Ausgabe 1/2018
Inhalt (261 Artikel)
Upregulation of Mas-related G Protein coupled receptor X2 in asthmatic lung mast cells and its activation by the novel neuropeptide hemokinin-1
Wichayapha Manorak, Chizobam Idahosa, Kshitij Gupta, Saptarshi Roy, Reynold Panettieri Jr, Hydar Ali
Inhibition of histone-deacetylase activity rescues inflammatory cystic fibrosis lung disease by modulating innate and adaptive immune responses
Manish Bodas, Steven Mazur, Taehong Min, Neeraj Vij
GM-CSF overexpression after influenza a virus infection prevents mortality and moderates M1-like airway monocyte/macrophage polarization
E. Scott Halstead, Todd M. Umstead, Michael L. Davies, Yuka Imamura Kawasawa, Patricia Silveyra, Judie Howyrlak, Linlin Yang, Weichao Guo, Sanmei Hu, Eranda Kurundu Hewage, Zissis C. Chroneos
Role and regulation of Abelson tyrosine kinase in Crk-associated substrate/profilin-1 interaction and airway smooth muscle contraction
Yinna Wang, Alyssa C. Rezey, Ruping Wang, Dale D. Tang
Urban particulate matter (PM) suppresses airway antibacterial defence
Xiaoyan Chen, Jinguo Liu, Jian Zhou, Jian Wang, Cuicui Chen, Yuanlin Song, Jue Pan
Biomarkers of inflammation in infants with cystic fibrosis
Theresa A. Laguna, Cynthia B. Williams, Myra G. Nunez, Cole Welchlin-Bradford, Catherine E. Moen, Cavan S. Reilly, Chris H. Wendt
Serum metabolic profiling identified a distinct metabolic signature in patients with idiopathic pulmonary fibrosis – a potential biomarker role for LysoPC
Barbara Rindlisbacher, Cornelia Schmid, Thomas Geiser, Cédric Bovet, Manuela Funke-Chambour
The association of the N-terminal pro-brain-type natriuretic peptide response to exercise with disease severity in therapy-naive pulmonary arterial hypertension: a cohort study
J. Kutsch, C. Faul, W. von Scheidt, M. Schwaiblmair, T. M. Berghaus
Effects of hypoxia and hyperoxia on the differential expression of VEGF-A isoforms and receptors in Idiopathic Pulmonary Fibrosis (IPF)
Shaney L. Barratt, Thomas Blythe, Khadija Ourradi, Caroline Jarrett, Gavin I. Welsh, David O. Bates, Ann B. Millar
Critical inhaler errors in asthma and COPD: a systematic review of impact on health outcomes
Omar Sharif Usmani, Federico Lavorini, Jonathan Marshall, William Christopher Nigel Dunlop, Louise Heron, Emily Farrington, Richard Dekhuijzen
Chronic obstructive pulmonary disease guidelines in Europe: a look into the future
Marc Miravitlles, Nicolas Roche, João Cardoso, David Halpin, Zaurbek Aisanov, Hannu Kankaanranta, Vladimir Kobližek, Paweł Śliwiński, Leif Bjermer, Michael Tamm, Francesco Blasi, Claus F. Vogelmeier
Prevalence and management of severe asthma in primary care: an observational cohort study in Sweden (PACEHR)
Kjell Larsson, Björn Ställberg, Karin Lisspers, Gunilla Telg, Gunnar Johansson, Marcus Thuresson, Christer Janson
Comparative analysis of COPD associated with tobacco smoking, biomass smoke exposure or both
Jordi Olloquequi, Sergio Jaime, Viviana Parra, Elizabeth Cornejo-Córdova, Gonzalo Valdivia, Àlvar Agustí, Rafael Silva O.
Radiation-induced pulmonary gene expression changes are attenuated by the CTGF antibody Pamrevlumab
Mark D. Sternlicht, Ute Wirkner, Sebastian Bickelhaupt, Ramon Lopez Perez, Alexandra Tietz, Kenneth E. Lipson, Todd W. Seeley, Peter E. Huber
Accumulation mode particles and LPS exposure induce TLR-4 dependent and independent inflammatory responses in the lung
Angela M. Fonceca, Graeme R. Zosky, Elizabeth M. Bozanich, Erika N. Sutanto, Anthony Kicic, Paul S. McNamara, Darryl A. Knight, Peter D. Sly, Debra J. Turner, Stephen M. Stick
IL-1β mediates lung neutrophilia and IL-33 expression in a mouse model of viral-induced asthma exacerbation
Irma Mahmutovic Persson, Mandy Menzel, Sangeetha Ramu, Samuel Cerps, Hamid Akbarshahi, Lena Uller
Molecular imaging of pulmonary diseases
Julien Dimastromatteo, Eric J. Charles, Victor E. Laubach
Long-acting bronchodilators improve exercise capacity in COPD patients: a systematic review and meta-analysis
Fabiano Di Marco, Giovanni Sotgiu, Pierachille Santus, Denis E. O’Donnell, Kai-Michael Beeh, Simone Dore, Maria Adelaide Roggi, Lisa Giuliani, Francesco Blasi, Stefano Centanni
Single-inhaler fluticasone furoate/umeclidinium/vilanterol versus fluticasone furoate/vilanterol plus umeclidinium using two inhalers for chronic obstructive pulmonary disease: a randomized non-inferiority study
Peter R. Bremner, Ruby Birk, Noushin Brealey, Afisi S. Ismaila, Chang-Qing Zhu, David A. Lipson
Association of thrombocytosis with COPD morbidity: the SPIROMICS and COPDGene cohorts
Ashraf Fawzy, Nirupama Putcha, Laura M. Paulin, Carrie P. Aaron, Wassim W. Labaki, MeiLan K. Han, Robert A. Wise, Richard E. Kanner, Russell P. Bowler, R. Graham Barr, Nadia N. Hansel, Neil E. Alexis, Wayne H. Anderson, Igor Barjaktarevic, R. Graham Barr, Eugene R. Bleecker, Richard C. Boucher, Russell P. Bowler, Elizabeth E. Carretta, Stephanie A. Christenson, Alejandro P. Comellas, Christopher B. Cooper, David J. Couper, Gerard J. Criner, Ronald G. Crystal, Jeffrey L. Curtis, Claire M. Doerschuk, Mark T. Dransfield, Christine M. Freeman, Mei Lan K. Han, Nadia N. Hansel, Annette T. Hastie, Eric A. Hoffman, Robert J. Kaner, Richard E. Kanner, Eric C. Kleerup, Jerry A. Krishnan, Lisa M. LaVange, Stephen C. Lazarus, Fernando J. Martinez, Deborah A. Meyers, Wendy C. Moore, John D. Newell Jr., Laura Paulin, Stephen Peters, Cheryl Pirozzi, Elizabeth C. Oelsner, Wanda K. O’Neal, Victor E. Ortega, Robert Paine, Nirupama Putcha, Sanjeev Raman, Stephen I. Rennard, Donald P. Tashkin, J. Michael Wells, Robert A. Wise, Prescott G. Woodruff
