang, Tie Zhou, Jingyi He, Xuedong Wei, Jason Boyang Wu, Bo Yang, Fubo Wang
Platelets, immune cells and the coagulation cascade; friend or foe of the circulating tumour cell?
Mark P. Ward, Laura E. Kane, Lucy A. Norris, Bashir M. Mohamed, Tanya Kelly, Mark Bates, Andres Clarke, Nathan Brady, Cara M. Martin, Robert D. Brooks, Doug A. Brooks, Stavros Selemidis, Sean Hanniffy, Eric P. Dixon, Sharon A. O’Toole, John J. O’Leary
Correction to: CircLONP2 enhances colorectal carcinoma invasion and metastasis through modulating the maturation and exosomal dissemination of microRNA-17
Kai Han, Feng-Wei Wang, Chen-Hui Cao, Han Ling, Jie-Wei Chen, Ri-Xin Chen, Zi-Hao Feng, Jie Luo, Xiao-Han Jin, Jin-Ling Duan, Shu-Man Li, Ning-Fang Ma, Jing-Ping Yun, Xin-Yuan Guan, Zhi-Zhong Pan, Ping Lan, Rui-Hua Xu, Dan Xie
The m6A RNA methylation regulates oncogenic signaling pathways driving cell malignant transformation and carcinogenesis
Mohammad Burhan Uddin, Zhishan Wang, Chengfeng Yang
Targeting CXCR2 inhibits the progression of lung cancer and promotes therapeutic effect of cisplatin
Yuan Cheng, Fei Mo, Qingfang Li, Xuejiao Han, Houhui Shi, Siyuan Chen, Yuquan Wei, Xiawei Wei
An integrative functional genomics approach reveals EGLN1 as a novel therapeutic target in KRAS mutated lung adenocarcinoma
Francesca Reggiani, Elisabetta Sauta, Federica Torricelli, Eleonora Zanetti, Elena Tagliavini, Giacomo Santandrea, Giulia Gobbi, Giovanna Damia, Riccardo Bellazzi, Davide Ambrosetti, Alessia Ciarrocchi, Valentina Sancisi
Correction to: LncRNA PTAR promotes EMT and invasionmetastasis in serous ovarian cancer by competitively binding miR-101-3p to regulate ZEB1 expression
Haihai Liang, Tong Yu, Yue Han, Hua Jiang, Chengyu Wang, Tianyi You, Xiaoguang Zhao, Huitong Shan, Rui Yang, Lida Yang, Hongli Shan, Yunyan Gu
Correction to: LMTK3 inhibition affects microtubule Stability
Chiara Cilibrasi, Angeliki Ditsiou, Athanasios Papakyriakou, George Mavridis, Murat Eravci, Justin Stebbing, Teresa Gagliano, Georgios Giamas
A novel protein encoded by circMAPK1 inhibits progression of gastric cancer by suppressing activation of MAPK signaling
Tianlu Jiang, Yiwen Xia, Jialun Lv, Bowen Li, Ying Li, Sen Wang, Zhe Xuan, Li Xie, Shengkui Qiu, Zhongyuan He, Linjun Wang, Zekuan Xu
Comprehensive analyses of m6A regulators and interactive coding and non-coding RNAs across 32 cancer types
Sipeng Shen, Ruyang Zhang, Yue Jiang, Yi Li, Lijuan Lin, Zhonghua Liu, Yang Zhao, Hongbing Shen, Zhibin Hu, Yongyue Wei, Feng Chen
CircPTPRA blocks the recognition of RNA N6-methyladenosine through interacting with IGF2BP1 to suppress bladder cancer progression
Fei Xie, Chao Huang, Feng Liu, Hui Zhang, Xingyuan Xiao, Jiayin Sun, Xiaoping Zhang, Guosong Jiang
mRNA therapeutics in cancer immunotherapy
Jan D. Beck, Daniel Reidenbach, Nadja Salomon, Ugur Sahin, Özlem Türeci, Mathias Vormehr, Lena M. Kranz
CircLIFR synergizes with MSH2 to attenuate chemoresistance via MutSα/ATM-p73 axis in bladder cancer
Hui Zhang, Xingyuan Xiao, Wenjie Wei, Chao Huang, Miao Wang, Liang Wang, Yuanqiao He, Jiayin Sun, Yangkai Jiang, Guosong Jiang, Xiaoping Zhang
The role and application of small extracellular vesicles in gastric cancer
Hao Wu, Mengdi Fu, Jin Liu, Wei Chong, Zhen Fang, Fengying Du, Yang Liu, Liang Shang, Leping Li
Nonsense-mediated RNA decay and its bipolar function in cancer
Gonçalo Nogueira, Rafael Fernandes, Juan F. García-Moreno, Luísa Romão
Cancer-associated fibroblast-derived gene signatures determine prognosis in colon cancer patients
Mercedes Herrera, Alberto Berral-González, Igor López-Cade, Cristina Galindo-Pumariño, Santiago Bueno-Fortes, Manuel Martín-Merino, Alfredo Carrato, Alberto Ocaña, Carolina De La Pinta, Ana López-Alfonso, Cristina Peña, Vanesa García-Barberán, Javier De Las Rivas
