Ausgabe 1/2022
Inhalt (423 Artikel)
SCUBE3 downregulation modulates hepatocellular carcinoma by inhibiting CCNE1 via TGFβ/PI3K/AKT/GSK3β pathway
Pan Xu, Aoran Luo, Chuan Xiong, Hong Ren, Liang Yan, Qiang Luo
Combination therapy with immune checkpoint inhibitors (ICIs); a new frontier
Somayeh Vafaei, Angelina O. Zekiy, Ramadhan Ado Khanamir, Burhan Abdullah Zaman, Arman Ghayourvahdat, Hannaneh Azimizonuzi, Majid Zamani
The B7H4-PDL1 classifier stratifies immuno-phenotype in cervical cancer
Lingyan Chen, Jianfeng Dong, Zeying Li, Yu Chen, Yan Zhang
STK25 enhances hepatocellular carcinoma progression through the STRN/AMPK/ACC1 pathway
Yichao Zhang, Junhui Xu, Zhendong Qiu, Yongjun Guan, XiaoYi Zhang, Xin Zhang, Dongqi Chai, Chen Chen, Qinyong Hu, Weixing Wang
Switched alternative splicing events as attractive features in lung squamous cell carcinoma
Boxue He, Cong Wei, Qidong Cai, Pengfei Zhang, Shuai Shi, Xiong Peng, Zhenyu Zhao, Wei Yin, Guangxu Tu, Weilin Peng, Yongguang Tao, Xiang Wang
PHD finger protein 20-like protein 1 (PHF20L1) in ovarian cancer: from its overexpression in tissue to its upregulation by the ascites microenvironment
Dulce Rosario Alberto-Aguilar, Verónica Ivonne Hernández-Ramírez, Juan Carlos Osorio-Trujillo, Dolores Gallardo-Rincón, Alfredo Toledo-Leyva, Patricia Talamás-Rohana
Annexin A1 promotes the progression of bladder cancer via regulating EGFR signaling pathway
Piao Li, Lingling Li, Zhou Li, Shennan Wang, Ruichao Li, Weiheng Zhao, Yanqi Feng, Shanshan Huang, Lu Li, Hong Qiu, Shu Xia
Systematic analysis of the role of SLC52A2 in multiple human cancers
Lilong Zhang, Man Li, Zhoujun Cui, Dongqi Chai, Yongjun Guan, Chen Chen, Weixing Wang
Exome sequencing of glioblastoma-derived cancer stem cells reveals rare clinically relevant frameshift deletion in MLLT1 gene
Hany E. Marei, Asmaa Althani, Nahla Afifi, Anwarul Hasan, Thomas Caceci, Armando Felsani, Giuseppe Tringali, Ingrid Cifola, Giacomo Pozzoli, Carlo Cenciarelli
The prognosis biomarkers based on m6A-related lncRNAs for myeloid leukemia patients
Li-Rong Yang, Zhu-Ying Lin, Qing-Gang Hao, Tian-Tian Li, Yun Zhu, Zhao-Wei Teng, Jun Zhang
METTL3 promotes lung adenocarcinoma tumor growth and inhibits ferroptosis by stabilizing SLC7A11 m6A modification
Yiming Xu, Dandan Lv, Chao Yan, Hua Su, Xue Zhang, Yangfeng Shi, Kejing Ying
Induction and application of ferroptosis in cancer therapy
Qing Nie, Yue Hu, Xiao Yu, Xiao Li, Xuedong Fang
Hypoxia-mediated YTHDF2 overexpression promotes lung squamous cell carcinoma progression by activation of the mTOR/AKT axis
Peng Xu, Kang Hu, Ping Zhang, Zhi-Gang Sun, Nan Zhang
Comparison of mucin-1 in human breast cancer and canine mammary gland tumor: a review study
Rana Vafaei, Mitra Samadi, Aysooda Hosseinzadeh, Khadijeh Barzaman, MohammadReza Esmailinejad, Zohreh Khaki, Leila Farahmand
miR-133a targets YES1 to reduce cisplatin resistance in ovarian cancer by regulating cell autophagy
Yang Zhou, Chunyan Wang, Jinye Ding, Yingying Chen, Yaoqi Sun, Zhongping Cheng
LncRNA TP73‐AS1 promotes nasopharyngeal carcinoma progression through targeting miR-342-3p and M2 polarization via exosomes
Hongchao Yao, Linli Tian, Bingrui Yan, Like Yang, Yushan Li
Identification and validation of the high expression of pseudogene TCAM1P in cervical cancer via integrated bioinformatics analysis
Yuanhang Zhu, Chenchen Ren, Li Yang, Zhenan Zhang, Meiyuan Gong, Kebing Chen
Short-term starvation synergistically enhances cytotoxicity of Niraparib via Akt/mTOR signaling pathway in ovarian cancer therapy
Wang Zhi, Suting Li, Yuting Wan, Fuwen Wu, Li Hong
PTBP3 regulates proliferation of lung squamous cell carcinoma cells via CDC25A‐mediated cell cycle progression
Yingji Chen, Ying Ji, Suo Liu, Yicai Liu, Wei Feng, Longyu Jin
Correction to: Attenuated expression of SNF5 facilitates progression of bladder cancer via STAT3 activation
Hua Ding, Yaqin Huang, Jiazhong Shi, Liwei Wang, Sha Liu, Baixiong Zhao, Yuting Liu, Jin Yang, Zhiwen Chen
Development and validation of a novel 3-gene prognostic model for pancreatic adenocarcinoma based on ferroptosis-related genes
Jihua Yang, XiaoHong Wei, Fang Hu, Wei Dong, Liao Sun
The Prognostic value of the Fibrinogen to pre-albumin ratio in malignant tumors of the digestive system: a systematic review and meta-analysis
Baibei Li, Huachu Deng, Ziyan Zhou, Bo Tang
The functions and prognostic value of Krüppel‐like factors in breast cancer
Ke-Yun Zhu, Yao Tian, Ying-Xi Li, Qing-Xiang Meng, Jie Ge, Xu-Chen Cao, Ti Zhang, Yue Yu
SHC4 promotes tumor proliferation and metastasis by activating STAT3 signaling in hepatocellular carcinoma
Xin Zhang, Hongwei Zhang, Zhibin Liao, Jiacheng Zhang, Huifang Liang, Weixing Wang, Jia Yu, Keshuai Dong
Immune-related lncRNA classification of head and neck squamous cell carcinoma
Ruoyan Cao, Lin Cui, Jiayu Zhang, Xianyue Ren, Bin Cheng, Juan Xia
Correction to: NAP1L1 interacts with hepatoma-derived growth factor to recruit c-Jun inducing breast cancer growth
Shu Liu, Yewei Zhang, Shien Cui, Dajiang Song, Bo Li, Qian Chen, Guangyu Yao, Bin Gong
hsa_circ_0000231 Promotes colorectal cancer cell growth through upregulation of CCND2 by IGF2BP3/miR-375 dual pathway
Wei Zhang, Bo Wang, Yilin Lin, Yang Yang, Zhen Zhang, Quan Wang, Haoran Zhang, Kewei Jiang, Yingjiang Ye, Shan Wang, Zhanlong Shen
Application of artificial intelligence in a real-world research for predicting the risk of liver metastasis in T1 colorectal cancer
Tenghui Han, Jun Zhu, Xiaoping Chen, Rujie Chen, Yu Jiang, Shuai Wang, Dong Xu, Gang Shen, Jianyong Zheng, Chunsheng Xu
Study on the expression of TOP2A in hepatocellular carcinoma and its relationship with patient prognosis
Jiali Meng, Yuanchao Wei, Qing Deng, Ling Li, Xiaolong Li
Securin overexpression correlates with the activated Rb/E2F1 pathway and histone H3 epigenetic modifications in raw areca nut-induced carcinogenesis in mice
Nabamita Boruah, Chongtham Sovachandra Singh, Pooja Swargiary, Hughbert Dkhar, Anupam Chatterjee
MiR-937-3p promotes metastasis and angiogenesis and is activated by MYC in lung adenocarcinoma
Zijian Ma, Ganyi Chen, Yiqian Chen, Zizhang Guo, Hao Chai, Yu Tang, Lin Zheng, Ke Wei, Chunfeng Pan, Zhifei Ma, Yang Xia, Aiping Zhang
4,5-Dimethoxycanthin-6-one is a novel LSD1 inhibitor that inhibits proliferation of glioblastoma cells and induces apoptosis and pyroptosis
Wei Li, Bai-sheng Huang, Yuan-yuan Xiong, Li-jian Yang, Li-xiang Wu
Construction of a risk prediction model using m6A RNA methylation regulators in prostate cancer: comprehensive bioinformatic analysis and histological validation
Yongjun Quan, Xiaodong Zhang, Hao Ping
Periostin promotes the proliferation and metastasis of osteosarcoma by increasing cell survival and activates the PI3K/Akt pathway
Chaojian Xu, Ziyue Wang, Long Zhang, Yi Feng, Jia Lv, Zhuangzhuang Wu, Rong Yang, Taiyong Wu, Jian Li, Ruhao Zhou, Zhi Tian, Junjun Bai, Huadong Zhang, Yanping Lan, Zhi Lv
Golgi phosphoprotein 3 promotes angiogenesis and sorafenib resistance in hepatocellular carcinoma via upregulating exosomal miR-494-3p
Ying Gao, Zheng Yin, Yunling Qi, Hong Peng, Wenbin Ma, Ruizhi Wang, Wen Li
Addition of chemoradiotherapy to palliative chemotherapy in de novo metastatic nasopharyngeal carcinoma: a real-world study
Shuo-Han Zheng, Yu-Tong Wang, Song-Ran Liu, Zi-Lu Huang, Guan-Nan Wang, Jin-Tao Lin, Shi-Rong Ding, Chen Chen, Yun-Fei Xia
Retraction Note to: Degradation of long non-coding RNA-CIR decelerates proliferation, invasion and migration, but promotes apoptosis of osteosarcoma cells
Shiwei Liu, Jingchao Li, Liang Kang, Yueyang Tian, Yuan Xue
A novel prognostic model based on single-cell RNA sequencing data for hepatocellular carcinoma
Juan Lu, Yanfei Chen, Xiaoqian Zhang, Jing Guo, Kaijin Xu, Lanjuan Li
Green tea-derived theabrownin induces cellular senescence and apoptosis of hepatocellular carcinoma through p53 signaling activation and bypassed JNK signaling suppression
Jiaan Xu, Xiujuan Xiao, Bo Yan, Qiang Yuan, Xiaoqiao Dong, Quan Du, Jin Zhang, Letian Shan, Zhishan Ding, Li Zhou, Thomas Efferth
Identification of a novel HOOK3-FGFR1 fusion gene involved in activation of the NF-kappaB pathway
Xuehong Zhang, Furong Wang, Fanzhi Yan, Dan Huang, Haina Wang, Beibei Gao, Yuan Gao, Zhijie Hou, Jiacheng Lou, Weiling Li, Jinsong Yan
Patient-derived xenograft models in hepatopancreatobiliary cancer
Binhua Pan, Xuyong Wei, Xiao Xu
miR-199b-3p contributes to acquired resistance to cetuximab in colorectal cancer by targeting CRIM1 via Wnt/β-catenin signaling
Hu Han, Yan Li, Wan Qin, Lu Wang, Han Yin, Beibei Su, Xianglin Yuan
Nanotechnology-based advances in the efficient delivery of melatonin
Mohammad Mirza-Aghazadeh-Attari, Ainaz Mihanfar, Bahman Yousefi, Maryam Majidinia
ERBB3 binding protein 1 promotes the progression of malignant melanoma through activation of the Wnt/ β-catenin signaling pathway
Yanqiu Bao, Jingshu Cui, Yuyang Yue, Shuxia Cao, Xiangdan Li, Lan Liu
Correction to: Co-prevalence of human Papillomaviruses (HPV) and Epstein–Barr virus (EBV) in healthy blood donors from diverse nationalities in Qatar
Ishita Gupta, Gheyath K. Nasrallah, Anju Sharma, Ayesha Jabeen, Maria K. Smatti, Hamda A. Al-Thawadi, Ali A. Sultan, Moussa Alkhalaf, Semir Vranic, Ala-Eddin Al Moustafa
Correction to: Lymphocyte activating gene 3 protein expression in nasopharyngeal carcinoma is correlated with programmed cell death-1 and programmed cell death ligand-1, tumor-infiltrating lymphocytes
Fan Luo, Jiaxin Cao, Feiteng Lu, Kangmei Zeng, Wenjuan Ma, Yan Huang, Li Zhang, Hongyun Zhao
FOXM1-induced TYMS upregulation promotes the progression of hepatocellular carcinoma
Liang Wang, Caiyan Shi, Jie Yu, Yilin Xu
Dynamic regulation and functions of mRNA m6A modification
Shanshan Wang, Wei Lv, Tao Li, Shubing Zhang, Huihui Wang, Xuemei Li, Lianzi Wang, Dongyue Ma, Yan Zang, Jilong Shen, Yuanhong Xu, Wei Wei
Pan-cancer analysis combined with experiments explores the oncogenic role of spindle apparatus coiled-coil protein 1 (SPDL1)
Peng Song, Dilinaer Wusiman, Fenglan Li, Xiaoxuan Wu, Lei Guo, Wenbin Li, Shugeng Gao, Jie He
Antitumor responses in gastric cancer by targeting B7H3 via chimeric antigen receptor T cells
Fengqiang Sun, Xiaomei Yu, Ruixue Ju, Zhanzhao Wang, Yuhui Wang
LINC00665 up-regulates SIN3A expression to modulate the progression of colorectal cancer via sponging miR-138-5p
Shoushan Nan, Shuangxia Zhang, Rong Jin, Juelei Wang
ZMIZ2 promotes the development of triple-receptor negative breast cancer
Xiaopan Zou, Yan Liu, Jun Di, Wei Wei, Nobumoto Watanabe, Jiang Li, Xiaomeng Li