miR-34a is involved in CSE-induced apoptosis of human pulmonary microvascular endothelial cells by targeting Notch-1 receptor protein
Ying-Jiao Long, Xiao-Peng Liu, Shan-Shan Chen, Dan-Dan Zong, Yan Chen, Ping Chen
Long-term preservation of planar cell polarity in reversed tracheal epithelium
Takuya Tsuji, Ryosuke Nakamura, Tatsuya Katsuno, Yo Kishimoto, Atsushi Suehiro, Masaru Yamashita, Ryuji Uozumi, Tatsuo Nakamura, Ichiro Tateya, Koichi Omori
Differential effects of innate immune variants of surfactant protein-A1 (SFTPA1) and SP-A2 (SFTPA2) in airway function after Klebsiella pneumoniae infection and sex differences
Nithyananda Thorenoor, Xuesheng Zhang, Todd M. Umstead, E. Scott Halstead, David S. Phelps, Joanna Floros
The JAK2 pathway is activated in idiopathic pulmonary fibrosis
Javier Milara, Gracia Hernandez, Beatriz Ballester, Anselm Morell, Inés Roger, P. Montero, Juan Escrivá, José M. Lloris, Maria Molina-Molina, Esteban Morcillo, Julio Cortijo
The topical study of inhaled drug (salbutamol) delivery in idiopathic pulmonary fibrosis
Omar S. Usmani, Martyn F. Biddiscombe, Shuying Yang, Sally Meah, Eunice Oballa, Juliet K. Simpson, William A. Fahy, Richard P. Marshall, Pauline T. Lukey, Toby M. Maher
Characterizing undiagnosed chronic obstructive pulmonary disease: a systematic review and meta-analysis
Kate M. Johnson, Stirling Bryan, Shahzad Ghanbarian, Don D. Sin, Mohsen Sadatsafavi
Endothelial Cdc42 deficiency impairs endothelial regeneration and vascular repair after inflammatory vascular injury
Jiawen Lv, Junchao Zeng, Fukun Guo, Yiran Li, Mengying Xu, Yuanxiong Cheng, Lin Zhang, Shaoxi Cai, Yinghua Chen, Yi Zheng, Guodong Hu
Intermittent hypoxia promotes melanoma lung metastasis via oxidative stress and inflammation responses in a mouse model of obstructive sleep apnea
Lian Li, Fangyuan Ren, Chao Qi, Leiqian Xu, Yinshan Fang, Maoli Liang, Jing Feng, Baoyuan Chen, Wen Ning, Jie Cao
Role of ATP-sensitive potassium channels on hypoxic pulmonary vasoconstriction in endotoxemia
Maurizio Turzo, Julian Vaith, Felix Lasitschka, Markus A. Weigand, Cornelius J. Busch
Serum IgG subclass levels and risk of exacerbations and hospitalizations in patients with COPD
Fernando Sergio Leitao Filho, Seung Won Ra, Andre Mattman, Robert S. Schellenberg, Gerard J. Criner, Prescott G. Woodruff, Stephen C. Lazarus, Richard Albert, John E. Connett, Meilan K. Han, Fernando J. Martinez, Janice M. Leung, S. F. Paul Man, Shawn D. Aaron, Robert M. Reed, Don D. Sin
Relationship of CT-quantified emphysema, small airways disease and bronchial wall dimensions with physiological, inflammatory and infective measures in COPD
Kristoffer Ostridge, Nicholas P. Williams, Viktoriya Kim, Stephen Harden, Simon Bourne, Stuart C. Clarke, Emmanuel Aris, Sonia Mesia-Vela, Jeanne-Marie Devaster, Andrew Tuck, Anthony Williams, Stephen Wootton, Karl J. Staples, Tom M. A. Wilkinson
Idiopathic pulmonary fibrosis: pathogenesis and management
Giacomo Sgalla, Bruno Iovene, Mariarosaria Calvello, Margherita Ori, Francesco Varone, Luca Richeldi
Modulation of human airway smooth muscle biology by human adipocytes
Amanda Giesler, Manali Mukherjee, Katherine Radford, Luke Janssen, Parameswaran Nair
Impaired diversity of the lung microbiome predicts progression of idiopathic pulmonary fibrosis
Youhei Takahashi, Atsushi Saito, Hirofumi Chiba, Koji Kuronuma, Kimiyuki Ikeda, Tomofumi Kobayashi, Shigeru Ariki, Motoko Takahashi, Yasushi Sasaki, Hiroki Takahashi
Commenting on “Prognostic and diagnostic significance of copeptin in acute exacerbation of chronic obstructive pulmonary disease and acute heart failure: data from ACE 2 study” by Jacob A. Winther and colleagues
Luigi Mario Castello, Mattia Bellan
Favorable longitudinal change of lung function in patients with asthma-COPD overlap from a COPD cohort
Hye Yun Park, Suh-Young Lee, Danbee Kang, Juhee Cho, Hyun Lee, Seong Yong Lim, Ho Il Yoon, Seung Won Ra, Ki Uk Kim, Yeon-Mok Oh, Don D. Sin, Sang-Do Lee, Yong Bum Park
PM2.5 promotes human bronchial smooth muscle cell migration via the sonic hedgehog signaling pathway
Xiuqin Ye, Wei Hong, Binwei Hao, Gongyong Peng, Lingmei Huang, Zhuxiang Zhao, Yumin Zhou, Mengning Zheng, Chenglong Li, Chunxiao Liang, Erkang Yi, Jinding Pu, Bing Li, Pixin Ran
A phase IIb randomized, chronic-dosing, incomplete block, cross-over study of glycopyrronium, delivered via metered dose inhaler, compared with a placebo and an active control in patients with moderate-to-severe COPD
Edward M. Kerwin, Selwyn Spangenthal, Christine Kollar, Earl St Rose, Colin Reisner
Proteomic profiling of lung immune cells reveals dysregulation of phagocytotic pathways in female-dominated molecular COPD phenotype
Mingxing Yang, Maxie Kohler, Tina Heyder, Helena Forsslund, Hilde K. Garberg, Reza Karimi, Johan Grunewald, Frode S. Berven, Sven Nyrén, C. Magnus Sköld, Åsa M. Wheelock
Long-term smoking alters abundance of over half of the proteome in bronchoalveolar lavage cell in smokers with normal spirometry, with effects on molecular pathways associated with COPD
Mingxing Yang, Maxie Kohler, Tina Heyder, Helena Forsslund, Hilde K. Garberg, Reza Karimi, Johan Grunewald, Frode S. Berven, C. Magnus Sköld, Åsa M. Wheelock
Inhibition of cell-adhesion protein DPYSL3 promotes metastasis of lung cancer
Yang Yang, Yan Jiang, Dong Xie, Ming Liu, Nan Song, Junjie Zhu, Jiang Fan, Chenfang Zhu
Airway surface liquid from smokers promotes bacterial growth and biofilm formation via iron-lactoferrin imbalance
