Ausgabe 1/2014
Inhalt (95 Artikel)
Phase 1 trial of the oral AKT inhibitor MK-2206 plus carboplatin/paclitaxel, docetaxel, or erlotinib in patients with advanced solid tumors
L Rhoda Molife, Li Yan, Joanna Vitfell-Rasmussen, Adriane M Zernhelt, Daniel M Sullivan, Philippe A Cassier, Eric Chen, Andrea Biondo, Ernestina Tetteh, Lillian L Siu, Amita Patnaik, Kyriakos P Papadopoulos, Johann S de Bono, Anthony W Tolcher, Susan Minton
Homoharringtonine and omacetaxine for myeloid hematological malignancies
Shuqing Lü, Jianmin Wang
Adoptive transfer of genetically engineered WT1-specific cytotoxic T lymphocytes does not induce renal injury
Hiroaki Asai, Hiroshi Fujiwara, Sohei Kitazawa, Naoto Kobayashi, Toshiki Ochi, Yukihiro Miyazaki, Fumihiro Ochi, Yoshiki Akatsuka, Sachiko Okamoto, Junichi Mineno, Kiyotaka Kuzushima, Hiroaki Ikeda, Hiroshi Shiku, Masaki Yasukawa
Differentially expressed microRNAs in the serum of cervical squamous cell carcinoma patients before and after surgery
Wen-Tao Wang, Ya-Nan Zhao, Jin-Xing Yan, Mei-Ying Weng, Yan Wang, Yue-Qin Chen, Shun-Jia Hong
Developing aptamer probes for acute myelogenous leukemia detection and surface protein biomarker discovery
Mingli Yang, Guohua Jiang, Wenjing Li, Kai Qiu, Min Zhang, Christopher M Carter, Samer Z Al-Quran, Ying Li
Interferon-γ-induced upregulation of immunoproteasome subunit assembly overcomes bortezomib resistance in human hematological cell lines
Denise Niewerth, Gertjan JL Kaspers, Yehuda G Assaraf, Johan van Meerloo, Christopher J Kirk, Janet Anderl, Jonathan L Blank, Peter M van de Ven, Sonja Zweegman, Gerrit Jansen, Jacqueline Cloos
Targeted therapy by combined inhibition of the RAF and mTOR kinases in malignant spindle cell neoplasm harboring the KIAA1549-BRAF fusion protein
Vivek Subbiah, Shannon N Westin, Kai Wang, Dejka Araujo, Wei-Lien Wang, Vincent A Miller, Jeffrey S Ross, Phillip J Stephens, Gary A Palmer, Siraj M Ali
Short-term efficacy of the IL6 receptor antibody tocilizumab in patients with HIV-associated multicentric Castleman disease: report of two cases
Azusa Nagao, Shoko Nakazawa, Hideji Hanabusa
Hypermethylation of the alternative AWT1 promoter in hematological malignancies is a highly specific marker for acute myeloid leukemias despite high expression levels
Amy Guillaumet-Adkins, Julia Richter, Maria D Odero, Juan Sandoval, Xabi Agirre, Albert Catala, Manel Esteller, Felipe Prósper, María José Calasanz, Ismael Buño, Mi Kwon, Franck Court, Reiner Siebert, David Monk
Journal of Hematology & Oncology reviewer acknowledgement 2013
Delong Liu
Signaling pathways in the development of infantile hemangioma
Yi Ji, Siyuan Chen, Kai Li, Li Li, Chang Xu, Bo Xiang
The roles of mesenchymal stem cells in tumor inflammatory microenvironment
Zhao Sun, Shihua Wang, Robert Chunhua Zhao
A novel mycobacterial Hsp70-containing fusion protein targeting mesothelin augments antitumor immunity and prolongs survival in murine models of ovarian cancer and mesothelioma