Pals1 prevents Rac1-dependent colorectal cancer cell metastasis by inhibiting Arf6
Simona Mareike Lüttgenau, Christin Emming, Thomas Wagner, Julia Harms, Justine Guske, Katrin Weber, Ute Neugebauer, Rita Schröter, Olga Panichkina, Zoltán Pethő, Florian Weber, Albrecht Schwab, Anja Kathrin Wege, Pavel Nedvetsky, Michael P. Krahn
CircMEMO1 modulates the promoter methylation and expression of TCF21 to regulate hepatocellular carcinoma progression and sorafenib treatment sensitivity
Zhao-Ru Dong, Ai-Wu Ke, Tao Li, Jia-Bing Cai, Ya-fei Yang, Wei Zhou, Guo-Ming Shi, Jia Fan
The intersection of COVID-19 and cancer: signaling pathways and treatment implications
Zhi Zong, Yujun Wei, Jiang Ren, Long Zhang, Fangfang Zhou
KDM6A-ARHGDIB axis blocks metastasis of bladder cancer by inhibiting Rac1
Lei Liu, Jianfeng Cui, Yajing Zhao, Xiaochen Liu, Lipeng Chen, Yangyang Xia, Yong Wang, Shouzhen Chen, Shuna Sun, Benkang Shi, Yongxin Zou
A new KSRP-binding compound suppresses distant metastasis of colorectal cancer by targeting the oncogenic KITENIN complex
Jeong A Bae, Woo Kyun Bae, Sung Jin Kim, Yoo-Seung Ko, Keon Young Kim, So-Yeon Park, Young Hyun Yu, Eun Ae Kim, Ik Joo Chung, Hangun Kim, Hyung-Ho Ha, Kyung Keun Kim
EYA2 suppresses the progression of hepatocellular carcinoma via SOCS3-mediated blockade of JAK/STAT signaling
Ze-Kun Liu, Can Li, Ren-Yu Zhang, Ding Wei, Yu-Kui Shang, Yu-Le Yong, Ling-Min Kong, Nai-Shan Zheng, Ke Liu, Meng Lu, Man Liu, Cai-Xia Hu, Xiao-Zhen Yang, Zhi-Nan Chen, Huijie Bian
GM-CSF mediates immune evasion via upregulation of PD-L1 expression in extranodal natural killer/T cell lymphoma
Qi-xiang Rong, Fang Wang, Zhi-xing Guo, Yi Hu, Sai-nan An, Min Luo, Hong Zhang, Shao-cong Wu, Hui-qiang Huang, Li-wu Fu
The circular RNA circSPARC enhances the migration and proliferation of colorectal cancer by regulating the JAK/STAT pathway
Jiaqi Wang, Yi Zhang, Hu Song, Hang Yin, Tao Jiang, Yixin Xu, Lianyu Liu, Hongyu Wang, Hong Gao, Renhao Wang, Jun Song
Liquid biopsy for therapy monitoring in early-stage non-small cell lung cancer
Misako Nagasaka, Mohammed Hafiz Uddin, Mohammed Najeeb Al-Hallak, Sarah Rahman, Suresh Balasubramanian, Ammar Sukari, Asfar S. Azmi
The roles of tumor-derived exosomes in altered differentiation, maturation and function of dendritic cells
Reza Hosseini, Leila Asef-Kabiri, Hassan Yousefi, Hamzeh Sarvnaz, Majid Salehi, Mohammad Esmaeil Akbari, Nahid Eskandari
CHEK1 and circCHEK1_246aa evoke chromosomal instability and induce bone lesion formation in multiple myeloma
Chunyan Gu, Wang Wang, Xiaozhu Tang, Tingting Xu, Yanxin Zhang, Mengjie Guo, Rongfang Wei, Yajun Wang, Artur Jurczyszyn, Siegfried Janz, Meral Beksac, Fenghuang Zhan, Anja Seckinger, Dirk Hose, Jingxuan Pan, Ye Yang
Novel induction of CD40 expression by tumor cells with RAS/RAF/PI3K pathway inhibition augments response to checkpoint blockade
Chi Yan, Nabil Saleh, Jinming Yang, Caroline A. Nebhan, Anna E. Vilgelm, E. Premkumar Reddy, Joseph T. Roland, Douglas B. Johnson, Sheau-Chiann Chen, Rebecca L. Shattuck-Brandt, Gregory D. Ayers, Ann Richmond
Germinal epimutation of Fragile Histidine Triad (FHIT) gene is associated with progression to acute and chronic adult T-cell leukemia diseases
Marcia Bellon, Izabela Bialuk, Veronica Galli, Xue-Tao Bai, Lourdes Farre, Achilea Bittencourt, Ambroise Marçais, Michael N. Petrus, Lee Ratner, Thomas A. Waldmann, Vahid Asnafi, Antoine Gessain, Masao Matsuoka, Genoveffa Franchini, Olivier Hermine, Toshiki Watanabe, Christophe Nicot
Correction to: Activation of LncRNA TINCR by H3K27 acetylation promotes Trastuzumab resistance and epithelial-mesenchymal transition by targeting MicroRNA-125b in breast Cancer