Cysteine cathepsin C: a novel potential biomarker for the diagnosis and prognosis of glioma
Xingbo Cheng, Zhishuai Ren, Zhendong Liu, Xiang Sun, Rongjun Qian, Chen Cao, Binfeng Liu, Jialin Wang, Hongbo Wang, Yuqi Guo, Yanzheng Gao
RNA-seq of nine canine prostate cancer cell lines reveals diverse therapeutic target signatures
Eva-Maria Packeiser, Leila Taher, Weibo Kong, Mathias Ernst, Julia Beck, Marion Hewicker-Trautwein, Bertram Brenig, Ekkehard Schütz, Hugo Murua Escobar, Ingo Nolte
Correction to: Exosomal lncRNA SNHG10 derived from colorectal cancer cells suppresses natural killer cell cytotoxicity by upregulating INHBC
Yiwen Huang, Yanbo Luo, Wentao Ou, Yuanyuan Wang, Dong Dong, Xiaowen Peng, Yuqi Luo
DNMT1 facilitates growth of breast cancer by inducing MEG3 hyper-methylation
Xiaotao Zhu, Lin Lv, Mingzheng Wang, Chen Fan, Xiaofeng Lu, Miaomiao Jin, Shuguang Li, Fan Wang
Spatial maps of hepatocellular carcinoma transcriptomes highlight an unexplored landscape of heterogeneity and a novel gene signature for survival
Nan Zhao, Yanhui Zhang, Runfen Cheng, Danfang Zhang, Fan Li, Yuhong Guo, Zhiqiang Qiu, Xueyi Dong, Xinchao Ban, Baocun Sun, Xiulan Zhao
DDX10 promotes the proliferation and metastasis of colorectal cancer cells via splicing RPL35
Xin Zhou, Zhihong Liu, Tengfei He, Cuifeng Zhang, Manman Jiang, Yuxiao Jin, Ziyu Wu, Changji Gu, Wei Zhang, Xiaodong Yang
Plasma tRNA-derived small RNAs signature as a predictive and prognostic biomarker in lung adenocarcinoma
Jun Wang, Xianyu Liu, Weifang Cui, Qun Xie, Wei Peng, Heng Zhang, Yang Gao, Chunfang Zhang, Chaojun Duan
Prognostic value of maximum standard uptake value, metabolic tumour volume, and total lesion glycolysis of 18F-FDG PET/CT in patients with malignant pleural mesothelioma: a systematic review and meta-analysis
Weibo Wen, Dongyuan Xu, Yongnan Piao, Xiangdan Li
Molecular evidence reveals thyrotropin intervention enhances the risk of developing radioiodine-refractory differentiated thyroid carcinoma
Hilda Samimi, Vahid Haghpanah
Development of a prognostic pyroptosis-related gene signature for head and neck squamous cell carcinoma patient
Weiwen Zhu, Jiayi Zhang, Mengyao Wang, Rundong Zhai, Yanbin Xu, Jie Wang, Mengqi Wang, Hang Zhang, Laikui Liu
Correction to: Blocking circ‑SCMH1 (hsa_circ_0011946) suppresses acquired DDP resistance of oral squamous cell carcinoma (OSCC) cells both in vitro and in vivo by sponging miR‑338‑3p and regulating LIN28B
Feng Qiu, Bin Qiao, Nan Zhang, Zheng Fang, Lu Feng, Shanfeng Zhang, Weiliu Qiu
The synergistic anticancer effect of the bromodomain inhibitor OTX015 and histone deacetylase 6 inhibitor WT-161 in osteosarcoma
Bo Yu, Lang Liu, Feng Cai, Yuanxiang Peng, Xiaofeng Tang, Duo Zeng, Teng Li, Feifei Zhang, Yiping Liang, Xuhui Yuan, Jiayu Li, Zhengzai Dai, Qi Liao, Xiao-Bin Lv
A role for the NPM1/PTPN14/YAP axis in mediating hypoxia-induced chemoresistance to sorafenib in hepatocellular carcinoma
Dengke Zhang, Fazong Wu, Jingjing Song, Miaomiao Meng, Xiaoxi Fan, Chenying Lu, Qiaoyou Weng, Shiji Fang, Liyun Zheng, Bufu Tang, Yang Yang, Jianfei Tu, Min Xu, Zhongwei Zhao, Jiansong Ji
As a prognostic biomarker of clear cell renal cell carcinoma RUFY4 predicts immunotherapy responsiveness in a PDL1-related manner
Daojia Miao, Jian Shi, Zhiyong Xiong, Wen Xiao, Xiangui Meng, Qingyang Lv, Kairu Xie, Hongmei Yang, Xiaoping Zhang
CPNE1 is a potential prognostic biomarker, associated with immune infiltrates and promotes progression of hepatocellular carcinoma
Jinfang Su, Yongbiao Huang, Yali Wang, Rui Li, Wanjun Deng, Hao Zhang, Huihua Xiong
Emerging role of non-coding RNAs in the regulation of KRAS
Soudeh Ghafouri-Fard, Zeinab Shirvani-Farsani, Bashdar Mahmud Hussen, Mohammad Taheri, Reza Jalili Khoshnoud
A novel immune-related lncRNA pair signature for prognostic prediction and immune response evaluation in gastric cancer: a bioinformatics and biological validation study
Jun Wang, Beidi Wang, Biting Zhou, Jing Chen, Jia Qi, Le Shi, Shaojun Yu, Guofeng Chen, Muxing Kang, Xiaoli Jin, Lie Wang, Jinghong Xu, Linghua Zhu, Jian Chen
FERMT1 contributes to the migration and invasion of nasopharyngeal carcinoma through epithelial–mesenchymal transition and cell cycle arrest
Lingling Li, Piao Li, Wei Zhang, Haiting Zhou, Ergang Guo, Guoqing Hu, Linli Zhang
Long non-coding RNAs as the critical regulators of epithelial mesenchymal transition in colorectal tumor cells: an overview
Amir Abbas Hamidi, Ghazaleh Khalili-Tanha, Zahra Nasrpour Navaei, Meysam Moghbeli
Comprehensive analysis of N6-methyladenosine regulators with the tumor immune landscape and correlation between the insulin-like growth factor 2 mRNA-binding protein 3 and programmed death ligand 1 in bladder cancer
Jianfeng Cui, Yaofeng Zhu, Xiaochen Liu, Wenfu Wang, Xuewen Jiang, Yangyang Xia, Guanwen Zhou, Shouzhen Chen, Benkang Shi
Modulation of the tumour microenvironment in hepatocellular carcinoma by tyrosine kinase inhibitors: from modulation to combination therapy targeting the microenvironment
Ruyin Chen, Qiong Li, Shuaishuai Xu, Chanqi Ye, Tian Tian, Qi Jiang, Jianzhen Shan, Jian Ruan
SGLT2 inhibition restrains thyroid cancer growth via G1/S phase transition arrest and apoptosis mediated by DNA damage response signaling pathways
Yan Wang, Longyan Yang, Lin Mao, Lijie Zhang, Yingjun Zhu, Yongsong Xu, Yanan Cheng, Rongxin Sun, Yuanyuan Zhang, Jing Ke, Dong Zhao
Sestrin2 reduces cancer stemness via Wnt/β-catenin signaling in colorectal cancer
Jinlai Wei, Xiangru Zheng, Wenjun Li, Xiaoli Li, Zhongxue Fu
ZHX2 inhibits thyroid cancer metastasis through transcriptional inhibition of S100A14
Yankun Zhang, Min Sun, Lifen Gao, Xiaohong Liang, Chunhong Ma, Jinghui Lu, Xuetian Yue
Correction to: Identification and validation of the high expression of pseudogene TCAM1P in cervical cancer via integrated bioinformatics analysis
Yuanhang Zhu, Chenchen Ren, Li Yang, Zhenan Zhang, Meiyuan Gong, Kebing Chen
Identification of key serum biomarkers for the diagnosis and metastatic prediction of osteosarcoma by analysis of immune cell infiltration
Zhihao Chen, Liubing Li, Ziyuan Li, Xi Wang, Mingxiao Han, Zongshuai Gao, Min Wang, Gangfeng Hu, Xiaolu Xie, Hong Du, Zonggang Xie, Haifang Zhang
NORAD-sponged miR-378c alleviates malignant behaviors of stomach adenocarcinoma via targeting NRP1
Yongjun Hu, Ming Luo
A pan-cancer analysis of molecular characteristics and oncogenic role of gasdermins
Mingchao Mu, Qiaoling Yu, Qin Zhang, Jing Guo, Xingjie Wang, Xuejun Sun, Junhui Yu
Circular RNA circ_IRAK3 contributes to tumor growth through upregulating KIF2A via adsorbing miR-603 in breast cancer
Fang Wang, Jingruo Li, Lin Li, Zhuo Chen, Nan Wang, Mingzhi Zhu, Hailong Mi, Youyi Xiong, Guangcheng Guo, Yuanting Gu
Application of CRISPR/Cas9-based mutant enrichment technique to improve the clinical sensitivity of plasma EGFR testing in patients with non-small cell lung cancer
Boyeon Kim, Yoonjung Kim, Saeam Shin, Seung-Tae Lee, Jae Yong Cho, Kyung-A. Lee
Exosomes derived from M2 type tumor-associated macrophages promote osimertinib resistance in non-small cell lung cancer through MSTRG.292666.16-miR-6836-5p-MAPK8IP3 axis
Xiaoying Wan, Boxiong Xie, Hui Sun, Weiqing Gu, Chunyan Wang, Qinfang Deng, Songwen Zhou
Clinicopathological and prognostic value of SIRT6 in patients with solid tumors: a meta-analysis and TCGA data review
Xiaojing Wu, Shuyuan Wang, Xuanzhu Zhao, Sizhen Lai, Zhen Yuan, Yixiang Zhan, Kemin Ni, Zhaoce Liu, Lina Liu, Ran Xin, Xingyu Zhou, Xin Yin, Xinyu Liu, Xipeng Zhang, Wei Cui, Chunze Zhang
Overexpression of CBS/H2S inhibits proliferation and metastasis of colon cancer cells through downregulation of CD44
Yuyang Zhang, Shanwen Chen, Jing Zhu, Shihao Guo, Taohua Yue, Hao Xu, Jianwen Hu, Zhihao Huang, Zeyang Chen, Pengyuan Wang, Yucun Liu
MeCP2 confers 5-fluorouracil resistance in gastric cancer via upregulating the NOX4/PKM2 pathway
Yannan Qin, Xiaoping Ma, Chen Guo, Shuang Cai, Hailin Ma, Lingyu Zhao
Differences in stem cell marker and osteopontin expression in primary and recurrent glioblastoma
Bülent Polat, Gisela Wohlleben, Rebekka Kosmala, Dominik Lisowski, Frederick Mantel, Victor Lewitzki, Mario Löhr, Robert Blum, Petra Herud, Michael Flentje, Camelia-Maria Monoranu
HOXA7 promotes the metastasis of KRAS mutant colorectal cancer by regulating myeloid-derived suppressor cells
Yunzhi Dang, Jiao Yu, Shuhong Zhao, Ximing Cao, Qing Wang
Comparison of porcine ALG and rabbit ATG on outcomes of HLA-haploidentical hematopoietic stem cell transplantation for patients with acquired aplastic anemia
Juan Chen, Yuanfeng Zhang, Xin Chen, Aiming Pang, Yuanqi Zhao, Li Liu, Runzhi Ma, Jialin Wei, Yi He, Donglin Yang, Rongli Zhang, Weihua Zhai, Qiaoling Ma, Erlie Jiang, Mingzhe Han, Jiaxi Zhou, Sizhou Feng
High AKAP8L expression predicts poor prognosis in esophageal squamous cell carcinoma
Qiu-yun Luo, Tian Di, Miao-Zhen Qiu, Zeng-fei Xia, Yong Du, Run-duan Lin, Li-qiong Yang, Yu-ting Sun, Da-Jun Yang, Jian Sun, Lin Zhang
The emerging role non-coding RNAs in B cell-related disorders
Soudeh Ghafouri-Fard, Tayyebeh Khoshbakht, Bashdar Mahmud Hussen, Mohammad Taheri, Elena Jamali
RNA helicase DHX15 decreases cell apoptosis by NF-κB signaling pathway in Burkitt lymphoma
Yuan Chen, Xianglei Chen, Lili Pan, Yuanmao Huang, Yuanhua Cai, Jinggang Li, Yang Li, Shaoyuan Wang
LINC01128 facilitates the progression of pancreatic cancer through up-regulation of LDHA by targeting miR-561-5p
Min Zhong, Zhi Fang, Bin Ruan, Jianping Xiong, Junhe Li, Zhiwang Song
HPV16 E6 gene polymorphisms and the functions of the mutation site in cervical cancer among Uygur ethnic and Han nationality women in Xinjiang, China
Huizhen Xin, Zhenzhen Pan, Xiangyi Zhe, Chunhe Zhang, Hongtao Li, Weinan Zheng, Haichen Long, Renfu Shao, Dongmei Li, Zemin Pan
A novel qualitative signature based on lncRNA pairs for prognosis prediction in hepatocellular carcinoma
Xiaoyun Bu, Luyao Ma, Shuang Liu, Dongsheng Wen, Anna Kan, Yujie Xu, Xuanjia Lin, Ming Shi
miR-223-3p carried by cancer-associated fibroblast microvesicles targets SORBS1 to modulate the progression of gastric cancer
Xiaoli Jin, Xi Qiu, Yi Huang, Hang Zhang, Kaibo Chen
Identification and validation a costimulatory molecule gene signature to predict the prognosis and immunotherapy response for hepatocellular carcinoma
Yinan Hu, Jingyi Liu, Jiahao Yu, Fangfang Yang, Miao Zhang, Yansheng Liu, Shuoyi Ma, Xia Zhou, Jingbo Wang, Ying Han
CD98hc has a pivotal role in maintaining the immuno-barrier integrity of basal layer cells in esophageal epithelium
Hao Ye, Xiang Li, Jing Lin, Peng Yang, Min Su