Jianping Yuan, Satoshi Kashiwagi, Patrick Reeves, Jean Nezivar, Yuan Yang, Nadiah Hashim Arrifin, Mai Nguyen, Gilberte Jean-Mary, Xiaoyun Tong, Paramjit Uppal, Svetlana Korochkina, Ben Forbes, Tao Chen, Elda Righi, Roderick Bronson, Huabiao Chen, Sandra Orsulic, Timothy Brauns, Pierre Leblanc, Nathalie Scholler, Glenn Dranoff, Jeffrey Gelfand, Mark C Poznansky
Pten regulates homeostasis and inflammation-induced migration of myelocytes in zebrafish
Zhi-Wei Dong, Chun-Guang Ren, Yu Xia, Dan Su, Ting-Ting Du, Hong-Bo Fan, Hao Yuan, Lei Wang, Mei Dong, Wei-Chun Li, Yi Jin, Yi Chen, Min Deng, Ting-Xi Liu, Ai-Hua Gu, Yong Zhou
Post-transcriptional regulatory network of epithelial-to-mesenchymal and mesenchymal-to-epithelial transitions
Fei Guo, Brittany C Parker Kerrigan, Da Yang, Limei Hu, Ilya Shmulevich, Anil K Sood, Fengxia Xue, Wei Zhang
Long-term results of a phase II study with neoadjuvant docetaxel chemotherapy and complete androgen blockade in locally advanced and high-risk prostate cancer
Mark Thalgott, Thomas Horn, Matthias M Heck, Tobias Maurer, Matthias Eiber, Margitta Retz, Michael Autenrieth, Kathleen Herkommer, Bernd J Krause, Jürgen E Gschwend, Uwe Treiber, Hubert R Kübler
Targeting hedgehog signaling in myelofibrosis and other hematologic malignancies
Raoul Tibes, Ruben A Mesa
Cysteine- rich secretory protein 3 (CRISP3), ERG and PTEN define a molecular subtype of prostate cancer with implication to patients’ prognosis
Samir Al Bashir, Mohammed Alshalalfa, Samar A Hegazy, Michael Dolph, Bryan Donnelly, Tarek A Bismar
CD44 standard and CD44v10 isoform expression on leukemia cells distinctly influences niche embedding of hematopoietic stem cells
Ulrike Erb, Amelie Pajip Megaptche, Xiaoyu Gu, Markus W Büchler, Margot Zöller
Randomized comparison of single dose of recombinant human IL-12 versus placebo for restoration of hematopoiesis and improved survival in rhesus monkeys exposed to lethal radiation
Zoya Gluzman-Poltorak, Sarita R Mendonca, Vladimir Vainstein, Hue Kha, Lena A Basile
Targeting xCT, a cystine-glutamate transporter induces apoptosis and tumor regression for KSHV/HIV-associated lymphoma
Lu Dai, Yueyu Cao, Yihan Chen, Chris Parsons, Zhiqiang Qin
A novel anti-CD19 monoclonal antibody (GBR 401) with high killing activity against B cell malignancies
Caroline S Breton, Aimable Nahimana, Dominique Aubry, Julie Macoin, Pierre Moretti, Martin Bertschinger, Samuel Hou, Michel A Duchosal, Jonathan Back
Discovery of imatinib-responsive FIP1L1-PDGFRA mutation during refractory acute myeloid leukemia transformation of chronic myelomonocytic leukemia
Shilpan Shah, Sanam Loghavi, Guillermo Garcia-Manero, Joseph D Khoury
Selective splenic artery embolization for the treatment of thrombocytopenia and hypersplenism in paroxysmal nocturnal hemoglobinuria
David J Araten, Anna Paola Iori, Karen Brown, Giovanni Fernando Torelli, Walter Barberi, Fiammetta Natalino, Maria Stefania De Propris, Corrado Girmenia, Filippo Maria Salvatori, Orly Zelig, Robin Foà, Lucio Luzzatto
Arsenic trioxide induces differentiation of CD133+ hepatocellular carcinoma cells and prolongs posthepatectomy survival by targeting GLI1 expression in a mouse model
