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Zeitschrift

Journal of Hematology & Oncology

Journal of Hematology & Oncology 1/2015

Ausgabe 1/2015

Inhaltsverzeichnis ( 132 Artikel )

01.12.2015 | Research | Ausgabe 1/2015 Open Access

Galectin-3 mediates bone marrow microenvironment-induced drug resistance in acute leukemia cells via Wnt/β-catenin signaling pathway

Kaimin Hu, Yanjun Gu, Lixia Lou, Lizhen Liu, Yongxian Hu, Binsheng Wang, Yi Luo, Jimin Shi, Xiaohong Yu, He Huang

01.12.2015 | Letter to the Editor | Ausgabe 1/2015 Open Access

Evaluation of the anti-tumor effects of lactate dehydrogenase inhibitor galloflavin in endometrial cancer cells

Xiaoyun Han, Xiugui Sheng, Hannah M Jones, Amanda L Jackson, Joshua Kilgore, Jessica E Stine, Monica N Schointuch, Chunxiao Zhou, Victoria L Bae-Jump

01.12.2015 | Research | Ausgabe 1/2015 Open Access

IGF-IR determines the fates of BCR/ABL leukemia

Jingjing Xie, Xiaoli Chen, Junke Zheng, Chunling Li, Satomi Stacy, Martin Holzenberger, Xuemei Hu, Cheng Cheng Zhang

01.12.2015 | Research | Ausgabe 1/2015 Open Access

Non-myeloablative allogeneic hematopoietic cell transplantation following fludarabine plus 2 Gy TBI or ATG plus 8 Gy TLI: a phase II randomized study from the Belgian Hematological Society

Frédéric Baron, Pierre Zachée, Johan Maertens, Tessa Kerre, Aurélie Ory, Laurence Seidel, Carlos Graux, Philippe Lewalle, Michel Van Gelder, Koen Theunissen, Evelyne Willems, Marie-Paule Emonds, Ann De Becker, Yves Beguin

01.12.2015 | Letter to the Editor | Ausgabe 1/2015 Open Access

Persistent molecular remission of refractory acute myeloid leukemia with inv(16)(p13.1q22) in an elderly patient induced by cytarabine ocfosfate hydrate

Masahisa Arahata, Yukihiro Shimizu, Hidesaku Asakura, Shinji Nakao

01.12.2015 | Review | Ausgabe 1/2015 Open Access

MicroRNAs in pediatric central nervous system embryonal neoplasms: the known unknown

Maria Braoudaki, George I Lambrou

01.12.2015 | Letter to the Editor | Ausgabe 1/2015 Open Access

Loss of Angiopoietin-like 7 diminishes the regeneration capacity of hematopoietic stem and progenitor cells

Yiren Xiao, Xinru Wei, Zhiwu Jiang, Xiangmeng Wang, Wei Ye, Xin Liu, Minjie Zhang, Yan Xu, Donghai Wu, Liangxue Lai, Huihui Yao, Zixia Liu, Su Cao, Pentao Liu, Bing Xu, Yangqiu Li, Yao Yao, Duanqing Pei, Peng Li

01.12.2015 | Research | Ausgabe 1/2015 Open Access

Hematology research output from Chinese authors and other countries: a 10-year survey of the literature

Lei Zhang, Xin Ye, Yi Sun, An-mei Deng, Bao-hua Qian

01.12.2015 | Research | Ausgabe 1/2015 Open Access

Notch1 phenotype and clinical stage progression in non-small cell lung cancer

Dat Nguyen, Larry Rubinstein, Naoko Takebe, Lucio Miele, Joseph E Tomaszewski, Percy Ivy, James H Doroshow, Sherry X Yang

01.12.2015 | Research | Ausgabe 1/2015 Open Access

Insulin like growth factor binding protein 7 (IGFBP7) expression is linked to poor prognosis but may protect from bone disease in multiple myeloma

Arnold Bolomsky, Dirk Hose, Martin Schreder, Anja Seckinger, Susanne Lipp, Bernard Klein, Daniel Heintel, Heinz Ludwig, Niklas Zojer

01.12.2015 | Letter to the Editor | Ausgabe 1/2015 Open Access

High expression of neuroguidin increases the sensitivity of acute myeloid leukemia cells to chemotherapeutic drugs

Kejun Chen, Shuqing Lü, Hui Cheng, Gusheng Tang, Min Liu, Hong Zhou, Jianmin Wang

01.12.2015 | Review | Ausgabe 1/2015 Open Access

Role of microRNA in chronic lymphocytic leukemia onset and progression

Veronica Balatti, Yuri Pekarky, Carlo M Croce

01.12.2015 | Research | Ausgabe 1/2015 Open Access

Soluble NKG2D ligand promotes MDSC expansion and skews macrophage to the alternatively activated phenotype

Gang Xiao, Xuanjun Wang, Jun Sheng, Shengjun Lu, Xuezhong Yu, Jennifer D Wu

01.12.2015 | Review | Ausgabe 1/2015 Open Access

Transfer of microRNAs by extracellular membrane microvesicles: a nascent crosstalk model in tumor pathogenesis, especially tumor cell-microenvironment interactions

Li Zhang, C Alexander Valencia, Biao Dong, Meng Chen, Pu-Jun Guan, Ling Pan

01.12.2015 | Research | Ausgabe 1/2015 Open Access

DNA methyltransferase 1 functions through C/ebpa to maintain hematopoietic stem and progenitor cells in zebrafish

Xiaohui Liu, Xiaoe Jia, Hao Yuan, Ke Ma, Yi Chen, Yi Jin, Min Deng, Weijun Pan, Saijuan Chen, Zhu Chen, Hugues de The, Leonard I Zon, Yi Zhou, Jun Zhou, Jun Zhu

01.12.2015 | Review | Ausgabe 1/2015 Open Access

Cancer stem cells in basic science and in translational oncology: can we translate into clinical application?

