Ausgabe 1/2015
Inhalt (132 Artikel)
Galectin-3 mediates bone marrow microenvironment-induced drug resistance in acute leukemia cells via Wnt/β-catenin signaling pathway
Kaimin Hu, Yanjun Gu, Lixia Lou, Lizhen Liu, Yongxian Hu, Binsheng Wang, Yi Luo, Jimin Shi, Xiaohong Yu, He Huang
Evaluation of the anti-tumor effects of lactate dehydrogenase inhibitor galloflavin in endometrial cancer cells
Xiaoyun Han, Xiugui Sheng, Hannah M Jones, Amanda L Jackson, Joshua Kilgore, Jessica E Stine, Monica N Schointuch, Chunxiao Zhou, Victoria L Bae-Jump
IGF-IR determines the fates of BCR/ABL leukemia
Jingjing Xie, Xiaoli Chen, Junke Zheng, Chunling Li, Satomi Stacy, Martin Holzenberger, Xuemei Hu, Cheng Cheng Zhang
Non-myeloablative allogeneic hematopoietic cell transplantation following fludarabine plus 2 Gy TBI or ATG plus 8 Gy TLI: a phase II randomized study from the Belgian Hematological Society
Frédéric Baron, Pierre Zachée, Johan Maertens, Tessa Kerre, Aurélie Ory, Laurence Seidel, Carlos Graux, Philippe Lewalle, Michel Van Gelder, Koen Theunissen, Evelyne Willems, Marie-Paule Emonds, Ann De Becker, Yves Beguin
Persistent molecular remission of refractory acute myeloid leukemia with inv(16)(p13.1q22) in an elderly patient induced by cytarabine ocfosfate hydrate
Masahisa Arahata, Yukihiro Shimizu, Hidesaku Asakura, Shinji Nakao
MicroRNAs in pediatric central nervous system embryonal neoplasms: the known unknown
Maria Braoudaki, George I Lambrou
Loss of Angiopoietin-like 7 diminishes the regeneration capacity of hematopoietic stem and progenitor cells
Yiren Xiao, Xinru Wei, Zhiwu Jiang, Xiangmeng Wang, Wei Ye, Xin Liu, Minjie Zhang, Yan Xu, Donghai Wu, Liangxue Lai, Huihui Yao, Zixia Liu, Su Cao, Pentao Liu, Bing Xu, Yangqiu Li, Yao Yao, Duanqing Pei, Peng Li
Hematology research output from Chinese authors and other countries: a 10-year survey of the literature
Lei Zhang, Xin Ye, Yi Sun, An-mei Deng, Bao-hua Qian
Notch1 phenotype and clinical stage progression in non-small cell lung cancer
Dat Nguyen, Larry Rubinstein, Naoko Takebe, Lucio Miele, Joseph E Tomaszewski, Percy Ivy, James H Doroshow, Sherry X Yang
Insulin like growth factor binding protein 7 (IGFBP7) expression is linked to poor prognosis but may protect from bone disease in multiple myeloma
Arnold Bolomsky, Dirk Hose, Martin Schreder, Anja Seckinger, Susanne Lipp, Bernard Klein, Daniel Heintel, Heinz Ludwig, Niklas Zojer
High expression of neuroguidin increases the sensitivity of acute myeloid leukemia cells to chemotherapeutic drugs
Kejun Chen, Shuqing Lü, Hui Cheng, Gusheng Tang, Min Liu, Hong Zhou, Jianmin Wang
Role of microRNA in chronic lymphocytic leukemia onset and progression
Veronica Balatti, Yuri Pekarky, Carlo M Croce
Soluble NKG2D ligand promotes MDSC expansion and skews macrophage to the alternatively activated phenotype
Gang Xiao, Xuanjun Wang, Jun Sheng, Shengjun Lu, Xuezhong Yu, Jennifer D Wu
Transfer of microRNAs by extracellular membrane microvesicles: a nascent crosstalk model in tumor pathogenesis, especially tumor cell-microenvironment interactions
Li Zhang, C Alexander Valencia, Biao Dong, Meng Chen, Pu-Jun Guan, Ling Pan
DNA methyltransferase 1 functions through C/ebpa to maintain hematopoietic stem and progenitor cells in zebrafish
Xiaohui Liu, Xiaoe Jia, Hao Yuan, Ke Ma, Yi Chen, Yi Jin, Min Deng, Weijun Pan, Saijuan Chen, Zhu Chen, Hugues de The, Leonard I Zon, Yi Zhou, Jun Zhou, Jun Zhu
Cancer stem cells in basic science and in translational oncology: can we translate into clinical application?