Prognostic biomarkers of malignant patients with pleural effusion: a systematic review and meta-analysis
Peng Peng, Yuan Yang, Juan Du, Kan Zhai, Huan-Zhong Shi
Pan-cancer analysis of oncogenic role of Programmed Cell Death 2 Like (PDCD2L) and validation in colorectal cancer
Huabin Gao, Cheng Xu, Jiangtao Liang, Songhan Ge, Fenfen Zhang, Ying Tuo, Huijuan Shi, Anjia Han
Pan-cancer analysis identifies LMNB1 as a target to redress Th1/Th2 imbalance and enhance PARP inhibitor response in human cancers
Haixiang Qin, Yingqiang Lu, Lin Du, Jingyan Shi, Haoli Yin, Bo Jiang, Wei Chen, Wenli Diao, Meng Ding, Wenmin Cao, Xuefeng Qiu, Xiaozhi Zhao, Hongqian Guo
CARM1 promotes gastric cancer progression by regulating TFE3 mediated autophagy enhancement through the cytoplasmic AMPK-mTOR and nuclear AMPK-CARM1-TFE3 signaling pathways
Suzhen Yang, Jing Zhang, Di Chen, Jiayi Cao, Ying Zheng, Yuying Han, Yirong Jin, Shuhui Wang, Ting Wang, Lin Ma, Tingting Luo, Yan Wang, Wen Qin, Lei Dong
miR-30a targets STOX2 to increase cell proliferation and metastasis in hydatidiform moles via ERK, AKT, and P38 signaling pathways
Zhenzhen Guo, Chenyu Zhu, Youhui Wang, Zhen Li, Lu Wang, Jianhui Fan, Yuefei Xu, Na Zou, Ying Kong, Dong Li, Linlin Sui
Long noncoding RNA SNHG17: a novel molecule in human cancers
Li Ma, Jin Gao, Niu Zhang, Jiawei Wang, Tianwei Xu, Tianyao Lei, Xiaoteng Zou, Chenchen Wei, Zhaoxia Wang
The importance of miRNA-630 in human diseases with an especial focus on cancers
Sepideh Kadkhoda, Soudeh Ghafouri-Fard
DAB2IP predicts treatment response and prognosis of ESCC patients and modulates its radiosensitivity through enhancing IR-induced activation of the ASK1-JNK pathway
Zhuting Tong, Weiyang Fang, Meng Xu, YeYe Xia, Rui Wang, Yue Li, Tianqi Zha, Liang Xiao, Shuhao Pan, Huiping Chai, Lei Zhao, Hao Wang, Huaguang Pan, Xiangcun Chen
DFNA5 regulates immune cells infiltration and exhaustion
Jian Hu, Wenceng Pei, Minren Jiang, Ying Huang, Fuyun Dong, Zhenyou Jiang, Ying Xu, Zihuang Li
The role of Th17 cells in the pathogenesis and treatment of breast cancer
Vahid Karpisheh, Majid Ahmadi, Kazem Abbaszadeh-Goudarzi, Mehran Mohammadpour Saray, Asal Barshidi, Hamed Mohammadi, Mehdi Yousefi, Farhad Jadidi-Niaragh
E2F6/KDM5C promotes SF3A3 expression and bladder cancer progression through a specific hypomethylated DNA promoter
Kai-Long Liu, Yue-Wei Yin, Bao-Sai Lu, Ya-Lin Niu, Dan-Dan Wang, Bei Shi, Hong Zhang, Ping-Ying Guo, Zhan Yang, Wei Li
MUC1 is a potential target to overcome trastuzumab resistance in breast cancer therapy
Aysooda Hosseinzadeh, Parnaz Merikhian, Nazanin Naseri, Mohammad Reza Eisavand, Leila Farahmand
AMICA1 is a diagnostic and prognostic biomarker and induces immune cells infiltration by activating cGAS-STING signaling in lung adenocarcinoma
Ziyang Feng, Yan Zhang, Min He, Ying Han, Changjing Cai, Shanshan Liu, Ping Liu, Yihong Chen, Hong Shen, Shan Zeng
DNA methyltransferase 1 inhibits microRNA-497 and elevates GPRC5A expression to promote chemotherapy resistance and metastasis in breast cancer
Yaobang Liu, Zhengyang Bai, Dahai Chai, Yali Gao, Ting Li, Yinling Ma, Jinping Li
Novel sequential therapy with metformin enhances the effects of cisplatin in testicular germ cell tumours via YAP1 signalling
Kancheng He, Zitaiyu Li, Kun Ye, Yihong Zhou, Minbo Yan, Hao Qi, Huating Hu, Yingbo Dai, Yuxin Tang
Rcl1 suppresses tumor progression of hepatocellular carcinoma: a comprehensive analysis of bioinformatics and in vitro experiments
Yu Jiaze, Hou Sinan, Yang Minjie, Zhou Yongjie, Du Nan, Wang Liangwen, Zhang Wen, Luo Jianjun, Yan Zhiping
High PPT1 expression predicts poor clinical outcome and PPT1 inhibitor DC661 enhances sorafenib sensitivity in hepatocellular carcinoma
Jianjun Xu, Zhe Su, Xiang Cheng, Shaobo Hu, Wenjie Wang, Tianhao Zou, Xing Zhou, Zifang Song, Yun Xia, Yang Gao, Qichang Zheng
LRP11-AS1 promotes the proliferation and migration of triple negative breast cancer cells via the miR-149-3p/NRP2 axis
Peng Li, Yu Zeng, Yudan Chen, Peng Huang, Xinchun Chen, Weidong Zheng
Identification of proteomic markers for prediction of the response to 5-Fluorouracil based neoadjuvant chemoradiotherapy in locally advanced rectal cancer patients
Jianan Wang, Jiayu Liu, Jinyang Wang, Shijian Wang, Feifei Li, Ruibing Li, Peng Liu, Mianyang Li, Chengbin Wang
Establishment and validation of a novel invasion-related gene signature for predicting the prognosis of ovarian cancer
Leilei Liang, Jian Li, Jing Yu, Jing Liu, Lin Xiu, Jia Zeng, Tiantian Wang, Ning Li, Lingying Wu
NCAPG facilitates colorectal cancer cell proliferation, migration, invasion and epithelial–mesenchymal transition by activating the Wnt/β-catenin signaling pathway
Yanlong Shi, Chang Ge, Debao Fang, Wei Wei, Li Li, Qian Wei, Hongzhu Yu
The regulation of autophagy by the miR-199a-5p/p62 axis was a potential mechanism of small cell lung cancer cisplatin resistance
Tiezhi Li, Helin Zhang, Zhichao Wang, Shaolin Gao, Xu Zhang, Haiyong Zhu, Na Wang, Honglin Li
BuFeiXiaoJiYin ameliorates the NLRP3 inflammation response and gut microbiota in mice with lung cancer companied with Qi-yin deficiency
Rui-yuan Jiang, Ting Wang, Qiao-yu Lan, Yan-chun Qin, Ting-ting Man, Hua Sun, Zhu-long Li, Xiao-ting Zhong, Chun-mei Mo, Zhen Rong
Tumor-associated macrophage derived IL-6 enriches cancer stem cell population and promotes breast tumor progression via Stat-3 pathway
N. N. V. Radharani, Amit S. Yadav, Ramakrishna Nimma, T. V. Santosh Kumar, Anuradha Bulbule, Venkatesh Chanukuppa, Dhiraj Kumar, Srinivas Patnaik, Srikanth Rapole, Gopal C. Kundu
Microarray analysis of breast cancer gene expression profiling in response to 2-deoxyglucose, metformin, and glucose starvation
Rita Aoun, Christopher El Hadi, Roula Tahtouh, Rita El Habre, George Hilal
Ferroptosis-related gene SLC1A5 is a novel prognostic biomarker and correlates with immune infiltrates in stomach adenocarcinoma
Dandan Zhu, Sifan Wu, Yafang Li, Yu Zhang, Jierong Chen, Jianhong Ma, Lixue Cao, Zejian Lyu, Tieying Hou
The effect of the polycystic ovary syndrome and hypothyroidism on the risk of fibrocystic breast changes: a meta-analysis
Parisa Kohnepoushi, Hojat Dehghanbanadaki, Pardis Mohammadzedeh, Maziar Nikouei, Yousef Moradi
MALAT1-related signaling pathways in colorectal cancer
Wen-Wen Xu, Jin Jin, Xiao-yu Wu, Qing-Ling Ren, Maryam Farzaneh
SLC4A4 promotes prostate cancer progression in vivo and in vitro via AKT-mediated signalling pathway
Zelin Liu, Qinghua Wang, Guanzhong Zhai, Shuai Ke, Xi Yu, Jia Guo
KRAS acting through ERK signaling stabilizes PD-L1 via inhibiting autophagy pathway in intrahepatic cholangiocarcinoma
Zheng Gao, Jia-Feng Chen, Xiao-Gang Li, Ying-Hong Shi, Zheng Tang, Wei-Ren Liu, Xin Zhang, Ao Huang, Xuan-Ming Luo, Qiang Gao, Guo-Ming Shi, Ai-Wu Ke, Jian Zhou, Jia Fan, Xiu-Tao Fu, Zhen-Bin Ding
Knockdown of RSPH14 inhibits proliferation, migration, and invasion and promotes apoptosis of hepatocellular carcinoma via RelA
Dawei Yuan, Rulan Ma, Tuanhe Sun, Kun Zhu, Chengxue Dang, Haixia Ye, Kang Li
The emerging role of deubiquitylating enzymes as therapeutic targets in cancer metabolism
Rongfu Tu, Junpeng Ma, Peng Zhang, Ye Kang, Xiaofan Xiong, Junsheng Zhu, Miao Li, Chengsheng Zhang
Correction to: Short‑term starvation synergistically enhances cytotoxicity of Niraparib via Akt/mTOR signaling pathway in ovarian cancer therapy
Zhi Wang, Suting Li, Yuting Wan, Fuwen Wu, Li Hong
The molecular mechanism of METTL3 promoting the malignant progression of lung cancer
Chao Ma, Rui-Jie Ma, Kang Hu, Qi-Ming Zheng, Ye-Peng Wang, Nan Zhang, Zhi-Gang Sun
Functions and underlying mechanisms of miR-650 in human cancers
Yuanshuai Su, Qiuxian Zheng, Lingxiao Zhu, Xinyu Gu, Juan Lu, Lanjuan Li
Correction: The dysbiosis signature of Fusobacterium nucleatum in colorectal cancer‑cause or consequences? A systematic review
Maryam Ranjbar, Rasoul Salehi, Shaghayegh Haghjooy Javanmard, Laleh Rafiee, Habibollah Faraji, Sima Jafarpour, Gordon A. Ferns, Majid Ghayour‑Mobarhan, Mostafa Manian, Reza Nedaeinia
Microbial and molecular differences according to the location of head and neck cancers
Yun Kyeong Kim, Eun Jung Kwon, Yeuni Yu, Jayoung Kim, Soo-Yeon Woo, Hee-Sun Choi, Munju Kwon, Keehoon Jung, Hyung-Sik Kim, Hae Ryoun Park, Dongjun Lee, Yun Hak Kim
BMI1 promotes osteosarcoma proliferation and metastasis by repressing the transcription of SIK1
Qiang Wang, Yinghui Wu, Meng Lin, Gaigai Wang, Jinyan Liu, Min Xie, Bo Zheng, Cong Shen, Jun Shen
Quantification of fibrinogen-to-pre-albumin ratio provides an integrating parameter for differential diagnosis and risk stratification of early-stage colorectal cancer
Hou-Qun Ying, Wei Chen, Cui-Fen Xiong, Yuanyuan Wang, Xiao-Juan Li, Xue-Xin Cheng
Genomic correlates of programmed cell death ligand 1 (PD-L1) expression in Chinese lung adenocarcinoma patients
Kang Li, Jun Liu, Lin Wu, Yajie Xiao, Jia Li, Haijian Du, Zhikun Zhao, Chao Sun, Yongtian Zhao, Jie Yang, Dongfang Wu, Zhuxiang Zhao, Bolin Chen
Investigating the role of peptides in effective therapies against cancer
Reza Naeimi, Asrin Bahmani, Saeid Afshar
MiR-323a-3p acts as a tumor suppressor by suppressing FMR1 and predicts better esophageal squamous cell carcinoma outcome
Yu Men, Yirui Zhai, Lihong Wu, Lipin Liu, Wenjue Zhang, Wei Jiang, Nan Bi, Yongmei Song, Zhouguang Hui, Luhua Wang
The function and regulation network mechanism of circRNA in liver diseases
Panpan Wang, Yunhuan Zhang, Lugang Deng, Zhi Qu, Peisen Guo, Limin Liu, Zengli Yu, Peixi Wang, Nan Liu
A systematic review of the therapeutic effects of resveratrol in combination with 5-fluorouracil during colorectal cancer treatment: with a special focus on the oxidant, apoptotic, and anti-inflammatory activities
Hossein Moutabian, Mehrsa Majdaeen, Ruhollah Ghahramani-Asl, Masoumeh Yadollahi, Esmaeil Gharepapagh, Gholamreza Ataei, Zahra Falahatpour, Hamed Bagheri, Bagher Farhood
A synthesized olean-28,13β-lactam targets YTHDF1-GLS1 axis to induce ROS-dependent metabolic crisis and cell death in pancreatic adenocarcinoma
Shijia Wu, Yong Ai, Huimin Huang, Guangyu Wu, Shipeng Zhou, Weilong Hong, Percy David Papa Akuetteh, Guihua Jin, Xingling Zhao, Yihua Zhang, Xiaolong Zhang, Linhua Lan
SNAP25 is a potential prognostic biomarker for prostate cancer
Longjiang Di, Maoli Gu, Yan Wu, Guoqiang Liu, Lishuo Zhang, Yifei Li, Wenjing Zhang
Pharmacological targeting transient receptor potential canonical channel 6 modulates biological behaviors for cervical cancer HeLa and SiHA cell
Li-ping Bai, Ya-li Chen, Ai Zheng
From inflammatory bowel disease to colorectal cancer: what’s the role of miRNAs?