Huaying Dong, Jianguo Hu, Kejian Zou, Mulin Ye, Yuanwen Chen, Chengyi Wu, Xin Chen, Mingli Han
Identification of lymphocyte cell-specific protein-tyrosine kinase (LCK) as a driver for invasion and migration of oral cancer by tumor heterogeneity exploitation
Jonas Weiße, Julia Rosemann, Lisa Müller, Matthias Kappler, Alexander W. Eckert, Markus Glaß, Danny Misiak, Stefan Hüttelmaier, Wolfgang G. Ballhausen, Mechthild Hatzfeld, Monika Haemmerle, Tony Gutschner
Retraction Note to: Effects of HDM2 antagonism on sunitinib resistance, p53 activation, SDF-1 induction, and tumor infiltration by CD11b+/Gr-1+ myeloid derived suppressor cells
David J. Panka, Qingjun Liu, Andrew K. Geissler, James W. Mier
Histone citrullination: a new target for tumors
Dongwei Zhu, Yue Zhang, Shengjun Wang
The circACTN4 interacts with FUBP1 to promote tumorigenesis and progression of breast cancer by regulating the expression of proto-oncogene MYC
Xiaosong Wang, Lei Xing, Rui Yang, Hang Chen, Min Wang, Rong Jiang, Luyu Zhang, Junxia Chen
Retraction Note to: Differential modulatory effects of GSK-3b and HDM2 on sorafenib-induced AIF nuclear translocation (programmed necrosis) in melanoma
Qingjun Liu, James W. Mier, David J. Panka
Circ3823 contributes to growth, metastasis and angiogenesis of colorectal cancer: involvement of miR-30c-5p/TCF7 axis
Yaxin Guo, Yuying Guo, Chen Chen, Dandan Fan, Xiaoke Wu, Luyang Zhao, Bo Shao, Zhenqiang Sun, Zhenyu Ji
Long non-coding RNA ANRIL promotes homologous recombination-mediated DNA repair by maintaining ATR protein stability to enhance cancer resistance
Lei Liu, Yuanyuan Chen, Yijuan Huang, Kun Cao, Tingting Liu, Hui Shen, Jianguo Cui, Bailong Li, Jianming Cai, Fu Gao, Yanyong Yang
A novel class of tsRNA signatures as biomarkers for diagnosis and prognosis of pancreatic cancer
Fangfang Jin, Liuqing Yang, Weixiang Wang, Na Yuan, Shoubin Zhan, Ping Yang, Xi Chen, Tonghui Ma, Yanbo Wang
A urine extracellular vesicle circRNA classifier for detection of high-grade prostate cancer in patients with prostate-specific antigen 2–10 ng/mL at initial biopsy
Ya-Di He, Wen Tao, Tao He, Bang-Yu Wang, Xiu-Mei Tang, Liang-Ming Zhang, Zhen-Quan Wu, Wei-Ming Deng, Ling-Xiao Zhang, Chun-Kui Shao, Jing Zhou, Li-Min Rong, Xin Gao, Liao-Yuan Li
Translational evidence for RRM2 as a prognostic biomarker and therapeutic target in Ewing sarcoma
Shunya Ohmura, Aruna Marchetto, Martin F. Orth, Jing Li, Susanne Jabar, Andreas Ranft, Endrit Vinca, Katharina Ceranski, Martha J. Carreño-Gonzalez, Laura Romero-Pérez, Fabienne S. Wehweck, Julian Musa, Felix Bestvater, Maximilian M. L. Knott, Tilman L. B. Hölting, Wolfgang Hartmann, Uta Dirksen, Thomas Kirchner, Florencia Cidre-Aranaz, Thomas G. P. Grünewald
Circular RNA circIKBKB promotes breast cancer bone metastasis through sustaining NF-κB/bone remodeling factors signaling
Yingru Xu, Shuxia Zhang, Xinyi Liao, Man Li, Suwen Chen, Xincheng Li, Xingui Wu, Meisongzhu Yang, Miaoling Tang, Yameng Hu, Ziwen Li, Ruyuan Yu, Mudan Huang, Libing Song, Jun Li
Exosome-derived noncoding RNAs in gastric cancer: functions and clinical applications
Xiao-Huan Tang, Ting Guo, Xiang-Yu Gao, Xiao-Long Wu, Xiao-Fang Xing, Jia-Fu Ji, Zi-Yu Li
SPOP-mediated ubiquitination and degradation of PDK1 suppresses AKT kinase activity and oncogenic functions
Qiwei Jiang, Nana Zheng, Lang Bu, Xiaomei Zhang, Xiaoling Zhang, Yuanzhong Wu, Yaqing Su, Lei Wang, Xiaomin Zhang, Shancheng Ren, Xiangpeng Dai, Depei Wu, Wei Xie, Wenyi Wei, Yasheng Zhu, Jianping Guo
CircDIDO1 inhibits gastric cancer progression by encoding a novel DIDO1-529aa protein and regulating PRDX2 protein stability