Axel Schulenburg, Katharina Blatt, Sabine Cerny-Reiterer, Irina Sadovnik, Harald Herrmann, Brigitte Marian, Thomas W Grunt, Christoph C Zielinski, Peter Valent
Novel ALK inhibitors in clinical use and development
Chaitanya Iragavarapu, Milaim Mustafa, Akintunde Akinleye, Muhammad Furqan, Varun Mittal, Shundong Cang, Delong Liu
AntiCD3Fv fused to human interleukin-3 deletion variant redirected T cells against human acute myeloid leukemic stem cells
Dongmei Fan, Zhenzhen Li, Xiaolong Zhang, Yuqi Yang, Xiangfei Yuan, Xiuli Zhang, Ming Yang, Yizhi Zhang, Dongsheng Xiong
Journal of Hematology & Oncology reviewer acknowledgement 2014
Delong Liu, Thalyana Smith-Vikos
Expression and role of RIP140/NRIP1 in chronic lymphocytic leukemia
Marion Lapierre, Audrey Castet-Nicolas, Delphine Gitenay, Stéphan Jalaguier, Catherine Teyssier, Caroline Bret, Guillaume Cartron, Jérôme Moreaux, Vincent Cavaillès
Local administration of a novel Toll-like receptor 7 agonist in combination with doxorubicin induces durable tumouricidal effects in a murine model of T cell lymphoma
Jiang Zhu, Shiping He, Jie Du, Zhulin Wang, Wang Li, Xianxiong Chen, Wenqi Jiang, Duo Zheng, Guangyi Jin
Alpha-enolase promotes cell glycolysis, growth, migration, and invasion in non-small cell lung cancer through FAK-mediated PI3K/AKT pathway
Qiao-Fen Fu, Yan Liu, Yue Fan, Sheng-Ni Hua, Hong-Ying Qu, Su-Wei Dong, Rui-Lei Li, Meng-Yang Zhao, Yan Zhen, Xiao-Li Yu, Yi-Yu Chen, Rong-Cheng Luo, Rong Li, Li-Bo Li, Xiao-Jie Deng, Wei-Yi Fang, Zhen Liu, Xin Song
Coexpression of gene Oct4 and Nanog initiates stem cell characteristics in hepatocellular carcinoma and promotes epithelial-mesenchymal transition through activation of Stat3/Snail signaling
Xin Yin, Bo-Heng Zhang, Su-Su Zheng, Dong-Mei Gao, Shuang-Jian Qiu, Wei-Zhong Wu, Zheng-Gang Ren
Trogocytic intercellular membrane exchanges among hematological tumors
Joel LeMaoult, Julien Caumartin, Marina Daouya, Magdalena Switala, Vera Rebmann, Bertrand Arnulf, Edgardo D Carosella
VSTM-v1, a potential myeloid differentiation antigen that is downregulated in bone marrow cells from myeloid leukemia patients
Min Xie, Ting Li, Ning Li, Jinlan Li, Qiumei Yao, Wenling Han, Guorui Ruan
Aloperine executes antitumor effects against multiple myeloma through dual apoptotic mechanisms
He Wang, Shu Yang, Hong Zhou, Mingna Sun, Lingran Du, Minyan Wei, Meixia Luo, Jingzhu Huang, Hongzhu Deng, Yinghong Feng, Jun Huang, Yi Zhou
Pass quantity, focus on quality
Delong Liu, Weijing Sun, Jingzhou Hou, Ruirong Yuan, Zihai Li
EVI1 promotes tumor growth via transcriptional repression of MS4A3
Gerwin Heller, Anna Rommer, Katarina Steinleitner, Julia Etzler, Hubert Hackl, Petra Heffeter, Erwin Tomasich, Martin Filipits, Birgit Steinmetz, Thais Topakian, Simone Klingenbrunner, Barbara Ziegler, Andreas Spittler, Sabine Zöchbauer-Müller, Walter Berger, Rotraud Wieser
Zebrafish as a model for leukemia and other hematopoietic disorders
Parisa Rasighaemi, Faiza Basheer, Clifford Liongue, Alister C Ward
Competing endogenous RNA networks: tying the essential knots for cancer biology and therapeutics
Avencia Sanchez-Mejias, Yvonne Tay
RNA-guided CRISPR-Cas technologies for genome-scale investigation of disease processes
Sean E Humphrey, Andrea L Kasinski
Chromosomal rearrangement involving 11q23 locus in chronic myelogenous leukemia: a rare phenomenon frequently associated with disease progression and poor prognosis
Wei Wang, Guilin Tang, Jorge E Cortes, Hui Liu, Di Ai, C Cameron Yin, Shaoying Li, Joseph D Khoury, Carlos Bueso-Ramos, L Jeffrey Medeiros, Shimin Hu
Endothelial progenitor cells in ischemic stroke: an exploration from hypothesis to therapy
Ya-Feng Li, Li-Na Ren, Geng Guo, Lee Anne Cannella, Valeria Chernaya, Sonia Samuel, Su-Xuan Liu, Hong Wang, Xiao-Feng Yang
Alteration of gene expression profile following PPP2R5C knockdown may be associated with proliferation suppression and increased apoptosis of K562 cells
Sichu Liu, Qi Shen, Yu Chen, Chengwu Zeng, Changshu Cao, Lijian Yang, Shaohua Chen, Xiuli Wu, Bo Li, Yangqiu Li
