Ausgabe Sonderheft 3/2004
Global Arthritis Research Network (GARN): 4th World Congress on Arthritis in Montreal
Inhalt (104 Artikel)
Health needs assessment of musculoskeletal conditions: an international bone and joint burden of disease study
N Khaltaev, B Pfleger, AD Woolf, K Åkesson, JM Hazes, D Symmons
Genetics of osteoarthritis
J Loughlin, A Ferreira, B Dowling, L Southam, Z Mustafa, T Forster, K Chapman
Genome-wide single nucleotide polymorphism analyses on rheumatoid arthritis
K Yamamoto, A Suzuki, S Tokuhiro, Y Kochi, R Yamada
Rheumatoid arthritis: a heterogeneous disease evaluated by DNA-microarray technology
PV Kasperkovitz, T Timmer, T Smeets, PP Tak, TWJ Huizinga, GS Firestein, F Rustenburg, TCTM van der Pouw Kraan, M Fero, CL Verweij
Hyper-ERAD: a novel pathomechanism for rheumatoid arthritis
T Nakajima, N Yagishita, S Yamasaki, K Tsuchimochi, T Amano, A Fukamizu, I Maruyama, K Nishioka
Is leptin the link between obesity and osteoarthritis?
P Pottie, N Presle, H Dumond, B Terlain, D Mainard, D Leuille, P Netter
Regulation of eicosanoid synthesis by leptin
P Mancuso, HH Mehta, C Canetti, M Peters-Golden, BJ Roessler, LJ Crofford
Transcriptional regulation of the mPGES-1 gene in primary cultured articular chondrocytes
P Bausero, C Salvat, V Meynier de Salinelles, A Pigenet, M Raymondjean, F Berenbaum
ALXR, a common GPCR gateway for antiinflammatory and/or proinflammatory cell activation: relevance of selective kinase and phospholipase signaling by uteroglobin, lipoxin A4and serum amyloid A in ALXR-mediated chemotaxis
G Antico, S Sodin-Semrl, J Varga, L Miele, S Fiore
Regulation of neutrophil trafficking by the lipid mediators of inflammation
S Marleau, J Lefebvre, H El Iman, C Bélanger, P Borgeat
The nonsense allele oblivious reveals a sensor of di-acylglycerides acting in conjunction with TLR2 and TLR6
K Hoebe, K Tabeta, P Georgel, X Du, S Mudd, S Sovath, L Shamel, T Hartung, Ul Zähringer, B Beutler
An apoptotic signaling pathway activated by Nod1
J da Silva Correia, Y Miranda, N Austin-Brown, J Mathison, J Han, RJ Ulevitch
Post-transcriptional regulation of tumor necrosis factor alpha expression
S Brooks, W Rigby
A proinflammatory chemokine, CCL3, sensitizes the heat-gated and capsaicin-gated ion channel, TRPV1
N Zhang, S Inan, A Cowan, AD Guler, R Sun, J Wang, TJ Rogers, M Caterina, JJ Oppenheim
Cellular-based immune modulation in arthritis
REM Toes, J van Bilsen, H van Dongen, L Lard, EIH van der Voort, D Elferink, A Bakker, A Miltenburg, FC Breedveld, TH Huizinga, RRP de Vries
Regulating innate immune response cytokines in synovitis
IB McInnes, D Xu, JA Gracie, X Wei, FY Liew
Galectin-3 in osteoarthritis: from a protective to a destructive role
C Boileau, J Martel-Pelletier, M Guévremont, J-P Pelletier, F Poirier, P Reboul
Angiogenesis and arthritis: a potential therapeutic target?