Ke-Zhi Zhang, Qiang-Bo Zhang, Quan-Bao Zhang, Hui-Chuan Sun, Jian-Yang Ao, Zong-Tao Chai, Xiao-Dong Zhu, Lu Lu, Yuan-Yuan Zhang, Yang Bu, Ling-Qun Kong, Zhao-You Tang
Retreatment with brentuximab vedotin in patients with CD30-positive hematologic malignancies
Nancy L Bartlett, Robert Chen, Michelle A Fanale, Pauline Brice, Ajay Gopal, Scott E Smith, Ranjana Advani, Jeffrey V Matous, Radhakrishnan Ramchandren, Joseph D Rosenblatt, Dirk Huebner, Pamela Levine, Laurie Grove, Andres Forero-Torres
Cardiac hypertrophy associated with myeloproliferative neoplasms in JAK2V617F transgenic mice
Kaiyao Shi, Wanke Zhao, Yun Chen, Wanting Tina Ho, Ping Yang, Zhizhuang Joe Zhao
Structural determinants of human ζ-globin mRNA stability
Zhenning He, Decheng Song, Sebastiaan van Zalen, J Eric Russell
Clinical and genetic features of pediatric acute lymphoblastic leukemia in Down syndrome in the Nordic countries
Catarina Lundin, Erik Forestier, Mette Klarskov Andersen, Kirsi Autio, Gisela Barbany, Lucia Cavelier, Irina Golovleva, Sverre Heim, Kristiina Heinonen, Randi Hovland, Johann H Johannsson, Eigil Kjeldsen, Ann Nordgren, Lars Palmqvist, Bertil Johansson
The addition of rituximab to CHOP therapy alters the prognostic significance of CD44 expression
Xiaolei Wei, Meng Xu, Yongqiang Wei, Fen Huang, Tong Zhao, Xiangzhao Li, Ru Feng, B Hilda Ye
Heritable GATA2 mutations associated with familial AML-MDS: a case report and review of literature
Juehua Gao, Ryan D Gentzler, Andrew E Timms, Marshall S Horwitz, Olga Frankfurt, Jessica K Altman, LoAnn C Peterson
Combination of the ABL kinase inhibitor imatinib with the Janus kinase 2 inhibitor TG101348 for targeting residual BCR-ABL-positive cells
Seiichi Okabe, Tetsuzo Tauchi, Seiichiro Katagiri, Yuko Tanaka, Kazuma Ohyashiki
Antibodies reacting with Simian Virus 40 capsid protein mimotopes in serum samples from patients affected by uveal melanoma
Ilaria Bononi, Paolo Perri, Alice Begnardi, Alessandra Martini, Elisa Mazzoni, Silvia Bosi, Silvia Pietrobon, Adolfo Sebastiani, Mauro Tognon, Fernanda Martini
Argonaute 2 promotes myeloma angiogenesis via microRNA dysregulation
Shuang Wu, Wenjun Yu, Xiaoyan Qu, Rong Wang, Ji Xu, Qiguo Zhang, Jiaren Xu, Jianyong Li, Lijuan Chen
Synergistic effects of combined platelet-activating factor receptor and epidermal growth factor receptor targeting in ovarian cancer cells
Yi Yu, Mingxing Zhang, Xiaoyan Zhang, Qingqing Cai, Shanshan Hong, Wei Jiang, Congjian Xu
Electroacupuncture for thalidomide/bortezomib-induced peripheral neuropathy in multiple myeloma: a feasibility study
M Kay Garcia, Lorenzo Cohen, Ying Guo, Yuhong Zhou, Bing You, Joseph Chiang, Robert Z Orlowski, Donna Weber, Jatin Shah, Raymond Alexanian, Sheeba Thomas, Jorge Romaguera, Liang Zhang, Maria Badillo, Yiming Chen, Qi Wei, Richard Lee, Kay Delasalle, Vivian Green, Michael Wang
Identification of nuclear-enriched miRNAs during mouse granulopoiesis
Justin JL Wong, William Ritchie, Dadi Gao, Katherine A Lau, Maria Gonzalez, Anupma Choudhary, Ryan J Taft, John EJ Rasko, Jeff Holst