A novel vaccine for mantle cell lymphoma based on targeting cyclin D1 to dendritic cells via CD40
Jingtao Chen, Gerard Zurawski, Sandy Zurawski, Zhiqing Wang, Keiko Akagawa, Sangkon Oh, Ueno Hideki, Joseph Fay, Jacques Banchereau, Wenru Song, A Karolina Palucka
TIM-3/Gal-9 interaction induces IFNγ-dependent IDO1 expression in acute myeloid leukemia blast cells
Valentina Folgiero, Loredana Cifaldi, Giuseppina Li Pira, Bianca Maria Goffredo, Luciana Vinti, Franco Locatelli
The non-peptide thrombopoietin receptor agonist eltrombopag stimulates megakaryopoiesis in bone marrow cells from patients with relapsed multiple myeloma
Jee-Yeong Jeong, Michelle S Levine, Nirmalee Abayasekara, Nancy Berliner, Jacob Laubach, Gary J Vanasse
piRNA involvement in genome stability and human cancer
Miguel Moyano, Giovanni Stefani
YM155 potently kills acute lymphoblastic leukemia cells through activation of the DNA damage pathway
Bill H Chang, Kara Johnson, Dorian LaTocha, Joelle S J Rowley, Jade Bryant, Russell Burke, Rebecca L Smith, Marc Loriaux, Markus Müschen, Charles Mullighan, Brian J Druker, Jeffrey W Tyner
Heat shock factor 1 is a potent therapeutic target for enhancing the efficacy of treatments for multiple myeloma with adverse prognosis
Sophie Bustany, Julie Cahu, Géraldine Descamps, Catherine Pellat-Deceunynck, Brigitte Sola
Oroxylin A promotes PTEN-mediated negative regulation of MDM2 transcription via SIRT3-mediated deacetylation to stabilize p53 and inhibit glycolysis in wt-p53 cancer cells
Kai Zhao, Yuxin Zhou, Chen Qiao, Ting Ni, Zhiyu Li, Xiaotang Wang, Qinglong Guo, Na Lu, Libin Wei
Deep sequencing and SNP array analyses of pediatric T-cell acute lymphoblastic leukemia reveal NOTCH1 mutations in minor subclones and a high incidence of uniparental isodisomies affecting CDKN2A
Kristina Karrman, Anders Castor, Mikael Behrendtz, Erik Forestier, Linda Olsson, Mats Ehinger, Andrea Biloglav, Thoas Fioretos, Kajsa Paulsson, Bertil Johansson
The long non-coding RNA, GAS5, enhances gefitinib-induced cell death in innate EGFR tyrosine kinase inhibitor-resistant lung adenocarcinoma cells with wide-type EGFR via downregulation of the IGF-1R expression
Siyuan Dong, Xiaohan Qu, Wenya Li, Xinwen Zhong, Peiwen Li, Shize Yang, Xitao Chen, Mingrui Shao, Lin Zhang
Novel approaches in the management of pancreatic ductal adenocarcinoma: potential promises for the future
Gaurav Goel, Weijing Sun
TP53 mutation characteristics in therapy-related myelodysplastic syndromes and acute myeloid leukemia is similar to de novo diseases
Chi Young Ok, Keyur P Patel, Guillermo Garcia-Manero, Mark J Routbort, Jie Peng, Guilin Tang, Maitrayee Goswami, Ken H Young, Rajesh Singh, L Jeffrey Medeiros, Hagop M Kantarjian, Rajyalakshmi Luthra, Sa A Wang
Azacytidine sensitizes acute myeloid leukemia cells to arsenic trioxide by up-regulating the arsenic transporter aquaglyceroporin 9
David Chau, Karen Ng, Thomas Sau-Yan Chan, Yuen-Yee Cheng, Bonnie Fong, Sidney Tam, Yok-Lam Kwong, Eric Tse
F-BAR family proteins, emerging regulators for cell membrane dynamic changes—from structure to human diseases
Suxuan Liu, Xinyu Xiong, Xianxian Zhao, Xiaofeng Yang, Hong Wang
Clinical significance of day 5 peripheral blast clearance rate in the evaluation of early treatment response and prognosis of patients with acute myeloid leukemia
Cong Yu, Qing-lei Kong, Yun-xiang Zhang, Xiang-qin Weng, Jing Wu, Yan Sheng, Chun-lei Jiang, Yong-mei Zhu, Qi Cao, Shu-min Xiong, Jun-min Li, Xiao-dong Xi, Sai-juan Chen, Bing Chen
The serum CXCL13 level is associated with the Glasgow Prognostic Score in extranodal NK/T-cell lymphoma patients
Seok Jin Kim, Kyung Ju Ryu, Mineui Hong, Young Hyeh Ko, Won Seog Kim
Long non-coding RNA ANRIL is upregulated in hepatocellular carcinoma and regulates cell apoptosis by epigenetic silencing of KLF2
Ming-de Huang, Wen-ming Chen, Fu-zhen Qi, Rui Xia, Ming Sun, Tong-peng Xu, Li Yin, Er-bao Zhang, Wei De, Yong-qian Shu
Improved disease markers suggest dual response in a patient with metastatic castration resistant prostate cancer and chronic lymphocytic leukemia following active cellular immunotherapy