Yu Zhang, Jiajia Jiang, Jiayin Zhang, Han Shen, Maoye Wang, Zhen Guo, Xueyan Zang, Hui Shi, Jiayan Gao, Hui Cai, Xinjian Fang, Hui Qian, Wenrong Xu, Xu Zhang
Correction to: Discovery of a novel third-generation EGFR inhibitor and identification of a potential combination strategy to overcome resistance
Tao Zhang, Rong Qu, Shingpan Chan, Mengzhen Lai, Linjiang Tong, Fang Feng, Hongyu Chen, Tingting Song, Peiran Song, Gang Bai, Yingqiang Liu, Yanan Wang, Yan Li, Yi Su, Yanyan Shen, Yiming Sun, Yi Chen, Meiyu Geng, Ke Ding, Jian Ding, Hua Xie
A novel NF-κB regulator encoded by circPLCE1 inhibits colorectal carcinoma progression by promoting RPS3 ubiquitin-dependent degradation
Zhen-xing Liang, Hua-shan Liu, Li Xiong, Xin Yang, Feng-wei Wang, Zi-wei Zeng, Xiao-wen He, Xian-rui Wu, Ping Lan
Using single-cell sequencing technology to detect circulating tumor cells in solid tumors
Jiasheng Xu, Kaili Liao, Xi Yang, Chengfeng Wu, Wei Wu
N6-methyladenosine-modified circIGF2BP3 inhibits CD8+ T-cell responses to facilitate tumor immune evasion by promoting the deubiquitination of PD-L1 in non-small cell lung cancer
Zhenchuan Liu, Tingting Wang, Yunlang She, Kaiqing Wu, Shaorui Gu, Lei Li, Chenglai Dong, Chang Chen, Yongxin Zhou
Circular RNA CircEYA3 induces energy production to promote pancreatic ductal adenocarcinoma progression through the miR-1294/c-Myc axis
Zeyin Rong, Si Shi, Zhen Tan, Jin Xu, Qingcai Meng, Jie Hua, Jiang Liu, Bo Zhang, Wei Wang, Xianjun Yu, Chen Liang
RIPK3 activation induces TRIM28 derepression in cancer cells and enhances the anti-tumor microenvironment
Han-Hee Park, Hwa-Ryeon Kim, Sang-Yeong Park, Sung-Min Hwang, Sun Mi Hong, Sangwook Park, Ho Chul Kang, Michael J. Morgan, Jong-Ho Cha, Dakeun Lee, Jae-Seok Roe, You-Sun Kim
DDX56 modulates post-transcriptional Wnt signaling through miRNAs and is associated with early recurrence in squamous cell lung carcinoma
Qingqing Wu, Xiaoyang Luo, Mikkel G. Terp, Qingrun Li, Yuan Li, Lei Shen, Ying Chen, Kirstine Jacobsen, Trever G. Bivona, Haiquan Chen, Rong Zeng, Henrik J. Ditzel
Retraction Note to: Loss of PDEF, a prostate-derived Ets factor is associated with aggressive phenotype of prostate cancer: Regulation of MMP 9 by PDEF
Thomas R. Johnson, Sweaty Koul, Binod Kumar, Lakshmipathi Khandrika, Sarah Venezia, Paul D. Maroni, Randall B. Meacham, Hari K. Koul
Correction to: LncRNA-HGBC stabilized by HuR promotes gallbladder cancer progression by regulating miR-502-3p/SET/AKT axis
Yun-ping Hu, Yun-peng Jin, Xiang-song Wu, Yang Yang, Yong-sheng Li, Huai-feng Li, Shan-shan Xiang, Xiao-ling Song, Lin Jiang, Yi-jian Zhang, Wen Huang, Shi-li Chen, Fa-tao Liu, Chen Chen, Qin Zhu, Hong-zhuan Chen, Rong Shao, Ying-bin Liu
Uncovering cancer vulnerabilities by machine learning prediction of synthetic lethality
Salvatore Benfatto, Özdemirhan Serçin, Francesca R. Dejure, Amir Abdollahi, Frank T. Zenke, Balca R. Mardin
Circular RNA circRNF13 inhibits proliferation and metastasis of nasopharyngeal carcinoma via SUMO2
Yongzhen Mo, Yumin Wang, Shuai Zhang, Fang Xiong, Qijia Yan, Xianjie Jiang, Xiangying Deng, Yian Wang, Chunmei Fan, Le Tang, Shanshan Zhang, Zhaojian Gong, Fuyan Wang, Qianjin Liao, Can Guo, Yong Li, Xiaoling Li, Guiyuan Li, Zhaoyang Zeng, Wei Xiong
Small extrachromosomal circular DNA (eccDNA): major functions in evolution and cancer
Xiaoxuan Ling, Yali Han, Jinxue Meng, Bohuan Zhong, Jialong Chen, He Zhang, Jiheng Qin, Jing Pang, Linhua Liu
CircMYH9 drives colorectal cancer growth by regulating serine metabolism and redox homeostasis in a p53-dependent manner
Xin Liu, Yunze Liu, Zhao Liu, Changwei Lin, Fanchao Meng, Lei Xu, Xiuzhong Zhang, Chong Zhang, Penbo Zhang, Shuai Gong, Nai Wu, Zeqiang Ren, Jun Song, Yi Zhang