Luis G. Vargas Buonfiglio, Jennifer A. Borcherding, Mark Frommelt, Gavin J. Parker, Bryce Duchman, Oriana G. Vanegas Calderón, Ruth Fernandez-Ruiz, Julio E. Noriega, Elizabeth A. Stone, Alicia K. Gerke, Joseph Zabner, Alejandro P. Comellas
Factors associated with bronchiectasis in patients with uncontrolled asthma; the NOPES score: a study in 398 patients
A. Padilla-Galo, C. Olveira, L. Fernández de Rota-Garcia, I. Marco-Galve, A. J. Plata, A. Alvarez, F. Rivas-Ruiz, A. Carmona-Olveira, J. J. Cebrian-Gallardo, M. A. Martinez-Garcia
G908R NOD2 variant in a family with sarcoidosis
Valérie Besnard, Alain Calender, Diane Bouvry, Yves Pacheco, Catherine Chapelon-Abric, Florence Jeny, Hilario Nunes, Carole Planès, Dominique Valeyre
Increased circulating desmosine and age-dependent elastinolysis in idiopathic pulmonary fibrosis
Bart de Brouwer, Marjolein Drent, Jody M. W. van den Ouweland, Petal A. Wijnen, Coline H. M. van Moorsel, Otto Bekers, Jan C. Grutters, Eric S. White, Rob Janssen
Integrative genomics identifies new genes associated with severe COPD and emphysema
Phuwanat Sakornsakolpat, Jarrett D. Morrow, Peter J. Castaldi, Craig P. Hersh, Yohan Bossé, Edwin K. Silverman, Ani Manichaikul, Michael H. Cho
Plasma YKL-40 and NGAL are useful in distinguishing ACO from asthma and COPD
Jing Wang, Huajie Lv, Zhuang Luo, Shan Mou, Jing Liu, Chang Liu, Shiying Deng, Youfan Jiang, Jiachen Lin, Chengzhou Wu, Xianhong Liu, Jinzhi He, Depeng Jiang
Prediction equations of forced oscillation technique: the insidious role of collinearity
Hassib Narchi, Afaf AlBlooshi
Physical activity in the morning and afternoon is lower in patients with chronic obstructive pulmonary disease with morning symptoms
Amanda R. van Buul, Marise J. Kasteleyn, Niels H. Chavannes, Christian Taube
Regulation of alveolar macrophage death in acute lung inflammation
Erica K Y Fan, Jie Fan
Evaluation of oxidative stress biomarkers in idiopathic pulmonary fibrosis and therapeutic applications: a systematic review
Alessandro G. Fois, Panagiotis Paliogiannis, Salvatore Sotgia, Arduino A. Mangoni, Elisabetta Zinellu, Pietro Pirina, Ciriaco Carru, Angelo Zinellu
Oxidative stress enhances the expression of IL-33 in human airway epithelial cells
Hiroyuki Aizawa, Akira Koarai, Yutaka Shishikura, Satoru Yanagisawa, Mutsuo Yamaya, Hisatoshi Sugiura, Tadahisa Numakura, Mitsuhiro Yamada, Tomohiro Ichikawa, Naoya Fujino, Masafumi Noda, Yoshinori Okada, Masakazu Ichinose
The dopamine D1 receptor is expressed and induces CREB phosphorylation and MUC5AC expression in human airway epithelium
Nao Matsuyama, Sumire Shibata, Atsuko Matoba, Tada-aki Kudo, Jennifer Danielsson, Atsushi Kohjitani, Eiji Masaki, Charles W. Emala, Kentaro Mizuta
Airway disease phenotypes in animal models of cystic fibrosis
Alexandra McCarron, Martin Donnelley, David Parsons
A GATA3-specific DNAzyme attenuates sputum eosinophilia in eosinophilic COPD patients: a feasibility randomized clinical trial
Timm Greulich, Jens M. Hohlfeld, Petra Neuser, Katrin Lueer, Andreas Klemmer, Carmen Schade-Brittinger, Susanne Harnisch, Holger Garn, Harald Renz, Ursula Homburg, Jonas Renz, Anne Kirsten, Frauke Pedersen, Meike Müller, Claus F. Vogelmeier, Henrik Watz
The inhibition of human lung fibroblast proliferation and differentiation by Gs-coupled receptors is not predicted by the magnitude of cAMP response
Maxine J. Roberts, Rebecca E. Broome, Toby C. Kent, Steven J. Charlton, Elizabeth M. Rosethorne
Acute lung injury by gastric fluid instillation: activation of myofibroblast apoptosis during injury resolution
Pedro Ayala, Jorge Torres, Raúl Vivar, Manuel Meneses, Pablo Olmos, Tamara San Martin, Gisella R. Borzone
Crocin attenuates cigarette smoke-induced lung injury and cardiac dysfunction by anti-oxidative effects: the role of Nrf2 antioxidant system in preventing oxidative stress
Mahin Dianat, Maryam Radan, Mohammad Badavi, Seyyed Ali Mard, Vahid Bayati, Masoumeh Ahmadizadeh
The genetics of smoking in individuals with chronic obstructive pulmonary disease
Ma’en Obeidat, Guohai Zhou, Xuan Li, Nadia N. Hansel, Nicholas Rafaels, Rasika Mathias, Ingo Ruczinski, Terri H. Beaty, Kathleen C. Barnes, Peter D. Paré, Don D. Sin
Associations of the plasma lipidome with mortality in the acute respiratory distress syndrome: a longitudinal cohort study
Michael D. Maile, Theodore J. Standiford, Milo C. Engoren, Kathleen A. Stringer, Elizabeth S. Jewell, Thekkelnaycke M. Rajendiran, Tanu Soni, Charles F. Burant
Effect of continuous positive airway pressure on long-term cardiovascular outcomes in patients with coronary artery disease and obstructive sleep apnea: a systematic review and meta-analysis
Xiao Wang, Ying Zhang, Zhimin Dong, Jingyao Fan, Shaoping Nie, Yongxiang Wei
Pectoralis muscle area and mortality in smokers without airflow obstruction
Alejandro A. Diaz, Carlos H. Martinez, Rola Harmouche, Thomas P. Young, Merry-Lynn McDonald, James C. Ross, Mei Lan Han, Russell Bowler, Barry Make, Elizabeth A. Regan, Edwin K. Silverman, James Crapo, Aladin M. Boriek, Gregory L. Kinney, John E. Hokanson, Raul San Jose Estepar, George R. Washko
Assessing the healthcare resource use associated with inappropriate prescribing of inhaled corticosteroids for people with chronic obstructive pulmonary disease (COPD) in GOLD groups A or B: an observational study using the Clinical Practice Research Datalink (CPRD)
James D. Chalmers, Chris Poole, Samantha Webster, Abigail Tebboth, Scott Dickinson, Alicia Gayle
Proteolytic biomarkers are related to prognosis in COPD- report from a population-based cohort
Robert Linder, Eva Rönmark, Jamshid Pourazar, Annelie F. Behndig, Anders Blomberg, Anne Lindberg
