Ausgabe 1/2016
Inhalt (91 Artikel)
Quince peel polyphenolic extract blocks human colon adenocarcinoma LS174 cell growth and potentiates 5-fluorouracil efficacy
Ichrak Riahi-Chebbi, Meriam Haoues, Makram Essafi, Ons Zakraoui, Sami Fattouch, Habib Karoui, Khadija Essafi-Benkhadir
RETRACTED ARTICLE: Mutation pattern is an influential factor on functional mutation rates in cancer
Chuance Du, Xiaoyuan Wu, Jia Li
Cytotoxic and apoptogenic effect of hypericin, the bioactive component of Hypericum perforatum on the MCF-7 human breast cancer cell line
Seyed Abbas Mirmalek, Mohammad Amin Azizi, Ehsan Jangholi, Soheila Yadollah-Damavandi, Mohammad Amin Javidi, Yekta Parsa, Tina Parsa, Seyed Alireza Salimi-Tabatabaee, Hossein Ghasemzadeh kolagar, Reza Alizadeh-Navaei
Characterisation of bioenergetic pathways and related regulators by multiple assays in human tumour cells
A. Jeney, Z. Hujber, N. Szoboszlai, A. Fullár, J. Oláh, É. Pap, Á. Márk, Cs. Kriston, J. Kralovánszky, I. Kovalszky, K. Vékey, A. Sebestyén
Heat shock protein 27 downstream of P38-PI3K/Akt signaling antagonizes melatonin-induced apoptosis of SGC-7901 gastric cancer cells
Wenjie Deng, Yujie Zhang, Luo Gu, Jie Cui, Biao Duan, Yueyuan Wang, Jun Du
Antibiotics inhibit sphere-forming ability in suspension culture
Sébastien Relier, Laura Yazdani, Oualid Ayad, Armelle Choquet, Jean-François Bourgaux, Michel Prudhomme, Julie Pannequin, Françoise Macari, Alexandre David
Effects of the lifestyle habits in breast cancer transcriptional regulation
Marco Allán Pérez-Solis, Guadalupe Maya-Nuñez, Patricia Casas-González, Aleida Olivares, Arturo Aguilar-Rojas
ELF5 and DOK7 regulation in anti-estrogen treated cells and tumors
Lily M. Fitzgerald, Eva P. Browne, Kevin D. Christie, Elizabeth C. Punska, Leo O. Simmons, Kristin E. Williams, Brian T. Pentecost, Rahul M. Jawale, Christopher N. Otis, Kathleen F. Arcaro
Inhibition of glycolytic enzyme hexokinase II (HK2) suppresses lung tumor growth
Huanan Wang, Lei Wang, Yingjie Zhang, Ji Wang, Yibin Deng, Degui Lin
Paclitaxel and the dietary flavonoid fisetin: a synergistic combination that induces mitotic catastrophe and autophagic cell death in A549 non-small cell lung cancer cells
Anna Klimaszewska-Wisniewska, Marta Halas-Wisniewska, Tadeusz Tadrowski, Maciej Gagat, Dariusz Grzanka, Alina Grzanka
Solamargine triggers cellular necrosis selectively in different types of human melanoma cancer cells through extrinsic lysosomal mitochondrial death pathway
Sana S. Al Sinani, Elsadig A. Eltayeb, Brenda L. Coomber, Sirin A. Adham
MicroRNA-410-5p as a potential serum biomarker for the diagnosis of prostate cancer
Jiaqi Wang, Huamao Ye, Dandan Zhang, Yijun Hu, Xiya Yu, Long Wang, Changjing Zuo, Yongwei Yu, Guixia Xu, Shanrong Liu
Tumor suppressor genes and their underlying interactions in paclitaxel resistance in cancer therapy
Jia-Hui Xu, Shi-Lian Hu, Guo-Dong Shen, Gan Shen
Non-DHFR-mediated effects of methotrexate in osteosarcoma cell lines: epigenetic alterations and enhanced cell differentiation
Martin Sramek, Jakub Neradil, Jaroslav Sterba, Renata Veselska
Decreased expression of Sushi Domain Containing 2 correlates to progressive features in patients with hepatocellular carcinoma
Xin-rui Liu, Cui-xia Cai, Li-min Luo, Wen-Ling Zheng, Rong Shi, Jun Zeng, You-qin Xu, Min Wei, Wen-li Ma
Identification of biological targets of therapeutic intervention for clear cell renal cell carcinoma based on bioinformatics approach