Polymorphisms in microRNA target sites modulate risk of lymphoblastic and myeloid leukemias and affect microRNA binding
Agnieszka Dzikiewicz-Krawczyk, Anna Macieja, Ewa Mały, Danuta Januszkiewicz-Lewandowska, Maria Mosor, Marta Fichna, Ewa Strauss, Jerzy Nowak
IMP3 signatures of fallopian tube: a risk for pelvic serous cancers
Yiying Wang, Yue Wang, Dake Li, Lingmin Li, Wenjing Zhang, Guang Yao, Zhong Jiang, Wenxin Zheng
Low expression of T-cell transcription factor BCL11b predicts inferior survival in adult standard risk T-cell acute lymphoblastic leukemia patients
Isabelle Bartram, Nicola Gökbuget, Cornelia Schlee, Sandra Heesch, Lars Fransecky, Stefan Schwartz, Reingard Stuhlmann, Kerstin Schäfer-Eckhart, Michael Starck, Albrecht Reichle, Dieter Hoelzer, Claudia D Baldus, Martin Neumann
High frequency of TERT promoter mutation in small cell carcinoma of bladder, but not in small cell carcinoma of other origins
Xiaoyong Zheng, Jian Zhuge, Stephania M Bezerra, Sheila F Faraj, Enrico Munari, John T Fallon, Ximing J Yang, Pedram Argani, George J Netto, Minghao Zhong
Advances in understanding the cell types and approaches used for generating induced pluripotent stem cells
Jun Li, Wei Song, Guangjin Pan, Jun Zhou
CHK1 plays a critical role in the anti-leukemic activity of the wee1 inhibitor MK-1775 in acute myeloid leukemia cells
Wenxiu Qi, Chengzhi Xie, Chunhuai Li, J Timothy Caldwell, Holly Edwards, Jeffrey W Taub, Yue Wang, Hai Lin, Yubin Ge
Toll-like receptors in the pathogenesis of human B cell malignancies
Johana M Isaza-Correa, Zheng Liang, Anke van den Berg, Arjan Diepstra, Lydia Visser
Next generation sequencing analysis of platinum refractory advanced germ cell tumor sensitive to Sunitinib (Sutent®) a VEGFR2/PDGFRβ/c-kit/ FLT3/RET/CSF1R inhibitor in a phase II trial
Vivek Subbiah, Funda Meric-Bernstam, Gordon B Mills, Kenna R Mills Shaw, Ann Marie Bailey, Priya Rao, John F Ward, Lance C Pagliaro
The role of telomeres and telomerase in hematologic malignancies and hematopoietic stem cell transplantation
Limengmeng Wang, Haowen Xiao, Xing Zhang, Chong Wang, He Huang
Small-molecule survivin inhibitor YM155 enhances radiosensitization in esophageal squamous cell carcinoma by the abrogation of G2 checkpoint and suppression of homologous recombination repair
Qin Qin, Hongyan Cheng, Jing Lu, Liangliang Zhan, Jianchao Zheng, Jing Cai, Xi Yang, Liping Xu, Hongcheng Zhu, Chi Zhang, Jia Liu, Jianxin Ma, Xizhi Zhang, Shengbin Dai, Xinchen Sun
Decreased expression of the long non-coding RNA FENDRR is associated with poor prognosis in gastric cancer and FENDRR regulates gastric cancer cell metastasis by affecting fibronectin1 expression
Tong-peng Xu, Ming-de Huang, Rui Xia, Xin-xin Liu, Ming Sun, Li Yin, Wen-ming Chen, Liang Han, Er-bao Zhang, Rong Kong, Wei De, Yong-qian Shu
Multicenter phase ii study of a combination of cyclosporine a, methotrexate and mycophenolate mofetil for GVHD prophylaxis: results of the Chinese Bone Marrow Transplant Cooperative Group (CBMTCG)