Beclomethasone dipropionate and formoterol fumarate synergistically interact in hyperresponsive medium bronchi and small airways
Luigino Calzetta, Maria Gabriella Matera, Francesco Facciolo, Mario Cazzola, Paola Rogliani
Human alveolar macrophages predominately express combined classical M1 and M2 surface markers in steady state
Elena Mitsi, Raphael Kamng’ona, Jamie Rylance, Carla Solórzano, J. Jesus Reiné, Henry C. Mwandumba, Daniela M. Ferreira, Kondwani C. Jambo
FK506-binding protein 10 (FKBP10) regulates lung fibroblast migration via collagen VI synthesis
Larissa Knüppel, Katharina Heinzelmann, Michael Lindner, Rudolf Hatz, Jürgen Behr, Oliver Eickelberg, Claudia A. Staab-Weijnitz
Expression of MATE1, P-gp, OCTN1 and OCTN2, in epithelial and immune cells in the lung of COPD and healthy individuals
Tove Berg, Tove Hegelund-Myrbäck, Johan Öckinger, Xiao-Hong Zhou, Marie Brännström, Michael Hagemann-Jensen, Viktoria Werkström, Janeric Seidegård, Johan Grunewald, Magnus Nord, Lena Gustavsson
Recurrent inhibition of mitochondrial complex III induces chronic pulmonary vasoconstriction and glycolytic switch in the rat lung
Olga Rafikova, Anup Srivastava, Ankit A. Desai, Ruslan Rafikov, Stevan P. Tofovic
Correction to: Long-acting bronchodilators improve exercise capacity in COPD patients: a systematic review and meta-analysis
Fabiano Di Marco, Giovanni Sotgiu, Pierachille Santus, Denis E. O’Donnell, Kai-Michael Beeh, Simone Dore, Maria Adelaide Roggi, Lisa Giuliani, Francesco Blasi, Stefano Centanni
Resolution of bleomycin-induced murine pulmonary fibrosis via a splenic lymphocyte subpopulation
Koichiro Kamio, Arata Azuma, Kuniko Matsuda, Jiro Usuki, Minoru Inomata, Akemi Morinaga, Takeru Kashiwada, Nobuhiko Nishijima, Shioto Itakura, Nariaki Kokuho, Kenichiro Atsumi, Hiroki Hayashi, Tomoyoshi Yamaguchi, Kazue Fujita, Yoshinobu Saito, Shinji Abe, Kaoru Kubota, Akihiko Gemma
Abnormal pulmonary function tests predict the development of radiation-induced pneumonitis in advanced non-small cell lung Cancer
L. Torre-Bouscoulet, W. R. Muñoz-Montaño, D. Martínez-Briseño, F. J. Lozano-Ruiz, R. Fernández-Plata, J. A. Beck-Magaña, C. García-Sancho, A. Guzmán-Barragán, E. Vergara, M. Blake-Cerda, L. Gochicoa-Rangel, F. Maldonado, M. Arroyo-Hernández, O. Arrieta
Associations between comorbidities, their treatment and survival in patients with interstitial lung diseases – a claims data analysis
Larissa Schwarzkopf, Sabine Witt, Julia Waelscher, Markus Polke, Michael Kreuter
Rituximab for auto-immune alveolar proteinosis, a real life cohort study
Berenice Soyez, Raphael Borie, Cedric Menard, Jacques Cadranel, Leonidas Chavez, Vincent Cottin, Emmanuel Gomez, Sylvain Marchand-Adam, Sylvie Leroy, Jean-Marc Naccache, Hilario Nunes, Martine Reynaud-Gaubert, Laurent Savale, Abdellatif Tazi, Lidwine Wemeau-Stervinou, Marie-Pierre Debray, Bruno Crestani
Adverse events profile of oral corticosteroids among asthma patients in the UK: cohort study with a nested case-control analysis
Marlene Bloechliger, Daphne Reinau, Julia Spoendlin, Shih-Chen Chang, Klaus Kuhlbusch, Liam G. Heaney, Susan S. Jick, Christoph R. Meier
Prenatal fine particulate exposure associated with reduced childhood lung function and nasal epithelia GSTP1 hypermethylation: Sex-specific effects
Alison G. Lee, Blake Le Grand, Hsiao-Hsien Leon Hsu, Yueh-Hsiu Mathilda Chiu, Kasey J. Brennan, Sonali Bose, Maria José Rosa, Kelly J. Brunst, Itai Kloog, Ander Wilson, Joel Schwartz, Wayne Morgan, Brent A. Coull, Robert O. Wright, Andrea A. Baccarelli, Rosalind J. Wright
Correction to: Comparative analysis of COPD associated with tobacco smoking, biomass smoke exposure or both
Jordi Olloquequi, Sergio Jaime, Viviana Parra, Elizabeth Cornejo-Córdova, Gonzalo Valdivia, Àlvar Agustí, Rafael O. Silva
Altered lung biology of healthy never smokers following acute inhalation of E-cigarettes
Michelle R. Staudt, Jacqueline Salit, Robert J. Kaner, Charleen Hollmann, Ronald G. Crystal
Pollution and respiratory disease: can diet or supplements help? A review
T. Whyand, J. R. Hurst, M. Beckles, M. E. Caplin
Pulmonary inflammation-induced loss and subsequent recovery of skeletal muscle mass require functional poly-ubiquitin conjugation
Judith J. M. Ceelen, Annemie M. W. J. Schols, Nathalie G. M. Thielen, Astrid Haegens, Douglas A. Gray, Marco C. J. M. Kelders, Chiel C. de Theije, Ramon C. J. Langen
Trends in mortality from pneumonia in the Europe union: a temporal analysis of the European detailed mortality database between 2001 and 2014
Dominic C. Marshall, Ross J. Goodson, Yiwang Xu, Matthieu Komorowski, Joseph Shalhoub, Mahiben Maruthappu, Justin D. Salciccioli
A Serological Biomarker of Versican Degradation is Associated with Mortality Following Acute Exacerbations of Idiopathic Interstitial Pneumonia
Jannie M. B. Sand, Yoshinori Tanino, Morten A. Karsdal, Takefumi Nikaido, Kenichi Misa, Yuki Sato, Ryuichi Togawa, Xintao Wang, Diana J. Leeming, Mitsuru Munakata
Immunohistological features related to functional impairment in lymphangioleiomyomatosis
Ellen Caroline Toledo do Nascimento, Bruno Guedes Baldi, Alessandro Wasum Mariani, Raquel Annoni, Ronaldo Adib Kairalla, Suzana Pinheiro Pimenta, Luiz Fernando Ferraz da Silva, Carlos Roberto Ribeiro Carvalho, Marisa Dolhnikoff
Cost-effectiveness of lung volume reduction coil treatment in patients with severe emphysema: results from the 2-year follow-up crossover REVOLENS study (REVOLENS-2 study)