Mostafa Vaghari-Tabari, Niloufar Targhazeh, Soheila Moein, Durdi Qujeq, Forough Alemi, Maryam Majidina, Simin Younesi, Zatollah Asemi, Bahman Yousefi
B7-H4 expression is upregulated by PKCδ activation and contributes to PKCδ-induced cell motility in colorectal cancer
Bin Zhou, Youwei Lu, Zhiming Zhao, Tongguo Shi, Hongya Wu, Weichang Chen, Liang Zhang, Xueguang Zhang
PTH2R is related to cell proliferation and migration in ovarian cancer: a multi-omics analysis of bioinformatics and experiments
Wang Xiaowei, Lu Tong, Qu Yanjun, Fan Lili
MicroRNA-146a promotes proliferation, migration, and invasion of HepG2 via regulating FLAP
Huihui Wang, Shubing Zhang, Tao Li, Lianzi Wang, Wei Lv, Shanshan Wang, Dongyue Ma, Yan Zang, Xinyue Zhu, Yuanhong Xu, Lan Zheng, Jilong Shen, Wei Wei
RPL15 promotes hepatocellular carcinoma progression via regulation of RPs-MDM2-p53 signaling pathway
Rui Shi, Zirong Liu
Molecular mechanism by which CDCP1 promotes proneural-mesenchymal transformation in primary glioblastoma
Zhiying Lin, Zhu Zhang, Haojie Zheng, Haiyan Xu, Yajuan Wang, Chao Chen, Junlu Liu, Guozhong Yi, Zhiyong Li, Xiaoyan Wang, Guanglong Huang
Correction to: CCR9 initiates epithelial–mesenchymal transition by activating Wnt/β-catenin pathways to promote osteosarcoma metastasis
Haoran Kong, Wenhui Yu, Zhuning Chen, Haonan Li, Guiwen Ye, Jiacong Hong, Zhongyu Xie, Keng Chen, Yanfeng Wu, Huiyong Shen
Exosomal miR-301a-3p from esophageal squamous cell carcinoma cells promotes angiogenesis by inducing M2 polarization of macrophages via the PTEN/PI3K/AKT signaling pathway
Yuwei Shou, Xiaoqian Wang, Chao Chen, Yinghao Liang, Chenbo Yang, Qiankun Xiao, Hui Li, Shuaiyuan Wang, Jiao Shu, Xiangyu Tian, Kuisheng Chen
Evaluation of mutagenesis, necrosis and apoptosis induced by omeprazole in stomach cells of patients with gastritis
Ana Maria Oliveira Ferreira da Mata, Marcia Fernanda Correia Jardim Paz, Ag-Anne Pereira Melo de Menezes, Antonielly Campinho dos Reis, Bruna da Silva Souza, Carlos Dimas de Carvalho Sousa, Sônia Alves Machado, Thiago Soares Gondim Medeiros, Chandan Sarkar, Muhammad Torequl Islam, Javad Sharifi-Rad, Sevgi Durna Daştan, Mohammed M. Alshehri, João Marcelo de Castro e Sousa, Ana Amélia de Carvalho Melo Cavalcante
Technique integration of single-cell RNA sequencing with spatially resolved transcriptomics in the tumor microenvironment
Hailan Yan, Jinghua Shi, Yi Dai, Xiaoyan Li, Yushi Wu, Jing Zhang, Zhiyue Gu, Chenyu Zhang, Jinhua Leng
Alpha-1-antichymotrypsin as a novel biomarker for diagnosis, prognosis, and therapy prediction in human diseases
Yanxia Jin, Weidong Wang, Qiyun Wang, Yueyang Zhang, Kashif Rafiq Zahid, Umar Raza, Yongsheng Gong
A novel risk score model based on five angiogenesis-related long non-coding RNAs for bladder urothelial carcinoma
Xinyuan Li, Chunlin Zhang, Xiang Peng, Yang Li, Guo Chen, Xin Gou, Xiang Zhou, Chao Ma
Prognostic value and biological function of LRRN4 in colorectal cancer
Cheng Xu, Yulin Chen, Feiwu Long, Junman Ye, Xue Li, Qiaorong Huang, Dejiao Yao, Xiaoli Wang, Jin Zhao, Wentong Meng, Xianming Mo, Ran Lu, Chuanwen Fan, Tao Zhang
Correction to: miR-223-3p carried by cancer-associated fibroblast microvesicles targets SORBS1 to modulate the progression of gastric cancer
Xiaoli Jin, Xi Qiu, Yi Huang, Hang Zhang, Kaibo Chen
Win or loss? Combination therapy does improve the oncolytic virus therapy to pancreatic cancer
Wenhao Luo, Yawen Wang, Taiping Zhang
Eukaryotic translation initiation factor 3 subunit B promotes head and neck cancer via CEBPB translation
Chengzhi Xu, Yupeng Shen, Yong Shi, Ming Zhang, Liang Zhou
Piezo1 promoted hepatocellular carcinoma progression and EMT through activating TGF-β signaling by recruiting Rab5c
Yi-ming Li, Cong Xu, Bo Sun, Fang-jing Zhong, Momo Cao, Lian-yue Yang
MiR-212 value in prognosis and diagnosis of cancer and its association with patient characteristics: a systematic review and meta-analysis
Sara Raji, Mehrdad Sahranavard, Mahdi Mottaghi, Amirhossein Sahebkar
Cell type-specific response of colon cancer tumor cell lines to oncolytic HSV-1 virotherapy in hypoxia
Sara Shayan, Arash Arashkia, Golnaz Bahramali, Asghar Abdoli, Mohammad Sadegh Shams Nosrati, Kayhan Azadmanesh
CircCASC15-miR-100-mTOR may influence the cervical cancer radioresistance
Tingting Yao, Yao Yao, Zhiliao Chen, Yongpai Peng, Guanglei Zhong, Chunxian Huang, Jing Li, Ruixin Li
Early versus delay oral feeding for patients after upper gastrointestinal surgery: a systematic review and meta-analysis of randomized controlled trials
Huachu Deng, Baibei Li, Xingan Qin
Cancer-associated fibroblasts and resistance to anticancer therapies: status, mechanisms, and countermeasures
Bing Feng, Jianzhong Wu, Bo Shen, Feng Jiang, Jifeng Feng
Integrated regulation of chondrogenic differentiation in mesenchymal stem cells and differentiation of cancer cells
Xiaohui Yang, Shifeng Tian, Linlin Fan, Rui Niu, Man Yan, Shuo Chen, Minying Zheng, Shiwu Zhang
Biological causes of immunogenic cancer cell death (ICD) and anti-tumor therapy; Combination of Oncolytic virus-based immunotherapy and CAR T-cell therapy for ICD induction
Amirhossein Mardi, Anastasia V. Shirokova, Rebar N. Mohammed, Ali Keshavarz, Angelina O. Zekiy, Lakshmi Thangavelu, Talar Ahmad Merza Mohamad, Faroogh Marofi, Navid Shomali, Amir Zamani, Morteza Akbari
Interaction between non-coding RNAs, mRNAs and G-quadruplexes
Soudeh Ghafouri-Fard, Atefe Abak, Aria Baniahmad, Bashdar Mahmud Hussen, Mohammad Taheri, Elena Jamali, Marcel E. Dinger
HOXC6 impacts epithelial-mesenchymal transition and the immune microenvironment through gene transcription in gliomas
Hui Huang, Zhengyuan Huo, Jiantong Jiao, Wei Ji, Jin Huang, Zheng Bian, Bin Xu, Junfei Shao, Jun Sun
Emerging role of circular RNAs in the pathogenesis of ovarian cancer
Soudeh Ghafouri-Fard, Tayyebeh Khoshbakht, Bashdar Mahmud Hussen, Mohammad Taheri, Majid Samsami
Genomic and immunological profiles of small-cell lung cancer between East Asians and Caucasian
Anqi Lin, Ningning Zhou, Weiliang Zhu, Jiexia Zhang, Ting Wei, Linlang Guo, Peng Luo, Jian Zhang
FGFR1 is a potential therapeutic target in neuroblastoma
Flora Cimmino, Annalaura Montella, Matilde Tirelli, Marianna Avitabile, Vito Alessandro Lasorsa, Feliciano Visconte, Sueva Cantalupo, Teresa Maiorino, Biagio De Angelis, Martina Morini, Aurora Castellano, Franco Locatelli, Mario Capasso, Achille Iolascon
Establishment and characterization of a novel ovarian high-grade serous carcinoma cell line—IPO43
Fernanda Silva, Filipa Coelho, Ana Peixoto, Pedro Pinto, Carmo Martins, Ann-Sophie Frombach, Vítor E. Santo, Catarina Brito, António Guimarães, Ana Félix
DNA repair and damage pathways in mesothelioma development and therapy
Faezeh Malakoti, Niloufar Targhazeh, Erfan Abadifard, Reza Zarezadeh, Sahar Samemaleki, Zatollah Asemi, Simin Younesi, Reza Mohammadnejad, Seyed Hadi Hossini, Ansar Karimian, Forough Alemi, Bahman Yousefi
ncRNAs-mediated high expression of TIMM8A correlates with poor prognosis and act as an oncogene in breast cancer
Zhonglin Wang, Shuqin Li, Feng Xu, Jingyue Fu, Jie Sun, XinLi Gan, Chuang Yang, Zhongqi Mao
PICALM exerts a role in promoting CRC progression through ERK/MAPK signaling pathway
Xitao Zhang, Tianlai Liu, Jinlin Huang, Jianping He
ZBTB7A, a miR-144-3p targeted gene, accelerates bladder cancer progression via downregulating HIC1 expression
Junqiang Liu, Zhiyuan Chou, Chun Li, Kai Huang, Xuejian Wang, Xiunan Li, Chuanchun Han, Abdullah Al-Danakh, Xiaodong Li, Xishuang Song
TNFRSF13B is a potential contributor to prostate cancer
Chia-Yang Li, Shu-Pin Huang, Yei-Tsung Chen, Hsin-En Wu, Wei-Chung Cheng, Chao-Yuan Huang, Chia-Cheng Yu, Victor C. Lin, Jiun-Hung Geng, Te-Ling Lu, Bo-Ying Bao
Myeloid cell leukemia-1 expression in cancers of the oral cavity: a scoping review
Su-Jung Choi, Neeti Swarup, Ji-Ae Shin, Seong-Doo Hong, Sung-Dae Cho
Long non-coding RNA LSAMP-1 is down-regulated in non-small cell lung cancer and predicts a poor prognosis
Wei Gong, Yinyan Li, Jianfeng Xian, Lei Yang, Yuanyuan Wang, Xin Zhang, Yifeng Zhou, Xinhua Wang, Guibin Qiao, Cuiyi Chen, Soham Datta, Xincheng Gao, Jiachun Lu, Fuman Qiu
Tetraspanin 7 promotes osteosarcoma cell invasion and metastasis by inducing EMT and activating the FAK-Src-Ras-ERK1/2 signaling pathway
Shijie Shao, Lianhua Piao, Liwei Guo, Jiangsong Wang, Luhui Wang, Jiawen Wang, Lei Tong, Xiaofeng Yuan, Junke Zhu, Sheng Fang, Yimin Wang
LINC00662 enhances cell progression and stemness in breast cancer by MiR-144-3p/SOX2 axis
Congjing An, Zhigang Hu, Yuehong Li, Pengxin Zhao, Runtian Liu, Qing Zhang, Peiling Zhu, Yanting Li, Ying Wang
Multi-omics analysis revealed TEK and AXIN2 are potential biomarkers in multifocal papillary thyroid cancer
Ga Hyun Kim, Hye Jin Heo, Ji Wan Kang, Eun-Kyung Kim, Seung Eun Baek, Keunyoung Kim, In Joo Kim, Sunghwan Suh, Byung-Joo Lee, Yun Hak Kim, Kyoungjune Pak
Activation of the chemokine receptor 3 pathway leads to a better response to immune checkpoint inhibitors in patients with metastatic urothelial carcinoma
Wenqin Feng, Anqi Lin, Le Sun, Ting Wei, Haoxuan Ying, Jian Zhang, Peng Luo, Weiliang Zhu
Integrative analysis identifies CXCL11 as an immune-related prognostic biomarker correlated with cell proliferation and immune infiltration in multiple myeloma microenvironment
Huizhong Wang, Ruonan Shao, Wenjian Liu, Shumei Peng, Shenrui Bai, Bibo Fu, Congling Zhao, Yue Lu
Comprehensive analyses reveal the carcinogenic and immunological roles of ANLN in human cancers
Yanlong Shi, Xinyu Ma, Menglu Wang, Sheng Lan, Haokun Jian, Yue Wang, Qian Wei, Fei Zhong
Decreased INPP5B expression predicts poor prognosis in lung adenocarcinoma
Jun Deng, Xu Lin, Qi Li, Xiao-yu Cai, Lin-wen Wu, Wei Wang, Bo Zhang, Yang-ling Li, Jian Hu, Neng-ming Lin
Exosomal microRNAs shuttling between tumor cells and macrophages: cellular interactions and novel therapeutic strategies
Wen-Xiu Xu, Dan-Dan Wang, Zhi-Qiang Zhao, He-Da Zhang, Su-Jin Yang, Qian Zhang, Lei Li, Jian Zhang
Silencing of histone deacetylase 3 suppresses the development of esophageal squamous cell carcinoma through regulation of miR-494-mediated TGIF1
Yang Yang, Yuan Zhang, Zongxiang Lin, Kai Wu, Zhanfeng He, Dengyan Zhu, Jia Zhao, Chunyang Zhang, Yuxia Fan
MiR-129-5p exerts Wnt signaling-dependent tumor-suppressive functions in hepatocellular carcinoma by directly targeting hepatoma-derived growth factor HDGF
Nicole Huge, Thea Reinkens, Reena Buurman, Maria Sandbothe, Anke Bergmann, Hannah Wallaschek, Beate Vajen, Amelie Stalke, Melanie Decker, Marlies Eilers, Vera Schäffer, Oliver Dittrich-Breiholz, Engin Gürlevik, Florian Kühnel, Brigitte Schlegelberger, Thomas Illig, Britta Skawran
ANLN and UBE2T are prognostic biomarkers associated with immune regulation in breast cancer: a bioinformatics analysis
Yu Xiao, Zhiqin Deng, Yongshen Li, Baoting Wei, Xiaoqiang Chen, Zhe Zhao, Yingjie Xiu, Meifang Hu, Murad Alahdal, Zhenhan Deng, Daping Wang, Jianquan Liu, Wencui Li
A review on the role of DANCR in the carcinogenesis
Soudeh Ghafouri-Fard, Tayyebeh Khoshbakht, Bashdar Mahmud Hussen, Aria Baniahmad, Mohammad Taheri, Mohammad Samadian
G-CSF upregulates the expression of aquaporin-9 through CEBPB to enhance the cytotoxic activity of arsenic trioxide to acute myeloid leukemia cells
Wanbin Fu, Gelan Zhu, Lan Xu, Jia Liu, Xiaofeng Han, Junying Wang, Xinpeng Wang, Jian Hou, Huanbin Zhao, Hua Zhong
Recent advances in targeted drug delivery systems for resistant colorectal cancer
Masoumeh Sharifi-Azad, Marziyeh Fathi, William C. Cho, Abolfazl Barzegari, Hamed Dadashi, Mehdi Dadashpour, Rana Jahanban-Esfahlan
KMT2B promotes the growth of renal cell carcinoma via upregulation of SNHG12 expression and promotion of CEP55 transcription
Jia-fu Feng, Jun Wang, Gang Xie, Yao-dong Wang, Xiao-han Li, Wen-yu Yang, Yu-wei Yang, Bin Zhang
LINC01806 mediated by STAT1 promotes cell proliferation, migration, invasion, and stemness in non-small cell lung cancer through Notch signaling by miR-4428/NOTCH2 axis
Shangxiao Huang, Shixiong Liang, Jianfeng Huang, Penghui Luo, Dunchang Mo, Hanlei Wang
N6-methyladenosine methylation modification patterns reveal immune profiling in pancreatic adenocarcinoma
Hao Xu, Lu Yin, Qianhui Xu, Jingjing Xiang, Rujun Xu
Revisiting characteristics of oncogenic extrachromosomal DNA as mobile enhancers on neuroblastoma and glioma cancers