J Grosjean, B Sivakumar, E Paleolog
The αvβ3 integrin as a therapeutic target for inhibition of bone resorption
SJ Dixon, J Bashutski, M-L Rütz, HA Goldberg, SM Sims, A Gramoun, S Shorey, M Manolson, JN Heersche, H Zhang, J Suzich, S-Y Mao
Issues in structure-modifying osteoarthritis drug development: new insights regarding radiographic clinical trial methods
JF Beary, GA Cline
A 2-year evaluation of disease progression by quantitative magnetic resonance imaging in a large primary osteoarthritic patient population
J-P Raynauld, J Martel-Pelletier, M-J Berthiaume, G Beaudoin, F Labonté, DA Bloch, D Choquette, B Haraoui, RD Altman, M Hochberg, J Beary, G Cline, J Meyer, DJ Valent, J-P Pelletier
The use of imaging and biomarkers in the assessment and follow-up of arthritis
P Emery
Antibody-initiated organ injury: apoptosis, inflammation and fibrosis in neonatal lupus
JP Buyon, RM Clancy
Autoantibodies and cognitive impairment in systemic lupus erythematosus
C Kowal, L DeGiorgio, P Huerta, H Hetherington, B Volpe, B Diamond
Anti-DNA topoisomerase I autoantibodies bind directly to the cell surface of fibroblasts in patients with systemic sclerosis
J-L Senécal, J Hénault, M Tremblay, I Clément, Y Raymond
Mechanisms of autoimmunity in mice lacking the mer membrane tyrosine kinase
PL Cohen, Y Du, V Abraham, M Waldman, A Choudhury, A Vogelgesang, G Wittenburg
Natural antibodies and autoantibodies bind to injured tissues, activate complement and cause organ damage
GC Tsokos, S Fleming
Menopause and hormone replacement therapy: effects on the immune system, arthritis and bone
H Carlsten, H Forsblad D'Elia, M Erlandsson, U Islander
Adverse effects of rheumatoid arthritis on bone remodeling
SR Goldring, EM Gravallese
Pharmacokinetic–pharmacodynamic modeling considering spinal and peripheral actions of nonsteroidal antiinflammatory drugs to optimize the treatment of inflammation-induced pain
G Castañeda-Hernández, MI Ortiz, J Lozano-Cuenca, JE Torres-López, V Granados-Soto
Regulation of B-cell tolerance by complement C4
M Alimzhanov, T Imanishi-Kari, MC Carroll
Complement and autoimmunity: new insights into old questions
VM Holers, N Banda, DM Kraus, KA Kuhn, M Muggli, JM Thurman, WP Arend
Insights into systemic lupus erythematosus pathogenesis through blood global gene expression analysis
V Pascual, L Bennett, F Allantaz, E Arce, J Banchereau
Regulation of innate and adaptive immunity and autoimmunity by Toll-like receptor 9
AM Krieg
Molecular regulation of gene expression in chondrocytes by inflammatory mediators
MB Goldring, H Peng, K Ijiri, T Libermann, P Oettgen
Endothelin-1 induces extracellular matrix degradation via matrix metalloproteinases induction in human osteosarcoma cells
M Felx, F Shipkolye, M Isler, J Doyon, A Moreau, F Moldovan
Endothelin-1 in osteoarthritic chondrocytes triggers nitric oxide production and upregulates collagenase production
CA Manacu, J Martel-Pelletier, M Roy-Beaudry, J-P Pelletier, JC Fernandes, F Shipkolye, F Moldovan
Intracellular IL-1Ra exhibits unique antiinflammatory properties
WP Arend, N Banda, M Muggli, D Sheppard, C Guthridge, K Santopietro, D Bech-Otschir, W Dubiel
Oral treatment with PD-0200347, an α2δ ligand, reduces the development of experimental osteoarthritis by inhibiting the chondrocytes metalloproteases and inducible nitric oxide synthase gene expression and synthesis
C Boileau, J Martel-Pelletier, J Brunet, G Tardif, D Schrier, C Flory, M Boily, J-P Pelletier
Nonsteroidal antiinflammatory drug use may be protective to cartilage in osteoarthritis of the hip and knee
JE Pope, A Stevens, K McCrea, J Ouimet
Chondral defects: genetic contribution and relevance and associations with pain, age, body mass index, joint surface area, cartilage volume and radiographic features of osteoarthritis
G Jones, C Ding, G Zhai, F Scott, H Cooley, F Cicuttini
Quantitative measurements of articular cartilage by magnetic resonance imaging
LD Hall, J Burge, S Evans, R Poole
Elevated C-reactive protein levels in osteoarthritis are associated with local joint inflammation
AD Pearle, CR Scanzello, SS George, L Mandl, EF DiCarlo, MK Crow, TP Sculco
Influence of corticosteroids on C-reactive protein in patients with rheumatoid arthritis
E Mysler, C Psioni, P Tate, G Tate
Immune tolerance: DNA vaccine as strategy in autoimmune diseases
I Djilali Saiah
Differential induction of IL-1β and tumor necrosis factor by CD40 ligand or cellular contact with stimulated T cells depends on the degree of maturity of human monocytes