Julie Bulsei, Sylvie Leroy, Jeanne-Marie Perotin, Hervé Mal, Charles-Hugo Marquette, Hervé Dutau, Arnaud Bourdin, Jean-Michel Vergnon, Christophe Pison, Romain Kessler, Vincent Jounieaux, Mathieu Salaün, Armelle Marceau, Sylvain Dukic, Coralie Barbe, Margaux Bonnaire, Gaëtan Deslee, Isabelle Durand-Zaleski, Sandra Dury, Hervé Vallerand, François Lebargy, Claire Launois, Johanna Pradelli, Jonathan Benzaquen, Matthieu Buscot, Celine Sanfiorenzo, Sylvia Korzeniewski, Andrea Mazzetta, Jennifer Griffonnet, Ariane Guillemart, Demosthenes Makris, Christine Dombret, Frédérique Servin, Marie Pierre Debray, Sophie Laroumagne, Fabienne Bregeon, Carine Gomez, Philippe Astoul, Nathalie Lesavre, Jean Pierre Mallet, Anne Sophie Gamez, Philippe Tarodo, Christophe Brousse, Clément Broissin, Yoann Thibout, Fabrice Di Palma, Frédéric Costes, Amandine Briault, François Arbib, Emilie Reymond, G. Ferrettti, Michele Porzio, Benjamin Renaud-Picard, Bénédicte Toublanc, Géraldine François, Luc Thiberville, Géraldine François, Luc Thiberville, Antoine Cuvelier, Samy Lachkar, Delphine Gras, Philippe Benoit, Annick Leclainche, Damien Jolly, François Fourrier, Eric Hachulla, Nicolas Roche, Daniel Dusser
RETRACTED ARTICLE: The anti-proliferative and anti-inflammatory response of COPD airway smooth muscle cells to hydrogen sulfide
Mark M. Perry, Bernadett Tildy, Alberto Papi, Paolo Casolari, Gaetano Caramori, Karen Limbert Rempel, Andrew J. Halayko, Ian Adcock, Kian Fan Chung
Arterial stiffness in adults with steady-state bronchiectasis: association with clinical indices and disease severity
Yong-hua Gao, Juan-juan Cui, Ling-yun Wang, Ke-qin Yin, Li Wang, Guo-jun Zhang, Shao-xia Liu
Genetic analyses in a cohort of 191 pulmonary arterial hypertension patients
Hang Yang, Qixian Zeng, Yanyun Ma, Bingyang Liu, Qianlong Chen, Wenke Li, Changming Xiong, Zhou Zhou
Association between oncogenic status and risk of venous thromboembolism in patients with non-small cell lung cancer
Feifei Dou, Huiqiao Li, Min Zhu, Lirong Liang, Yuan Zhang, Jiawen Yi, Yuhui Zhang
Modelling the asthma phenotype: impact of cigarette smoke exposure
Maria G. Belvisi, Katie Baker, Nicole Malloy, Kristof Raemdonck, Bilel Dekkak, Michael Pieper, Anthony T. Nials, Mark A. Birrell
Fibrocytes are increased in lung and peripheral blood of patients with idiopathic pulmonary fibrosis
P. Heukels, J. A. C. van Hulst, M. van Nimwegen, C. E. Boorsma, B. N. Melgert, L. M. van den Toorn, K. A. T. Boomars, M. S. Wijsenbeek, H. Hoogsteden, J. H. von der Thüsen, R. W. Hendriks, M. Kool, B. van den Blink
Regulation of fibroblast Fas expression by soluble and mechanical pro-fibrotic stimuli
Amos E. Dodi, Iyabode O. Ajayi, Christine Chang, Meghan Beard, Shanna L. Ashley, Steven K. Huang, Victor J. Thannickal, Daniel J. Tschumperlin, Thomas H. Sisson, Jeffrey C. Horowitz
A candidate gene identification strategy utilizing mouse to human big-data mining: “3R-tenet” in COPD genetic research
Sangeetha Vishweswaraiah, Leema George, Natarajan Purushothaman, Koustav Ganguly
Effects and molecular mechanisms of intrauterine infection/inflammation on lung development
Jiarong Pan, Canyang Zhan, Tianming Yuan, Weiyan Wang, Ying Shen, Yi Sun, Tai Wu, Weizhong Gu, Lihua Chen, Huimin Yu
Metabolic reprogramming of the urea cycle pathway in experimental pulmonary arterial hypertension rats induced by monocrotaline
Hai-Kuo Zheng, Jun-Han Zhao, Yi Yan, Tian-Yu Lian, Jue Ye, Xiao-Jian Wang, Zhe Wang, Zhi-Cheng Jing, Yang-Yang He, Ping Yang
The aging lung: tissue telomere shortening in health and disease
Stephanie Everaerts, Elise J. Lammertyn, Dries S. Martens, Laurens J. De Sadeleer, Karen Maes, Aernoud A. van Batenburg, Roel Goldschmeding, Coline H. M. van Moorsel, Lieven J. Dupont, Wim A. Wuyts, Robin Vos, Ghislaine Gayan-Ramirez, Naftali Kaminski, James C. Hogg, Wim Janssens, Geert M. Verleden, Tim S. Nawrot, Stijn E. Verleden, John E. McDonough, Bart M. Vanaudenaerde
Knockdown of annexin A5 restores gefitinib sensitivity by promoting G2/M cell cycle arrest
Jian Zhou, Meijia Chang, Jing Li, Tao Fang, Jie Hu, Chunxue Bai
Soluble urokinase plasminogen activator receptor predicts mortality in exacerbated COPD
Nina S. Godtfredsen, Ditte V. Jørgensen, Kristoffer Marsaa, Charlotte S. Ulrik, Ove Andersen, Jesper Eugen-Olsen, Line J. H. Rasmussen
Hypoargininemia exacerbates airway hyperresponsiveness in a mouse model of asthma
Roy H. E. Cloots, Matthew E. Poynter, Els Terwindt, Wouter H. Lamers, S. Eleonore Köhler
Association of serum bilirubin level with lung function decline: a Korean community-based cohort study
Ah Young Leem, Ha Yan Kim, Young Sam Kim, Moo Suk Park, Joon Chang, Ji Ye Jung
Vascular inflammation and aortic stiffness: potential mechanisms of increased vascular risk in chronic obstructive pulmonary disease
Marie Fisk, Joseph Cheriyan, Divya Mohan, Carmel M. McEniery, Julia Forman, John R. Cockcroft, James H. F. Rudd, Ruth Tal-Singer, Nicholas S. Hopkinson, Michael I. Polkey, Ian B. Wilkinson
Quality of life assessment in interstitial lung diseases:a comparison of the disease-specific K-BILD with the generic EQ-5D-5L
Boglárka Lilla Szentes, Michael Kreuter, Thomas Bahmer, Surinder S. Birring, Martin Claussen, Julia Waelscher, Reiner Leidl, Larissa Schwarzkopf
Sequential broncho-alveolar lavages reflect distinct pulmonary compartments: clinical and research implications in lung transplantation
Liran Levy, Stephen C. Juvet, Kristen Boonstra, Lianne G. Singer, Sassan Azad, Betty Joe, Marcelo Cypel, Shaf Keshavjee, Tereza Martinu
Is the purinergic pathway involved in the pathology of COPD? Decreased lung CD39 expression at initial stages of COPD
Elisabet Aliagas, Mariana Muñoz-Esquerre, Ester Cuevas, Oriol Careta, Daniel Huertas, Marta López-Sánchez, Ignacio Escobar, Jordi Dorca, Salud Santos