Mohsen Karami Fath, Nastaran Karimfar, Andarz Fazlollahpour Naghibi, Shahriyar Shafa, Melika Ghasemi Shiran, Mehran Ataei, Hossein Dehghanzadeh, Mohsen Nabi Afjadi, Tahereh Ghadiri, Zahra Payandeh, Vahideh Tarhriz
PGM1 suppresses colorectal cancer cell migration and invasion by regulating the PI3K/AKT pathway
Zhewen Zheng, Xue Zhang, Jian Bai, Long Long, Di Liu, Yunfeng Zhou
Identification of icaritin derivative IC2 as an SCD-1 inhibitor with anti-breast cancer properties through induction of cell apoptosis
Chen Yang, Yi-Yuan Jin, Jie Mei, Die Hu, Xiaoyu Jiao, Hui-Lian Che, Chun-Lei Tang, Yan Zhang, Guo-Sheng Wu
YOD1 serves as a potential prognostic biomarker for pancreatic cancer
Zhishuo Zhang, Wenxia Zhao, Yiming Li, Yang Li, Hanzeng Cheng, Liyun Zheng, Xiaoyu Sun, Hao Liu, Rongguang Shao
Mechanisms of miR-3189-3p-mediated inhibition of c-MYC translation in triple negative breast cancer
Cecilia Vittori, Duane Jeansonne, Hassan Yousefi, Celeste Faia, Zhen Lin, Krzysztof Reiss, Francesca Peruzzi
Metallothionein 2A (MT2A) controls cell proliferation and liver metastasis by controlling the MST1/LATS2/YAP1 signaling pathway in colorectal cancer
Xi Liu, Jun Quan, Zhaolong Shen, Zequn Zhang, Zhijian Chen, Liang Li, Xiaorong Li, Gui Hu, Xiaofeng Deng
Anticancer potential of alkaloids: a key emphasis to colchicine, vinblastine, vincristine, vindesine, vinorelbine and vincamine
Praveen Dhyani, Cristina Quispe, Eshita Sharma, Amit Bahukhandi, Priyanka Sati, Dharam Chand Attri, Agnieszka Szopa, Javad Sharifi-Rad, Anca Oana Docea, Ileana Mardare, Daniela Calina, William C. Cho
A review on the role of PTENP1 in human disorders with an especial focus on tumor suppressor role of this lncRNA
Soudeh Ghafouri-Fard, Tayyebeh Khoshbakht, Bashdar Mahmud Hussen, Mohammad Taheri, Nader Akbari Dilmaghani
Radiotherapy-activated NBTXR3 nanoparticles modulate cancer cell immunogenicity and TCR repertoire
Audrey Darmon, Ping Zhang, Julie Marill, Naeemunnisa Mohamed Anesary, Jordan Da silva, Sébastien Paris
Emerging roles for lncRNA-NEAT1 in colorectal cancer
Shirin Azizidoost, Farhoodeh Ghaedrahmati, Omid Anbiyaee, Riyadh Ahmad Ali, Maryam Cheraghzadeh, Maryam Farzaneh
Retraction Note to: LncRNA SNHG12 regulates the radiosensitivity of cervical cancer through the miR-148a/CDK1 pathway
Chen Wang, Shiqing Shao, Li Deng, Shelian Wang, Yongyan Zhang
KCNN4 may weaken anti-tumor immune response via raising Tregs and diminishing resting mast cells in clear cell renal cell carcinoma
Yankang Cui, Tianyi Shen, Feng Xu, Jing Zhang, Yuhao Wang, Jiajin Wu, Hengtao Bu, Dian Fu, Bo Fang, Huichen Lv, Suchun Wang, Changjie Shi, Bianjiang Liu, Haowei He, Hao Tang, Jingping Ge
Recent knowledge of NFATc4 in oncogenesis and cancer prognosis
Qiu-Hua Zhong, Si-Wei Zha, Andy T. Y. Lau, Yan-Ming Xu
Thrombospondin-2 acts as a bridge between tumor extracellular matrix and immune infiltration in pancreatic and stomach adenocarcinomas: an integrative pan-cancer analysis
Xingchen Liao, Wei Wang, Baoping Yu, Shiyun Tan
DEPDC1B collaborates with GABRD to regulate ESCC progression
Yunfeng Yuan, Wei Ping, Ruijie Zhang, Zhipeng Hao, Ni Zhang
Long non-coding RNA MIR4435-2HG: a key molecule in progression of cancer and non-cancerous disorders
Majid Ghasemian, Masoumeh Rajabibazl, Unes Sahebi, Samira Sadeghi, Reza Maleki, Veys Hashemnia, Reza Mirfakhraie
CD40 monoclonal antibody and OK432 synergistically promote the activation of dendritic cells in immunotherapy
Juan Zhang, Lei Wang, Shuyi Li, Xuefeng Gao, Zhong Liu
Oncogenic functions and clinical significances of DCLK1 isoforms in colorectal cancer: a systematic review and meta-analysis
Elham Kalantari, Mahdieh Razmi, Fatemeh Tajik, Mohsen Asadi-Lari, Roya Ghods, Zahra Madjd
Comparison of anti-cancer effects of novel protein disulphide isomerase (PDI) inhibitors in breast cancer cells characterized by high and low PDIA17 expression
Anna Kurpińska, Joanna Suraj-Prażmowska, Marta Stojak, Joanna Jarosz, Łukasz Mateuszuk, Ewa Niedzielska-Andres, Magdalena Smolik, Joanna Wietrzyk, Ivars Kalvins, Maria Walczak, Stefan Chłopicki
Circular RNA EPB41 expression predicts unfavorable prognoses in NSCLC by regulating miR-486-3p/eIF5A axis-mediated stemness
Mingming Jin, Xiyu Liu, Yue Wu, Yuqing Lou, Xue Li, Gang Huang
Advances in biomarkers and techniques for pancreatic cancer diagnosis
Haotian Wu, Suwen Ou, Hongli Zhang, Rui Huang, Shan Yu, Ming Zhao, Sheng Tai
VEGF-B targeting by aryl hydrocarbon receptor mediates the migration and invasion of choriocarcinoma stem-like cells
Qianxia Tan, Jingting Cai, Jingping Peng, Cui Hu, ChenChun Wu, Huining Liu
Efficacy and safety of intravenous daratumumab-based treatments for AL amyloidosis: a systematic review and meta-analysis
Chunyan Sun, Xiaohong Wang, Renyi Zhang, Lingjie Xu, Bin Wang, Jian Li
GRB10 is a novel oncogene associated with cell proliferation and prognosis in glioma
Yuanbing Chen, Miao Tang, Jianbing Xiong, Qiongjue Gao, Wuyang Cao, Jun Huang
Lipid metabolism in tumor microenvironment: novel therapeutic targets
Xingkai Liu, Ping Zhang, Jing Xu, Guoyue Lv, Yan Li
A review on the role of MCM3AP-AS1 in the carcinogenesis and tumor progression
Soudeh Ghafouri-Fard, Tayyebeh Khoshbakht, Bashdar Mahmud Hussen, Mohammad Taheri, Mohammad Samadian
A novel signature derived from metabolism-related genes GPT and SMS to predict prognosis of laryngeal squamous cell carcinoma
Yujie Shen, Qiang Huang, Yifan Zhang, Chi-Yao Hsueh, Liang Zhou
Regulatory function of DNA methylation mediated lncRNAs in gastric cancer
Nan Li, Anqi Zeng, Qian Wang, Maohua Chen, Shaomi Zhu, Linjiang Song
LINC00893 inhibits the progression of prostate cancer through miR-3173-5p/SOCS3/JAK2/STAT3 pathway
Chuigong Yu, Yu Fan, Yu Zhang, Lupeng Liu, Gang Guo
Relationship between ATOH1 and tumor microenvironment in colon adenocarcinoma patients with different microsatellite instability status
Weiming Mou, Lingxuan Zhu, Tao Yang, Anqi Lin, Qiong Lyu, Linlang Guo, Zaoqu Liu, Quan Cheng, Jian Zhang, Peng Luo
A pan-cancer analysis of thioredoxin-interacting protein as an immunological and prognostic biomarker
Xuxue Guo, Mei Huang, Haonan Zhang, Qianhui Chen, Ying Hu, Yan Meng, Changjie Wu, Chenge Tu, Yongfeng Liu, Aimin Li, Qingyuan Li, Peirong Zhou, Side Liu
Depleting TMED3 alleviates the development of endometrial carcinoma
Jin Zhang, Yue Qi
The autophagy inducer trehalose stimulates macropinocytosis in NF1-deficient glioblastoma cells
Barbara Del Bello, Alessandra Gamberucci, Paola Marcolongo, Emilia Maellaro
Functional interplay between long non-coding RNAs and Breast CSCs
Bashdar Mahmud Hussen, Ramiar Kamal Kheder, Sara Tharwat Abdullah, Hazha Jamal Hidayat, Heshu Sulaiman Rahman, Abbas Salihi, Mohammad Taheri, Soudeh Ghafouri-Fard
CRISPR/Cas9 system in breast cancer therapy: advancement, limitations and future scope
Vamika Karn, Sandhya Sandhya, Wayne Hsu, Deepak Parashar, Himanshu Narayan Singh, Niraj Kumar Jha, Saurabh Gupta, Navneet Kumar Dubey, Sanjay Kumar
Induction of apoptosis and cell cycle arrest in colorectal cancer cells by novel anticancer metabolites of Streptomyces sp. 801
Arghavan Kouroshnia, Sirous Zeinali, Shiva Irani, Akram Sadeghi
DSF/Cu induces antitumor effect against diffuse large B-cell lymphoma through suppressing NF-κB/BCL6 pathways
Yunying Zhu, Chenshuang Lei, Qian Jiang, Qinhua Yu, Liannv Qiu
Toxic metals in the regulation of epithelial–mesenchymal plasticity: demons or angels?
Xu-Li Chen, Yan-Ming Xu, Andy T. Y. Lau
CircPDSS1 promotes the proliferation, invasion, migration, and EMT of breast cancer cell via regulating miR-320c/CKAP5 axis
Xia Liu, Jingyong Song, Yu Kang, Yaojia Wang, Anyue Chen
Myricetin: targeting signaling networks in cancer and its implication in chemotherapy
Zeeshan Javed, Khushbukhat Khan, Jesús Herrera-Bravo, Sajid Naeem, Muhammad Javed Iqbal, Qamar Raza, Haleema Sadia, Shahid Raza, Munir Bhinder, Daniela Calina, Javad Sharifi-Rad, William C. Cho
Oncogenic roles of the lncRNA LINC00460 in human cancers
Min Su, Jinming Tang, Desong Yang, Zhining Wu, Qianjin Liao, Hui Wang, Yuhang Xiao, Wenxiang Wang
The molecular biology and therapeutic potential of Nrf2 in leukemia
Atefeh Khodakarami, Sara Adibfar, Vahid Karpisheh, Shiva Abolhasani, Pooya Jalali, Hamed Mohammadi, Jamshid Gholizadeh Navashenaq, Mohammad Hojjat-Farsangi, Farhad Jadidi-Niaragh
Mechanism research and treatment progress of NAD pathway related molecules in tumor immune microenvironment
QinChen Xu, Xiaoyan Liu, Ghazal Mohseni, Xiaodong Hao, Yidan Ren, Yiwei Xu, Huiru Gao, Qin Wang, Yunshan Wang
Three-dimensional (3D) cell culture: a valuable step in advancing treatments for human hepatocellular carcinoma
Asmaa F. Khafaga, Shaker A. Mousa, Lotfi Aleya, Mohamed M. Abdel-Daim
β-Elemene alleviates cisplatin resistance in oral squamous cell carcinoma cell via inhibiting JAK2/STAT3 pathway in vitro and in vivo
Haiye Wang, Yingyi Ma
Nanobodies; new molecular instruments with special specifications for targeting, diagnosis and treatment of triple-negative breast cancer
Hamid Bakherad, Fahimeh Ghasemi, Maryam Hosseindokht, Hamed Zare
Targeting Ras-ERK cascade by bioactive natural products for potential treatment of cancer: an updated overview
Eunus S. Ali, Shamima Akter, Sarker Ramproshad, Banani Mondal, Thoufiqul Alam Riaz, Muhammad Torequl Islam, Ishaq N. Khan, Anca Oana Docea, Daniela Calina, Javad Sharifi-Rad, William C. Cho
Exercise and colorectal cancer: prevention and molecular mechanisms
Ramin Amirsasan, Maryam Akbarzadeh, Shabnam Akbarzadeh
STAT3-mediated upregulation of LINC00520 contributed to temozolomide chemoresistance in glioblastoma by interacting with RNA-binding protein LIN28B
Shuai Yuan, Qi Yan, Zhi-yong Zhao, Jing-long Zhang, He Zhang, Hang Yin, Zhi Yuan
Noncoding RNA-mediated molecular bases of chemotherapy resistance in hepatocellular carcinoma
Qikuan He, Pengyi Guo, Zhiyuan Bo, Haitao Yu, Jinhuan Yang, Yi Wang, Gang Chen
Clinical usefulness and acceleratory effect of macrophage inhibitory cytokine-1 on biliary tract cancer: an experimental biomarker analysis
Mitsuru Sugimoto, Rei Suzuki, Yoshihiro Nozawa, Tadayuki Takagi, Naoki Konno, Hiroyuki Asama, Yuki Sato, Hiroki Irie, Jun Nakamura, Mika Takasumi, Minami Hashimoto, Tsunetaka Kato, Ryoichiro Kobashi, Osamu Suzuki, Yuko Hashimoto, Takuto Hikichi, Hiromasa Ohira
A novel quantitative prognostic model for initially diagnosed non-small cell lung cancer with brain metastases
Xiaohui Li, Wenshen Gu, Yijun Liu, Xiaoyan Wen, Liru Tian, Shumei Yan, Shulin Chen
Nectin-4 promotes osteosarcoma progression and metastasis through activating PI3K/AKT/NF-κB signaling by down-regulation of miR-520c-3p
Yongheng Liu, Guanghao Li, Yan Zhang, Lili Li, Yanting Zhang, Xiaoyu Huang, Xianfu Wei, Peng Zhou, Ming Liu, Gang zhao, Jinyan Feng, Guowen Wang
Lymphocyte antigen 6G6D-mediated modulation through p38α MAPK and DNA methylation in colorectal cancer
Francesca Pia Caruso, Mario Rosario D’Andrea, Luigi Coppola, Matteo Landriscina, Valentina Condelli, Luigi Cerulo, Guido Giordano, Almudena Porras, Massimo Pancione
Role of PI3K/AKT pathway in squamous cell carcinoma with an especial focus on head and neck cancers
Soudeh Ghafouri-Fard, Ali Noie Alamdari, Yashar Noee Alamdari, Atefe Abak, Bashdar Mahmud Hussen, Mohammad Taheri, Elena Jamali
Potential of antibody–drug conjugates (ADCs) for cancer therapy
Hany E. Marei, Carlo Cenciarelli, Anwarul Hasan
Correction: Genistein as a regulator of signaling pathways and microRNAs in different types of cancers
Zeeshan Javed, Khushbukhat Khan, Jesús Herrera-Bravo, Sajid Naeem, Muhammad Javed Iqbal, Haleema Sadia, Qamar Raza Qadri, Shahid Raza, Asma Irshad, Ali Akbar, Željko Reiner, Ahmed Al-Harrasi, Ahmed Al-Rawahi, Dinara Satmbekova, Monica Butnariu, Iulia Cristina Bagiu, Radu Vasile Bagiu, Javad Sharifi-Rad
Potential mechanisms of quercetin in cancer prevention: focus on cellular and molecular targets
Parina Asgharian, Abbas Pirpour Tazekand, Kamran Hosseini, Haleh Forouhandeh, Tohid Ghasemnejad, Maryam Ranjbar, Muzaffar Hasan, Manoj Kumar, Sohrab Minaei Beirami, Vahideh Tarhriz, Saiedeh Razi Soofiyani, Latipa Kozhamzharova, Javad Sharifi-Rad, Daniela Calina, William C. Cho
Hormonal regulation of telomerase activity and hTERT expression in steroid-regulated tissues and cancer
Mohammad Taheri, Soudeh Ghafouri-Fard, Sajad Najafi, Julia Kallenbach, Elmira Keramatfar, Golnaz Atri Roozbahani, Mehdi Heidari Horestani, Bashdar Mahmud Hussen, Aria Baniahmad
