Ausgabe 2/2024
Inhalt (55 Artikel)
Environmental enrichment reverses proulcerogenic action of social isolation on the gastric mucosa and positively influences pain sensitivity and work capacity
- Review
Ludmila P. Filaretova, Olga P. Komkova, Olga Yu. Morozova, Polina V. Punina, Natalia I. Yarushkina
The effects of cholesterol and statins on Parkinson’s neuropathology: a narrative review
- Review
Hayder M. Al-kuraishy, Esraa H. Fahad, Salah Al-Windy, Suzy A. El-Sherbeni, Walaa A. Negm, Gaber El-Saber Batiha
The effects of melatonin supplementation on neurobehavioral outcomes and clinical severity in rodent models of multiple sclerosis; a systematic review and meta-analysis
- Review
Hadis Razmaray, Ehsan Nasiri, Pouya Vakilipour, Soroush Morsali, Afshin Moradi, Asal Ebrahimian, Sahel Rashidi, Reza Mosaddeghi-Heris, Saeed Sadigh-Eteghad, Amirreza Naseri
Repurposing metformin to manage idiopathic or long COVID Tinnitus: self-report adopting a pathophysiological and pharmacological approach
- Open Access
- Review Article
Mina T. Kelleni
The effects of silymarin consumption on inflammation and oxidative stress in adults: a systematic review and meta-analysis
- Review
Hossein Bahari, Mostafa Shahraki Jazinaki, Mohammad Rashidmayvan, Shaghayegh Taheri, Mohammad Reza Amini, Mahsa Malekahmadi
Role of corticosteroids in the treatment of critically ill sepsis patients: a meta-analysis review
- Review
Yutong Song, Jing Hao, Yanhua Liu
Pterostilbene: a potential therapeutic agent for fibrotic diseases
- Review
Wenhong Wang, Ke Li, Dandan Bai, Jiabin Wu, Weihua Xiao
A systematic review of interleukin-31 inhibitors in the treatment of prurigo nodularis
- Review
Mohammad Ali Nilforoushzadeh, Nazila Heidari, Yekta Ghane, Amirhossein Heidari, Arman Hajikarim-Hamedani, SeyedAyin Hosseini, Fariba Jaffary, Minou Najar Nobari, Pegah Tavakolzadeh, Niloufar Najar Nobari
Does non-steroidal anti-inflammatory drugs-related preemptive analgesia modulate SOCS3/IL-6 pathway in oral surgery?
- Original Article
Assis Filipe Medeiros Albuquerque, José Jackson do Nascimento Costa, José Roberto Viana Silva, Paulo Goberlânio de Barros Silva, Filipe Nobre Chaves, Eduardo Frederico Eduardo Maferano, Edson Luiz Cetira Filho, Karuza Maria Alves Pereira, Sérgio Lima Santiago, Thyciana Rodrigues Ribeiro, Fábio Wildson Gurgel Costa
Observational analysis of the immunogenicity and safety of various types of spinal muscular atrophy vaccines
- Original Article
Guojuan Sun, Guangzhi Wang, Heng Zhong
Effect of use of NSAIDs or steroids during the acute phase of pain on the incidence of chronic pain: a systematic review and meta-analysis of randomised trials
- Open Access
- Original Article
Luyao Huo, Gang Liu, Bowen Deng, Lin Xu, Yanjun Mo, Shengyuan Jiang, Jingwei Tao, Huizhong Bai, Li Wang, Xiaoxiao Yang, Jizhou Yang, Xiaohong Mu
Quercetin attenuates Pseudomonas aeruginosa-induced acute lung inflammation by inhibiting PI3K/AKT/NF-κB signaling pathway
- Original Article
Xiaolei Jia, Mengdi Gu, Jiangqin Dai, Jue Wang, Yingying Zhang, Zheng Pang
D-limonene inhibits peritoneal adhesion formation in rats via anti-inflammatory, anti-angiogenic, and antioxidative effects
- Original Article
Ali Razazi, Ali Kakanezhadi, Abbas Raisi, Behnam Pedram, Omid Dezfoulian, Farshid Davoodi
Neuroprotective potential of Erigeron bonariensis ethanolic extract against ovariectomized/D-galactose-induced memory impairments in female rats in relation to its metabolite fingerprint as revealed using UPLC/MS