Axel Schulenburg, Katharina Blatt, Sabine Cerny-Reiterer, Irina Sadovnik, Harald Herrmann, Brigitte Marian, Thomas W Grunt, Christoph C Zielinski, Peter Valent

01.12.2015 | Review | Ausgabe 1/2015 Open Access

Novel ALK inhibitors in clinical use and development

Chaitanya Iragavarapu, Milaim Mustafa, Akintunde Akinleye, Muhammad Furqan, Varun Mittal, Shundong Cang, Delong Liu

01.12.2015 | Research | Ausgabe 1/2015 Open Access

AntiCD3Fv fused to human interleukin-3 deletion variant redirected T cells against human acute myeloid leukemic stem cells

Dongmei Fan, Zhenzhen Li, Xiaolong Zhang, Yuqi Yang, Xiangfei Yuan, Xiuli Zhang, Ming Yang, Yizhi Zhang, Dongsheng Xiong

01.12.2015 | Reviewer acknowledgement | Ausgabe 1/2015 Open Access

Journal of Hematology & Oncology reviewer acknowledgement 2014

Delong Liu, Thalyana Smith-Vikos

01.12.2015 | Review | Ausgabe 1/2015 Open Access

Expression and role of RIP140/NRIP1 in chronic lymphocytic leukemia

Marion Lapierre, Audrey Castet-Nicolas, Delphine Gitenay, Stéphan Jalaguier, Catherine Teyssier, Caroline Bret, Guillaume Cartron, Jérôme Moreaux, Vincent Cavaillès

01.12.2015 | Research | Ausgabe 1/2015 Open Access

Local administration of a novel Toll-like receptor 7 agonist in combination with doxorubicin induces durable tumouricidal effects in a murine model of T cell lymphoma

Jiang Zhu, Shiping He, Jie Du, Zhulin Wang, Wang Li, Xianxiong Chen, Wenqi Jiang, Duo Zheng, Guangyi Jin

01.12.2015 | Research | Ausgabe 1/2015 Open Access

Alpha-enolase promotes cell glycolysis, growth, migration, and invasion in non-small cell lung cancer through FAK-mediated PI3K/AKT pathway

Qiao-Fen Fu, Yan Liu, Yue Fan, Sheng-Ni Hua, Hong-Ying Qu, Su-Wei Dong, Rui-Lei Li, Meng-Yang Zhao, Yan Zhen, Xiao-Li Yu, Yi-Yu Chen, Rong-Cheng Luo, Rong Li, Li-Bo Li, Xiao-Jie Deng, Wei-Yi Fang, Zhen Liu, Xin Song

01.12.2015 | Research | Ausgabe 1/2015 Open Access

Coexpression of gene Oct4 and Nanog initiates stem cell characteristics in hepatocellular carcinoma and promotes epithelial-mesenchymal transition through activation of Stat3/Snail signaling

Xin Yin, Bo-Heng Zhang, Su-Su Zheng, Dong-Mei Gao, Shuang-Jian Qiu, Wei-Zhong Wu, Zheng-Gang Ren

01.12.2015 | Research | Ausgabe 1/2015 Open Access

Trogocytic intercellular membrane exchanges among hematological tumors

Joel LeMaoult, Julien Caumartin, Marina Daouya, Magdalena Switala, Vera Rebmann, Bertrand Arnulf, Edgardo D Carosella

01.12.2015 | Letter to the Editor | Ausgabe 1/2015 Open Access

VSTM-v1, a potential myeloid differentiation antigen that is downregulated in bone marrow cells from myeloid leukemia patients

Min Xie, Ting Li, Ning Li, Jinlan Li, Qiumei Yao, Wenling Han, Guorui Ruan

01.12.2015 | Research | Ausgabe 1/2015 Open Access

Aloperine executes antitumor effects against multiple myeloma through dual apoptotic mechanisms

He Wang, Shu Yang, Hong Zhou, Mingna Sun, Lingran Du, Minyan Wei, Meixia Luo, Jingzhu Huang, Hongzhu Deng, Yinghong Feng, Jun Huang, Yi Zhou

01.12.2015 | Editorial | Ausgabe 1/2015 Open Access

Pass quantity, focus on quality

Delong Liu, Weijing Sun, Jingzhou Hou, Ruirong Yuan, Zihai Li

01.12.2015 | Research | Ausgabe 1/2015 Open Access

EVI1 promotes tumor growth via transcriptional repression of MS4A3

Gerwin Heller, Anna Rommer, Katarina Steinleitner, Julia Etzler, Hubert Hackl, Petra Heffeter, Erwin Tomasich, Martin Filipits, Birgit Steinmetz, Thais Topakian, Simone Klingenbrunner, Barbara Ziegler, Andreas Spittler, Sabine Zöchbauer-Müller, Walter Berger, Rotraud Wieser

01.12.2015 | Review | Ausgabe 1/2015 Open Access

Zebrafish as a model for leukemia and other hematopoietic disorders

Parisa Rasighaemi, Faiza Basheer, Clifford Liongue, Alister C Ward

01.12.2015 | Review | Ausgabe 1/2015 Open Access

Competing endogenous RNA networks: tying the essential knots for cancer biology and therapeutics

Avencia Sanchez-Mejias, Yvonne Tay

01.12.2015 | Review | Ausgabe 1/2015 Open Access

RNA-guided CRISPR-Cas technologies for genome-scale investigation of disease processes

Sean E Humphrey, Andrea L Kasinski

01.12.2015 | Research | Ausgabe 1/2015 Open Access

Chromosomal rearrangement involving 11q23 locus in chronic myelogenous leukemia: a rare phenomenon frequently associated with disease progression and poor prognosis

Wei Wang, Guilin Tang, Jorge E Cortes, Hui Liu, Di Ai, C Cameron Yin, Shaoying Li, Joseph D Khoury, Carlos Bueso-Ramos, L Jeffrey Medeiros, Shimin Hu

01.12.2015 | Review | Ausgabe 1/2015 Open Access

Endothelial progenitor cells in ischemic stroke: an exploration from hypothesis to therapy

Ya-Feng Li, Li-Na Ren, Geng Guo, Lee Anne Cannella, Valeria Chernaya, Sonia Samuel, Su-Xuan Liu, Hong Wang, Xiao-Feng Yang

01.12.2015 | Letter to the Editor | Ausgabe 1/2015 Open Access

Alteration of gene expression profile following PPP2R5C knockdown may be associated with proliferation suppression and increased apoptosis of K562 cells

Sichu Liu, Qi Shen, Yu Chen, Chengwu Zeng, Changshu Cao, Lijian Yang, Shaohua Chen, Xiuli Wu, Bo Li, Yangqiu Li

01.12.2015 | Research | Ausgabe 1/2015 Open Access

A novel vaccine for mantle cell lymphoma based on targeting cyclin D1 to dendritic cells via CD40

Jingtao Chen, Gerard Zurawski, Sandy Zurawski, Zhiqing Wang, Keiko Akagawa, Sangkon Oh, Ueno Hideki, Joseph Fay, Jacques Banchereau, Wenru Song, A Karolina Palucka

01.12.2015 | Letter to the Editor | Ausgabe 1/2015 Open Access

TIM-3/Gal-9 interaction induces IFNγ-dependent IDO1 expression in acute myeloid leukemia blast cells