Yongsheng Chen, Lichen Teng, Wenhua Liu, Yan Cao, Dexin Ding, Wentao Wang, Hui Chen, Changfu Li, Ruihua An
Transcription factor CCAAT/enhancer binding protein alpha up-regulates microRNA let-7a-1 in lung cancer cells by direct binding
Yani Lin, Jian Zhao, Xiaoyan Hu, Lina Wang, Liming Liang, Weiwen Chen
Evidence that phospholipase C is involved in the antitumour action of NSC768313, a new thieno[2,3-b]pyridine derivative
Jóhannes Reynisson, Jagdish K. Jaiswal, David Barker, Stacey A. N. D’mello, William A. Denny, Bruce C. Baguley, Euphemia Y. Leung
Suppression of Spry4 enhances cancer stem cell properties of human MDA-MB-231 breast carcinoma cells
Hongyu Jing, Lucy Liaw, Robert Friesel, Calvin Vary, Shucheng Hua, Xuehui Yang
Knockdown of PSCA induces EMT and decreases metastatic potentials of the human prostate cancer DU145 cells
Ran Kang, Shankun Zhao, Luhao Liu, Futian Li, Ermao Li, Lianmin Luo, Lihua Xu, ShawPong Wan, Zhigang Zhao
MiR-519d facilitates the progression and metastasis of cervical cancer through direct targeting Smad7
Jue-Yu Zhou, Si-Rong Zheng, Jie Liu, Rong Shi, Hai-Lang Yu, Min Wei
Time course analysis based on gene expression profile and identification of target molecules for colorectal cancer
Guoting Chen, Ning Han, Guofeng Li, Xin Li, Guang Li, Zengchun Li, Qinchuan Li
Analysing the mutational status of adenomatous polyposis coli (APC) gene in breast cancer
Ya-Sian Chang, Chien-Yu Lin, Shu-Fen Yang, Cheng-Mao Ho, Jan-Gowth Chang
The voltage gated Ca2+-channel Cav3.2 and therapeutic responses in breast cancer
Elena Pera, Elke Kaemmerer, Michael J. G. Milevskiy, Kunsala T. D. S. Yapa, Jake S. O’Donnell, Melissa A. Brown, Fiona Simpson, Amelia A. Peters, Sarah J. Roberts-Thomson, Gregory R. Monteith
Stress-induced endocytosis and degradation of epidermal growth factor receptor are two independent processes
Ke Peng, Qian Dai, Jing Wei, Genbao Shao, Aiqin Sun, Wannian Yang, Qiong Lin
Weight loss reduces basal-like breast cancer through kinome reprogramming
Yuanyuan Qin, Sneha Sundaram, Luma Essaid, Xin Chen, Samantha M. Miller, Feng Yan, David B. Darr, Joseph A. Galanko, Stephanie A. Montgomery, Michael B. Major, Gary L. Johnson, Melissa A. Troester, Liza Makowski
The BH3 mimetic drug ABT-737 induces apoptosis and acts synergistically with chemotherapeutic drugs in thyroid carcinoma cells
Martina Broecker-Preuss, Nina Becher-Boveleth, Stefan Müller, Klaus Mann
Basigin-2 upregulated by receptor activator of NF-κB ligand enhances lung cancer-induced osteolytic lesions
Cheng-Gong Liao, Li Yao, Wei Xie, Lili Liu, Sheng-Da Wu, Ning Lu, Jian-Guo Huang, Ling-Min Kong, He-Long Zhang
SOX17 increases the cisplatin sensitivity of an endometrial cancer cell line
Yongli Zhang, FeiZhou Jiang, Wei Bao, Huilin Zhang, XiaoYing He, Huihui Wang, Xiaoping Wan
MiR-1244 sensitizes the resistance of non-small cell lung cancer A549 cell to cisplatin
Weili Li, Wenzhe Wang, Mingjian Ding, Xiaoliang Zheng, Shenglin Ma, Xiaoju Wang
The histone deacetylase inhibitor PCI-24781 as a putative radiosensitizer in pediatric glioblastoma cell lines
Pamela Viani de Andrade, Augusto Faria Andrade, Rosane Gomes de Paula Queiroz, Carlos Alberto Scrideli, Luiz Gonzaga Tone, Elvis Terci Valera
LIN28B is highly expressed in atypical teratoid/rhabdoid tumor (AT/RT) and suppressed through the restoration of SMARCB1