- Open Access
- Original Article
Weam W. Ibrahim, Rabab H. Sayed, Mohamed F. Abdelhameed, Enayat A. Omara, Mahmoud I. Nassar, Noha F. Abdelkader, Mohamed A. Farag, Abdelsamed I. Elshamy, Sherif M. Afifi
Rapamycin can alleviate the submandibular gland pathology of Sjögren's syndrome by limiting the activation of cGAS–STING signaling pathway
- Original Article
Wen Zhu, Yabei Wang, Yin Guan, Yun Lu, Yehui Li, Lixia sun, Yue Wang
Pseudolaric acid B exerts an antifungal effect and targets SIRT1 to ameliorate inflammation by regulating Nrf2/NF-κB pathways in fungal keratitis
- Original Article
Shuyi Liu, Tao Qin, Fengkai Zou, He Dong, Liang Yu, Hai Wang, Lijun Zhang
Unraveling the potential of vitamins C and D as adjuvants in depression treatment with escitalopram in an LPS animal model
- Open Access
- Original Article
Omar Gammoh, Rand T. Akasheh, Esam Qnais, Sara Al-Taber, Rabaa Y. Athamneh, Amin A. Hafiz, Abdelrahim Alqudah, Alaa A. A. Aljabali, Murtaza M. Tambuwala
Glabridin reduces neuroinflammation by modulating inflammatory signals in LPS-induced in vitro and in vivo models
- Original Article
Jiyu Weng, Ying Wang, Zekai Tan, Yanghe Yuan, Shiyuan Huang, Zexi Li, Yiming Li, Lanyue Zhang, Zhiyun Du
Flavipin from fungi as a potential inhibitor of rheumatoid arthritis signaling molecules
- Original Article
Emad A. Ahmed, Abdulaah M. Alzahrani, Salah A. Abdelsalam, Hairul-Islam M. Ibrahim
Ameliorative effects of Atriplex crassifolia (C.A.Mey) on pain and inflammation through modulation of inflammatory biomarkers and GC–MS-based metabolite profiling
- Original Article
Sarah Rehman, Saiqa Ishtiaq, Muhammad Khalil-Ur-Rehman, Sairah Hafeez Kamran
Anti-rheumatoid arthritis potential of Halodule pinifolia: development, characterization and in vivo evaluation of H. pinifolia-based oral suspension and lipid nano-emulsion
- Original Article
Samun Nessa, S. Lavanya, Rajesh K. Routray, Akash Chaurasiya, Onkar P. Kulkarni, A. Sajeli Begum
Anti-inflammatory and anti-arthritic potential of Coagulansin-A: in vitro and in vivo studies
- Original Article
Sadaf Naz, Muhammad Usama Mazhar, Umakant Yadav, Hamdy Abouzeid Ali, Fadi Khasawneh, Ihsan-ul-Haq, Muhammad Khalid Tipu, Lin Zhu
Intraarticular monomethyl fumarate as a perspective therapy for osteoarthritis by macrophage polarization
- Original Article
Douglas Menezes de Souza, Kauê Franco Malange, Catarine Massucato Nishijima, Bruno Henrique de Melo Lima, Vinicius Cooper Capetini, Alexandre L. R. de Oliveira, Gabriel Forato Anhê, Claudia Herrera Tambeli, Carlos Amilcar Parada
Association of statin use with osteoporosis risk: a drug-targeted Mendelian randomization study
- Original Article
Zhaozhou Ren, Long Zhou
Antinociceptive and anti-inflammatory activity of extracts and α-pyrones isolated from Cantinoa stricta
- Original Article
Felipe Lukacievicz Barbosa, Carlos Augusto Ehrenfried, Débora Rasec Radulski, Cristhian Santos Oliveira, Maria Élida Alves Stefanello, Aleksander Roberto Zampronio
Sulfasalazine promotes ferroptosis through AKT-ERK1/2 and P53-SLC7A11 in rheumatoid arthritis
- Open Access
- Original Article
Chenyu Zhao, Yunyuan Yu, Guangrong Yin, Chao Xu, Jiahao Wang, Liangliang Wang, Gongyin Zhao, Su Ni, Haoxing Zhang, Baojun Zhou, Yuji Wang
Neuroprotective effects of rutin against cuprizone-induced multiple sclerosis in mice
- Open Access