Yong-rong Lai, Yu-hong Chen, Deng-ming Hu, Ming Jiang, Qi-fa Liu, Lin Liu, Jian Hou, Paul Schwarzenberger, Qiao-chuan Li, Zhong-ming Zhang, Kai-yan Liu, Xiao-jun Huang
New antibody approaches to lymphoma therapy
Tejas Suresh, Lisa X Lee, Jitesh Joshi, Stefan K Barta
Mutated in colorectal cancer (MCC) is a novel oncogene in B lymphocytes
Shanique KE Edwards, Jacqueline Baron, Carissa R Moore, Yan Liu, David H Perlman, Ronald P Hart, Ping Xie
Long-term follow-up of cytogenetically normal CEBPA-mutated AML
Friederike Pastore, Daniela Kling, Eva Hoster, Annika Dufour, Nikola P Konstandin, Stephanie Schneider, Maria C Sauerland, Wolfgang E Berdel, Thomas Buechner, Bernhard Woermann, Jan Braess, Wolfgang Hiddemann, Karsten Spiekermann
Highly efficient, In-vivo Fas-mediated Apoptosis of B-cell Lymphoma by Hexameric CTLA4-FasL
Alexandra Aronin, Shira Amsili, Tatyana B Prigozhina, Kobi Tzdaka, Roy Shen, Leonid Grinmann, Fanny Szafer, Per Edebrink, Mari-Anne Rauvola, Noam Shani, Michal Dranitzki Elhalel
8q24 amplified segments involve novel fusion genes between NSMCE2 and long noncoding RNAs in acute myelogenous leukemia
Yoshiaki Chinen, Natsumi Sakamoto, Hisao Nagoshi, Tomohiko Taki, Saori Maegawa, Shotaro Tatekawa, Taku Tsukamoto, Shinsuke Mizutani, Yuji Shimura, Mio Yamamoto-Sugitani, Tsutomu Kobayashi, Yosuke Matsumoto, Shigeo Horiike, Junya Kuroda, Masafumi Taniwaki
CEBPA-regulated lncRNAs, new players in the study of acute myeloid leukemia
James M Hughes, Beatrice Salvatori, Federico M Giorgi, Irene Bozzoni, Alessandro Fatica
Lower circulating platelet counts and antiplatelet therapy independently predict better outcomes in patients with head and neck squamous cell carcinoma
Saleh Rachidi, Kristin Wallace, Terry A Day, Anthony J Alberg, Zihai Li
CBFB-MYH11 hypomethylation signature and PBX3 differential methylation revealed by targeted bisulfite sequencing in patients with acute myeloid leukemia
Hana Hájková, Markus Hsi-Yang Fritz, Cedrik Haškovec, Jiří Schwarz, Cyril Šálek, Jana Marková, Zdeněk Krejčík, Michaela Dostálová Merkerová, Arnošt Kostečka, Martin Vostrý, Ota Fuchs, Kyra Michalová, Petr Cetkovský, Vladimír Beneš
Catechins induced acute promyelocytic leukemia cell apoptosis and triggered PML-RARα oncoprotein degradation
Li Zhang, Qiu-Sheng Chen, Peng-Peng Xu, Ying Qian, Ai-Hua Wang, Dan Xiao, Yan Zhao, Yan Sheng, Xiang-Qin Wen, Wei-Li Zhao
T cell immune abnormalities in immune thrombocytopenia
Xuebin Ji, Liping Zhang, Jun Peng, Ming Hou
Strategies for modern biomarker and drug development in oncology
Alan D Smith, Desam Roda, Timothy A Yap
Clinical features of De Novo acute myeloid leukemia with concurrent DNMT3A, FLT3 and NPM1 mutations
Sanam Loghavi, Zhuang Zuo, Farhad Ravandi, Hagop M Kantarjian, Carlos Bueso-Ramos, Liping Zhang, Rajesh R Singh, Keyur P Patel, L Jeffrey Medeiros, Francesco Stingo, Mark Routbort, Jorge Cortes, Rajyalakshmi Luthra, Joseph D Khoury
SINE (selective inhibitor of nuclear export) – translational science in a new class of anti-cancer agents
John Gerecitano
Recurrent LRP1-SNRNP25 and KCNMB4-CCND3 fusion genes promote tumor cell motility in human osteosarcoma