D Burger, N Molnarfi, L Gruaz, J-M Dayer
Protective role of interferon gamma in murine antigen-induced arthritis
M Hückel, I Irmler, J Simon, A Radbruch, A Scheffold, R Bräuer
Regulatory role of C5a anaphylatoxin on the Fcγ Rs effector system in immune complex-induced diseases
RE Schmidt, J Skokowa, SR Ali, W Kumar, N Shushakova, JE Gessner
Differential modulation of cysteinyl leukotriene receptor 1 and 2 expression by distinct Toll-like receptor agonists in monocyte-derived dendritic cells
M Rola-Pleszczynski, M Thivierge, J Stankova
RANK and RANKL expression in RA synovium and lymph nodes as markers of dendritic cell-T cell interactions
G Page, P Miossec
The potential role of adiponectin in driving arthritis
U Müller-Ladner, A Ehling, E Neumann, IH Tarner, H Herfarth, J Grifka, J Schölmerich, S Gay, A Schäffler
Leptin induces production of eicosanoids and proinflammatory cytokines in human synovial fibroblasts
LJ Crofford, HH Mehta, BJ Roessler, P Mancuso
Activation of peroxisome proliferator-activated receptor γ inhibits IL-1β-induced mPGES-1 expression in human synovial fibroblasts by interfering with Egr-1
S Cheng, H Afif, J Martel-Pelletier, J-P Pelletier, X Li, K Farrajota, M Lavigne, H Fahmi
15-Deoxy-Δ12,14-prostaglandin J2inhibits IL-1β-induced cyclooxygenase-2 expression in human synovial fibroblasts through a histone deacetylase-independent mechanism
K Farrajota, H Afif, J Martel-Pelletier, J-P Pelletier, X Li, S Cheng, M Lavigne, H Fahmi
A critical role for leukotriene B4 in K/BxN serum transfer arthritis pathogenesis
M Chen, BK Lam, KF Austen, Y Kanaoka, DM Lee
Clusterin, a potential pathophysiological actor in rheumatoid arthritis
V Devauchelle, M Breban, M Dougados, C Fournier, G Chiocchia
Systemic lupus erythematosus is characterized by faulty B-cell tolerance in the germinal centers
J Anolik, A Cappione, I Sanz
Interferon-induced gene expression in systemic lupus erythematosus reflects previous exposure to interferon alpha and is associated with increased disease activity and autoreactivity against RNA-binding proteins
KA Kirou, CY Lee, SS George, MK Crow
An open-label safety and efficacy study of an anti-CD20 antibody (rituximab, Rituxan) for anti-B-cell therapy in the treatment of systemic lupus erythematosus
RA Eisenberg, S Khan, J Stansberry, D Tsai, S Kolasinski, E Rieder, B Kotzin, RJ Looney, C Strieber, D Albert
Analysis of IgVH-specific, CXCR4-specific and CXR5-specific mRNA transcripts in individual peripheral blood B cells of patients with primary Sjögren's syndrome and normal healthy subjects
A Hansen, K Reiter, M Gosemann, T Ziprian, PE Lipsky, T Dörner
Lymphoid chemokine expression in Sjogren's syndrome: relationship with the lymphoid organization of the periductal inflammatory aggregates
F Barone, M Bombardieri, MC Blades, A Manzo, P Morgan, S Challacombe, G Valesini, C Pitzalis
Clinical classification of fibromyalgia according to disease progression
K Nishioka
Raynaud's phenomenon secondary to rheumatoid arthritis may be predictive of more erosive disease
JE Pope, J Al-beshri
The role of TLR4 and neutrophil expression in infection-triggered arthritis
X Zhang, M Glogauer, F Zhu, T Kim, B Chiu, RD Inman
Inhibition of complement activation: a novel mechanism for the protective effects of heparin in antiphospholipid antibody-induced pregnancy loss
G Girardi, P Redecha, J Salmon
Advanced glycation endproducts in the development of osteoarthritis
J DeGroot, RA Bank, JWJ Bijlsma, JM TeKoppele, N Verzijl, FPJG Lafeber
New emerging roles of transcription factor Pitx1 and Reg growth factors in osteoarthritis pathogenesis
A Moreau, DS Wang, S Jacques, C Chassaing, V Landreville, J Martel-Pelletier, J Fernandes
Differential gene expression and regulation of the bone morphogenic protein antagonists follistatin and gremlin in normal and osteoarthritic human chondrocytes and synovial fibroblasts
G Tardif, D Hum, J-P Pelletier, C Boileau, P Ranger, J Martel-Pelletier
Tumor necrosis factor alpha downregulates bone morphogenetic protein expression and matrix macromolecule synthesis in articular cartilage
K Bobacz, S Hayer, G Kollias, JS Smolen, G Schett
Arthritis induces lymphocytic bone marrow inflammation and endosteal bone formation
B Görtz, S Hayer, J Zwerina, M Tohidast-Akrad, K Redlich, G Steiner, JS Smolen, G Schett
Distinct lymphocyte subpopulations in bone marrow from rheumatoid arthritis and osteoarthritis patients: a role for IL-15?