Therapeutic effects of adipose-tissue-derived mesenchymal stromal cells and their extracellular vesicles in experimental silicosis
Elga Bandeira, Helena Oliveira, Johnatas D. Silva, Rubem F. S. Menna-Barreto, Christina M. Takyia, Jung S. Suk, Kenneth W. Witwer, Michael E. Paulaitis, Justin Hanes, Patricia R. M. Rocco, Marcelo M. Morales
A home monitoring program including real-time wireless home spirometry in idiopathic pulmonary fibrosis: a pilot study on experiences and barriers
C. C. Moor, M. Wapenaar, J. R. Miedema, J. J. M. Geelhoed, P. P. Chandoesing, M. S. Wijsenbeek
Anti-bacterial antibody and T cell responses in bronchiectasis are differentially associated with lung colonization and disease
Fathia G. Jaat, Sajidah F. Hasan, Audrey Perry, Sharon Cookson, Santosh Murali, John D. Perry, Clare V. Lanyon, Anthony De Soyza, Stephen M. Todryk
Rapid clearance of heavy chain-modified hyaluronan during resolving acute lung injury
Kevin Ni, Amar Gill, Victor Tseng, Andrew M. Mikosz, Kengo Koike, Erica L. Beatman, Cassie Y. Xu, Danting Cao, Fabienne Gally, Kara J. Mould, Karina A. Serban, Kelly S. Schweitzer, Keith L. March, William J. Janssen, Eva Nozik-Grayck, Stavros Garantziotis, Irina Petrache
The association between airway eosinophilic inflammation and IL-33 in stable non-atopic COPD
Damian Tworek, Sebastian Majewski, Karolina Szewczyk, Justyna Kiszałkiewicz, Zofia Kurmanowska, Paweł Górski, Ewa Brzeziańska-Lasota, Piotr Kuna, Adam Antczak
Human antigen R enhances the epithelial-mesenchymal transition via regulation of ZEB-1 in the human airway epithelium
Jian Sun, Xianmin Gu, Nan Wu, Pengju Zhang, Yi Liu, Shujuan Jiang
Uric acid, lung function, physical capacity and exacerbation frequency in patients with COPD: a multi-dimensional approach
Kathrin Kahnert, Peter Alter, Tobias Welte, Rudolf M. Huber, Jürgen Behr, Frank Biertz, Henrik Watz, Robert Bals, Claus F. Vogelmeier, Rudolf A. Jörres
Parthenolide attenuated bleomycin-induced pulmonary fibrosis via the NF-κB/Snail signaling pathway
Xiao-he Li, Ting Xiao, Jia-huan Yang, Yuan Qin, Jing-jing Gao, Hui-juan Liu, Hong-gang Zhou
Serum periostin does not reflect type 2-driven inflammation in COPD
O. A. Carpaij, F. O. W. Muntinghe, M. B. Wagenaar, J. W. Habing, W. Timens, H. A. M. Kerstjens, M. C. Nawijn, L. I. Z. Kunz, P. S. Hiemstra, G. W. Tew, C. T. J. Holweg, C. A. Brandsma, M. van den Berge
Is IgE or eosinophils the key player in allergic asthma pathogenesis? Are we asking the right question?
Andrea Matucci, Alessandra Vultaggio, Enrico Maggi, Ismail Kasujee
The therapeutic effect of mesenchymal stem cells on pulmonary myeloid cells following neonatal hyperoxic lung injury in mice
Ali Al-Rubaie, Andrea F. Wise, Foula Sozo, Robert De Matteo, Chrishan S. Samuel, Richard Harding, Sharon D. Ricardo
Hsa_circ_0046264 up-regulated BRCA2 to suppress lung cancer through targeting hsa-miR-1245
Liu Yang, Jun Wang, Yaodong Fan, Kun Yu, Baowei Jiao, Xiaosan Su
Correction to: Oxidative stress enhances the expression of IL-33 in human airway epithelial cells
Hiroyuki Aizawa, Akira Koarai, Yutaka Shishikura, Satoru Yanagisawa, Mutsuo Yamaya, Hisatoshi Sugiura, Tadahisa Numakura, Mitsuhiro Yamada, Tomohiro Ichikawa, Naoya Fujino, Masafumi Noda, Yoshinori Okada, Masakazu Ichinose
Decreased telomere length in the small airway epithelium suggests accelerated aging in the lungs of persons living with human immunodeficiency virus (HIV)
Stella Xu, Emily A. Vucic, Tawimas Shaipanich, Stephen Lam, Wan Lam, Julio S. Montaner, Don D. Sin, S. F. Paul Man, Janice M. Leung
Bone marrow characterization in COPD: a multi-level network analysis
Nuria Toledo-Pons, Guillaume Noell, Andreas Jahn, Amanda Iglesias, Maria Antonia Duran, Julio Iglesias, Angel Rios, Sergio Scrimini, Rosa Faner, Orlando Gigirey, Alvar Agustí, Borja G. Cosío
Microorganisms resistant to conventional antimicrobials in acute exacerbations of chronic obstructive pulmonary disease
Cristina Estirado, Adrian Ceccato, Monica Guerrero, Arturo Huerta, Catia Cilloniz, Olivia Vilaró, Albert Gabarrús, Joaquim Gea, Ernesto Crisafulli, Nestor Soler, Antoni Torres
PDGF-BB regulates the pulmonary vascular tone: impact of prostaglandins, calcium, MAPK- and PI3K/AKT/mTOR signalling and actin polymerisation in pulmonary veins of guinea pigs
Annette D. Rieg, Said Suleiman, Carolin Anker, Eva Verjans, Rolf Rossaint, Stefan Uhlig, Christian Martin
Indacaterol/glycopyrronium versus salmeterol/fluticasone in the prevention of clinically important deterioration in COPD: results from the FLAME study
Antonio R. Anzueto, Konstantinos Kostikas, Karen Mezzi, Steven Shen, Michael Larbig, Francesco Patalano, Robert Fogel, Donald Banerji, Jadwiga A. Wedzicha
Landscape of transcription and long non-coding RNAs reveals new insights into the inflammatory and fibrotic response following ventilator-induced lung injury
Lu Wang, Nannan Zhang, Yi Zhang, Jingen Xia, Qingyuan Zhan, Chen Wang
The human viral challenge model: accelerating the evaluation of respiratory antivirals, vaccines and novel diagnostics
Rob Lambkin-Williams, Nicolas Noulin, Alex Mann, Andrew Catchpole, Anthony S. Gilbert
Interleukin-32: its role in asthma and potential as a therapeutic agent
Tong Xin, Mo Chen, Liwei Duan, Yanling Xu, Peng Gao
Ciliated conical epithelial cell protrusions point towards a diagnosis of primary ciliary dyskinesia
Chris O’Callaghan, Andrew Rutman, Gwyneth Williams, Neeta Kulkarni, Joseph Hayes, Robert A. Hirst