Seung Ah Choi, Seung-Ki Kim, Ji Yeoun Lee, Kyu-Chang Wang, Chanhee Lee, Ji Hoon Phi
Hypoxia-induced modulation of PTEN activity and EMT phenotypes in lung cancers
Takashi Kohnoh, Naozumi Hashimoto, Akira Ando, Koji Sakamoto, Shinichi Miyazaki, Daisuke Aoyama, Masaaki Kusunose, Motohiro Kimura, Norihito Omote, Kazuyoshi Imaizumi, Tsutomu Kawabe, Yoshinori Hasegawa
Combined EGFR- and notch inhibition display additive inhibitory effect on glioblastoma cell viability and glioblastoma-induced endothelial cell sprouting in vitro
Mikkel Staberg, Signe Regner Michaelsen, Louise Stobbe Olsen, Mette Kjølhede Nedergaard, Mette Villingshøj, Marie-Thérése Stockhausen, Petra Hamerlik, Hans Skovgaard Poulsen
A humanized anti-CD26 monoclonal antibody inhibits cell growth of malignant mesothelioma via retarded G2/M cell cycle transition
Mutsumi Hayashi, Hiroko Madokoro, Koji Yamada, Hiroko Nishida, Chikao Morimoto, Michiie Sakamoto, Taketo Yamada
Temozolomide promotes genomic and phenotypic changes in glioblastoma cells
Aleksei A. Stepanenko, Svitlana V. Andreieva, Kateryna V. Korets, Dmytro O. Mykytenko, Vladimir P. Baklaushev, Nataliya L. Huleyuk, Oksana A. Kovalova, Kateryna V. Kotsarenko, Vladimir P. Chekhonin, Yegor S. Vassetzky, Stanislav S. Avdieiev, Vladimir V. Dmitrenko
Lyn, a tyrosine kinase closely linked to the differentiation status of primary acute myeloid leukemia blasts, associates with negative regulation of all-trans retinoic acid (ATRA) and dihydroxyvitamin D3 (VD3)-induced HL-60 cells differentiation
Noriyoshi Iriyama, Bo Yuan, Yoshihiro Hatta, Norio Takagi, Masami Takei
Erratum to: Inhibition of glycolytic enzyme hexokinase II (HK2) suppresses lung tumor growth
Huanan Wang, Lei Wang, Yingjie Zhang, Ji Wang, Yibin Deng, Degui Lin
Induction of G1-phase cell cycle arrest and apoptosis pathway in MDA-MB-231 human breast cancer cells by sulfated polysaccharide extracted from Laurencia papillosa
Hossam Murad, Mohammad Hawat, Adnan Ekhtiar, Abdulmunim AlJapawe, Assef Abbas, Hussein Darwish, Oula Sbenati, Ahmed Ghannam
Retraction Note: Psoriasin (S100A7) is a novel biomarker for lung squamous cell carcinoma in humans
Guijuan Liu, Qiang Wu, Guilan Liu, Xueying Song, Jihong Zhang
Comprehensive characterization of the patient-derived xenograft and the paralleled primary hepatocellular carcinoma cell line
Phyllis F. Y. Cheung, Chi Wai Yip, Linda W. C. Ng, Kwok Wai Lo, Chit Chow, Kui Fat Chan, Tan To Cheung, Siu Tim Cheung
MicroRNA-210 induces apoptosis in colorectal cancer via induction of reactive oxygen
Katrin E. Tagscherer, Anne Fassl, Tabea Sinkovic, Jutta Richter, Sabrina Schecher, Stephan Macher-Goeppinger, Wilfried Roth
Failure of a patient-derived xenograft for brain tumor model prepared by implantation of tissue fragments
Kyung-Min Kim, Jin-Kyoung Shim, Jong Hee Chang, Ji-Hyun Lee, Se-Hoon Kim, Junjeong Choi, Junseong Park, Eui-Hyun Kim, Sun Ho Kim, Yong-Min Huh, Su-Jae Lee, Jae-Ho Cheong, Seok-Gu Kang
Influence of TP53 and CDH1 genes in hepatocellular cancer spheroid formation and culture: a model system to understand cancer cell growth mechanics
Joseph M. Pomo, Robert M. Taylor, Rama R. Gullapalli
In vivo enhancement of the MAGE-specific cellular immune response by a recombinant MAGE1-MAGE3-TBHSP70 tumor vaccine
Wang Junwei, Zhan Xiumin, Ye Jing, Yang Shoujing, Li Zengshan
The availability of the embryonic TGF-β protein Nodal is dynamically regulated during glioblastoma multiforme tumorigenesis