Valentina Folgiero, Loredana Cifaldi, Giuseppina Li Pira, Bianca Maria Goffredo, Luciana Vinti, Franco Locatelli

01.12.2015 | Research | Ausgabe 1/2015 Open Access

The non-peptide thrombopoietin receptor agonist eltrombopag stimulates megakaryopoiesis in bone marrow cells from patients with relapsed multiple myeloma

Jee-Yeong Jeong, Michelle S Levine, Nirmalee Abayasekara, Nancy Berliner, Jacob Laubach, Gary J Vanasse

01.12.2015 | Review | Ausgabe 1/2015 Open Access

piRNA involvement in genome stability and human cancer

Miguel Moyano, Giovanni Stefani

01.12.2015 | Research | Ausgabe 1/2015 Open Access

YM155 potently kills acute lymphoblastic leukemia cells through activation of the DNA damage pathway

Bill H Chang, Kara Johnson, Dorian LaTocha, Joelle S J Rowley, Jade Bryant, Russell Burke, Rebecca L Smith, Marc Loriaux, Markus Müschen, Charles Mullighan, Brian J Druker, Jeffrey W Tyner

01.12.2015 | Letter to the Editor | Ausgabe 1/2015 Open Access

Heat shock factor 1 is a potent therapeutic target for enhancing the efficacy of treatments for multiple myeloma with adverse prognosis

Sophie Bustany, Julie Cahu, Géraldine Descamps, Catherine Pellat-Deceunynck, Brigitte Sola

01.12.2015 | Research | Ausgabe 1/2015 Open Access

Oroxylin A promotes PTEN-mediated negative regulation of MDM2 transcription via SIRT3-mediated deacetylation to stabilize p53 and inhibit glycolysis in wt-p53 cancer cells

Kai Zhao, Yuxin Zhou, Chen Qiao, Ting Ni, Zhiyu Li, Xiaotang Wang, Qinglong Guo, Na Lu, Libin Wei

01.12.2015 | Research | Ausgabe 1/2015 Open Access

Deep sequencing and SNP array analyses of pediatric T-cell acute lymphoblastic leukemia reveal NOTCH1 mutations in minor subclones and a high incidence of uniparental isodisomies affecting CDKN2A

Kristina Karrman, Anders Castor, Mikael Behrendtz, Erik Forestier, Linda Olsson, Mats Ehinger, Andrea Biloglav, Thoas Fioretos, Kajsa Paulsson, Bertil Johansson

01.12.2015 | Research | Ausgabe 1/2015 Open Access

The long non-coding RNA, GAS5, enhances gefitinib-induced cell death in innate EGFR tyrosine kinase inhibitor-resistant lung adenocarcinoma cells with wide-type EGFR via downregulation of the IGF-1R expression

Siyuan Dong, Xiaohan Qu, Wenya Li, Xinwen Zhong, Peiwen Li, Shize Yang, Xitao Chen, Mingrui Shao, Lin Zhang

01.12.2015 | Review | Ausgabe 1/2015 Open Access

Novel approaches in the management of pancreatic ductal adenocarcinoma: potential promises for the future

Gaurav Goel, Weijing Sun

01.12.2015 | Research article | Ausgabe 1/2015 Open Access

TP53 mutation characteristics in therapy-related myelodysplastic syndromes and acute myeloid leukemia is similar to de novo diseases

Chi Young Ok, Keyur P Patel, Guillermo Garcia-Manero, Mark J Routbort, Jie Peng, Guilin Tang, Maitrayee Goswami, Ken H Young, Rajesh Singh, L Jeffrey Medeiros, Hagop M Kantarjian, Rajyalakshmi Luthra, Sa A Wang

01.12.2015 | Research article | Ausgabe 1/2015 Open Access

Azacytidine sensitizes acute myeloid leukemia cells to arsenic trioxide by up-regulating the arsenic transporter aquaglyceroporin 9

David Chau, Karen Ng, Thomas Sau-Yan Chan, Yuen-Yee Cheng, Bonnie Fong, Sidney Tam, Yok-Lam Kwong, Eric Tse

01.12.2015 | Review | Ausgabe 1/2015 Open Access

F-BAR family proteins, emerging regulators for cell membrane dynamic changes—from structure to human diseases

Suxuan Liu, Xinyu Xiong, Xianxian Zhao, Xiaofeng Yang, Hong Wang

01.12.2015 | Research article | Ausgabe 1/2015 Open Access

Clinical significance of day 5 peripheral blast clearance rate in the evaluation of early treatment response and prognosis of patients with acute myeloid leukemia

Cong Yu, Qing-lei Kong, Yun-xiang Zhang, Xiang-qin Weng, Jing Wu, Yan Sheng, Chun-lei Jiang, Yong-mei Zhu, Qi Cao, Shu-min Xiong, Jun-min Li, Xiao-dong Xi, Sai-juan Chen, Bing Chen

01.12.2015 | Rapid Communication | Ausgabe 1/2015 Open Access

The serum CXCL13 level is associated with the Glasgow Prognostic Score in extranodal NK/T-cell lymphoma patients

Seok Jin Kim, Kyung Ju Ryu, Mineui Hong, Young Hyeh Ko, Won Seog Kim

01.12.2015 | Research article | Ausgabe 1/2015 Open Access

Long non-coding RNA ANRIL is upregulated in hepatocellular carcinoma and regulates cell apoptosis by epigenetic silencing of KLF2

Ming-de Huang, Wen-ming Chen, Fu-zhen Qi, Rui Xia, Ming Sun, Tong-peng Xu, Li Yin, Er-bao Zhang, Wei De, Yong-qian Shu

01.12.2015 | Case report | Ausgabe 1/2015 Open Access

Improved disease markers suggest dual response in a patient with metastatic castration resistant prostate cancer and chronic lymphocytic leukemia following active cellular immunotherapy

Heather H. Cheng, Colleen Soleau, Evan Y. Yu

01.12.2015 | Letter to the Editor | Ausgabe 1/2015 Open Access

The impact of taxane-based preoperative chemotherapy in gastroesophageal signet ring cell adenocarcinomas

Stefano Kim, Frederic Fiteni, Sophie Paget-Bailly, François Ghiringhelli, Zaher Lakkis, Marine Jary, Francine Fein, Franck Bonnetain, Christophe Mariette, Christophe Borg

01.12.2015 | Research Article | Ausgabe 1/2015 Open Access

Role of gonadotropin-releasing hormone analogues in metastatic male breast cancer: results from a pooled analysis