Anti-cancer therapeutic strategies based on HGF/MET, EpCAM, and tumor-stromal cross talk
Khadijeh Barzaman, Rana Vafaei, Mitra Samadi, Mohammad Hossein Kazemi, Aysooda Hosseinzadeh, Parnaz Merikhian, Shima Moradi-Kalbolandi, Mohammad Reza Eisavand, Houra Dinvari, Leila Farahmand
A systematic review of anti-cancer roles and mechanisms of kaempferol as a natural compound
Elham Amjad, Babak Sokouti, Solmaz Asnaashari
Development and validation of a nomogram for evaluating the prognosis of immunotherapy plus antiangiogenic therapy in non-small cell lung cancer
Hao Huang, Yao Chen, Xuezi Weng, Sirou Li, Lin Zhang, Peisong Chen
Exosome-based strategies for diagnosis and therapy of glioma cancer
Mohsen Karami Fath, Jalil Azami, Alireza Masoudi, Reza Mosaddeghi Heris, Elnaz Rahmani, Fatemeh Alavi, Armina Alagheband Bahrami, Zahra Payandeh, Bahman Khalesi, Masoomeh Dadkhah, Navid Pourzardosht, Vahideh Tarhriz
Evolution of intra-tumoral heterogeneity across different pathological stages in papillary thyroid carcinoma
Ornella Affinito, Francesca Maria Orlandella, Neila Luciano, Marco Salvatore, Giuliana Salvatore, Monica Franzese
Circular RNA circWWC3 augments breast cancer progression through promoting M2 macrophage polarization and tumor immune escape via regulating the expression and secretion of IL-4
Yang Zheng, Shuguang Ren, Yu Zhang, Sihua Liu, Lingjiao Meng, Fei Liu, Lina Gu, Ning Ai, Meixiang Sang
The role of ferroptosis in esophageal cancer
Zimin Wang, Sikai Wu, Chengchu Zhu, Jianfei Shen
Antitumor immunity and therapeutic properties of marine seaweeds-derived extracts in the treatment of cancer
Mostafa M. El-Sheekh, Mohamed Nassef, Eman Bases, Shimaa El Shafay, Rania El-shenody
ITGAL infers adverse prognosis and correlates with immunity in acute myeloid leukemia
Ran Li, Xiaolu Wu, Kai Xue, Junmin Li
A comprehensive review about the utilization of immune checkpoint inhibitors and combination therapy in hepatocellular carcinoma: an updated review
Faezeh Sharafi, Sadegh Abaei Hasani, Samira Alesaeidi, Mohammad Saeed Kahrizi, Ali Adili, Shadi Ghoreishizadeh, Navid Shomali, Rozita Tamjidifar, Ramin Aslaminabad, Morteza Akbari
A review on the role of LINC01133 in cancers
Soudeh Ghafouri-Fard, Tayyebeh Khoshbakht, Bashdar Mahmud Hussen, Mohammad Taheri, Majid Mokhtari
Combination treatment with hENT1 and miR-143 reverses gemcitabine resistance in triple-negative breast cancer
Yue Xi, Ting Li, Yun Xi, Xinyi Zeng, Ying Miao, Rui Guo, Min Zhang, Biao Li
Molecular mechanisms of inhibitor of growth (ING) family members in health and malignancy
Mohammad Taheri, Bashdar Mahmud Hussen, Sajad Najafi, Atefe Abak, Soudeh Ghafouri-Fard, Majid Samsami, Aria Baniahmad
Correlation of the prognostic value of FNDC4 in glioblastoma with macrophage polarization
Hongwu Li, Xiaofei Yan, Shaowu Ou
Prostate cancer in omics era
Nasrin Gholami, Amin Haghparast, Iraj Alipourfard, Majid Nazari
Comprehensive analysis of the prognostic implications and functional exploration of PAK gene family in human cancer
Kunjian Lei, Min Luo, Zewei Tu, Shigang Lv, Junzhe Liu, Chuandong Gong, Minhua Ye, Miaojing Wu, Yilei Sheng, Xiaoyan Long, Jingying Li, Xingen Zhu, Kai Huang
Identification of genes with high heterogeneity of expression as a predictor of different prognosis and therapeutic responses in colorectal cancer: a challenge and a strategy
Ebrahim Salehitabar, Mohammad Mahdevar, Ali Valipour Motlagh, Farzad Seyed Forootan, Sara Feizbakhshan, Dina Zohrabi, Maryam Peymani
circ_0061265 competitively binds to microRNA-885-3p to promote the development of gastric cancer by upregulating AURKA expression
Qian Fei, Yuhe Lin, Mi Zhang, Jinshuai Guo, Yuan Liang
TRIM36 inhibits tumorigenesis through the Wnt/β-catenin pathway and promotes caspase-dependent apoptosis in hepatocellular carcinoma
Qing Tong, Mingyu Yi, Panpan Kong, Lin Xu, Wukui Huang, Yue Niu, Xiaojing Gan, Huan Zhan, Rui Tian, Dong Yan
Camels’ biological fluids contained nanobodies: promising avenue in cancer therapy
Nouf S. Al-Numair, Abdulrahman Theyab, Faisal Alzahrani, Anwar M. Shams, Ibrahim O. Al-Anazi, Atif Abdulwahab A. Oyouni, Osama M. Al-Amer, Charalampos Mavromatis, Islam M. Saadeldin, Wed A. Abdali, Yousef M. Hawsawi
Apoptosis evasion via long non-coding RNAs in colorectal cancer
Muhammad Irfan, Zeeshan Javed, Khushbukhat Khan, Naila Khan, Anca Oana Docea, Daniela Calina, Javad Sharifi-Rad, William C. Cho
miR-1908: a microRNA with diverse functions in cancers and non-malignant conditions
Soudeh Ghafouri-Fard, Tayyebeh Khoshbakht, Bashdar Mahmud Hussen, Mohammad Taheri, Majid Samsami
Emerging role of non-coding RNAs in the regulation of Sonic Hedgehog signaling pathway
Soudeh Ghafouri-Fard, Tayyebeh Khoshbakht, Bashdar Mahmud Hussen, Mohammad Taheri, Majid Samsami
Construction and validation of a ferroptosis-related long noncoding RNA signature in clear cell renal cell carcinoma
Zhenpeng Zhu, Cuijian Zhang, Jinqin Qian, Ninghan Feng, Weijie Zhu, Yang Wang, Yanqing Gong, Xuesong Li, Jian Lin, Liqun Zhou
Recent advances and limitations of mTOR inhibitors in the treatment of cancer
Eunus S. Ali, Kangkana Mitra, Shamima Akter, Sarker Ramproshad, Banani Mondal, Ishaq N. Khan, Muhammad Torequl Islam, Javad Sharifi-Rad, Daniela Calina, William C. Cho
A review on the role of MEG8 lncRNA in human disorders
Soudeh Ghafouri-Fard, Tayyebeh Khoshbakht, Bashdar Mahmud Hussen, Mohammad Taheri, Seyedpouzhia Shojaei
Intratumoral delivery of TransCon™ TLR7/8 Agonist promotes sustained anti-tumor activity and local immune cell activation while minimizing systemic cytokine induction
Luis Alejandro Zúñiga, Torben Leßmann, Karan Uppal, Nicola Bisek, Enping Hong, Caroline E. Rasmussen, Jens-Jakob Karlsson, Joachim Zettler, Lars Holten-Andersen, Kathy Bang, Dhruv Thakar, Yu-Chi Lee, Salomon Martinez, Simran Singh Sabharwal, Sebastian Stark, Frank Faltinger, Oliver Kracker, Samuel Weisbrod, Robin Müller, Tobias Voigt, Kornelia Bigott, Mohammad Tabrizifard, Vibeke Miller Breinholt, Amer M. Mirza, David B. Rosen, Kennett Sprogøe, Juha Punnonen
YY1 promotes pancreatic cancer cell proliferation by enhancing mitochondrial respiration
Bin Li, Junyi Wang, Jing Liao, Minghui Wu, Xiangshu Yuan, Hezhi Fang, Lijun Shen, Minghua Jiang
β-Escin overcomes trastuzumab resistance in HER2-positive breast cancer by targeting cancer stem-like features
Soeun Park, Jung Min Park, Minsu Park, Dongmi Ko, Seongjae Kim, Juyeon Seo, Kee Dal Nam, Eunsun Jung, Lee Farrand, Yoon-Jae Kim, Ji Young Kim, Jae Hong Seo
Crosstalk between tumor-associated macrophages and tumor cells promotes chemoresistance via CXCL5/PI3K/AKT/mTOR pathway in gastric cancer
Pengfei Su, Lin Jiang, Yingjing Zhang, Tian Yu, Weiming Kang, Yuqin Liu, Jianchun Yu
Multifaceted characterization of the biological and transcriptomic signatures of natural killer cells derived from cord blood and placental blood
Haibo Gao, Min Liu, Yawei Zhang, Leisheng Zhang, Baoguo Xie
Identification and validation of a ferroptosis-related gene to predict survival outcomes and the immune microenvironment in lung adenocarcinoma
Biao Deng, Jing Xiang, Zhu Liang, Lianxiang Luo
Exploring the relationship between autophagy and Gefitinib resistance in NSCLC by silencing PDLIM5 using ultrasound-targeted microbubble destruction technology
Yao Zhang, Wenhao Lv, Hui Li, Tiantian Dong, Hao Wu, Chunhong Su, Hong Shu, Fang Nie
Pancancer landscape analysis of the thymosin family identified TMSB10 as a potential prognostic biomarker and immunotherapy target in glioma
Ye Xiong, Yanhua Qi, Ziwen Pan, Shaobo Wang, Boyan Li, Bowen Feng, Hao Xue, Rongrong Zhao, Gang Li
METTL3 suppresses anlotinib sensitivity by regulating m6A modification of FGFR3 in oral squamous cell carcinoma
Jie Chen, Shuai Li, Zhexun Huang, Congyuan Cao, Anxun Wang, Qianting He
Construction of a ferroptosis-related five-lncRNA signature for predicting prognosis and immune response in thyroid carcinoma
Yuan Qin, Dai Zhang, Huan Zhang, Lan Hou, Zhe Wang, Liu Yang, Mingkun Zhang, Ge Zhao, Qing Yao, Rui Ling, Juliang Zhang
Mucosal-associated invariant T cells predict increased acute graft-versus-host-disease incidence in patients receiving allogeneic hematopoietic stem cell transplantation
Zhao Wang, Sudong Zhang, Xiaoyu Zhang, Li Liu, Lukun Zhou, Yuyan Shen, Rongli Zhang, Yi He, Donglin Yang, Erlie Jiang, Xiaoming Feng, Jiaxi Zhou, Tao Cheng, Mingzhe Han, Sizhou Feng
Disease-associated regulation of gene expression by resveratrol: Special focus on the PI3K/AKT signaling pathway
Soudeh Ghafouri-Fard, Zahra Bahroudi, Hamed Shoorei, Bashdar Mahmud Hussen, Seyedeh Fahimeh Talebi, Sadia Ghousia Baig, Mohammad Taheri, Seyed Abdulmajid Ayatollahi
Overexpression of CYP11A1 recovers cell cycle distribution in renal cell carcinoma Caki-1
Hien Thi My Ong, Tae-Hun Kim, Eda Ates, Jae-Chul Pyun, Min-Jung Kang
Establishment and validation of a novel prognostic model for non-virus-related hepatocellular carcinoma
Yu Jiang, Shulin Chen, Yaxian Wu, Yuanye Qu, Lina Jia, Qingxia Xu, Shuqin Dai, Ning Xue
N6-methyladenosine-related single-nucleotide polymorphism analyses identify oncogene RNFT2 in bladder cancer
Jiancheng Lv, Qiang Song, Kexin Bai, Jie Han, Hao Yu, Kai Li, Juntao Zhuang, Xiao Yang, Haiwei Yang, Qiang Lu
Correction: Identifying the novel key genes in renal cell carcinoma by bioinformatics analysis and cell experiments
Yeda Chen, Di Gu, Yaoan Wen, Shuxin Yang, Xiaolu Duan, Yongchang Lai, Jianan Yang, Daozhang Yuan, Aisha Khan, Wenqi Wu, Guohua Zeng
LINC00467: an oncogenic long noncoding RNA
Xuyu Chen, Qian Luo, Yanan Xiao, Jing Zhu, Yirao Zhang, Jie Ding, Juan Li
Cirsiliol regulates mitophagy in colon cancer cells via STAT3 signaling
Tao Jiang, Lulu Peng, Qian Wang, Bingyu Huang, Dewei Peng, Lintong Men, Yue Jiang, Mengying Zhu, Moran Wang, Li Lin, Jiagao Lv, Sheng Li
Sesquiterpenoid lactones as potential anti-cancer agents: an update on molecular mechanisms and recent studies
Praveen Dhyani, Priyanka Sati, Eshita Sharma, Dharam Chand Attri, Amit Bahukhandi, Bekzat Tynybekov, Agnieszka Szopa, Javad Sharifi-Rad, Daniela Calina, Hafiz A. R. Suleria, William C. Cho
Optical genome mapping identifies clinically relevant genomic rearrangements in prostate cancer biopsy sample
Yeeun Shim, Jongsoo Lee, Jieun Seo, Cheol Keun Park, Saeam Shin, Hyunho Han, Seung-Tae Lee, Jong Rak Choi, Byung Ha Chung, Young Deuk Choi
Evaluate the immune-related eRNA models and signature score to predict the response to immunotherapy in thyroid carcinoma
Pu Wu, Jinyuan Shi, Zhiyuan Wang, Wei Sun, Hao Zhang
Prediction of hepatocellular carcinoma prognosis and immunotherapeutic effects based on tryptophan metabolism-related genes
Chen Xue, Xinyu Gu, Yalei Zhao, Junjun Jia, Qiuxian Zheng, Yuanshuai Su, Zhengyi Bao, Juan Lu, Lanjuan Li
Etomoxir, a carnitine palmitoyltransferase 1 inhibitor, combined with temozolomide reduces stemness and invasiveness in patient-derived glioblastoma tumorspheres
Jin-Kyoung Shim, Seonah Choi, Seon-Jin Yoon, Ran Joo Choi, Junseong Park, Eun Hee Lee, Hye Joung Cho, Suji Lee, Wan-Yee Teo, Ju Hyung Moon, Hyun Sil Kim, Eui Hyun Kim, Jae-Ho Cheong, Jong Hee Chang, Jong In Yook, Seok-Gu Kang
CpG island status as an epigenetic alteration for NIS promoter in thyroid neoplasms; a cross-sectional study with a systematic review
Maryam Zarkesh, Noman Arab, Raziyeh Abooshahab, Shabnam Heydarzadeh, Sara Sheikholeslami, Zahra Nozhat, Marziyeh Salehi Jahromi, Seyed Ahmad Fanaei, Mehdi Hedayati
Multiomics surface receptor profiling of the NCI-60 tumor cell panel uncovers novel theranostics for cancer immunotherapy
Simon Heumos, Sandra Dehn, Konstantin Bräutigam, Marius C. Codrea, Christian M. Schürch, Ulrich M. Lauer, Sven Nahnsen, Michael Schindler
Midazolam exhibits antitumour and enhances the efficiency of Anti-PD-1 immunotherapy in hepatocellular carcinoma
Junwei Kang, Zhiying Zheng, Xian Li, Tian Huang, Dawei Rong, Xinyang Liu, Miaomiao Qin, Yuliang Wang, Xiangyi Kong, Jinhua Song, Chengyu Lv, Xiongxiong Pan
Current understanding of epigenetics role in melanoma treatment and resistance
Mohsen Karami Fath, Ali Azargoonjahromi, Asma Soofi, Faezeh Almasi, Shahnaz Hosseinzadeh, Saeed Khalili, Kamran Sheikhi, Saeid Ferdousmakan, Soroor Owrangi, Minoovash Fahimi, Hamidreza Zalpoor, Mohsen Nabi Afjadi, Zahra Payandeh, Navid Pourzardosht