Comparison of pro- and anti-inflammatory responses in paired human primary airway epithelial cells and alveolar macrophages
Reem Al Mubarak, Nicole Roberts, Robert J. Mason, Scott Alper, Hong Wei Chu
Changes in pulmonary endothelial cell properties during bleomycin-induced pulmonary fibrosis
Shinpei Kato, Naoki Inui, Akio Hakamata, Yuzo Suzuki, Noriyuki Enomoto, Tomoyuki Fujisawa, Yutaro Nakamura, Hiroshi Watanabe, Takafumi Suda
Circulating microRNAs and prediction of asthma exacerbation in childhood asthma
Alvin T. Kho, Michael J. McGeachie, Kip G. Moore, Jody M. Sylvia, Scott T. Weiss, Kelan G. Tantisira
Prevalence of asthma, aspirin sensitivity and allergy in chronic rhinosinusitis: data from the UK National Chronic Rhinosinusitis Epidemiology Study
Carl M. Philpott, Sally Erskine, Claire Hopkins, Nirmal Kumar, Shahram Anari, Naveed Kara, Sankalp Sunkaraneni, Jaydip Ray, Allan Clark, Andrew Wilson, Sally Erskine, Carl Philpott, Allan Clark, Claire Hopkins, Alasdair Robertson, Shahzada Ahmed, Naveed Kara, Sean Carrie, Vishnu Sunkaraneni, Jaydip Ray, Shahram Anari, Paul Jervis, Jaan Panesaar, Amir Farboud, Nirmal Kumar, Russell Cathcart, Robert Almeyda, Hisham Khalil, Peter Prinsley, Nicolas Mansell, Mahmoud Salam, Jonathan Hobson, Jane Woods, Emma Coombes
An attempt at modeling COPD epidemiological trends in France
Pierre-Régis Burgel, Caroline Laurendeau, Chantal Raherison, Claire Fuhrman, Nicolas Roche
Impact of immunization against OxLDL on the pulmonary response to cigarette smoke exposure in mice
Maude Talbot, Mélanie Hamel-Auger, Marie-Josée Beaulieu, Morgan Gazzola, Ariane Lechasseur, Sophie Aubin, Marie-Ève Paré, David Marsolais, Ynuk Bossé, Mathieu C. Morissette
A role for telomere length and chromosomal damage in idiopathic pulmonary fibrosis
John E. McDonough, Dries S. Martens, Naoya Tanabe, Farida Ahangari, Stijn E. Verleden, Karen Maes, Geert M. Verleden, Naftali Kaminski, James C. Hogg, Tim S. Nawrot, Wim A. Wuyts, Bart M. Vanaudenaerde
Anti-inflammatory duration of action of fluticasone furoate/vilanterol trifenatate in asthma: a cross-over randomised controlled trial
George Bardsley, Peter Daley-Yates, Amanda Baines, Rodger Kempsford, Mathew Williams, Tony Mallon, Irene Braithwaite, Kylie Riddell, Shashidhar Joshi, Philippe Bareille, Richard Beasley, James Fingleton
Serial blood eosinophils and clinical outcome in patients with chronic obstructive pulmonary disease
Sun Hye Shin, Hye Yun Park, Danbee Kang, Juhee Cho, Sung Ok Kwon, Joo Hun Park, Jae Seung Lee, Yeon-Mok Oh, Don D. Sin, Woo Jin Kim, Sang-Do Lee
Cryobiopsies are diagnostic in Pleuroparenchymal and Airway-centered Fibroelastosis
Sissel Kronborg-White, Claudia Ravaglia, Alessandra Dubini, Sara Piciucchi, Sara Tomassetti, Elisabeth Bendstrup, Venerino Poletti
Epithelial mesenchymal transition (EMT): a universal process in lung diseases with implications for cystic fibrosis pathophysiology
Nathan Rout-Pitt, Nigel Farrow, David Parsons, Martin Donnelley
Health status decline in α-1 antitrypsin deficiency: a feasible outcome for disease modifying therapies?
Robert A. Stockley, Ross G. Edgar, Sian Starkey, Alice M. Turner
Human alveolar epithelial cells type II are capable of TGFβ-dependent epithelial-mesenchymal-transition and collagen-synthesis
Torsten Goldmann, Gernot Zissel, Henrik Watz, Daniel Drömann, Martin Reck, Christian Kugler, Klaus F. Rabe, Sebastian Marwitz
Lower respiratory tract microbial composition was diversified in Pseudomonas aeruginosa ventilator-associated pneumonia patients
Xiaoling Qi, Hongping Qu, Dandan Yang, Lian Zhou, Ya-Wen He, Yuetian Yu, Jieming Qu, Jialin Liu
Decreased microbiome diversity in the HIV small airway epithelium
Stella Xu, Amy Tsai, Marc A. Sze, Emily A. Vucic, Tawimas Shaipanich, Marianne Harris, Silvia Guillemi, Julia Yang, Sunita Sinha, Corey Nislow, Julio Montaner, Wan Lam, Stephen Lam, Don D. Sin, S. F. Paul Man, Janice M. Leung
The European IPF registry (eurIPFreg): baseline characteristics and survival of patients with idiopathic pulmonary fibrosis
Andreas Guenther, Ekaterina Krauss, Silke Tello, Jasmin Wagner, Bettina Paul, Stefan Kuhn, Olga Maurer, Sabine Heinemann, Ulrich Costabel, María Asunción Nieto Barbero, Veronika Müller, Philippe Bonniaud, Carlo Vancheri, Athol Wells, Martina Vasakova, Alberto Pesci, Matteo Sofia, Walter Klepetko, Werner Seeger, Fotios Drakopanagiotakis, Bruno Crestani
Adenosine 5’-triphosphate’s role in bradycardia and syncope associated with pulmonary embolism
Amir Pelleg, Edward S. Schulman, Peter J. Barnes
Impact of radiologically stratified exacerbations: insights into pneumonia aetiology in COPD
Nicholas P. Williams, Kristoffer Ostridge, Jeanne-Marie Devaster, Viktoriya Kim, Ngaire A. Coombs, Simon Bourne, Stuart C. Clarke, Stephen Harden, Ausami Abbas, Emmanuel Aris, Christophe Lambert, Andrew Tuck, Anthony Williams, Stephen Wootton, Karl J. Staples, Tom M. A. Wilkinson, J. Alnajar, R. Anderson, E. Aris, W. R. Ballou, A. Barton, S. Bourne, M. Caubet, S. C. Clarke, D. Cleary, C. Cohet, N. A. Coombs, K. Cox, J.-M. Devaster, V. Devine, N. Devos, E. Dineen, T. Elliot, R. Gladstone, S. Harden, J. Jefferies, V. Kim, C. Lambert, S. Mesia-Vela, P. Moris, K. Ostridge, T. G. Pascal, M. Peeters, S. Schoonbroodt, K. J. Staples, A. Tuck, L. Welsh, V. Weynants, T. M. A. Wilkinson, A. P. Williams, N. P. Williams, C. Woelk, M. Wojtas, S. Wootton
Regulatory role of heme oxygenase-1 in silica-induced lung injury
Kentaro Nakashima, Takashi Sato, Suguru Shigemori, Takeshi Shimosato, Masaharu Shinkai, Takeshi Kaneko
Influenza A virus infection dysregulates the expression of microRNA-22 and its targets; CD147 and HDAC4, in epithelium of asthmatics