Heather H. Cheng, Colleen Soleau, Evan Y. Yu
The impact of taxane-based preoperative chemotherapy in gastroesophageal signet ring cell adenocarcinomas
Stefano Kim, Frederic Fiteni, Sophie Paget-Bailly, François Ghiringhelli, Zaher Lakkis, Marine Jary, Francine Fein, Franck Bonnetain, Christophe Mariette, Christophe Borg
Role of gonadotropin-releasing hormone analogues in metastatic male breast cancer: results from a pooled analysis
Luigi Di Lauro, Laura Pizzuti, Maddalena Barba, Domenico Sergi, Isabella Sperduti, Marcella Mottolese, Carla Azzurra Amoreo, Franca Belli, Patrizia Vici, Valerie Speirs, Daniele Santini, Ruggero De Maria, Marcello Maugeri-Saccà
Phase II study of biomarker-guided neoadjuvant treatment strategy for IIIA-N2 non-small cell lung cancer based on epidermal growth factor receptor mutation status
Wenzhao Zhong, Xuening Yang, Honghong Yan, Xuchao Zhang, Jian Su, Zhihong Chen, Riqiang Liao, Qiang Nie, Song Dong, Qing Zhou, Jinji Yang, Haiyan Tu, Yi-Long Wu
Mutation analysis of Chinese sporadic congenital sideroblastic anemia by targeted capture sequencing
Wenbin An, Jingliao Zhang, Lixian Chang, Yingchi Zhang, Yang Wan, Yuanyuan Ren, Deyun Niu, Jian Wu, Xiaofan Zhu, Ye Guo
microRNA-26a suppresses recruitment of macrophages by down-regulating macrophage colony-stimulating factor expression through the PI3K/Akt pathway in hepatocellular carcinoma
Zong-Tao Chai, Xiao-Dong Zhu, Jian-Yang Ao, Wen-Quan Wang, Dong-Mei Gao, Jian Kong, Ning Zhang, Yuan-Yuan Zhang, Bo-Gen Ye, De-Ning Ma, Hao Cai, Hui-Chuan Sun
Long non-coding RNA ANRIL is upregulated in hepatocellular carcinoma and regulates cell proliferation by epigenetic silencing of KLF2
Ming-de Huang, Wen-ming Chen, Fu-zhen Qi, Rui Xia, Ming Sun, Tong-peng Xu, Li Yin, Er-bao Zhang, Wei De, Yong-qian Shu
HER2/neu-directed therapy for biliary tract cancer
Milind Javle, Chaitanya Churi, HyunSeon C. Kang, Rachna Shroff, Filip Janku, Rakesh Surapaneni, Mingxin Zuo, Christian Barrera, Humaid Alshamsi, Sunil Krishnan, Lopa Mishra, Robert A. Wolff, Ahmed O. Kaseb, Melanie B. Thomas, Abby B. Siegel
Quantitative evaluation of the immunodeficiency of a mouse strain by tumor engraftments
Wei Ye, Zhiwu Jiang, Guan-Xiong Li, Yiren Xiao, Simiao Lin, Yunxin Lai, Suna Wang, Baiheng Li, Bei Jia, Yin Li, Zhi-liang Huang, Jin Li, Fenglan Feng, Shuhua Li, Huihui Yao, Zixia Liu, Su Cao, Lin Xu, Yangqiu Li, Donghai Wu, Lingwen Zeng, Mei Zhong, Pentao Liu, Zhe-sheng Wen, Bing Xu, Yao Yao, Duanqing Pei, Peng Li
Targeting neoplastic B cells and harnessing microenvironment: the “double face” of ibrutinib and idelalisib
Rossana Maffei, Stefania Fiorcari, Silvia Martinelli, Leonardo Potenza, Mario Luppi, Roberto Marasca
Methotrexate resistance in relation to treatment outcome in childhood acute lymphoblastic leukemia
Anna Wojtuszkiewicz, Godefridus J. Peters, Nicole L. van Woerden, Boas Dubbelman, Gabriele Escherich, Kjeld Schmiegelow, Edwin Sonneveld, Rob Pieters, Peter M. van de Ven, Gerrit Jansen, Yehuda G. Assaraf, Gertjan J. L. Kaspers, Jacqueline Cloos
Evaluation of targeting c-Src by the RGT-containing peptide as a novel antithrombotic strategy
Jiansong Huang, Xiaofeng Shi, Wenda Xi, Ping Liu, Zhangbiao Long, Xiaodong Xi
Targeting Wnt pathway in mantle cell lymphoma-initiating cells
Rohit Mathur, Lalit Sehgal, Frank K. Braun, Zuzana Berkova, Jorge Romaguerra, Michael Wang, M. Alma Rodriguez, Luis Fayad, Sattva S. Neelapu, Felipe Samaniego
Angptl4 is upregulated under inflammatory conditions in the bone marrow of mice, expands myeloid progenitors, and accelerates reconstitution of platelets after myelosuppressive therapy
Anne Schumacher, Bernd Denecke, Till Braunschweig, Jasmin Stahlschmidt, Susanne Ziegler, Lars-Ove Brandenburg, Matthias B. Stope, Antons Martincuks, Michael Vogt, Dieter Görtz, Annalisa Camporeale, Valeria Poli, Gerhard Müller-Newen, Tim H. Brümmendorf, Patrick Ziegler
Stage, age, and EBV status impact outcomes of plasmablastic lymphoma patients: a clinicopathologic analysis of 61 patients