W Maslinski, E Warnawin, T Burakowski, L Jung, P Maldyk
Suppression of cbfa1 expression in C3H10T1/2 mesenchymal stem cells by anti-cbfa1 siRNA blocks osteoblastic develoment, but does not affect chondrogenesis
JO Gordeladze, D Noël, C Bony, C Joergensen
Abnormal collagen type I production in osteoarthritic subchondral bone is associated with a reduced capacity of osteoblasts to mineralize in vitro
I Aubry, A Delalandre, JC Fernandes, J Martel-Pelletier, J-P Pelletier, D Lajeunesse
Zoledronic acid protects from local and systemic bone loss in tumor necrosis factor-mediated arthritis
K Redlich, P Herrak, B Görtz, S Hayer, E Reiter, J Gasser, H Bergmeister, G Kollias, JS Smolen, G Schett
Cytokine networks in human severe combined immunodeficiency: a model for regulating T-cell homeostasis
DD Patel, V Tchernev, R Wolfinger, S Lezhnin, E Satyaraj, SA Kingsmore, RH Buckley
Different molecules at the surface of stimulated T cells induce IL-1α, tumor necrosis factor and IL-1 receptor antagonist in human monocytes
D Burger, N Molnarfi, L Gruaz, J-M Dayer
Regulation of T-cell differentiation by IL-4Rα-chain single nucleotide polymorphisms
I Prots, A Skapenko, S Mattyasovszky, CL Yoné, JR Kalden, H Schulze-Koops
GATA-3 in human T helper cell type 2 development
A Skapenko, J Leipe, U Niesner, K Devriendt, R Beetz, A Radbruch, JR Kalden, PE Lipsky, H Schulze-Koops
P-selectin, an important mediator of angiogenesis in females: the role of estradiol
AE Koch, OV Volpert, MV Volin, JM Woods, JH Ruth, CC Park, MA Amin
Effects of hypoxia on protein and gene expression in fibroblast-like synoviocytes
H El-Gabalawy, K Dasuri, C Hitchon, K Wong, G Ma, M Koshiji, S Der, O Wilkins, E Huang, J Wilkins
Long-term exposure of rheumatoid arthritis synovial fibroblasts to tumor necrosis factor alpha inhibits FasL-mediated apoptosis through activation of NF-κB and upregulation of the small ubiquitin-like modifier SUMO-1
T Pap, A Wille, A Drynda, M Neumann, A Baier, A Cinski, S Gay, I Meinecke
Tumor necrosis factor alpha modulates fibroblast-like synoviocyte expression of lymphangiogenesis-associated vascular endothelial growth factor C
AM Connor, A Narendran, E Bogoch, EC Keystone
A noninvasive magnetic resonance imaging-based method for assessing patellofemoral joint kinematics detects differences between healthy and symptomatic knees
NJ MacIntyre, NA Hill, RA Fellows, RE Ellis, DR Wilson
Perceived need for workplace accommodation and labour force participation in Canadian adults with arthritis disability
PP Wang, EM Badley, M Gignac
Magnetic resonance imaging, X-ray and dual X-ray absorptiometry techniques for assessment and monitoring of knee osteoarthritis
P Boulos, D Inglis, KA Beattie, G Ioannidis, CL Gordon, J Duryea, CE Webber, JD Adachi
Expression and regulation of microsomal prostaglandin E synthase-1 in human osteoarthritic cartilage and chondrocytes
H Afif, X Li, J Martel-Pelletier, J-P Pelletier, H Fahmi