Luigi Di Lauro, Laura Pizzuti, Maddalena Barba, Domenico Sergi, Isabella Sperduti, Marcella Mottolese, Carla Azzurra Amoreo, Franca Belli, Patrizia Vici, Valerie Speirs, Daniele Santini, Ruggero De Maria, Marcello Maugeri-Saccà

01.12.2015 | Short Report | Ausgabe 1/2015 Open Access

Phase II study of biomarker-guided neoadjuvant treatment strategy for IIIA-N2 non-small cell lung cancer based on epidermal growth factor receptor mutation status

Wenzhao Zhong, Xuening Yang, Honghong Yan, Xuchao Zhang, Jian Su, Zhihong Chen, Riqiang Liao, Qiang Nie, Song Dong, Qing Zhou, Jinji Yang, Haiyan Tu, Yi-Long Wu

01.12.2015 | Short Report | Ausgabe 1/2015 Open Access

Mutation analysis of Chinese sporadic congenital sideroblastic anemia by targeted capture sequencing

Wenbin An, Jingliao Zhang, Lixian Chang, Yingchi Zhang, Yang Wan, Yuanyuan Ren, Deyun Niu, Jian Wu, Xiaofan Zhu, Ye Guo

01.12.2015 | Research Article | Ausgabe 1/2015 Open Access

microRNA-26a suppresses recruitment of macrophages by down-regulating macrophage colony-stimulating factor expression through the PI3K/Akt pathway in hepatocellular carcinoma

Zong-Tao Chai, Xiao-Dong Zhu, Jian-Yang Ao, Wen-Quan Wang, Dong-Mei Gao, Jian Kong, Ning Zhang, Yuan-Yuan Zhang, Bo-Gen Ye, De-Ning Ma, Hao Cai, Hui-Chuan Sun

01.12.2015 | Research Article | Ausgabe 1/2015 Open Access

Long non-coding RNA ANRIL is upregulated in hepatocellular carcinoma and regulates cell proliferation by epigenetic silencing of KLF2

Ming-de Huang, Wen-ming Chen, Fu-zhen Qi, Rui Xia, Ming Sun, Tong-peng Xu, Li Yin, Er-bao Zhang, Wei De, Yong-qian Shu

01.12.2015 | Research Article | Ausgabe 1/2015 Open Access

HER2/neu-directed therapy for biliary tract cancer

Milind Javle, Chaitanya Churi, HyunSeon C. Kang, Rachna Shroff, Filip Janku, Rakesh Surapaneni, Mingxin Zuo, Christian Barrera, Humaid Alshamsi, Sunil Krishnan, Lopa Mishra, Robert A. Wolff, Ahmed O. Kaseb, Melanie B. Thomas, Abby B. Siegel

01.12.2015 | Research | Ausgabe 1/2015 Open Access

Quantitative evaluation of the immunodeficiency of a mouse strain by tumor engraftments

Wei Ye, Zhiwu Jiang, Guan-Xiong Li, Yiren Xiao, Simiao Lin, Yunxin Lai, Suna Wang, Baiheng Li, Bei Jia, Yin Li, Zhi-liang Huang, Jin Li, Fenglan Feng, Shuhua Li, Huihui Yao, Zixia Liu, Su Cao, Lin Xu, Yangqiu Li, Donghai Wu, Lingwen Zeng, Mei Zhong, Pentao Liu, Zhe-sheng Wen, Bing Xu, Yao Yao, Duanqing Pei, Peng Li

01.12.2015 | Review | Ausgabe 1/2015 Open Access

Targeting neoplastic B cells and harnessing microenvironment: the “double face” of ibrutinib and idelalisib

Rossana Maffei, Stefania Fiorcari, Silvia Martinelli, Leonardo Potenza, Mario Luppi, Roberto Marasca

01.12.2015 | Research Article | Ausgabe 1/2015 Open Access

Methotrexate resistance in relation to treatment outcome in childhood acute lymphoblastic leukemia

Anna Wojtuszkiewicz, Godefridus J. Peters, Nicole L. van Woerden, Boas Dubbelman, Gabriele Escherich, Kjeld Schmiegelow, Edwin Sonneveld, Rob Pieters, Peter M. van de Ven, Gerrit Jansen, Yehuda G. Assaraf, Gertjan J. L. Kaspers, Jacqueline Cloos

01.12.2015 | Research Article | Ausgabe 1/2015 Open Access

Evaluation of targeting c-Src by the RGT-containing peptide as a novel antithrombotic strategy

Jiansong Huang, Xiaofeng Shi, Wenda Xi, Ping Liu, Zhangbiao Long, Xiaodong Xi

01.12.2015 | Research Article | Ausgabe 1/2015 Open Access

Targeting Wnt pathway in mantle cell lymphoma-initiating cells

Rohit Mathur, Lalit Sehgal, Frank K. Braun, Zuzana Berkova, Jorge Romaguerra, Michael Wang, M. Alma Rodriguez, Luis Fayad, Sattva S. Neelapu, Felipe Samaniego

01.12.2015 | Research | Ausgabe 1/2015 Open Access

Angptl4 is upregulated under inflammatory conditions in the bone marrow of mice, expands myeloid progenitors, and accelerates reconstitution of platelets after myelosuppressive therapy

Anne Schumacher, Bernd Denecke, Till Braunschweig, Jasmin Stahlschmidt, Susanne Ziegler, Lars-Ove Brandenburg, Matthias B. Stope, Antons Martincuks, Michael Vogt, Dieter Görtz, Annalisa Camporeale, Valeria Poli, Gerhard Müller-Newen, Tim H. Brümmendorf, Patrick Ziegler

01.12.2015 | Research article | Ausgabe 1/2015 Open Access

Stage, age, and EBV status impact outcomes of plasmablastic lymphoma patients: a clinicopathologic analysis of 61 patients

Sanam Loghavi, Khaled Alayed, Tariq N. Aladily, Zhuang Zuo, Siok-Bian Ng, Guilin Tang, Shimin Hu, C. Cameron Yin, Roberto N. Miranda, L. Jeffrey Medeiros, Joseph D. Khoury

01.12.2015 | RESEARCH ARTICLE | Ausgabe 1/2015 Open Access

STUMP un“stumped”: anti-tumor response to anaplastic lymphoma kinase (ALK) inhibitor based targeted therapy in uterine inflammatory myofibroblastic tumor with myxoid features harboring DCTN1-ALK fusion