- Original Article
Mariam A. Nicola, Abdelraheim H. Attaai, Mahmoud H. Abdel-Raheem, Anber F. Mohammed, Yasmin F. Abu-Elhassan
Synergistic effects of mesenchymal stem cell-derived extracellular vesicles and dexamethasone on macrophage polarization under inflammatory conditions
- Original Article
Zahra Mirsanei, Fatemeh Jamshidi-Adegani, Saeid Vakilian, Fateme Ahangari, Sara Soufihasanabad, Khamis Al-Riyami, Sara Soudi, Sahar Ghaffari Khaligh, Sulaiman Al-Hashmi, Seyed Mahmoud Hashemi
Synthesis of novel nonsteroidal anti-inflammatory galloyl β-sitosterol-loaded lignin-capped Ag-based drug
- Original Article
Sana Malik, Batool Fatima, Dilshad Hussain, Muhammad Imran, Tahir Ali Chohan, Muhammad Saqib Khan, Saadat Majeed, Muhammad Najam-ul-Haq
Isolation, invitro, invivo anti-inflammatory, analgesic and antioxidant potential of Habenaria plantegania Lindl
- Original Article
Osama M. Alshehri, Madeeha Shabnam, Saeed Ahmed Asiri, Mater H. Mahnashi, Abdul Sadiq, Muhammad Saeed Jan
3-Acetyl coumarin alleviate neuroinflammatory responses and oxidative stress in aluminum chloride-induced Alzheimer’s disease rat model
- Original Article
Zakiah Zeb, Ali Sharif, Bushra Akhtar, Shahnaz
Sinomenine protects against atherosclerosis in apolipoprotein E-knockout mice by inhibiting of inflammatory pathway
- Original Article
Zhao Gao, Chao Yang, Guangwei Zeng, Ming Lin, Wei Li, Mengna Sun, Yantao Zhang, Beibei Fan, Yogesh Kumar, Kun Yan
Folic acid improved memory and learning function in a rat model of neuroinflammation induced by lipopolysaccharide
- Original Article
Zahra Kioumarsi Darbandi, Sabiheh Amirahmadi, Iran Goudarzi, Mahmoud Hosseini, Arezoo Rajabian
The effects of probiotic supplements on oxidative stress and inflammation in subjects with mild and moderate Alzheimer’s disease: a randomized, double-blind, placebo-controlled study
- Original Article
Camellia Akhgarjand, Zahra Vahabi, Sakineh Shab-Bidar, Aliarash Anoushirvani, Kurosh Djafarian
PI3K/AKT signaling activation by roflumilast ameliorates rotenone-induced Parkinson’s disease in rats
- Open Access
- Original Article
Heba A. Farid, Rabab H. Sayed, Marwa El-Sayed El-Shamarka, Omar M. E. Abdel-Salam, Nesrine S. El Sayed
Evaluation of the biological efficiency of Terminalia chebula fruit extract against neurochemical changes induced in brain of diabetic rats: an epigenetic study
- Open Access
- Original Article
Marwa E. A. El-Shamarka, Wael Mahmoud Aboulthana, Nagwa Ibrahim Omar, Marwa M. Mahfouz
Rosavin thwarts amyloid-β-induced macromolecular damages and neurotoxicity, exhibiting anti-Alzheimer’s disease activity in Wister rat model
- Original Article
Meiyi Huang, Rubo Sui, Lei Zhang, Yue Zhu, Xueling Yuan, Hongxin Jiang, Xin Mao
Liensinine reduces acute lung injury brought on by lipopolysaccharide by inhibiting the activation of the NF-κB signaling pathway through modification of the Src/TRAF6/TAK1 axis
- Original Article
Huizhen Chen, Feixue Liu, Dapeng Dai, Yuanyuan Ming, Yao Xu, Zhengqian Huang, Le Zhang, Yong Sun
Anti-inflammatory potential of some eudesmanolide and guaianolide sesquiterpenes
- Original Article
Shagufta Perveen, Azadeh Hamedi, Ardalan Pasdaran, Reza Heidari, Muhammad Shafiq ul Azam, Sobia Tabassum, Rashad Mehmood, Jiangnan Peng
Neuroprotective effect of curcumin against experimental autoimmune encephalomyelitis-induced cognitive and physical impairments in mice: an insight into the role of the AMPK/SIRT1 pathway