Sanam Loghavi, Khaled Alayed, Tariq N. Aladily, Zhuang Zuo, Siok-Bian Ng, Guilin Tang, Shimin Hu, C. Cameron Yin, Roberto N. Miranda, L. Jeffrey Medeiros, Joseph D. Khoury
STUMP un“stumped”: anti-tumor response to anaplastic lymphoma kinase (ALK) inhibitor based targeted therapy in uterine inflammatory myofibroblastic tumor with myxoid features harboring DCTN1-ALK fusion
Vivek Subbiah, Caitlin McMahon, Shreyaskumar Patel, Ralph Zinner, Elvio G Silva, Julia A. Elvin, Ishwaria M. Subbiah, Chimela Ohaji, Dhakshina Moorthy Ganeshan, Deepa Anand, Charles F. Levenback, Jenny Berry, Tim Brennan, Juliann Chmielecki, Zachary R. Chalmers, John Mayfield, Vincent A. Miller, Philip J. Stephens, Jeffrey S. Ross, Siraj M. Ali
Knockdown of SUMO-activating enzyme subunit 2 (SAE2) suppresses cancer malignancy and enhances chemotherapy sensitivity in small cell lung cancer
Xiaoke Liu, Yong Xu, Zongguo Pang, Fuchun Guo, Qing Qin, Tao Yin, Yaxiong Sang, Chengjun Feng, Xiaoyu Li, Li Jiang, Pei Shu, Yongsheng Wang
MiRNA-based therapeutic intervention of cancer
Srivatsava Naidu, Peter Magee, Michela Garofalo
Identification of the NUP98-PHF23 fusion gene in pediatric cytogenetically normal acute myeloid leukemia by whole-transcriptome sequencing
Marco Togni, Riccardo Masetti, Martina Pigazzi, Annalisa Astolfi, Daniele Zama, Valentina Indio, Salvatore Serravalle, Elena Manara, Valeria Bisio, Carmelo Rizzari, Giuseppe Basso, Andrea Pession, Franco Locatelli
Multiparameter analysis of homogeneously R-CHOP-treated diffuse large B cell lymphomas identifies CD5 and FOXP1 as relevant prognostic biomarkers: report of the prospective SAKK 38/07 study
Alexandar Tzankov, Nora Leu, Simone Muenst, Darius Juskevicius, Dirk Klingbiel, Christoph Mamot, Stephan Dirnhofer
Particulate cytoplasmic structures with high concentration of ubiquitin-proteasome accumulate in myeloid neoplasms
Alessandro Pecci, Vittorio Necchi, Serena Barozzi, Agostina Vitali, Emanuela Boveri, Chiara Elena, Paolo Bernasconi, Patrizia Noris, Enrico Solcia
Upregulated TCRζ improves cytokine secretion in T cells from patients with AML
Shaohua Chen, Xianfeng Zha, Li Shi, Lingling Zhou, Lijian Yang, Bo Li, Xiuli Wu, Jun Zhong, Tao Zhang, Yuhong Lu, Kanger Zhu, Yangqiu Li
Mutations in the D1 domain of von Willebrand factor impair their propeptide-dependent multimerization, intracellular trafficking and secretion
Jie Yin, Zhenni Ma, Jian Su, Jiong-Wei Wang, Xiaojuan Zhao, Jing Ling, Xia Bai, Wanyan Ouyang, Zhaoyue Wang, Ziqiang Yu, Changgeng Ruan
Waldenström macroglobulinemia with extramedullary involvement at initial diagnosis portends a poorer prognosis
Xin Cao, Qing Ye, Robert Z. Orlowski, Xiaoxiao Wang, Sanam Loghavi, Meifeng Tu, Sheeba K. Thomas, Jatin Shan, Shaoying Li, Muzaffar Qazilbash, C. Cameron Yin, Donna Weber, Roberto N. Miranda, Zijun Y. Xu-Monette, L. Jeffrey Medeiros, Ken H. Young
Sampling circulating tumor cells for clinical benefits: how frequent?
Sai Mun Leong, Karen ML Tan, Hui Wen Chua, Doreen Tan, Delly Fareda, Saabry Osmany, Mo-Huang Li, Steven Tucker, Evelyn SC Koay
Evaluation of hGM-CSF/hTNFα surface-modified prostate cancer therapeutic vaccine in the huPBL-SCID chimeric mouse model
Shouhua Lai, Zhiyong Huang, Yunting Guo, Yunqin Cui, Lei Wang, Weifeng Ren, Furong Ying, Hui Gao, Lingxia He, Tieli Zhou, Jiegen Jiang, Jimin Gao
High expression of endoplasmic reticulum chaperone grp94 is a novel molecular hallmark of malignant plasma cells in multiple myeloma
Saurabh Chhabra, Sandeep Jain, Caroline Wallace, Feng Hong, Bei Liu
Conditioning with rabbit versus horse ATG dramatically alters clinical outcomes in identical twins with severe aplastic anemia transplanted with the same allogeneic donor
P. T. Vo, J. Pantin, C. Ramos, L. Cook, E. Cho, R. Kurlander, H. Khuu, J. Barrett, S. Leitman, R. W. Childs
Platelet functional alterations in a Bernard-Soulier syndrome patient with filamin A mutation
Jiaming Li, KeSheng Dai, Zhaoyue Wang, Lijuan Cao, Xia Bai, Changgeng Ruan
Infused autograft lymphocyte-to-monocyte ratio and survival in T-cell lymphoma post-autologous peripheral blood hematopoietic stem cell transplantation