Maria Cecília Oliveira-Nunes, Suzana Assad Kahn, Ana Luiza de Oliveira Barbeitas, Tania Cristina Leite de Sampaio e Spohr, Luiz Gustavo Feijó Dubois, Grasiella Maria Ventura Matioszek, William Querido, Loraine Campanati, José Marques de Brito Neto, Flavia Regina Souza Lima, Vivaldo Moura-Neto, Katia Carneiro
Prognostic value of CD44 expression in patients with hepatocellular carcinoma: meta-analysis
Yangkun Luo, Yan Tan
Zinc induces epithelial to mesenchymal transition in human lung cancer H460 cells via superoxide anion-dependent mechanism
Chuanpit Ninsontia, Preeyaporn Plaimee Phiboonchaiyanan, Pithi Chanvorachote
Survivin: a unique target for tumor therapy
Himani Garg, Prerna Suri, Jagdish C. Gupta, G. P. Talwar, Shweta Dubey
Involvement of human chorionic gonadotropin in regulating vasculogenic mimicry and hypoxia-inducible factor-1α expression in ovarian cancer cells
Min Su, Xiangxiang Xu, Weiwei Wei, Sainan Gao, Xiaoying Wang, Caoyi Chen, Yuquan Zhang
A microalga, Euglena tuba induces apoptosis and suppresses metastasis in human lung and breast carcinoma cells through ROS-mediated regulation of MAPKs
Sourav Panja, Nikhil Baban Ghate, Nripendranath Mandal
Laparoscopic spleen-preserving hilar lymph node dissection through pre-pancreatic and retro-pancreatic approach in patients with gastric cancer
Liansheng Zheng, Ce Zhang, Da Wang, Qi Xue, Xiaoping Liu, Ke-Jian Zhou, Hao Liu, Guoxin Li
PARG deficiency is neither synthetic lethal with BRCA1 nor PTEN deficiency
Aurélia Noll, Giuditta Illuzzi, Jean-Christophe Amé, Françoise Dantzer, Valérie Schreiber
Positive effect of HPV status on prognostic value of blood lymphocyte-to-monocyte ratio in advanced cervical carcinoma
Si-wei Li, Wenxin Yuan, Bo Zhao, Zhuo-kai He, Xiang Guo, Wei-xiong Xia, Li-hua Xu
Expression and diagnostic value of CCT3 and IQGAP3 in hepatocellular carcinoma
E-Na Qian, Shuang-Yin Han, Song-Ze Ding, Xun Lv
Calreticulin mediates an invasive breast cancer phenotype through the transcriptional dysregulation of p53 and MAPK pathways
Mohammadreza Zamanian, Lama Abdel Qader Hamadneh, Abhi Veerakumarasivam, Sabariah Abdul Rahman, Shamarina Shohaimi, Rozita Rosli
Oridonin inhibits pancreatic cancer cell migration and epithelial-mesenchymal transition by suppressing Wnt/β-catenin signaling pathway
Qian-Qian Liu, Ke Chen, Qiao Ye, Xiao-Hua Jiang, Yun-Wei Sun
Topoisomerase IIβ mediates the resistance of glioblastoma stem cells to replication stress-inducing drugs
Saša Kenig, Valentina Faoro, Evgenia Bourkoula, Neža Podergajs, Tamara Ius, Marco Vindigni, Miran Skrap, Tamara Lah, Daniela Cesselli, Paola Storici, Alessandro Vindigni
High EZH2 expression is correlated to metastatic disease in pediatric soft tissue sarcomas
Maria Ramaglia, Velia D’Angelo, Adriana Iannotta, Daniela Di Pinto, Elvira Pota, Maria Carmen Affinita, Vittoria Donofrio, Maria Elena Errico, Angela Lombardi, Cristiana Indolfi, Fiorina Casale, Michele Caraglia
Endogenous electromagnetic forces emissions during cell respiration as additional factor in cancer origin
Abraham A. Embi
PADI2 gene confers susceptibility to breast cancer and plays tumorigenic role via ACSL4, BINC3 and CA9 signaling
Huifeng Wang, Bing Xu, Xiaoqian Zhang, Yabing Zheng, Yan Zhao, Xiaotian Chang
Resistance to receptor tyrosine kinase inhibitors in solid tumors: can we improve the cancer fighting strategy by blocking autophagy?