Vivek Subbiah, Caitlin McMahon, Shreyaskumar Patel, Ralph Zinner, Elvio G Silva, Julia A. Elvin, Ishwaria M. Subbiah, Chimela Ohaji, Dhakshina Moorthy Ganeshan, Deepa Anand, Charles F. Levenback, Jenny Berry, Tim Brennan, Juliann Chmielecki, Zachary R. Chalmers, John Mayfield, Vincent A. Miller, Philip J. Stephens, Jeffrey S. Ross, Siraj M. Ali

01.12.2015 | Research Article | Ausgabe 1/2015 Open Access

Knockdown of SUMO-activating enzyme subunit 2 (SAE2) suppresses cancer malignancy and enhances chemotherapy sensitivity in small cell lung cancer

Xiaoke Liu, Yong Xu, Zongguo Pang, Fuchun Guo, Qing Qin, Tao Yin, Yaxiong Sang, Chengjun Feng, Xiaoyu Li, Li Jiang, Pei Shu, Yongsheng Wang

01.12.2015 | Review | Ausgabe 1/2015 Open Access

MiRNA-based therapeutic intervention of cancer

Srivatsava Naidu, Peter Magee, Michela Garofalo

01.12.2015 | Letter to the Editor | Ausgabe 1/2015 Open Access

Identification of the NUP98-PHF23 fusion gene in pediatric cytogenetically normal acute myeloid leukemia by whole-transcriptome sequencing

Marco Togni, Riccardo Masetti, Martina Pigazzi, Annalisa Astolfi, Daniele Zama, Valentina Indio, Salvatore Serravalle, Elena Manara, Valeria Bisio, Carmelo Rizzari, Giuseppe Basso, Andrea Pession, Franco Locatelli

01.12.2015 | Research Article | Ausgabe 1/2015 Open Access

Multiparameter analysis of homogeneously R-CHOP-treated diffuse large B cell lymphomas identifies CD5 and FOXP1 as relevant prognostic biomarkers: report of the prospective SAKK 38/07 study

Alexandar Tzankov, Nora Leu, Simone Muenst, Darius Juskevicius, Dirk Klingbiel, Christoph Mamot, Stephan Dirnhofer

01.12.2015 | Research Article | Ausgabe 1/2015 Open Access

Particulate cytoplasmic structures with high concentration of ubiquitin-proteasome accumulate in myeloid neoplasms

Alessandro Pecci, Vittorio Necchi, Serena Barozzi, Agostina Vitali, Emanuela Boveri, Chiara Elena, Paolo Bernasconi, Patrizia Noris, Enrico Solcia

01.12.2015 | Letter to the Editor | Ausgabe 1/2015 Open Access

Upregulated TCRζ improves cytokine secretion in T cells from patients with AML

Shaohua Chen, Xianfeng Zha, Li Shi, Lingling Zhou, Lijian Yang, Bo Li, Xiuli Wu, Jun Zhong, Tao Zhang, Yuhong Lu, Kanger Zhu, Yangqiu Li

01.12.2015 | Letter to the Editor | Ausgabe 1/2015 Open Access

Mutations in the D1 domain of von Willebrand factor impair their propeptide-dependent multimerization, intracellular trafficking and secretion

Jie Yin, Zhenni Ma, Jian Su, Jiong-Wei Wang, Xiaojuan Zhao, Jing Ling, Xia Bai, Wanyan Ouyang, Zhaoyue Wang, Ziqiang Yu, Changgeng Ruan

01.12.2015 | Research Article | Ausgabe 1/2015 Open Access

Waldenström macroglobulinemia with extramedullary involvement at initial diagnosis portends a poorer prognosis

Xin Cao, Qing Ye, Robert Z. Orlowski, Xiaoxiao Wang, Sanam Loghavi, Meifeng Tu, Sheeba K. Thomas, Jatin Shan, Shaoying Li, Muzaffar Qazilbash, C. Cameron Yin, Donna Weber, Roberto N. Miranda, Zijun Y. Xu-Monette, L. Jeffrey Medeiros, Ken H. Young

01.12.2015 | Review | Ausgabe 1/2015 Open Access

Sampling circulating tumor cells for clinical benefits: how frequent?

Sai Mun Leong, Karen ML Tan, Hui Wen Chua, Doreen Tan, Delly Fareda, Saabry Osmany, Mo-Huang Li, Steven Tucker, Evelyn SC Koay

01.12.2015 | Letter to the Editor | Ausgabe 1/2015 Open Access

Evaluation of hGM-CSF/hTNFα surface-modified prostate cancer therapeutic vaccine in the huPBL-SCID chimeric mouse model

Shouhua Lai, Zhiyong Huang, Yunting Guo, Yunqin Cui, Lei Wang, Weifeng Ren, Furong Ying, Hui Gao, Lingxia He, Tieli Zhou, Jiegen Jiang, Jimin Gao

01.12.2015 | Research Article | Ausgabe 1/2015 Open Access

High expression of endoplasmic reticulum chaperone grp94 is a novel molecular hallmark of malignant plasma cells in multiple myeloma

Saurabh Chhabra, Sandeep Jain, Caroline Wallace, Feng Hong, Bei Liu

01.12.2015 | Case report | Ausgabe 1/2015 Open Access

Conditioning with rabbit versus horse ATG dramatically alters clinical outcomes in identical twins with severe aplastic anemia transplanted with the same allogeneic donor

P. T. Vo, J. Pantin, C. Ramos, L. Cook, E. Cho, R. Kurlander, H. Khuu, J. Barrett, S. Leitman, R. W. Childs

01.12.2015 | Letter to the Editor | Ausgabe 1/2015 Open Access

Platelet functional alterations in a Bernard-Soulier syndrome patient with filamin A mutation

Jiaming Li, KeSheng Dai, Zhaoyue Wang, Lijuan Cao, Xia Bai, Changgeng Ruan

01.12.2015 | Research Article | Ausgabe 1/2015 Open Access

Infused autograft lymphocyte-to-monocyte ratio and survival in T-cell lymphoma post-autologous peripheral blood hematopoietic stem cell transplantation

Luis F. Porrata, David J. Inwards, Stephen M. Ansell, Ivana N. Micallef, Patrick B. Johnston, William J. Hogan, Svetomir N. Markovic

01.12.2015 | Research Article | Ausgabe 1/2015 Open Access

In vitro and in vivo identification of ABCB1 as an efflux transporter of bosutinib

Sara Redaelli, Pietro Perini, Monica Ceccon, Rocco Piazza, Roberta Rigolio, Mario Mauri, Frank Boschelli, Athina Giannoudis, Carlo Gambacorti-Passerini