STING pathway contributes to the prognosis of hepatocellular carcinoma and identification of prognostic gene signatures correlated to tumor microenvironment
Zhangya Pu, Jinghua Liu, Zelong Liu, Fang Peng, Yuanyuan Zhu, Xiaofang Wang, Jiayan He, Panpan Yi, Xingwang Hu, Xuegong Fan, Jiang Chen
Periostin: biology and function in cancer
Shima Dorafshan, Mahdieh Razmi, Sadegh Safaei, Erica Gentilin, Zahra Madjd, Roya Ghods
Notch-associated lncRNAs profiling circuiting epigenetic modification in colorectal cancer
Omnia Emam, Eman F. Wasfey, Nadia M. Hamdy
Characterization of pyruvate metabolism and citric acid cycle patterns predicts response to immunotherapeutic and ferroptosis in gastric cancer
Xu Wang, Bing Xu, Jing Du, Jun Xia, Guojie Lei, Chaoting Zhou, Jiayu Hu, Yinhao Zhang, Sufeng Chen, Fangchun Shao, Jiyun Yang, Yanchun Li
Matrix stiffness-dependent STEAP3 coordinated with PD-L2 identify tumor responding to sorafenib treatment in hepatocellular carcinoma
Shunxi Wang, Long Chen, Wanqian Liu
A review on the role of LINC00467 in the carcinogenesis
Soudeh Ghafouri-Fard, Tayyebeh Khoshbakht, Bashdar Mahmud Hussen, Mohammad Taheri, Mohammadreza Hajiesmaeili
Prognostic value of the modified systemic inflammation score in non-small-cell lung cancer with brain metastasis
Feng Wang, Limin Chen, Zhao Wang, Qiuyan Xu, He Huang, Hairong Wang, Xi Li, Mingjie Yu, Jiangen Chen, Fuhua Lin, Zhenghe Chen, Xiangheng Zhang, Qunying Yang, Yonggao Mou, Chengcheng Guo
Retraction Note: The novel long non-coding RNA LATS2-AS1-001 inhibits gastric cancer progression by regulating the LATS2/YAP1 signaling pathway via binding to EZH2
Dan Sun, Ying Wang, Huan Wang, Yan Xin
Identification of pyroptosis-related genes and long non-coding RNAs signatures in osteosarcoma
Jian Zhang, Jianjian Deng, Rui Ding, Jinghong Yuan, Jiahao Liu, Xiaokun Zhao, Tianlong Wu, Jingyu Jia, Xigao Cheng
Strategies to overcome the main challenges of the use of exosomes as drug carrier for cancer therapy
Bashdar Mahmud Hussen, Goran Sedeeq Hama Faraj, Mohammad Fatih Rasul, Hazha Jamal Hidayat, Abbas Salihi, Aria Baniahmad, Mohammad Taheri, Soudeh Ghafouri-Frad
SPP1 facilitates cell migration and invasion by targeting COL11A1 in lung adenocarcinoma
Xuan Yi, Linlin Luo, Yanzhen Zhu, Hong Deng, Huitian Liao, Yang Shen, Yan Zheng
A review on the role of cyclin dependent kinases in cancers
Soudeh Ghafouri-Fard, Tayyebeh Khoshbakht, Bashdar Mahmud Hussen, Peixin Dong, Nikolaus Gassler, Mohammad Taheri, Aria Baniahmad, Nader Akbari Dilmaghani
Integrated assessment of the clinical and biological value of ferroptosis-related genes in multiple myeloma
Bibo Fu, Ruonan Shao, Huizhong Wang, Guanjun Chen, Shenrui Bai, Hua Wang
Tumor-promoting myeloid cells in the pathogenesis of human oncoviruses: potential targets for immunotherapy
Azin Aghamajidi, Pooya Farhangnia, Salar Pashangzadeh, Amirmasoud Rayati Damavandi, Reza Jafari
Molecular subtypes based on cuproptosis-related genes and tumor microenvironment infiltration characterization in ovarian cancer
Jingjing Zhang, Miao Lu, Haoya Xu, Fang Ren, Liancheng Zhu
Human amniotic epithelial cells exert anti-cancer effects through secretion of immunomodulatory small extracellular vesicles (sEV)
Mohammad-Reza Bolouri, Roya Ghods, Kayhan Zarnani, Sedigheh Vafaei, Reza Falak, Amir-Hassan Zarnani
LncRNA XIST from the bone marrow mesenchymal stem cell derived exosome promotes osteosarcoma growth and metastasis through miR-655/ACLY signal
Guanghui Zhu, Yu Xia, Ziyue Zhao, Aoyu Li, Hui Li, Tao Xiao
Association of delayed chemoradiotherapy with elevated Epstein-Barr virus DNA load and adverse clinical outcome in nasopharyngeal carcinoma treatment during the COVID-19 pandemic: a retrospective study
Cheng-Long Huang, Xue-Liang Fang, Yan-Ping Mao, Rui Guo, Wen-Fei Li, Si-Si Xu, Jun Ma, Lei Chen, Ling-Long Tang
Outcome of autologous stem cell transplantation in patients with favorable-risk acute myeloid leukemia in first remission
Juan Chen, Li Liu, Runzhi Ma, Aiming Pang, Donglin Yang, Xin Chen, Jialin Wei, Yi He, Rongli Zhang, Weihua Zhai, Qiaoling Ma, Erlie Jiang, Mingzhe Han, Jiaxi Zhou, Sizhou Feng
Pomegranate juice and punicalagin-mediated chemoprevention of hepatocellular carcinogenesis via regulating miR-21 and NF-κB-p65 in a rat model
Aya M. Hussein, Nadia M. El-Beih, Menha Swellam, Enas A. El-Hussieny
DNA methylome in pancreatic cancer identified novel promoter hyper-methylation in NPY and FAIM2 genes associated with poor prognosis in Indian patient cohort
Ankita Chatterjee, Akash Bararia, Debopriyo Ganguly, Pronoy Kanti Mondal, Paromita Roy, Sudeep Banerjee, Shibajyoti Ghosh, Sumit Gulati, Supriyo Ghatak, Bitan Kumar Chattopadhay, Priyadarshi Basu, Aniruddha Chatterjee, Nilabja Sikdar
The pathogenic roles of lncRNA-Taurine upregulated 1 (TUG1) in colorectal cancer
Shirin Azizidoost, Ava Nasrolahi, Farhoodeh Ghaedrahmati, Bartosz Kempisty, Paul Mozdziak, Klaudia Radoszkiewicz, Maryam Farzaneh
Combinatorial targeting of menin and the histone methyltransferase DOT1L as a novel therapeutic strategy for treatment of chemotherapy-resistant ovarian cancer
Elena Alexandrova, Jessica Lamberti, Domenico Memoli, Claudia Quercia, Viola Melone, Francesca Rizzo, Roberta Tarallo, Giorgio Giurato, Giovanni Nassa, Alessandro Weisz
Identification of long non-coding RNA using single nucleotide epimutation analysis: a novel gene discovery approach
Mohammad Amin Kerachian, Marjan Azghandi
RBM10 regulates alternative splicing of lncRNA Neat1 to inhibit the invasion and metastasis of NSCLC
Shan Cong, Xin Di, Ranwei Li, Yingshu Cao, Xin Jin, Chang Tian, Min Zhao, Ke Wang
The expression changes of transcription factors including ANKZF1, LEF1, CASZ1, and ATOH1 as a predictor of survival rate in colorectal cancer: a large-scale analysis
Manizheh Sajadi, Mohammad Fazilti, Habibollah Nazem, Mohammad Mahdevar, Kamran Ghaedi
CHRNB2 represses pancreatic cancer migration and invasion via inhibiting β-catenin pathway
Cheng Qin, Tianhao Li, Yuanyang Wang, Bangbo Zhao, Zeru Li, Tianyu Li, Xiaoying Yang, Yutong Zhao, Weibin Wang
Intracellular and extracellular factors of colorectal cancer liver metastasis: a pivotal perplex to be fully elucidated
Yaru Niu, Wenwei Yang, Haili Qian, Yongkun Sun
A review on the role of mir-16-5p in the carcinogenesis
Soudeh Ghafouri-Fard, Tayyebeh Khoshbakht, Bashdar Mahmud Hussen, Sara Tharwat Abdullah, Mohammad Taheri, Mohammad Samadian
The function of prohibitins in mitochondria and the clinical potentials
Linda Oyang, Jian Li, Xianjie Jiang, Jinguan Lin, Longzheng Xia, Lixia Yang, Shiming Tan, Nayiyuan Wu, Yaqian Han, Yiqing Yang, Xia Luo, Jinyun Li, Qianjin Liao, Yingrui Shi, Yujuan Zhou
Transcriptome analysis of intestine from alk-SMase knockout mice reveals the effect of alk-SMase
Jiang Zhu, Lingqi Wang, Zhongwu Guo, Tao Zhang, Ping Zhang
Identification and validation of cuproptosis-related LncRNA signatures as a novel prognostic model for head and neck squamous cell cancer
Xiajing Liu, Wenwei Cheng, Heqing Li, Yexun Song
Integrated analysis to identify the AC005154.6/hsa-miR-29c-3p/CCNL2 axis as a novel prognostic biomarker associated with immune infiltration in prostate cancer
Qinyu Li, Bingliang Chen, Guoda Song, Kai Zeng, Xin Chen, Jianping Miao, Xianglin Yuan, Jihong Liu, Zhihua Wang, Bo Liu
SWI/SNF complex gene variations are associated with a higher tumor mutational burden and a better response to immune checkpoint inhibitor treatment: a pan-cancer analysis of next-generation sequencing data corresponding to 4591 cases
Yue Li, Xinhua Yang, Weijie Zhu, Yuxia Xu, Jiangjun Ma, Caiyun He, Fang Wang
The prognostic impact of the immune microenvironment in small-cell neuroendocrine carcinoma of the uterine cervix: PD-L1 and immune cell subtypes
Xiaoying Sun, Lili Liu, Ting Wan, Qidan Huang, Jieping Chen, Rongzhen Luo, Jihong Liu
Role of HOXA9 in solid tumors: mechanistic insights and therapeutic potential
Ling Tang, Lin Peng, Chao Tan, Huai Liu, Pan Chen, Hui Wang
HER2 amplification by next-generation sequencing to identify HER2-positive invasive breast cancer with negative HER2 immunohistochemistry
Laura Morsberger, Aparna Pallavajjala, Patty Long, Melanie Hardy, Rebecca Park, Rebecca Parish, Azin Nozari, Ying S. Zou
Establishment of anti-DKK3 peptide for the cancer control in head and neck squamous cell carcinoma (HNSCC)
Naoki Katase, Shin-ichiro Nishimatsu, Akira Yamauchi, Shinji Okano, Shuichi Fujita
Tumor cell-derived asymmetric dimethylarginine regulates macrophage functions and polarization
Yi-Ling Chen, AKaychia T. Lowery, Samuel Lin, Ameae M. Walker, Kuan-Hui E. Chen
The RNA demethylase ALKBH5 promotes the progression and angiogenesis of lung cancer by regulating the stability of the LncRNA PVT1
Wenyi Shen, Juan Pu, Zhi Zuo, Shanye Gu, Jing Sun, Bing Tan, Lili Wang, Jianmeng Cheng, Yangsong Zuo
Biosensing chips for cancer diagnosis and treatment: a new wave towards clinical innovation
Muhammad Javed Iqbal, Zeeshan Javed, Jesús Herrera-Bravo, Haleema Sadia, Faiza Anum, Shahid Raza, Arifa Tahir, Muhammad Naeem Shahwani, Javad Sharifi-Rad, Daniela Calina, William C. Cho
Induction of oxidative DNA damage, cell cycle arrest and p53 mediated apoptosis by calcium titanate nanoparticles in MCF-7 breast cancer cells
Hanan R. H. Mohamed, Maria M. H. Ibrahim, Ayman Diab
New strategy for antimetastatic treatment of lung cancer: a hypothesis based on circulating tumour cells
Zujun Que, Jianhui Tian
The prognostic value of IPI in patients with primary breast lymphoma, a multicenter retrospective study
Kexin Feng, Shuangtao Zhao, Qingyao Shang, Guangdong Qiao, Jiaxiang Liu, Chenxuan Yang, Ya Wei, Yalun Li, Fei Ren, Lixue Xuan, Xiang Wang, Xin Wang
Potential use of EGFR-targeted molecular therapies for tumor suppressor CYLD-negative and poor prognosis oral squamous cell carcinoma with chemoresistance
Ayumi Kanemaru, Satoru Shinriki, Mimi Kai, Kanae Tsurekawa, Kazuya Ozeki, Shota Uchino, Naoki Suenaga, Kou Yonemaru, Shunsuke Miyake, Takeshi Masuda, Ryusho Kariya, Seiji Okada, Hisashi Takeshita, Yuki Seki, Hiromu Yano, Yoshihiro Komohara, Ryoji Yoshida, Hideki Nakayama, Jian-Dong Li, Hideyuki Saito, Hirofumi Jono
Circular RNA circPTPRF promotes the progression of GBM via sponging miR-1208 to up-regulate YY1
Jiang Zhou, Chengbin Wang, Yingliang Liu, Daming Cui, Zhenlin Wang, Yang Jiang, Liang Gao
Development and validation of a risk prediction model for overall survival in patients with nasopharyngeal carcinoma: a prospective cohort study in China
Siwei Miao, Haike Lei, Xiaosheng Li, Wei Zhou, Guixue Wang, Anlong Sun, Ying Wang, Yongzhong Wu
Role of CC-chemokine ligand 2 in gynecological cancer
Jia-Jia Zhang, Wei Liu, Guo-Zhen Xing, Li Xiang, Wen-Ming Zheng, Zhen-Ling Ma
Targeted blocking of CCR2 and CXCR2 improves the efficacy of transarterial chemoembolization of hepatocarcinoma
Zhiqiang Tian, Xiaojuan Hou, Wenting Liu, Changchun Shao, Lu Gao, Jinghua Jiang, Li Zhang, Zhipeng Han, Lixin Wei
Immune checkpoint inhibitor-related adverse cardiac events in patients with lung cancer: a systematic review and meta-analysis
Xiao-Tong Zhang, Nan Ge, Zi-Jian Xiang, Tao Liu
Extracellular matrix stiffness mediates radiosensitivity in a 3D nasopharyngeal carcinoma model
Yanhua Fang, Shanshan Liang, Jianong Gao, Zhe Wang, Cheng Li, Ruoyu Wang, Weiting Yu
CAR-T cell combination therapy: the next revolution in cancer treatment
Maysoon Al-Haideri, Santalia Banne Tondok, Salar Hozhabri Safa, Ali Heidarnejad maleki, Samaneh Rostami, Abduladheem Turki Jalil, Moaed E. Al-Gazally, Fahad Alsaikhan, Jasur Alimdjanovich Rizaev, Talar Ahmad Merza Mohammad, Safa Tahmasebi
Spatial metabolomics on liver cirrhosis to hepatocellular carcinoma progression
Michelle Junyi He, Wenjun Pu, Xi Wang, Xiaoni Zhong, Dong Zhao, Zhipeng Zeng, Wanxia Cai, Jiayi Liu, Jianrong Huang, Donge Tang, Yong Dai
Intercellular crosstalk between cancer cells and cancer-associated fibroblasts via extracellular vesicles
Yutaka Naito, Yusuke Yoshioka, Takahiro Ochiya
Tiliroside suppresses triple-negative breast cancer as a multifunctional CAXII inhibitor
Rui Han, Hongxing Yang, Changquan Ling, Lingeng Lu
Molecular mechanism of circRNAs in drug resistance in renal cell carcinoma
Shuang Qin, Yuting Wang, Peijun Wang, Qi Lv
Modifying oncolytic virotherapy to overcome the barrier of the hypoxic tumor microenvironment. Where do we stand?