Sanja Aveic, Gian Paolo Tonini
miRNA-135a promotes hepatocellular carcinoma cell migration and invasion by targeting forkhead box O1
Yue-Bin Zeng, Xing-Hua Liang, Guang-Xian Zhang, Nan Jiang, Tong Zhang, Jian-Ying Huang, Lei Zhang, Xian-Cheng Zeng
MiR-20a-5p represses multi-drug resistance in osteosarcoma by targeting the KIF26B gene
Youguang Pu, Qiyi Yi, Fangfang Zhao, Haiyan Wang, Wenjing Cai, Shanbao Cai
MiR-145 functions as a tumor suppressor via regulating angiopoietin-2 in pancreatic cancer cells
Hao Wang, Cheng Hang, Xi-Long Ou, Jin-Shan Nie, Yi-Tao Ding, Shi-Gui Xue, Hua Gao, Jian-Xin Zhu
Schedule-dependent increased efficiency of pemetrexed-ionizing radiation combination therapy elicits a differential DNA damage response in lung cancer cells
Patrick Dorn, Colin Charles Tièche, Ren-Wang Peng, Laurène Froment, Ralph Alexander Schmid, Thomas Michael Marti
MicroRNA-23a regulates epithelial-to-mesenchymal transition in endometrial endometrioid adenocarcinoma by targeting SMAD3
Ping Liu, Chao Wang, Chengbin Ma, Qiongwei Wu, Wenying Zhang, Guoying Lao
Molecular mechanism leading to SAHA-induced autophagy in tumor cells: evidence for a p53-dependent pathway
Leopold F. Fröhlich, Maria Mrakovcic, Claudia Smole, Kurt Zatloukal
CD147 promotes cell motility via upregulation of p190-B RhoGAP in hepatocellular carcinoma
Ruo Chen, Shi-Jie Wang, Yang Zhang, Rong Hou, Jian-Li Jiang, Hong-Yong Cui
Selected polyphenols potentiate the apoptotic efficacy of glycolytic inhibitors in human acute myeloid leukemia cell lines. Regulation by protein kinase activities
Elena de Blas, María Cristina Estañ, María del Carmen Gómez de Frutos, Javier Ramos, María del Carmen Boyano-Adánez, Patricio Aller
Robo3A and Robo3B expression is regulated via alternative promoters and mRNA stability
Anke Ruedel, Mandy Schott, Thomas Schubert, Anja Katrin Bosserhoff
Altering bioelectricity on inhibition of human breast cancer cells
Seher Berzingi, Mackenzie Newman, Han-Gang Yu
RETRACTED ARTICLE: Long noncoding RNA ANRIL is activated by hypoxia-inducible factor-1α and promotes osteosarcoma cell invasion and suppresses cell apoptosis upon hypoxia
Xiaokang Wei, Chuanshun Wang, Chunhui Ma, Wei Sun, Haoqing Li, Zhendong Cai
KIAA0101, a target gene of miR-429, enhances migration and chemoresistance of epithelial ovarian cancer cells
Hong Chen, Bairong Xia, Tianbo Liu, Mei Lin, Ge Lou
Success of tumorsphere isolation from WHO grade IV gliomas does not correlate with the weight of fresh tumor specimens: an immunohistochemical characterization of tumorsphere differentiation
Kyoung Su Sung, Jin-Kyoung Shim, Ji-Hyun Lee, Se Hoon Kim, Sohee Park, Tae-Hoon Roh, Ju Hyung Moon, Eui-Hyun Kim, Sun Ho Kim, Su Jae Lee, Yong Min Huh, Seok-Gu Kang, Jong Hee Chang
Relationship between TRAF6 and deterioration of HCC: an immunohistochemical and in vitro study
Jian-jun Li, Jie Luo, Jing-ning Lu, Xiao-na Liang, Yi-huan Luo, Yong-ru Liu, Jie Yang, Hua Ding, Gui-hui Qin, Li-hua Yang, Yi-wu Dang, Hong Yang, Gang Chen
Bone morphogenetic protein 2 (BMP2) induces growth suppression and enhances chemosensitivity of human colon cancer cells