01.12.2015 | Research Article | Ausgabe 1/2015 Open Access

The synergic effect of vincristine and vorinostat in leukemia in vitro and in vivo

Min-Wu Chao, Mei-Jung Lai, Jing-Ping Liou, Ya-Ling Chang, Jing-Chi Wang, Shiow-Lin Pan, Che-Ming Teng

01.12.2015 | Review | Ausgabe 1/2015 Open Access

Exosomes in cancer: small particle, big player

Xu Zhang, Xiao Yuan, Hui Shi, Lijun Wu, Hui Qian, Wenrong Xu

01.12.2015 | Research article | Ausgabe 1/2015 Open Access

Donor-specific anti-human leukocyte antigen antibodies were associated with primary graft failure after unmanipulated haploidentical blood and marrow transplantation: a prospective study with randomly assigned training and validation sets

Ying-Jun Chang, Xiang-Yu Zhao, Lan-Ping Xu, Xiao-Hui Zhang, Yu Wang, Wei Han, Huan Chen, Feng-Rong Wang, Xiao-Dong Mo, Yuan-Yuan Zhang, Ming-Rui Huo, Xiao-Su Zhao, Kong Y, Kai-Yan Liu, Xiao-Jun Huang

01.12.2015 | Review | Ausgabe 1/2015 Open Access

Therapeutic potential of new B cell-targeted agents in the treatment of elderly and unfit patients with chronic lymphocytic leukemia

Kanti R. Rai

01.12.2015 | Review | Ausgabe 1/2015 Open Access

Advances in the management of gastrointestinal cancers—an upcoming role of immune checkpoint blockade

Gaurav Goel, Weijing Sun

01.12.2015 | Review | Ausgabe 1/2015 Open Access

Drugging the unfolded protein response in acute leukemias

Behzad Kharabi Masouleh, Eric Chevet, Jens Panse, Edgar Jost, Michael O’Dwyer, Tim H. Bruemmendorf, Afshin Samali

01.12.2015 | Review | Ausgabe 1/2015 Open Access

Role of DNA methylation in renal cell carcinoma

Niraj Shenoy, Nishanth Vallumsetla, Yiyu Zou, Jose Nahun Galeas, Makardhwaj Shrivastava, Caroline Hu, Katalin Susztak, Amit Verma

01.12.2015 | Research Article | Ausgabe 1/2015 Open Access

TMEM140 is associated with the prognosis of glioma by promoting cell viability and invasion

Bin Li, Ming-Zhu Huang, Xiao-Qiang Wang, Bang-Bao Tao, Jun Zhong, Xu-Hui Wang, Wen-Chuan Zhang, Shi-Ting Li

01.12.2015 | Research Article | Ausgabe 1/2015 Open Access

Favorable outcome of haploidentical hematopoietic stem cell transplantation in Philadelphia chromosome-positive acute lymphoblastic leukemia: a multicenter study in Southwest China

Li Gao, Cheng Zhang, Lei Gao, Yao Liu, Yi Su, Sanbin Wang, Bin Li, Tonghua Yang, Zhong Yuan, Xi Zhang

01.12.2015 | Research Highlight | Ausgabe 1/2015 Open Access

JAK kinase inhibitors for the treatment of acute lymphoblastic leukemia

Sandrine Degryse, Jan Cools

01.12.2015 | Research Highlight | Ausgabe 1/2015 Open Access

Ramucirumab, another anti-angiogenic agent for metastatic colorectal cancer in second-line setting—its impact on clinical practice

Gaurav Goel, Weijing Sun

01.12.2015 | Research Article | Ausgabe 1/2015 Open Access

T cells are functionally not impaired in AML: increased PD-1 expression is only seen at time of relapse and correlates with a shift towards the memory T cell compartment

Frauke M. Schnorfeil, Felix S. Lichtenegger, Katharina Emmerig, Miriam Schlueter, Julia S. Neitz, Rika Draenert, Wolfgang Hiddemann, Marion Subklewe

01.12.2015 | Letter to the Editor | Ausgabe 1/2015 Open Access

Haploinsufficiency of Bcl11b suppresses the progression of ATM-deficient T cell lymphomas

Kerice A. Pinkney, Wenxia Jiang, Brian J. Lee, Denis G. Loredan, Chen Li, Govind Bhagat, Shan Zha

01.12.2015 | Review | Ausgabe 1/2015 Open Access

Non-invasive approaches to monitor EGFR-TKI treatment in non-small-cell lung cancer

Wei Sun, Xun Yuan, Yijun Tian, Hua Wu, Hanxiao Xu, Guoqing Hu, Kongming Wu

01.12.2015 | Research Highlight | Ausgabe 1/2015 Open Access

AFM13: a first-in-class tetravalent bispecific anti-CD30/CD16A antibody for NK cell-mediated immunotherapy

Jingjing Wu, Jiaping Fu, Mingzhi Zhang, Delong Liu

01.12.2015 | Letter to the Editor | Ausgabe 1/2015 Open Access

Anti-leukemic activity of axitinib against cells harboring the BCR-ABL T315I point mutation

Seiichi Okabe, Tetsuzo Tauchi, Yuko Tanaka, Juri Sakuta, Kazuma Ohyashiki

01.12.2015 | Research highlight | Ausgabe 1/2015 Open Access

Palbociclib: a first-in-class CDK4/CDK6 inhibitor for the treatment of hormone-receptor positive advanced breast cancer

Janice Lu

01.12.2015 | Research | Ausgabe 1/2015 Open Access

Genetically modified "obligate" anaerobic Salmonella typhimurium as a therapeutic strategy for neuroblastoma

Zhu-Ling Guo, Bin Yu, Bo-Tao Ning, Shing Chan, Qiu-Bin Lin, James Chun-Bong Li, Jian-Dong Huang, Godfrey Chi-Fung Chan

01.12.2015 | Letter to the Editor | Ausgabe 1/2015 Open Access

Establishment and genetic characterization of a novel mixed-phenotype acute leukemia cell line with EP300-ZNF384 fusion

Nana Ping, Huiying Qiu, Qian Wang, Haiping Dai, Changgeng Ruan, Stefan Ehrentraut, Hans G. Drexler, Roderick A. F. MacLeod, Suning Chen

01.12.2015 | Erratum | Ausgabe 1/2015 Open Access

Erratum: TMEM140 is associated with the prognosis of glioma by promoting cell viability and invasion

Bin Li, Ming-Zhu Huang, Xiao-Qiang Wang, Bang-Bao Tao, Jun Zhong, Xu-Hui Wang, Wen-Chuan Zhang, Shi-Ting Li