Luis F. Porrata, David J. Inwards, Stephen M. Ansell, Ivana N. Micallef, Patrick B. Johnston, William J. Hogan, Svetomir N. Markovic
In vitro and in vivo identification of ABCB1 as an efflux transporter of bosutinib
Sara Redaelli, Pietro Perini, Monica Ceccon, Rocco Piazza, Roberta Rigolio, Mario Mauri, Frank Boschelli, Athina Giannoudis, Carlo Gambacorti-Passerini
The synergic effect of vincristine and vorinostat in leukemia in vitro and in vivo
Min-Wu Chao, Mei-Jung Lai, Jing-Ping Liou, Ya-Ling Chang, Jing-Chi Wang, Shiow-Lin Pan, Che-Ming Teng
Exosomes in cancer: small particle, big player
Xu Zhang, Xiao Yuan, Hui Shi, Lijun Wu, Hui Qian, Wenrong Xu
Donor-specific anti-human leukocyte antigen antibodies were associated with primary graft failure after unmanipulated haploidentical blood and marrow transplantation: a prospective study with randomly assigned training and validation sets
Ying-Jun Chang, Xiang-Yu Zhao, Lan-Ping Xu, Xiao-Hui Zhang, Yu Wang, Wei Han, Huan Chen, Feng-Rong Wang, Xiao-Dong Mo, Yuan-Yuan Zhang, Ming-Rui Huo, Xiao-Su Zhao, Kong Y, Kai-Yan Liu, Xiao-Jun Huang
Advances in the management of gastrointestinal cancers—an upcoming role of immune checkpoint blockade
Gaurav Goel, Weijing Sun
Drugging the unfolded protein response in acute leukemias
Behzad Kharabi Masouleh, Eric Chevet, Jens Panse, Edgar Jost, Michael O’Dwyer, Tim H. Bruemmendorf, Afshin Samali
Role of DNA methylation in renal cell carcinoma
Niraj Shenoy, Nishanth Vallumsetla, Yiyu Zou, Jose Nahun Galeas, Makardhwaj Shrivastava, Caroline Hu, Katalin Susztak, Amit Verma
TMEM140 is associated with the prognosis of glioma by promoting cell viability and invasion
Bin Li, Ming-Zhu Huang, Xiao-Qiang Wang, Bang-Bao Tao, Jun Zhong, Xu-Hui Wang, Wen-Chuan Zhang, Shi-Ting Li
Favorable outcome of haploidentical hematopoietic stem cell transplantation in Philadelphia chromosome-positive acute lymphoblastic leukemia: a multicenter study in Southwest China
Li Gao, Cheng Zhang, Lei Gao, Yao Liu, Yi Su, Sanbin Wang, Bin Li, Tonghua Yang, Zhong Yuan, Xi Zhang
JAK kinase inhibitors for the treatment of acute lymphoblastic leukemia
Sandrine Degryse, Jan Cools
Ramucirumab, another anti-angiogenic agent for metastatic colorectal cancer in second-line setting—its impact on clinical practice
Gaurav Goel, Weijing Sun
T cells are functionally not impaired in AML: increased PD-1 expression is only seen at time of relapse and correlates with a shift towards the memory T cell compartment
Frauke M. Schnorfeil, Felix S. Lichtenegger, Katharina Emmerig, Miriam Schlueter, Julia S. Neitz, Rika Draenert, Wolfgang Hiddemann, Marion Subklewe
Haploinsufficiency of Bcl11b suppresses the progression of ATM-deficient T cell lymphomas
Kerice A. Pinkney, Wenxia Jiang, Brian J. Lee, Denis G. Loredan, Chen Li, Govind Bhagat, Shan Zha
Non-invasive approaches to monitor EGFR-TKI treatment in non-small-cell lung cancer
Wei Sun, Xun Yuan, Yijun Tian, Hua Wu, Hanxiao Xu, Guoqing Hu, Kongming Wu
AFM13: a first-in-class tetravalent bispecific anti-CD30/CD16A antibody for NK cell-mediated immunotherapy
Jingjing Wu, Jiaping Fu, Mingzhi Zhang, Delong Liu
Anti-leukemic activity of axitinib against cells harboring the BCR-ABL T315I point mutation
Seiichi Okabe, Tetsuzo Tauchi, Yuko Tanaka, Juri Sakuta, Kazuma Ohyashiki
Palbociclib: a first-in-class CDK4/CDK6 inhibitor for the treatment of hormone-receptor positive advanced breast cancer
Janice Lu
Genetically modified "obligate" anaerobic Salmonella typhimurium as a therapeutic strategy for neuroblastoma
Zhu-Ling Guo, Bin Yu, Bo-Tao Ning, Shing Chan, Qiu-Bin Lin, James Chun-Bong Li, Jian-Dong Huang, Godfrey Chi-Fung Chan
Establishment and genetic characterization of a novel mixed-phenotype acute leukemia cell line with EP300-ZNF384 fusion
Nana Ping, Huiying Qiu, Qian Wang, Haiping Dai, Changgeng Ruan, Stefan Ehrentraut, Hans G. Drexler, Roderick A. F. MacLeod, Suning Chen
Erratum: TMEM140 is associated with the prognosis of glioma by promoting cell viability and invasion