An ADAR1-dependent RNA editing event in the cyclin-dependent kinase CDK13 promotes thyroid cancer hallmarks
Julia Ramírez-Moya, Christos Miliotis, Allison R. Baker, Richard I. Gregory, Frank J. Slack, Pilar Santisteban
The role of lncRNAs and circRNAs in the PD-1/PD-L1 pathway in cancer immunotherapy
Wenxiao Jiang, Shuya Pan, Xin Chen, Zhi-wei Wang, Xueqiong Zhu
Tumor-associated exosomes promote lung cancer metastasis through multiple mechanisms
Chunyang Jiang, Na Zhang, Xiaoli Hu, Hongyan Wang
MG53 suppresses tumor progression and stress granule formation by modulating G3BP2 activity in non-small cell lung cancer
Haichang Li, Pei-Hui Lin, Pranav Gupta, Xiangguang Li, Serena Li Zhao, Xinyu Zhou, Zhongguang Li, Shengcai Wei, Li Xu, Renzhi Han, Jing Lu, Tao Tan, Dong-Hua Yang, Zhe-Sheng Chen, Timothy M. Pawlik, Robert E. Merritt, Jianjie Ma
Circular RNAs’ cap-independent translation protein and its roles in carcinomas
Lian He, Changfeng Man, Shouyan Xiang, Lin Yao, Xiaoyan Wang, Yu Fan
Correction to: The lncRNA UCA1 promotes proliferation, migration, immune escape and inhibits apoptosis in gastric cancer by sponging anti-tumor miRNAs
Chao-Jie Wang, Chun-Chao Zhu, Jia Xu, Ming Wang, Wen-Yi Zhao, Qiang Liu, Gang Zhao, Zi-Zhen Zhang
Crosstalk between N6-methyladenosine modification and circular RNAs: current understanding and future directions
Xin Wang, Rui Ma, Xilin Zhang, Lian Cui, Yangfeng Ding, Weimin Shi, Chunyuan Guo, Yuling Shi
The landscape of m6A regulators in small cell lung cancer: molecular characteristics, immuno-oncology features, and clinical relevance
Chaoqi Zhang, Zhihui Zhang, Zhen Zhang, Yuejun Luo, Peng Wu, Guochao Zhang, Liyan Xue, Qingpeng Zeng, Lide Wang, Zhaoyang Yang, Hua Zeng, Bo Zheng, Fengwei Tan, Qi Xue, Shugeng Gao, Nan Sun, Jie He
p113 isoform encoded by CUX1 circular RNA drives tumor progression via facilitating ZRF1/BRD4 transactivation
Feng Yang, Anpei Hu, Yanhua Guo, Jianqun Wang, Dan Li, Xiaojing Wang, Shikai Jin, Boling Yuan, Shuang Cai, Yi Zhou, Qilan Li, Guo Chen, Haiyang Gao, Liduan Zheng, Qiangsong Tong
Single-cell RNA sequencing reveals markers of disease progression in primary cutaneous T-cell lymphoma
Katharina Rindler, Constanze Jonak, Natalia Alkon, Felix M. Thaler, Harald Kurz, Lisa E. Shaw, Georg Stingl, Wolfgang Weninger, Florian Halbritter, Wolfgang M. Bauer, Matthias Farlik, Patrick M. Brunner
Patient derived organoids in prostate cancer: improving therapeutic efficacy in precision medicine
Sahithi Pamarthy, Hatem E. Sabaawy
Application of the CRISPR/Cas9-based gene editing technique in basic research, diagnosis, and therapy of cancer
Huimin Zhang, Chunhong Qin, Changming An, Xiwang Zheng, Shuxin Wen, Wenjie Chen, Xianfang Liu, Zhenghua Lv, Pingchang Yang, Wei Xu, Wei Gao, Yongyan Wu
Tetraspanin8 expression predicts an increased metastatic risk and is associated with cancer-related death in human cutaneous melanoma
Odile Berthier-Vergnes, Laetitia Barbollat-Boutrand, Roxane M. Pommier, Arnaud de la Fouchardière, Patrick Combemale, Maxime Grimont, Noémie Lopez-Ramirez, Julie Caramel, Stéphane Dalle, Jean-Luc Perrot, Caroline Gaudy-Marqueste, Nicolas Macagno, Sandrine Mansard, Fanny Bouquet, Ingrid Masse
Oncogenic KRAS blockade therapy: renewed enthusiasm and persistent challenges
Daolin Tang, Guido Kroemer, Rui Kang
Peritoneal metastasis of colorectal cancer (pmCRC): identification of predictive molecular signatures by a novel preclinical platform of matching pmCRC PDX/PD3D models
Mathias Dahlmann, Guido Gambara, Bernadette Brzezicha, Oliver Popp, Eva Pachmayr, Lena Wedeken, Alina Pflaume, Margarita Mokritzkij, Safak Gül-Klein, Andreas Brandl, Caroline Schweiger-Eisbacher, Philipp Mertins, Jens Hoffmann, Ulrich Keilholz, Wolfgang Walther, Christian Regenbrecht, Beate Rau, Ulrike Stein