Radhakrishnan Vishnubalaji, Shijun Yue, Musaad Alfayez, Moustapha Kassem, Fei-Fei Liu, Abdullah Aldahmash, Nehad M. Alajez
Cytologic studies of the fallopian tube in patients undergoing salpingo-oophorectomy
Hao Chen, Robert Klein, Stacy Arnold, Setsuko Chambers, Wenxin Zheng
Expression of microtubule-associated protein TPX2 in human gastric carcinoma and its prognostic significance
Cuijie Shao, Changsheng Duan, Jiani Wang, Shunlian Luan, Yong Gao, Dan Jin, Deqiang Wang, Yuming Li, Lihua Xu
The chimeric multi-domain proteins mediating specific DNA transfer for hepatocellular carcinoma treatment
Encheng Yang, Xiao Li, Ningyi Jin
Long non-coding RNA DBCCR1-003 regulate the expression of DBCCR1 via DNMT1 in bladder cancer
Defeng Qi, Jinhui Li, Biao Que, Jialin Su, Mengxi Li, Chaofeng Zhang, Mei Yang, Guoren Zhou, Weidong Ji
The zebrafish as a model for studying neuroblastoma
Diana Corallo, Simona Candiani, Michela Ori, Sanja Aveic, Gian Paolo Tonini
Retraction Note to: Diagnosis, classification and grading of canine mammary tumours as a model to study human breast cancer: an Clinico-Cytohistopathological study with environmental factors influencing public health and medicine
Radmehr Shafiee, Javad Javanbakh, Nahid Atyabi, Pegah Kheradmand, Danial Kheradmand, Alimohammad Bahrami, Hasti Daraei, Farshid Khadivar
Retraction Note: Down-regulation of miR-133a and miR-539 are associated with unfavorable prognosis in patients suffering from osteosarcoma
Alireza Mirghasemi, Afshin Taheriazam, Seyyed Hasan Karbasy, Ali Torkaman, Mohammadreza Shakeri, Emad Yahaghi, Aram Mokarizadeh
RETRACTED ARTICLE: Overexpression of A613T and G462T variants of DNA polymerase β weakens chemotherapy sensitivity in esophageal cancer cell lines
Yuanyuan Wang, Xiaonan Chen, Qianqian Sun, Wenqiao Zang, Min Li, Ziming Dong, Guoqiang Zhao
Alpha-synuclein contributes to malignant progression of human meningioma via the Akt/mTOR pathway
Yiqin Ge, Kan Xu
Simultaneous dual targeting of Par-4 and G6PD: a promising new approach in cancer therapy? Quintessence of a literature review on survival requirements of tumor cells
Ingeborg Elisabeth Cernaj
Cell division cycle 7-kinase inhibitor PHA-767491 hydrochloride suppresses glioblastoma growth and invasiveness
Zubeyde Erbayraktar, Begum Alural, Resat Serhat Erbayraktar, Erdogan Pekcan Erkan
Comprehensive analysis of the long noncoding RNA HOXA11-AS gene interaction regulatory network in NSCLC cells
Yu Zhang, Rong-quan He, Yi-wu Dang, Xiu-ling Zhang, Xiao Wang, Su-ning Huang, Wen-ting Huang, Meng-tong Jiang, Xiao-ning Gan, You Xie, Ping Li, Dian-zhong Luo, Gang Chen, Ting-qing Gan
Inhibition of integrin β3, a binding partner of kallistatin, leads to reduced viability, invasion and proliferation in NCI-H446 cells
Guoquan Wang, Xiao Wang, Xiaoping Huang, Huiyong Yang, Suqiu Pang, Xiaolan Xie, Shulan Zeng, Junsheng Lin, Yong Diao
Autophagy induced by a sulphamoylated estrone analogue contributes to its cytotoxic effect on breast cancer cells
Marcel Verwey, Elsie M. Nolte, Anna M. Joubert, Anne E. Theron