Sara Shayan, Arash Arashkia, Kayhan Azadmanesh
Activation of embryonic/germ cell-like axis links poor outcomes of gliomas
Zhan Ma, Fengyu Zhang, Ji Xiong, Haishi Zhang, Hui-Kuan Lin, Chunfang Liu
Correction: Transcriptome analysis of intestine from alk-SMase knockout mice reveals the effect of alk-SMase
Jiang Zhu, Lingqi Wang, Zhongwu Guo, Tao Zhang, Ping Zhang
Specific lncRNA signatures discriminate childhood acute leukaemias: a pilot study
Lorena Buono, Concetta Iside, Antonia De Matteo, Pio Stellato, Giuliana Beneduce, Roberta Penta de Vera d’Aragona, Rosanna Parasole, Marco Salvatore, Giovanni Smaldone, Peppino Mirabelli
Multidrug resistance genes screening of pancreatic ductal adenocarcinoma based on sensitivity profile to chemotherapeutic drugs
Bangbo Zhao, Cheng Qin, Zeru Li, Yuanyang Wang, Tianhao Li, Hongtao Cao, Xiaoying Yang, Tianyu Li, Weibin Wang
Transcription factor c-Rel regulated by E5 affects the whole process after HPV16 infection through miR-133a-modulated feedback loop aim at mir-379-369 cluster
Juan Zhou, Yongpeng Li, Ke Xu, Yan Rong, Siting Huang, Hailun Wu, Xianlin Yi, Chanzhen Liu
Identifying novel interactions of the colon-cancer related APC protein with Wnt-pathway nuclear transcription factors
Nayra M. Al-Thani, Stephanie Schaefer-Ramadan, Jovana Aleksic, Yasmin A. Mohamoud, Joel A. Malek
NRP1 inhibition modulates radiosensitivity of medulloblastoma by targeting cancer stem cells
Manon Douyère, Caifeng Gong, Mylène Richard, Nadia Pellegrini-Moïse, Joël Daouk, Julien Pierson, Pascal Chastagner, Cédric Boura
Exosomal circular RNA: a signature for lung cancer progression
Bashdar Mahmud Hussen, Snur Rasool Abdullah, Goran Sedeeq Hama Faraj, Mohammed Fatih Rasul, Abbas Salihi, Soudeh Ghafouri-Fard, Mohammad Taheri, Majid Mokhtari
Are chemical compounds in medical mushrooms potent against colorectal cancer carcinogenesis and antimicrobial growth?
John M. Macharia, Lu Zhang, Ruth W. Mwangi, Nora Rozmann, Zsolt Kaposztas, Tímea Varjas, Miklós Sugár, Huda Alfatafta, Márton Pintér, Raposa L. Bence
HDACs/mTOR inhibitor synergizes with pyrotinib in HER2-positive pancreatic cancer through degradation of mutant P53
Tiebo Mao, Xiaofei Zhang, Haiyan Xu, Xiao Zhang, Weiyu Ge, Shumin Li, Jingyu Ma, Ming Yue, Shengbai Xue, Jiujie Cui, Liwei Wang
Role of microRNA-34b-5p in cancer and injury: how does it work?
Xuechun Bai, Lianwen Zheng, Ying Xu, Yan Liang, Dandan Li
Identification and validation of an E2F-related gene signature for predicting recurrence-free survival in human prostate cancer
Cheng Yang, Lei Chen, Qingsong Niu, Qintao Ge, Jiong Zhang, Junyue Tao, Jun Zhou, Chaozhao Liang
Landmarks in pancreatic cancer studies
Fan Xu, Min Huang, Yun Bai, Xueshi Yin, Jingzhe Yan, Fangfang Liu, Jie Chen, Xiechuan Weng
Correction: FOXM1-induced TYMS upregulation promotes the progression of hepatocellular carcinoma
Liang Wang, Caiyan Shi, Jie Yu, Yilin Xu
METTL3 promotes glycolysis and cholangiocarcinoma progression by mediating the m6A modification of AKR1B10
Jingli Cai, Zheng Cui, Jingyi Zhou, Bosen Zhang, Ruiqi Lu, Youcheng Ding, Hai Hu
Luteolin: a flavonoid with a multifaceted anticancer potential
Parteek Prasher, Mousmee Sharma, Sachin Kumar Singh, Monica Gulati, Dinesh Kumar Chellappan, Flavia Zacconi, Gabriele De Rubis, Gaurav Gupta, Javad Sharifi-Rad, William C. Cho, Kamal Dua
The anterior gradient homologue 2 (AGR2) co-localises with the glucose-regulated protein 78 (GRP78) in cancer stem cells, and is critical for the survival and drug resistance of recurrent glioblastoma: in situ and in vitro analyses
Deema Hussein, Reem Alsereihi, Abdulla Ahmed A. Salwati, Rinad Algehani, Alazouf Alhowity, Ahmed M. Al-Hejin, Hans-Juergen Schulten, Saleh Baeesa, Mohammed Bangash, Fahad Alghamdi, Richard Cross, Torki Al Zughaibi, Mohamad Saka, Adeel Chaudhary, Adel Abuzenadah
BI-847325, a selective dual MEK and Aurora kinases inhibitor, reduces aggressive behavior of anaplastic thyroid carcinoma on an in vitro three-dimensional culture
Hilda Samimi, Rezvan Tavakoli, Parviz Fallah, Alireza Naderi Sohi, Maryam Amini Shirkouhi, Mahmood Naderi, Vahid Haghpanah
Glioblastoma cells have increased capacity to repair radiation-induced DNA damage after migration to the olfactory bulb
Charlotte Degorre, Ian C. Sutton, Stacey L. Lehman, Uma T. Shankavaram, Kevin Camphausen, Philip J. Tofilon
Exosomal LINC00460/miR-503-5p/ANLN positive feedback loop aggravates pancreatic cancer progression through regulating T cell–mediated cytotoxicity and PD-1 checkpoint
Jun Yao, Ruoyu Gao, Minghan Luo, Defeng Li, Liliangzi Guo, Zichao Yu, Feng Xiong, Cheng Wei, Benhua Wu, Zhenglei Xu, Dingguo Zhang, Jianyao Wang, Lisheng Wang
Evaluation of X-ray and carbon-ion beam irradiation with chemotherapy for the treatment of cervical adenocarcinoma cells in 2D and 3D cultures
Kazumasa Sekihara, Hidetomo Himuro, Nao Saito, Yukihide Ota, Taku Kouro, Yohsuke Kusano, Shinichi Minohara, Ryoichi Hirayama, Hiroyuki Katoh, Tetsuro Sasada, Daisuke Hoshino
Potential of Z-100, extracted from Mycobacterium tuberculosis strain Aoyama B, as a hot tumor inducer
Takayuki Horii, Yuki Orikawa, Yuta Ohira, Runa Eta, Nobuyoshi Kobayashi, Takanori Sato, Takeshi Watanabe, Takao Tanaka
CD5L-associated gene analyses highlight the dysregulations, prognostic effects, immune associations, and drug-sensitivity predicative potentials of LCAT and CDC20 in hepatocellular carcinoma
Xiuzhi Zhang, Xiaoli Liu, Keke Zhu, Xue Zhang, Ningning Li, Tao Sun, Shasha Fan, Liping Dai, Jinzhong Zhang
Current methods for studying metastatic potential of tumor cells
Pavla Bouchalova, Pavel Bouchal
Involvement of abnormal dystroglycan expression and matriglycan levels in cancer pathogenesis
Cristina Quereda, Àngels Pastor, José Martín-Nieto
LncRNA HOTAIR impairs the prognosis of papillary thyroid cancer via regulating cellular malignancy and epigenetically suppressing DLX1
Feng-Chih Kuo, Yu-Ting Wang, Chia-Hsin Liu, Yao-Feng Li, Chieh-Hua Lu, Sheng-Chiang Su, Jhih-Syuan Liu, Peng-Fei Li, Chia-Luen Huang, Li-Ju Ho, Chien-Ming Lin, Chien-Hsing Lee
The metastatic capacity of high-grade serous ovarian cancer cells changes along disease progression: inhibition by mifepristone
Sabrina J. Ritch, Abu Shadat M. Noman, Alicia A. Goyeneche, Carlos M. Telleria
Lyve-1 deficiency enhances the hepatic immune microenvironment entailing altered susceptibility to melanoma liver metastasis
Anna Sophia Jauch, Sebastian A. Wohlfeil, Céline Weller, Bianca Dietsch, Verena Häfele, Ana Stojanovic, Maximilian Kittel, Hendrik Nolte, Adelheid Cerwenka, Michael Neumaier, Kai Schledzewski, Carsten Sticht, Philipp-Sebastian Reiners-Koch, Sergij Goerdt, Cyrill Géraud
Ursolic acid: a natural modulator of signaling networks in different cancers
Sameen Zafar, Khushbukhat Khan, Amna Hafeez, Muhammad Irfan, Muhammad Armaghan, Anees ur Rahman, Eda Sönmez Gürer, Javad Sharifi-Rad, Monica Butnariu, Iulia-Cristina Bagiu, Radu Vasile Bagiu
Transcriptomic landscape of TIMP3 oncosuppressor activity in thyroid carcinoma
M. Mazzoni, K. Todoerti, L. Agnelli, E. Minna, S. Pagliardini, T. Di Marco, M. G. Borrello, A. Neri, A. Greco
Clinical potential of PD-1/PD-L1 blockade therapy for renal cell carcinoma (RCC): a rapidly evolving strategy
Mohammadsaleh Jahangir, Omid Yazdani, Mohammad Saeed Kahrizi, Sara Soltanzadeh, Hamidreza Javididashtbayaz, Azam Mivefroshan, Saba Ilkhani, Romina Esbati
Regulation of mitochondrial complex III activity and assembly by TRAP1 in cancer cells
Danilo Swann Matassa, Daniela Criscuolo, Rosario Avolio, Ilenia Agliarulo, Daniela Sarnataro, Consiglia Pacelli, Rosella Scrima, Alessandra Colamatteo, Giuseppe Matarese, Nazzareno Capitanio, Matteo Landriscina, Franca Esposito
Re-evaluation of the myoepithelial cells roles in the breast cancer progression
Anwar Shams
Oleic acid from cancer-associated fibroblast promotes cancer cell stemness by stearoyl-CoA desaturase under glucose-deficient condition
Sung-Hyun Hwang, Yeseul Yang, Jae-Ha Jung, Yongbaek Kim
Gaseous nitric oxide tumor ablation induces an anti-tumor abscopal effect
Hila Confino, Frederick M. Dirbas, Matan Goldshtein, Shay Yarkoni, Rinat Kalaora, Meital Hatan, Shani Puyesky, Yakir Levi, Lidor Malka, Matt Johnson, Selena Chaisson, Jedidiah M. Monson, Amir Avniel, Steve Lisi, David Greenberg, Ido Wolf
Retraction Note: Circ_002117 binds to microRNA-370 and promotes endoplasmic reticulum stress-induced apoptosis in gastric cancer
Nan Zhou, Hui Qiao, Miaomiao Zeng, Lei Yang, Yongning Zhou, Quanlin Guan
Natural essential oils as a new therapeutic tool in colorectal cancer
Stefania Garzoli, Pedro Alarcón-Zapata, Gulnaz Seitimova, Barbara Alarcón-Zapata, Miquel Martorell, Farukh Sharopov, Patrick Valere Tsouh Fokou, Darline Dize, Lauve Rachel Tchokouaha Yamthe, Francisco Les, Guillermo Cásedas, Víctor López, Marcello Iriti, Javad Sharifi Rad, Eda Sönmez Gürer, Daniela Calina, Raffaele Pezzani, Sara Vitalini
Retraction Note: LncRNA TUBA4B functions as a competitive endogenous RNA to inhibit gastric cancer progression by elevating PTEN via sponging miR-214 and miR-216a/b
Jianbo Guo, Yan Li, He Duan, Lu Yuan
Retraction Note: Knockdown of circRNA_0007534 suppresses the tumorigenesis of cervical cancer via miR-206/GREM1 axis
Qiang Sun, Xiangying Qi, Wenyan Zhang, Xiaoyu Li
Retraction Note: LINC01089 functions as a ceRNA for miR-152-3p to inhibit non‐small lung cancer progression through regulating PTEN
Huixian Zhang, Hao Zhang, Xingya Li, Siyuan Huang, Qianqian Guo, Di Geng
Cell senescence-associated genes predict the malignant characteristics of glioblastoma
Chenyang Tan, Yan Wei, Xuan Ding, Chao Han, Zhongzheng Sun, Chengwei Wang
Emerging roles and mechanisms of miR-206 in human disorders: a comprehensive review
Sheyda Khalilian, Seyedeh Zahra Hosseini Imani, Soudeh Ghafouri-Fard
Membrane protein trafficking in the anti-tumor immune response: work of endosomal-lysosomal system
Yan Jin, Zhifeng Deng, Ting Zhu
Mass spectrometry imaging in gynecological cancers: the best is yet to come
Dagmara Pietkiewicz, Szymon Plewa, Mikołaj Zaborowski, Timothy J. Garrett, Eliza Matuszewska, Zenon J. Kokot, Jan Matysiak
Increased expression of miR-194-5p through the circPVRL3/miR-194-5p/SOCS2 axis promotes proliferation and metastasis in pancreatic ductal adenocarcinoma by activating the PI3K/AKT signaling pathway
Bojing Chi, Yao Zheng, Fuming Xie, Wen Fu, Xianxing Wang, Jianyou Gu, Jiali Yang, Jingyang Yin, Lei Cai, Peng Tang, Jianbo Li, Shixiang Guo, Huaizhi Wang
Transition of amyloid/mutant p53 from tumor suppressor to an oncogene and therapeutic approaches to ameliorate metastasis and cancer stemness
Shinjinee Sengupta, Shaikh Maryam Ghufran, Aqsa Khan, Subhrajit Biswas, Susanta Roychoudhury
Therapeutic effect of a MUC1-specific monoclonal antibody-drug conjugates against pancreatic cancer model
Guang Wu, Lan Li, Mengnan Liu, Chunyan Chen, Guangze Wang, Zewei Jiang, Yaqian Qin, Licai He, Hongzhi Li, Jiawei Cao, Haihua Gu
Establishment and characterization of a new intrahepatic cholangiocarcinoma cell line derived from a Chinese patient
Xin Miao, Jinjing Hu, Changpeng Chai, Huan Tang, Zhenjie Zhao, Wei Luo, Wence Zhou, Hao Xu
Rise of the natural red pigment ‘prodigiosin’ as an immunomodulator in cancer
Mohammed Moustapha Anwar, Chris Albanese, Nadia M. Hamdy, Ahmed S. Sultan
Interactions of melatonin with various signaling pathways: implications for cancer therapy
Ainaz Mihanfar, Bahman Yousefi, Bita Azizzadeh, Maryam Majidinia
Targeting hyaluronic acid synthase-3 (HAS3) for the treatment of advanced renal cell carcinoma
Jiaojiao Wang, Andre R. Jordan, Huabin Zhu, Sarrah L. Hasanali, Eric Thomas, Soum D. Lokeshwar, Daley S. Morera, Sung Alexander, Joseph McDaniels, Anuj Sharma, Karina Aguilar, Semih Sarcan, Tianyi Zhu, Mark S. Soloway, Martha K. Terris, Muthusamy Thangaraju, Luis E. Lopez, Vinata B. Lokeshwar
Knock down of TIMP-2 by siRNA and CRISPR/Cas9 mediates diverse cellular reprogramming of metastasis and chemosensitivity in ovarian cancer
Ruth M. Escalona, Simon Chu, Elif Kadife, Jason K. Kelly, George Kannourakis, Jock K. Findlay, Nuzhat Ahmed
Genetic profiling of different phenotypic subsets of breast cancer stem cells (BCSCs) in breast cancer patients
Abdel-Rahman N. Zekri, Abeer Bahnassy, Magda Mourad, Ibrahim Malash, Ola Ahmed, Mona S. Abdellateif