Profiling of DNA damage and repair pathways in small cell lung cancer reveals a suppressive role in the immune landscape
Renjing Jin, Bin Liu, Mengjun Yu, Liwei Song, Meng Gu, Ziyu Wang, Xiaobo Li, Xu Zhang, Jinghui Wang, Teng Ma
Crosstalk between cancer-associated fibroblasts and immune cells in the tumor microenvironment: new findings and future perspectives
Xiaoqi Mao, Jin Xu, Wei Wang, Chen Liang, Jie Hua, Jiang Liu, Bo Zhang, Qingcai Meng, Xianjun Yu, Si Shi
Circular RNA circIPO11 drives self-renewal of liver cancer initiating cells via Hedgehog signaling
Yang Gu, Yanying Wang, Luyun He, Jiahang Zhang, Xiaoxiao Zhu, Nian Liu, Jianyi Wang, Tiankun Lu, Lei He, Yong Tian, Zusen Fan
AMPK promotes antitumor immunity by downregulating PD-1 in regulatory T cells via the HMGCR/p38 signaling pathway
Ram Hari Pokhrel, Suman Acharya, Jae-Hee Ahn, Ye Gu, Mahesh Pandit, Jong-Oh Kim, Yun-Yong Park, Ben Kang, Hyun-Jeong Ko, Jae-Hoon Chang
DDX3X loss is an adverse prognostic marker in diffuse large B-cell lymphoma and is associated with chemoresistance in aggressive non-Hodgkin lymphoma subtypes
Atish Kizhakeyil, Nurmahirah Binte Mohammed Zaini, Zhi Sheng Poh, Brandon Han Siang Wong, Xinpeng Loh, Aik Seng Ng, Zun Siong Low, Praseetha Prasannan, Chun Gong, Michelle Guet Khim Tan, Chandramouli Nagarajan, Dachuan Huang, Pang Wan Lu, Jing Quan Lim, Sharon Barrans, Choon Kiat Ong, Soon Thye Lim, Wee Joo Chng, George Follows, Daniel J. Hodson, Ming Qing Du, Yeow Tee Goh, Suat Hoon Tan, Nicholas Francis Grigoropoulos, Navin Kumar Verma
Correction to: Transcriptional inhibition by CDK7/9 inhibitor SNS-032 abrogates oncogene addiction and reduces liver metastasis in uveal melanoma
Jing Zhang, Shenglan Liu, Qianyun Ye, Jingxuan Pan
Experimental and computational modeling for signature and biomarker discovery of renal cell carcinoma progression
Lindsay S. Cooley, Justine Rudewicz, Wilfried Souleyreau, Andrea Emanuelli, Arturo Alvarez-Arenas, Kim Clarke, Francesco Falciani, Maeva Dufies, Diether Lambrechts, Elodie Modave, Domitille Chalopin-Fillot, Raphael Pineau, Damien Ambrosetti, Jean-Christophe Bernhard, Alain Ravaud, Sylvie Négrier, Jean-Marc Ferrero, Gilles Pagès, Sebastien Benzekry, Macha Nikolski, Andreas Bikfalvi
Correction to: Ponatinib efficiently kills imatinib-resistant chronic eosinophilic leukemia cells harboring gatekeeper mutant T674I FIP1L1-PDGFRα: roles of Mcl-1 and β-catenin
Yanli Jin, Ke Ding, Honglin Li, Mengzhu Xue, Xiaoke Shi, Chengyan Wang, Jingxuan Pan
CircCD44 plays oncogenic roles in triple-negative breast cancer by modulating the miR-502–5p/KRAS and IGF2BP2/Myc axes
Jie Li, Xinya Gao, Zhanqiang Zhang, Yuanhui Lai, Xunxun Lin, Bo Lin, Maoguang Ma, Xiaoli Liang, Xixi Li, Weiming Lv, Ying Lin, Nu Zhang
CircRNF220, not its linear cognate gene RNF220, regulates cell growth and is associated with relapse in pediatric acute myeloid leukemia
Xiaodan Liu, Xiaoping Liu, Mansi Cai, Ailing Luo, Yingyi He, Sha Liu, Xiaohong Zhang, Xu Yang, Ling Xu, Hua Jiang
Crosstalk between autophagy inhibitors and endosome-related secretory pathways: a challenge for autophagy-based treatment of solid cancers
Martina Raudenska, Jan Balvan, Michal Masarik
The tumor suppressor activity of DLC1 requires the interaction of its START domain with Phosphatidylserine, PLCD1, and Caveolin-1
Beatriz Sanchez-Solana, Dunrui Wang, Xiaolan Qian, Parthibane Velayoudame, Dhirendra K. Simanshu, Jairaj K. Acharya, Douglas R. Lowy
ciRS-7 is a prognostic biomarker and potential gene therapy target for renal cell carcinoma
Weipu Mao, Keyi Wang, Bin Xu, Hui Zhang, Si Sun, Qiang Hu, Lei Zhang, Chunhui Liu, Shuqiu Chen, Jianping Wu, Ming Chen, Wei Li, Bo Peng