Bin Li, Ming-Zhu Huang, Xiao-Qiang Wang, Bang-Bao Tao, Jun Zhong, Xu-Hui Wang, Wen-Chuan Zhang, Shi-Ting Li
Clinical significance of high-dose cytarabine added to cyclophosphamide/total-body irradiation in bone marrow or peripheral blood stem cell transplantation for myeloid malignancy
Yasuyuki Arai, Kazunari Aoki, June Takeda, Tadakazu Kondo, Tetsuya Eto, Shuichi Ota, Hisako Hashimoto, Takahiro Fukuda, Yukiyasu Ozawa, Yoshinobu Kanda, Chiaki Kato, Mineo Kurokawa, Koji Iwato, Makoto Onizuka, Tatsuo Ichinohe, Yoshiko Atsuta, Akiyoshi Takami
Pharmacokinetics and safety of ixazomib plus lenalidomide–dexamethasone in Asian patients with relapsed/refractory myeloma: a phase 1 study
Neeraj Gupta, Yeow Tee Goh, Chang-Ki Min, Jae Hoon Lee, Kihyun Kim, Raymond S. M. Wong, Chor Sang Chim, Michael J. Hanley, Huyuan Yang, Karthik Venkatakrishnan, Ai-Min Hui, Dixie-Lee Esseltine, Wee Joo Chng
Blinatumomab: a bispecific T cell engager (BiTE) antibody against CD19/CD3 for refractory acute lymphoid leukemia
Jingjing Wu, Jiaping Fu, Mingzhi Zhang, Delong Liu
Effects of altered ephrin-A5 and EphA4/EphA7 expression on tumor growth in a medulloblastoma mouse model
Shilpa Bhatia, Kellen Hirsch, Nimrah A. Baig, Olga Rodriguez, Olga Timofeeva, Kevin Kavanagh, Yi Chien Lee, Xiao-Jing Wang, Christopher Albanese, Sana D. Karam
PTTG1 expression is associated with hyperproliferative disease and poor prognosis in multiple myeloma
Jacqueline E. Noll, Kate Vandyke, Duncan R. Hewett, Krzysztof M. Mrozik, Rachel J. Bala, Sharon A. Williams, Chung H. Kok, Andrew CW Zannettino
Unrelated cord blood transplantation for adult patients with acute myeloid leukemia: higher incidence of acute graft-versus-host disease and lower survival in male patients transplanted with female unrelated cord blood—a report from Eurocord, the Acute Leukemia Working Party, and the Cord Blood Committee of the Cellular Therapy and Immunobiology Working Party of the European Group for Blood and Marrow Transplantation
Frédéric Baron, Myriam Labopin, Annalisa Ruggeri, Mohamad Mohty, Guillermo Sanz, Noel Milpied, Andrea Bacigalupo, Alessandro Rambaldi, Francesca Bonifazi, Alberto Bosi, Jorge Sierra, Ibrahim Yakoub-Agha, Josep Maria Ribera Santasusana, Eliane Gluckman, Arnon Nagler
Redirection of CD4+ and CD8+ T lymphocytes via an anti-CD3 × anti-CD19 bi-specific antibody combined with cytosine arabinoside and the efficient lysis of patient-derived B-ALL cells
Dongmei Fan, Wei Li, Yuqi Yang, Xiaolong Zhang, Qing Zhang, Yan Yan, Ming Yang, Jianxiang Wang, Dongsheng Xiong
Comprehensive serial molecular profiling of an “N of 1” exceptional non-responder with metastatic prostate cancer progressing to small cell carcinoma on treatment
Kunal C. Kadakia, Scott A. Tomlins, Saagar K. Sanghvi, Andi K. Cani, Kei Omata, Daniel H. Hovelson, Chia-Jen Liu, Kathleen A. Cooney
All-trans retinoic acid arrests cell cycle in leukemic bone marrow stromal cells by increasing intercellular communication through connexin 43-mediated gap junction
Yao Liu, Qin Wen, Xue-lian Chen, Shi-jie Yang, Lei Gao, Li Gao, Cheng Zhang, Jia-li Li, Xi-xi Xiang, Kai Wan, Xing-hua Chen, Xi Zhang, Jiang-fan Zhong
Increase of PD-L1 expressing B-precursor ALL cells in a patient resistant to the CD19/CD3-bispecific T cell engager antibody blinatumomab
Thomas Köhnke, Christina Krupka, Johanna Tischer, Thomas Knösel, Marion Subklewe
Erratum to: The serum CXCL13 level is associated with the Glasgow Prognostic Score in extranodal NK/T-cell lymphoma patients
Seok Jin Kim, Kyung Ju Ryu, Mineui Hong, Young Hyeh Ko, Won Seog Kim
The roles of stem cell memory T cells in hematological malignancies
Ling Xu, Yikai Zhang, Gengxin Luo, Yangqiu Li
The Hedgehog pathway as targetable vulnerability with 5-azacytidine in myelodysplastic syndrome and acute myeloid leukemia
Raoul Tibes, Aref Al-Kali, Gavin R Oliver, Devora H Delman, Nanna Hansen, Keerthi Bhagavatula, Jayaram Mohan, Fariborz Rakhshan, Thomas Wood, James M. Foran, Ruben A. Mesa, James M. Bogenberger
High expression of myocyte enhancer factor 2C (MEF2C) is associated with adverse-risk features and poor outcome in pediatric acute myeloid leukemia: a report from the Children’s Oncology Group