Jilong Yang, Matti Annala, Ping Ji, Guowen Wang, Hong Zheng, David Codgell, Xiaoling Du, Zhiwei Fang, Baocun Sun, Matti Nykter, Kexin Chen, Wei Zhang
Selective inhibitors of nuclear export (SINE)– a novel class of anti-cancer agents
Kaushal Parikh, Shundong Cang, Arunabh Sekhri, Delong Liu
CSF3R, SETBP1 and CALR mutations in chronic neutrophilic leukemia
Yajuan Cui, Bing Li, Robert Peter Gale, Qian Jiang, Zefeng Xu, Tiejun Qin, Peihong Zhang, Yue Zhang, Zhijian Xiao
DACH1 inhibits cyclin D1 expression, cellular proliferation and tumor growth of renal cancer cells
Qian Chu, Na Han, Xun Yuan, Xin Nie, Hua Wu, Yu Chen, Mingzhou Guo, Shiying Yu, Kongming Wu
Potential therapeutic role of antagomiR17 for the treatment of chronic lymphocytic leukemia
Sara Dereani, Paolo Macor, Tiziana D’Agaro, Nelly Mezzaroba, Michele Dal-Bo, Sara Capolla, Antonella Zucchetto, Erika Tissino, Giovanni Del Poeta, Sonia Zorzet, Valter Gattei, Riccardo Bomben
Immunosuppressive/anti-inflammatory cytokines directly and indirectly inhibit endothelial dysfunction- a novel mechanism for maintaining vascular function
Ying Shao, Zhongjian Cheng, Xinyuan Li, Valeria Chernaya, Hong Wang, Xiao-feng Yang
Notch1-induced T cell leukemia can be potentiated by microenvironmental cues in the spleen
Shihui Ma, Yingxu Shi, Yakun Pang, Fang Dong, Hui Cheng, Sha Hao, Jing Xu, Xiaofan Zhu, Weiping Yuan, Tao Cheng, Guoguang Zheng
Constitutional and somatic deletions of the Williams-Beuren syndrome critical region in Non-Hodgkin Lymphoma
David Guenat, Samuel Quentin, Carmelo Rizzari, Catarina Lundin, Tiziana Coliva, Patrick Edery, Helen Fryssira, Laurent Bermont, Christophe Ferrand, Jean Soulier, Christophe Borg, Pierre-Simon Rohrlich
SWI/SNF proteins as targets in cancer therapy
Santiago Schiaffino-Ortega, Carlos Balinas, Marta Cuadros, Pedro P Medina
MicroRNA-binding site polymorphisms in hematological malignancies
Agnieszka Dzikiewicz-Krawczyk
MicroRNA-mediated regulation of KRAS in cancer
Minlee Kim, Frank J Slack
Nucleo-cytoplasmic transport as a therapeutic target of cancer
Giovanni Luca Gravina, William Senapedis, Dilara McCauley, Erkan Baloglu, Sharon Shacham, Claudio Festuccia
Circulating miRNAs in cancer: from detection to therapy
Wen-Tao Wang, Yue-Qin Chen
Notch signaling and EMT in non-small cell lung cancer: biological significance and therapeutic application
Xun Yuan, Hua Wu, Na Han, Hanxiao Xu, Qian Chu, Shiying Yu, Yuan Chen, Kongming Wu
c-FLIP is involved in tumor progression of peripheral T-cell lymphoma and targeted by histone deacetylase inhibitors
Zhong Zheng, Shu Cheng, Wen Wu, Li Wang, Yan Zhao, Yang Shen, Anne Janin, Wei-Li Zhao
Splicing factor 3b subunit 1 (Sf3b1) haploinsufficient mice display features of low risk Myelodysplastic syndromes with ring sideroblasts
Valeria Visconte, Ali Tabarroki, Li Zhang, Yvonne Parker, Edy Hasrouni, Reda Mahfouz, Kyoichi Isono, Haruhiko Koseki, Mikkael A Sekeres, Yogen Saunthararajah, John Barnard, Daniel Lindner, Heesun J Rogers, Ramon V Tiu
Pim kinases in hematological malignancies: where are we now and where are we going?