Role of oncogenic KRAS in the prognosis, diagnosis and treatment of colorectal cancer
Gongmin Zhu, Lijiao Pei, Hongwei Xia, Qiulin Tang, Feng Bi
Cancer cell-derived exosomal circUSP7 induces CD8+ T cell dysfunction and anti-PD1 resistance by regulating the miR-934/SHP2 axis in NSCLC
Shi-Wei Chen, Shu-Qiang Zhu, Xu Pei, Bai-Quan Qiu, Dian Xiong, Xiang Long, Kun Lin, Feng Lu, Jian-Jun Xu, Yong-Bing Wu
The role of distinct BRD4 isoforms and their contribution to high-grade serous ovarian carcinoma pathogenesis
Ana Luiza Drumond-Bock, Magdalena Bieniasz
Hiding in the dark: pan-cancer characterization of expression and clinical relevance of CD40 to immune checkpoint blockade therapy
Chi Yan, Ann Richmond
STK3 promotes gastric carcinogenesis by activating Ras-MAPK mediated cell cycle progression and serves as an independent prognostic biomarker
Bonan Chen, Wai Nok Chan, Chun Wai Mui, Xiaoli Liu, Jinglin Zhang, Yifei Wang, Alvin H. K. Cheung, Aden K. Y. Chan, Ronald C. K. Chan, Kam Tong Leung, Yujuan Dong, Yi Pan, Huixing Ke, Li Liang, Zhaocai Zhou, Chi Chun Wong, William K. K. Wu, Alfred S. L. Cheng, Jun Yu, Kwok Wai Lo, Ka Fai To, Wei Kang
DREAM: a database of experimentally supported protein-coding RNAs and drug associations in human cancer
Shupeng Li, Lulu Li, Xiangqi Meng, Penggang Sun, Yi Liu, Yuntang Song, Sijia Zhang, Chuanlu Jiang, Jinquan Cai, Zheng Zhao
Circular RNAs in acute myeloid leukemia
Vijendra Singh, Mohammed Hafiz Uddin, Jeffrey A. Zonder, Asfar S. Azmi, Suresh Kumar Balasubramanian
Remodeling of the tumor microenvironment via disrupting Blimp1+ effector Treg activity augments response to anti-PD-1 blockade
Michael L. Dixon, Lin Luo, Sadashib Ghosh, Jeffrey M. Grimes, Jonathan D. Leavenworth, Jianmei W. Leavenworth
Liquid biopsy identifies actionable dynamic predictors of resistance to Trastuzumab Emtansine (T-DM1) in advanced HER2-positive breast cancer
Matteo Allegretti, Alessandra Fabi, Elena Giordani, Cristiana Ercolani, Paolo Romania, Cecilia Nisticò, Simona Gasparro, Vittoria Barberi, Maria Ciolina, Edoardo Pescarmona, Diana Giannarelli, Gennaro Ciliberto, Francesco Cognetti, Patrizio Giacomini
Correction to: Antagonizing miR-455-3p inhibits chemoresistance and aggressiveness in esophageal squamous cell carcinoma
Aibin Liu, Jinrong Zhu, Geyan Wu, Lixue Cao, Zhanyao Tan, Shuxia Zhang, Lili Jiang, Jueheng Wu, Mengfeng Li, Libing Song, Jun Li
CircEAF2 counteracts Epstein-Barr virus-positive diffuse large B-cell lymphoma progression via miR-BART19-3p/APC/β-catenin axis
Chen-xing Zhao, Zi-xun Yan, Jing-jing Wen, Di Fu, Peng-peng Xu, Li Wang, Shu Cheng, Jian-da Hu, Wei-li Zhao
Cancer associated-fibroblast-derived exosomes in cancer progression
Chao Li, Adilson Fonseca Teixeira, Hong-Jian Zhu, Peter ten Dijke
Correction to: ciRS-7 is a prognostic biomarker and potential gene therapy target for renal cell carcinoma
Weipu Mao, Keyi Wang, Bin Xu, Hui Zhang, Si Sun, Qiang Hu, Lei Zhang, Chunhui Liu, Shuqiu Chen, Jianping Wu, Ming Chen, Wei Li, Bo Peng
LncRNA PKMYT1AR promotes cancer stem cell maintenance in non-small cell lung cancer via activating Wnt signaling pathway
Yaomei He, Xiulin Jiang, Lincan Duan, Qiuxia Xiong, Yixiao Yuan, Peishen Liu, Liping Jiang, Qiushuo Shen, Song Zhao, Cuiping Yang, Yongbin Chen
EasyCatch, a convenient, sensitive and specific CRISPR detection system for cancer gene mutations
Yin Liu, Yanling Chen, Lu Dang, Yixin Liu, Shisheng Huang, Sanyun Wu, Peixiang Ma, Hongqiang Jiang, Yi Li, Yunbao Pan, Yongchang Wei, Xiaodong Ma, Ming Liu, Quanjiang Ji, Tian Chi, Xingxu Huang, Xinjie Wang, Fuling Zhou
A novel protein AXIN1-295aa encoded by circAXIN1 activates the Wnt/β-catenin signaling pathway to promote gastric cancer progression