George S. Laszlo, Todd A. Alonzo, Chelsea J. Gudgeon, Kimberly H. Harrington, Alex Kentsis, Robert B. Gerbing, Yi-Cheng Wang, Rhonda E. Ries, Susana C. Raimondi, Betsy A. Hirsch, Alan S. Gamis, Soheil Meshinchi, Roland B. Walter
Desialylation is associated with apoptosis and phagocytosis of platelets in patients with prolonged isolated thrombocytopenia after allo-HSCT
Xiao-Hui Zhang, Qian-Ming Wang, Jia-Min Zhang, Fei-Er Feng, Feng-Rong Wang, Huan Chen, Yuan-Yuan Zhang, Yu-Hong Chen, Wei Han, Lan-Ping Xu, Kai-Yan Liu, Xiao-Jun Huang
Small PARP inhibitor PJ-34 induces cell cycle arrest and apoptosis of adult T-cell leukemia cells
Xue Tao Bai, Ramona Moles, Hassiba Chaib-Mezrag, Christophe Nicot
Model-based adaptive phase I trial design of post-transplant decitabine maintenance in myelodysplastic syndrome
Seunghoon Han, Yoo-Jin Kim, Jongtae Lee, Sangil Jeon, Taegon Hong, Gab-jin Park, Jae-Ho Yoon, Seung-Ah Yahng, Seung-Hwan Shin, Sung-Eun Lee, Ki-Seong Eom, Hee-Je Kim, Chang-Ki Min, Seok Lee, Dong-Seok Yim
Complexity of FGFR signalling in metastatic urothelial cancer
Alejo Rodriguez-Vida, Matilde Saggese, Simon Hughes, Sarah Rudman, Simon Chowdhury, Neil R. Smith, Peter Lawrence, Claire Rooney, Brian Dougherty, Donal Landers, Elaine Kilgour, Hendrik-Tobias Arkenau
NLK functions to maintain proliferation and stemness of NSCLC and is a target of metformin
Dong Suwei, Zeng Liang, Liu Zhimin, Li Ruilei, Zou Yingying, Li Zhen, Ge Chunlei, Lai Zhangchao, Xue Yuanbo, Yang Jinyan, Li Gaofeng, Song Xin
Establishment and characterization of a novel MYC/BCL2 “double-hit” diffuse large B cell lymphoma cell line, RC
Lan V. Pham, Gary Lu, Archito T. Tamayo, Juan Chen, Pramoda Challagundla, Jeffrey L. Jorgensen, L. Jeffrey Medeiros, Richard J. Ford
Exosomes derived from miR-122-modified adipose tissue-derived MSCs increase chemosensitivity of hepatocellular carcinoma
Guohua Lou, Xiuli Song, Fan Yang, Shanshan Wu, Jing Wang, Zhi Chen, Yanning Liu
Nivolumab plus ipilimumab in the treatment of advanced melanoma
Katy K. Tsai, Adil I. Daud
Programmed death 1 blockade, an Achilles heel for MMR-deficient tumors?
Andy Yingjie Lin, Edward Lin
In vitro and in vivo single-agent efficacy of checkpoint kinase inhibition in acute lymphoblastic leukemia
Ilaria Iacobucci, Andrea Ghelli Luserna Di Rorà, Maria Vittoria Verga Falzacappa, Claudio Agostinelli, Enrico Derenzini, Anna Ferrari, Cristina Papayannidis, Annalisa Lonetti, Simona Righi, Enrica Imbrogno, Silvia Pomella, Claudia Venturi, Viviana Guadagnuolo, Federica Cattina, Emanuela Ottaviani, Maria Chiara Abbenante, Antonella Vitale, Loredana Elia, Domenico Russo, Pier Luigi Zinzani, Stefano Pileri, Pier Giuseppe Pelicci, Giovanni Martinelli
Overexpression of the long non-coding RNA PVT1 is correlated with leukemic cell proliferation in acute promyelocytic leukemia
Chengwu Zeng, Xibao Yu, Jing Lai, Lijiang Yang, Shaohua Chen, Yangqiu Li
Identification of plasma microRNA profiles for primary resistance to EGFR-TKIs in advanced non-small cell lung cancer (NSCLC) patients with EGFR activating mutation
Shuhang Wang, Xiaomei Su, Hua Bai, Jun Zhao, Jianchun Duan, Tongtong An, Minglei Zhuo, Zhijie Wang, Meina Wu, Zhenxiang Li, Jian Zhu, Jie Wang
Persistent androgen receptor addiction in castration-resistant prostate cancer
Michael T. Schweizer, Evan Y. Yu
ABT-199 (venetoclax) and BCL-2 inhibitors in clinical development
Shundong Cang, Chaitanya Iragavarapu, John Savooji, Yongping Song, Delong Liu
Bispecific antibodies and their applications
Gaowei Fan, Zujian Wang, Mingju Hao, Jinming Li
Erratum: Heritable GATA2 mutations associated with familial AML-MDS: a case report and review of literature
Juehua Gao, Ryan D. Gentzler, Andrew E. Timms, Marshall S. Horwitz, Olga Frankfurt, Jessica K. Altman, LoAnn C. Peterson
Roles of palmitoylation and the KIKK membrane-targeting motif in leukemogenesis by oncogenic KRAS4A
Huanbin Zhao, Ping Liu, Ruihong Zhang, Min Wu, Donghe Li, Xuemei Zhao, Chun Zhang, Bo Jiao, Bing Chen, Zhu Chen, Ruibao Ren