01.12.2015 | Rapid Communication | Ausgabe 1/2015 Open Access

Clinical significance of high-dose cytarabine added to cyclophosphamide/total-body irradiation in bone marrow or peripheral blood stem cell transplantation for myeloid malignancy

Yasuyuki Arai, Kazunari Aoki, June Takeda, Tadakazu Kondo, Tetsuya Eto, Shuichi Ota, Hisako Hashimoto, Takahiro Fukuda, Yukiyasu Ozawa, Yoshinobu Kanda, Chiaki Kato, Mineo Kurokawa, Koji Iwato, Makoto Onizuka, Tatsuo Ichinohe, Yoshiko Atsuta, Akiyoshi Takami, on behalf of the AML and MDS Working Group of the Japan Society for Hematopoietic Cell Transplantation

01.12.2015 | Research Article | Ausgabe 1/2015 Open Access

Pharmacokinetics and safety of ixazomib plus lenalidomide–dexamethasone in Asian patients with relapsed/refractory myeloma: a phase 1 study

Neeraj Gupta, Yeow Tee Goh, Chang-Ki Min, Jae Hoon Lee, Kihyun Kim, Raymond S. M. Wong, Chor Sang Chim, Michael J. Hanley, Huyuan Yang, Karthik Venkatakrishnan, Ai-Min Hui, Dixie-Lee Esseltine, Wee Joo Chng

01.12.2015 | Review | Ausgabe 1/2015 Open Access

Blinatumomab: a bispecific T cell engager (BiTE) antibody against CD19/CD3 for refractory acute lymphoid leukemia

Jingjing Wu, Jiaping Fu, Mingzhi Zhang, Delong Liu

01.12.2015 | Rapid Communication | Ausgabe 1/2015 Open Access

Effects of altered ephrin-A5 and EphA4/EphA7 expression on tumor growth in a medulloblastoma mouse model

Shilpa Bhatia, Kellen Hirsch, Nimrah A. Baig, Olga Rodriguez, Olga Timofeeva, Kevin Kavanagh, Yi Chien Lee, Xiao-Jing Wang, Christopher Albanese, Sana D. Karam

01.12.2015 | Research | Ausgabe 1/2015 Open Access

PTTG1 expression is associated with hyperproliferative disease and poor prognosis in multiple myeloma

Jacqueline E. Noll, Kate Vandyke, Duncan R. Hewett, Krzysztof M. Mrozik, Rachel J. Bala, Sharon A. Williams, Chung H. Kok, Andrew CW Zannettino

01.12.2015 | Research | Ausgabe 1/2015 Open Access

Unrelated cord blood transplantation for adult patients with acute myeloid leukemia: higher incidence of acute graft-versus-host disease and lower survival in male patients transplanted with female unrelated cord blood—a report from Eurocord, the Acute Leukemia Working Party, and the Cord Blood Committee of the Cellular Therapy and Immunobiology Working Party of the European Group for Blood and Marrow Transplantation

Frédéric Baron, Myriam Labopin, Annalisa Ruggeri, Mohamad Mohty, Guillermo Sanz, Noel Milpied, Andrea Bacigalupo, Alessandro Rambaldi, Francesca Bonifazi, Alberto Bosi, Jorge Sierra, Ibrahim Yakoub-Agha, Josep Maria Ribera Santasusana, Eliane Gluckman, Arnon Nagler

01.12.2015 | Research | Ausgabe 1/2015 Open Access

Redirection of CD4+ and CD8+ T lymphocytes via an anti-CD3 × anti-CD19 bi-specific antibody combined with cytosine arabinoside and the efficient lysis of patient-derived B-ALL cells

Dongmei Fan, Wei Li, Yuqi Yang, Xiaolong Zhang, Qing Zhang, Yan Yan, Ming Yang, Jianxiang Wang, Dongsheng Xiong

01.12.2015 | Case report | Ausgabe 1/2015 Open Access

Comprehensive serial molecular profiling of an “N of 1” exceptional non-responder with metastatic prostate cancer progressing to small cell carcinoma on treatment

Kunal C. Kadakia, Scott A. Tomlins, Saagar K. Sanghvi, Andi K. Cani, Kei Omata, Daniel H. Hovelson, Chia-Jen Liu, Kathleen A. Cooney

01.12.2015 | Rapid communication | Ausgabe 1/2015 Open Access

All-trans retinoic acid arrests cell cycle in leukemic bone marrow stromal cells by increasing intercellular communication through connexin 43-mediated gap junction

Yao Liu, Qin Wen, Xue-lian Chen, Shi-jie Yang, Lei Gao, Li Gao, Cheng Zhang, Jia-li Li, Xi-xi Xiang, Kai Wan, Xing-hua Chen, Xi Zhang, Jiang-fan Zhong

01.12.2015 | Case report | Ausgabe 1/2015 Open Access

Increase of PD-L1 expressing B-precursor ALL cells in a patient resistant to the CD19/CD3-bispecific T cell engager antibody blinatumomab

Thomas Köhnke, Christina Krupka, Johanna Tischer, Thomas Knösel, Marion Subklewe

01.12.2015 | Erratum | Ausgabe 1/2015 Open Access

Erratum to: The serum CXCL13 level is associated with the Glasgow Prognostic Score in extranodal NK/T-cell lymphoma patients

Seok Jin Kim, Kyung Ju Ryu, Mineui Hong, Young Hyeh Ko, Won Seog Kim

01.12.2015 | Review | Ausgabe 1/2015 Open Access

The roles of stem cell memory T cells in hematological malignancies

Ling Xu, Yikai Zhang, Gengxin Luo, Yangqiu Li

01.12.2015 | Research | Ausgabe 1/2015 Open Access

The Hedgehog pathway as targetable vulnerability with 5-azacytidine in myelodysplastic syndrome and acute myeloid leukemia

Raoul Tibes, Aref Al-Kali, Gavin R Oliver, Devora H Delman, Nanna Hansen, Keerthi Bhagavatula, Jayaram Mohan, Fariborz Rakhshan, Thomas Wood, James M. Foran, Ruben A. Mesa, James M. Bogenberger

01.12.2015 | Research | Ausgabe 1/2015 Open Access

High expression of myocyte enhancer factor 2C (MEF2C) is associated with adverse-risk features and poor outcome in pediatric acute myeloid leukemia: a report from the Children’s Oncology Group