Patrizia Mondello, Salvatore Cuzzocrea, Michael Mian
Functions of lncRNA HOTAIR in lung cancer
Gregory Loewen, Janarthanan Jayawickramarajah, Ying Zhuo, Bin Shan
Molecular genetics of chronic neutrophilic leukemia, chronic myelomonocytic leukemia and atypical chronic myeloid leukemia
Bing Li, Robert Peter Gale, Zhijian Xiao
Activated fibronectin-secretory phenotype of mesenchymal stromal cells in pre-fibrotic myeloproliferative neoplasms
Rebekka K Schneider, Susanne Ziegler, Isabelle Leisten, Monica SV Ferreira, Anne Schumacher, Björn Rath, Dirk Fahrenkamp, Gerhard Müller-Newen, Martina Crysandt, Stefan Wilop, Edgar Jost, Steffen Koschmieder, Ruth Knüchel, Tim H Brümmendorf, Patrick Ziegler
Intratumoral anti-HuD immunotoxin therapy for small cell lung cancer and neuroblastoma
Debra Ehrlich, Bo Wang, Wei Lu, Peter Dowling, Ruirong Yuan
Homeobox gene expression in acute myeloid leukemia is linked to typical underlying molecular aberrations
Karolina Skvarova Kramarzova, Karel Fiser, Ester Mejstrikova, Katerina Rejlova, Marketa Zaliova, Maarten Fornerod, Harry A Drabkin, Marry M van den Heuvel-Eibrink, Jan Stary, Jan Trka, Julia Starkova
Microrna expression signatures predict patient progression and disease outcome in pediatric embryonal central nervous system neoplasms
Maria Braoudaki, George I Lambrou, Krinio Giannikou, Vasilis Milionis, Kalliopi Stefanaki, Diane K Birks, Neophytos Prodromou, Aggeliki Kolialexi, Antonis Kattamis, Chara A Spiliopoulou, Fotini Tzortzatou-Stathopoulou, Emmanouel Kanavakis
XPO1/CRM1-Selective Inhibitors of Nuclear Export (SINE) reduce tumor spreading and improve overall survival in preclinical models of prostate cancer (PCa)
Giovanni Luca Gravina, Monica Tortoreto, Andrea Mancini, Alessandro Addis, Ernesto Di Cesare, Andrea Lenzi, Yosef Landesman, Dilara McCauley, Michael Kauffman, Sharon Shacham, Nadia Zaffaroni, Claudio Festuccia
A phase II study of dacetuzumab (SGN-40) in patients with relapsed diffuse large B-cell lymphoma (DLBCL) and correlative analyses of patient-specific factors
Sven de Vos, Andres Forero-Torres, Stephen M Ansell, Brad Kahl, Bruce D Cheson, Nancy L Bartlett, Richard R Furman, Jane N Winter, Henry Kaplan, John Timmerman, Nancy C Whiting, Jonathan G Drachman, Ranjana Advani
The Src homology-2 protein Shb modulates focal adhesion kinase signaling in a BCR-ABL myeloproliferative disorder causing accelerated progression of disease
Karin Gustafsson, Maria Jamalpour, Camilla Trinh, Michael G Kharas, Michael Welsh
Identification of a promising PI3K inhibitor for the treatment of multiple myeloma through the structural optimization
Kunkun Han, Xin Xu, Guodong Chen, Yuanying Zeng, Jingyu Zhu, Xiaolin Du, Zubin Zhang, Biyin Cao, Zhaopeng Liu, Xinliang Mao
Romidepsin for the treatment of relapsed/refractory peripheral T-cell lymphoma: pivotal study update demonstrates durable responses
Bertrand Coiffier, Barbara Pro, H Miles Prince, Francine Foss, Lubomir Sokol, Matthew Greenwood, Dolores Caballero, Franck Morschhauser, Martin Wilhelm, Lauren Pinter-Brown, Swaminathan Padmanabhan Iyer, Andrei Shustov, Tina Nielsen, Jean Nichols, Julie Wolfson, Barbara Balser, Steven Horwitz
Host bone marrow-derived IL-12 enhances donor T cell engraftment in a mouse model of bone marrow transplantation
Katarzyna A Darlak, Ying Wang, Jian-Ming Li, Wayne AC Harris, Cynthia R Giver, Chunzi Huang, Edmund K Waller
A phase I study of AST1306, a novel irreversible EGFR and HER2 kinase inhibitor, in patients with advanced solid tumors
Jian Zhang, Junning Cao, Jin Li, Yifan Zhang, Zhiyu Chen, Wei Peng, Si Sun, Naiqing Zhao, Jiachen Wang, Dafang Zhong, Xiaofang Zhang, Jing Zhang
ATP directed agent, 8-chloro-adenosine, induces AMP activated protein kinase activity, leading to autophagic cell death in breast cancer cells
Christine M Stellrecht, Hima V Vangapandu, Xiao-Feng Le, Weiqun Mao, Shujun Shentu
The mutation profile of JAK2 and CALR in Chinese Han patients with Philadelphia chromosome-negative myeloproliferative neoplasms
Zhiyuan Wu, Xinju Zhang, Xiao Xu, Yuming Chen, Tingting Hu, Zhihua Kang, Shibao Li, Hua Wang, Weiwei Liu, Xiaochao Ma, Ming Guan
Tissue factor in tumor microenvironment: a systematic review
Xiao Han, Bo Guo, Yongsheng Li, Bo Zhu