Yin Peng, Yidan Xu, Xiaojing Zhang, Shiqi Deng, Yuan Yuan, Xiaonuan Luo, Md Tofazzal Hossain, Xiaohui Zhu, Kaining Du, Fan Hu, Yang Chen, Shanshan Chang, Xianling Feng, Xinmin Fan, Hassan Ashktorab, Duane Smoot, Stephen J. Meltzer, Gangqiang Hou, Yanjie Wei, Song Li, Ying Qin, Zhe Jin
Tumor antigens and immune subtypes guided mRNA vaccine development for kidney renal clear cell carcinoma
Hang Xu, Xiaonan Zheng, Shiyu Zhang, Xianyanling Yi, Tianyi Zhang, Qiang Wei, Hong Li, Jianzhong Ai
Tumor-antigens and immune landscapes identification for prostate adenocarcinoma mRNA vaccine
Xiaonan Zheng, Hang Xu, Xianyanling Yi, Tianyi Zhang, Qiang Wei, Hong Li, Jianzhong Ai
CircDOCK1 promotes the tumorigenesis and cisplatin resistance of osteogenic sarcoma via the miR-339-3p/IGF1R axis
Shenglong Li, Fei Liu, Ke Zheng, Wei Wang, Enduo Qiu, Yi Pei, Shuang Wang, Jiaming Zhang, Xiaojing Zhang
Long non-coding RNA NORAD/miR-224-3p/MTDH axis contributes to CDDP resistance of esophageal squamous cell carcinoma by promoting nuclear accumulation of β-catenin
Yunlong Jia, Cong Tian, Hongyan Wang, Fan Yu, Wei Lv, Yuqing Duan, Zishuo Cheng, Xuexiao Wang, Yu Wang, Tianxu Liu, Jiali Wang, Lihua Liu
Crosstalk between autophagy and microbiota in cancer progression
Yu Wang, Jiang Du, Xuemei Wu, Ahmed Abdelrehem, Yu Ren, Chao Liu, Xuan Zhou, Sinan Wang
Personalized neoantigen vaccine prevents postoperative recurrence in hepatocellular carcinoma patients with vascular invasion
Zhixiong Cai, Xiaoping Su, Liman Qiu, Zhenli Li, Xiaolou Li, Xiuqing Dong, Fuqun Wei, Yang Zhou, Liuping Luo, Geng Chen, Hengkai Chen, Yingchao Wang, Yongyi Zeng, Xiaolong Liu
IRAK1-regulated IFN-γ signaling induces MDSC to facilitate immune evasion in FGFR1-driven hematological malignancies
Baohuan Cai, Yun Liu, Yating Chong, Hualei Zhang, Atsuko Matsunaga, Xuexiu Fang, Rafal Pacholczyk, Gang Zhou, John K. Cowell, Tianxiang Hu
The circular RNA circDLG1 promotes gastric cancer progression and anti-PD-1 resistance through the regulation of CXCL12 by sponging miR-141-3p
Dong-Liang Chen, Hui Sheng, Dong-Sheng Zhang, Ying Jin, Bai-Tian Zhao, Nuo Chen, Kang Song, Rui-Hua Xu
CircIL4R activates the PI3K/AKT signaling pathway via the miR-761/TRIM29/PHLPP1 axis and promotes proliferation and metastasis in colorectal cancer
Tao Jiang, Hongyu Wang, Lianyu Liu, Hu Song, Yi Zhang, Jiaqi Wang, Lei Liu, Teng Xu, Ruizhi Fan, Yixin Xu, Shuai Wang, Linsen Shi, Li Zheng, Renhao Wang, Jun Song
Characterization of novel CTNNB1 mutation in Craniopharyngioma by whole-genome sequencing
Juan He, Zhen Zeng, Yuelong Wang, Jiaojiao Deng, Xin Tang, Fujun Liu, Jianhan Huang, Hongxu Chen, Ruichao Liang, Xin Zan, Zhiyong Liu, Aiping Tong, Gang Guo, Jianguo Xu, Xiaofeng Zhu, Liangxue Zhou, Yong Peng
circCHST15 is a novel prognostic biomarker that promotes clear cell renal cell carcinoma cell proliferation and metastasis through the miR-125a-5p/EIF4EBP1 axis
Cheng-Peng Gui, Bing Liao, Cheng-Gong Luo, Yu-Hang Chen, Lei Tan, Yi-Ming Tang, Jia-Ying Li, Yi Hou, Hong-De Song, Hai-Shan Lin, Quan-Hui Xu, Gao-Sheng Yao, Hao-Hua Yao, Xi-Liu, Jun-Hang Luo, Jia-Zheng Cao, Jin-Huan Wei
m6A target microRNAs in serum for cancer detection
Bo Zhang, Zhenmei Chen, Baorui Tao, Chenhe Yi, Zhifei Lin, Yitong Li, Weiqing Shao, Jing Lin, Jinhong Chen
Epigenetic modulation of antitumor immunity for improved cancer immunotherapy
Enyong Dai, Zhi Zhu, Shudipto Wahed, Zhaoxia Qu, Walter J. Storkus, Zong Sheng Guo
Correction to: Pristimerin induces apoptosis in imatinib-resistant chronic myelogenous leukemia cells harboring T315I mutation by blocking NF-κB signaling and depleting Bcr-Abl
Zhongzheng Lu, Yanli Jin, Chun Chen, Juan Li, Qi Cao, Jingxuan Pan