George S. Laszlo, Todd A. Alonzo, Chelsea J. Gudgeon, Kimberly H. Harrington, Alex Kentsis, Robert B. Gerbing, Yi-Cheng Wang, Rhonda E. Ries, Susana C. Raimondi, Betsy A. Hirsch, Alan S. Gamis, Soheil Meshinchi, Roland B. Walter

01.12.2015 | Research | Ausgabe 1/2015 Open Access

Desialylation is associated with apoptosis and phagocytosis of platelets in patients with prolonged isolated thrombocytopenia after allo-HSCT

Xiao-Hui Zhang, Qian-Ming Wang, Jia-Min Zhang, Fei-Er Feng, Feng-Rong Wang, Huan Chen, Yuan-Yuan Zhang, Yu-Hong Chen, Wei Han, Lan-Ping Xu, Kai-Yan Liu, Xiao-Jun Huang

01.12.2015 | Research | Ausgabe 1/2015 Open Access

Small PARP inhibitor PJ-34 induces cell cycle arrest and apoptosis of adult T-cell leukemia cells

Xue Tao Bai, Ramona Moles, Hassiba Chaib-Mezrag, Christophe Nicot

01.12.2015 | Research | Ausgabe 1/2015 Open Access

Model-based adaptive phase I trial design of post-transplant decitabine maintenance in myelodysplastic syndrome

Seunghoon Han, Yoo-Jin Kim, Jongtae Lee, Sangil Jeon, Taegon Hong, Gab-jin Park, Jae-Ho Yoon, Seung-Ah Yahng, Seung-Hwan Shin, Sung-Eun Lee, Ki-Seong Eom, Hee-Je Kim, Chang-Ki Min, Seok Lee, Dong-Seok Yim

01.12.2015 | Case report | Ausgabe 1/2015 Open Access

Complexity of FGFR signalling in metastatic urothelial cancer

Alejo Rodriguez-Vida, Matilde Saggese, Simon Hughes, Sarah Rudman, Simon Chowdhury, Neil R. Smith, Peter Lawrence, Claire Rooney, Brian Dougherty, Donal Landers, Elaine Kilgour, Hendrik-Tobias Arkenau

01.12.2015 | Research | Ausgabe 1/2015 Open Access

NLK functions to maintain proliferation and stemness of NSCLC and is a target of metformin

Dong Suwei, Zeng Liang, Liu Zhimin, Li Ruilei, Zou Yingying, Li Zhen, Ge Chunlei, Lai Zhangchao, Xue Yuanbo, Yang Jinyan, Li Gaofeng, Song Xin

01.12.2015 | Research | Ausgabe 1/2015 Open Access

Establishment and characterization of a novel MYC/BCL2 “double-hit” diffuse large B cell lymphoma cell line, RC

Lan V. Pham, Gary Lu, Archito T. Tamayo, Juan Chen, Pramoda Challagundla, Jeffrey L. Jorgensen, L. Jeffrey Medeiros, Richard J. Ford

01.12.2015 | Research | Ausgabe 1/2015 Open Access

Exosomes derived from miR-122-modified adipose tissue-derived MSCs increase chemosensitivity of hepatocellular carcinoma

Guohua Lou, Xiuli Song, Fan Yang, Shanshan Wu, Jing Wang, Zhi Chen, Yanning Liu

01.12.2015 | Commentary | Ausgabe 1/2015 Open Access

Nivolumab plus ipilimumab in the treatment of advanced melanoma

Katy K. Tsai, Adil I. Daud

01.12.2015 | Editorial | Ausgabe 1/2015 Open Access

Programmed death 1 blockade, an Achilles heel for MMR-deficient tumors?

Andy Yingjie Lin, Edward Lin

01.12.2015 | Research | Ausgabe 1/2015 Open Access

In vitro and in vivo single-agent efficacy of checkpoint kinase inhibition in acute lymphoblastic leukemia

Ilaria Iacobucci, Andrea Ghelli Luserna Di Rorà, Maria Vittoria Verga Falzacappa, Claudio Agostinelli, Enrico Derenzini, Anna Ferrari, Cristina Papayannidis, Annalisa Lonetti, Simona Righi, Enrica Imbrogno, Silvia Pomella, Claudia Venturi, Viviana Guadagnuolo, Federica Cattina, Emanuela Ottaviani, Maria Chiara Abbenante, Antonella Vitale, Loredana Elia, Domenico Russo, Pier Luigi Zinzani, Stefano Pileri, Pier Giuseppe Pelicci, Giovanni Martinelli

01.12.2015 | Rapid communication | Ausgabe 1/2015 Open Access

Overexpression of the long non-coding RNA PVT1 is correlated with leukemic cell proliferation in acute promyelocytic leukemia

Chengwu Zeng, Xibao Yu, Jing Lai, Lijiang Yang, Shaohua Chen, Yangqiu Li

01.12.2015 | Research | Ausgabe 1/2015 Open Access

Identification of plasma microRNA profiles for primary resistance to EGFR-TKIs in advanced non-small cell lung cancer (NSCLC) patients with EGFR activating mutation

Shuhang Wang, Xiaomei Su, Hua Bai, Jun Zhao, Jianchun Duan, Tongtong An, Minglei Zhuo, Zhijie Wang, Meina Wu, Zhenxiang Li, Jian Zhu, Jie Wang

01.12.2015 | Review | Ausgabe 1/2015 Open Access

Persistent androgen receptor addiction in castration-resistant prostate cancer

Michael T. Schweizer, Evan Y. Yu

01.12.2015 | Review | Ausgabe 1/2015 Open Access

ABT-199 (venetoclax) and BCL-2 inhibitors in clinical development

Shundong Cang, Chaitanya Iragavarapu, John Savooji, Yongping Song, Delong Liu

01.12.2015 | Review | Ausgabe 1/2015 Open Access

Bispecific antibodies and their applications

Gaowei Fan, Zujian Wang, Mingju Hao, Jinming Li

01.12.2015 | Erratum | Ausgabe 1/2015 Open Access

Erratum: Heritable GATA2 mutations associated with familial AML-MDS: a case report and review of literature

Juehua Gao, Ryan D. Gentzler, Andrew E. Timms, Marshall S. Horwitz, Olga Frankfurt, Jessica K. Altman, LoAnn C. Peterson

01.12.2015 | Research | Ausgabe 1/2015 Open Access

Roles of palmitoylation and the KIKK membrane-targeting motif in leukemogenesis by oncogenic KRAS4A

Huanbin Zhao, Ping Liu, Ruihong Zhang, Min Wu, Donghe Li, Xuemei Zhao, Chun Zhang, Bo Jiao, Bing Chen, Zhu Chen, Ruibao Ren

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