- Open Access
- Original Article
Mohamed A. Sadek, Mostafa A. Rabie, Nesrine S. El Sayed, Helmy M. Sayed, Esraa A. Kandil
Neuropeptide W facilitates chronic gastric ulcer healing by the regulation of cyclooxygenase and NF-κB signaling pathways
- Open Access
- Original Article
Sevil Arabacı Tamer, Kadriye Sezen Mermer, Ömer Erdoğan, Özge Çevik, Feriha Ercan, Cahit Bağcı, Berrak Ç. Yeğen
Hexahydrocurcumin attenuated demyelination and improved cognitive impairment in chronic cerebral hypoperfusion rats
- Original Article
Pranglada Jearjaroen, Phakkawat Thangwong, Chainarong Tocharus, Waraluck Chaichompoo, Apichart Suksamrarn, Jiraporn Tocharus
Neuroprotective mechanism of trans,trans-Farnesol in an ICV-STZ-induced rat model of Alzheimer’s pathology
- Original Article
Monika Kadian, Neetu Saini, Alka Khera, Anil Kumar
Aquaporins (AQPs) as a marker in the physiology of inflammation and its interaction studies with garcinol
- Original Article
Anuradha Kalita, Manas Das
Phytochemical profiling, antioxidant, cytotoxic, and anti-inflammatory activities of Plectranthus rugosus extract and fractions: in vitro, in vivo, and in silico approaches
- Original Article
Reyaz Hassan Mir, Roohi Mohi-ud-din, Lamya Ahmed Al-Keridis, Bilal Ahmad, Nawaf Alshammari, Mitesh Patel, Mohd Adnan, Mubashir Hussain Masoodi
Leaf extracts of eight selected southern African medicinal plants modulate pro-inflammatory cytokine secretion in LPS-stimulated RAW 264.7 macrophages
- Open Access
- Original Article
Gugulethu P. Khumalo, Wendy Loa-Kum-Cheung, Ben-Erik Van Wyk, Yunjiang Feng, Ian E. Cock
Phytochemical analysis and immunomodulatory activities in vitro and in vivo of Aframomum melegueta K Schum seed extracts
- Original Article
Mounia Latif, Ismail Elkoraichi, Othman El Faqer, Hicham Wahnou, El Mostafa Mtairag, Mounia Oudghiri, Samira Rais
Celecoxib attenuates hindlimb unloading-induced muscle atrophy via suppressing inflammation, oxidative stress and ER stress by inhibiting STAT3
- Original Article
Yanan Ji, Junfei Lin, Ruiqi Liu, Kexin Wang, Mengyuan Chang, Zihui Gao, Boya Liu, Yuntian Shen, Jianwei Zhu, Xinlei Yao, Lei Qi, Hualin Sun
Correction to: Melatonin ameliorates osteoarthritis rat cartilage injury by inhibiting matrix metalloproteinases and JAK2/STAT3 signaling pathway
- Correction
Zhongyuan Zhao, Benjun Bi, Gong Cheng, Yuchi Zhao, Hao Wu, Mingdi Zheng, Zhilin Cao
Correction: Cardiovascular effect of inflammation and nonsteroidal anti-inflammatory drugs on renin–angiotensin system in experimental arthritis
- Correction
Waheed Asghar, Ali Aghazadeh-Habashi, Fakhreddin Jamali
Correction: L-Carnitine augments probenecid anti-inflammatory effect in monoiodoacetate-induced knee osteoarthritis in rats: involvement of miRNA-373/P2X7/NLRP3/NF-κB milieu
- Open Access
- Correction
Rawan Mahfouz, Safaa H. El-Rewini, Asser I. Ghoneim, Eman Sheta, Mennatallah A. Ali, Sherihan Salaheldin Abdelhamid Ibrahim
Correction to: Chrysophanol exerts a protective effect against Aβ25‑35‑induced Alzheimer’s disease model through regulating the ROS/TXNIP/NLRP3 pathway
- Correction
Meng Zhang, Zhi‑xian Ding, Wei Huang, Jing Luo, Shu Ye, Sheng‑lin Hu, Peng Zhou, Biao Cai
Correction: Curcumin potentiates the anti-inflammatory effects of Tehranolide by modulating the STAT3/NF-κB signaling pathway in breast and ovarian cancer cell lines
- Correction
Havva Afshari, Shokoofe Noori, Afshin Zarghi