Fatemeh Moheimani, Jorinke Koops, Teresa Williams, Andrew T. Reid, Philip M. Hansbro, Peter A. Wark, Darryl A. Knight
Asthmatic bronchial epithelial cells promote the establishment of a Hyaluronan-enriched, leukocyte-adhesive extracellular matrix by lung fibroblasts
Stephen R. Reeves, Inkyung Kang, Christina K. Chan, Kaitlyn A. Barrow, Tessa K. Kolstad, Maria P. White, Steven F. Ziegler, Thomas N. Wight, Jason S. Debley
The diagnostic performance of patient symptoms in screening for COPD
Kate M. Johnson, Wan C. Tan, Jean Bourbeau, Don D. Sin, Mohsen Sadatsafavi, Jean Bourbeau, Wan C. Tan, J. Mark FitzGerald, Don Sin, Darcy Marciniuk, Dennis E. O’Donnell, Paul Hernandez, Kenneth R. Chapman, Robert Cowie, Shawn Aaron, F. Maltais, Jonathon Samet, Milo Puhan, Qutayba Hamid, James C. Hogg, Jean Bourbeau, Carole Jabet, Palmina Mancino, Wan C. Tan, Don Sin, Sheena Tam, Jeremy Road, Joe Comeau, Adrian Png, Harvey Coxson, Jonathon Leipsic, Cameron Hague, Mohsen Sadatsafavi, Teresa To, Andrea Gershon, Wan C. Tan, Harvey Coxson, Jean Bourbeau, Pei Zhi Li, Zhi Song, Yvan Fortier, Andrea Benedetti, Dennis Jensen, Wan C. Tan, Christine Lo, Sarah Cheng, Cindy Fung, Nancy Haynes, Junior Chuang, Licong Li, Selva Bayat, Amanda Wong, Zoe Alavi, Catherine Peng, Bin Zhao, Nathalie Scott-Hsiung, Tasha Nadirshaw, Jean Bourbeau, Palmina Mancino, David Latreille, Jacinthe Baril, Laura Labonté, Kenneth Chapman, Patricia McClean, Nadeen Audisho, R. Cowie, B. Walter, Ann Cowie, Curtis Dumonceaux, Lisette Machado, Paul Hernandez, Scott Fulton, Kristen Osterling, Shawn Aaron, Kathy Vandemheen, Gay Pratt, Amanda Bergeron, Denis O’Donnell, Matthew McNeil, Kate Whelan, François Maltais, Cynthia Brouillard, Darcy Marciniuk, Ron Clemens, Janet Baran
Understanding alveolarization to induce lung regeneration
José Alberto Rodríguez-Castillo, David Bravo Pérez, Aglaia Ntokou, Werner Seeger, Rory E. Morty, Katrin Ahlbrecht
Neuropeptides in asthma, chronic obstructive pulmonary disease and cystic fibrosis
Kalina R. Atanasova, Leah R. Reznikov
Augmented expression of Ki-67 is correlated with clinicopathological characteristics and prognosis for lung cancer patients: an up-dated systematic review and meta-analysis with 108 studies and 14,732 patients
Dan-ming Wei, Wen-jie Chen, Rong-mei Meng, Na Zhao, Xiang-yu Zhang, Dan-yu Liao, Gang Chen
Real world evaluation of a novel lateral flow assay (AlphaKit® QuickScreen) for the detection of alpha-1-antitrypsin deficiency
Timm Greulich, Francisco Rodríguez-Frias, Irene Belmonte, Andreas Klemmer, Claus F. Vogelmeier, Marc Miravitlles
Age and African-American race impact the validity and reliability of the asthma control test in persistent asthmatics
Allison J. Burbank, Krista Todoric, Pamela Steele, Jonathan Rosen, Haibo Zhou, Marcia Frye, Ceila E. Loughlin, Sally Ivins, Katherine Mills, Lauren Dembnicki Massey, Bryce B. Reeve, Michelle L. Hernandez
Comprehensive gene expression profiling identifies distinct and overlapping transcriptional profiles in non-specific interstitial pneumonia and idiopathic pulmonary fibrosis
Matthew J. Cecchini, Karishma Hosein, Christopher J. Howlett, Mariamma Joseph, Marco Mura
The use of intravenous versus subcutaneous monoclonal antibodies in the treatment of severe asthma: a review
Andrea Matucci, Alessandra Vultaggio, Romano Danesi
Glucocorticoids influence versican and chondroitin sulphate proteoglycan levels in the fetal sheep lung
Annie R. A. McDougall, Amanda J. Fosang, Jessica Faggian, Megan J. Wallace, Kelly J. Crossley, Timothy J. Cole, Stuart B. Hooper
SERPINA1 methylation and lung function in tobacco-smoke exposed European children and adults: a meta-analysis of ALEC population-based cohorts
Anna Beckmeyer-Borowko, Medea Imboden, Faisal I. Rezwan, Matthias Wielscher, Andre F. S. Amaral, Ayoung Jeong, Emmanuel Schaffner, Juha Auvinen, Sylvain Sebert, Ville Karhunen, Robert Bettschart, Alexander Turk, Marco Pons, Daiana Stolz, Florian Kronenberg, Ryan Arathimos, Gemma C. Sharp, Caroline Relton, Alexander J. Henderson, Marjo-Riitta Jarvelin, Deborah Jarvis, John W. Holloway, Nicole M. Probst-Hensch
Protein kinase R-like endoplasmic reticulum kinase is a mediator of stretch in ventilator-induced lung injury
Tamás Dolinay, Chanat Aonbangkhen, William Zacharias, Edward Cantu, Jennifer Pogoriler, Alec Stablow, Gladys G. Lawrence, Yoshikazu Suzuki, David M. Chenoweth, Edward Morrisey, Jason D. Christie, Michael F. Beers, Susan S. Margulies
Prevalence and incidence of sarcoidosis in Korea: a nationwide population-based study
Hee-Young Yoon, Hyeong Min Kim, Ye-Jee Kim, Jin Woo Song
The underestimated danger of E-cigarettes - also in the absence of nicotine
Martina Korfei
Transforming growth factor beta1 targets estrogen receptor signaling in bronchial epithelial cells
L. Cody Smith, Santiago Moreno, Lauren Robertson, Sarah Robinson, Kristal Gant, Andrew J. Bryant, Tara Sabo-Attwood
Primary data, claims data, and linked data in observational research: the case of COPD in Germany
Sabrina Mueller, Fraence Gottschalk, Antje Groth, Wilhelmine Meeraus, Maurice Driessen, Thomas Kohlmann, Thomas Wilke
Clinical significance of radiological pleuroparenchymal fibroelastosis pattern in interstitial lung disease patients registered for lung transplantation: a retrospective cohort study
Kiminobu Tanizawa, Tomohiro Handa, Takeshi Kubo, Toyofumi F. Chen-Yoshikawa, Akihiro Aoyama, Hideki Motoyama, Kyoko Hijiya, Akihiko Yoshizawa, Yohei Oshima, Kohei Ikezoe, Shinsaku Tokuda, Yoshinari Nakatsuka, Yuko Murase, Sonoko Nagai, Shigeo Muro, Toru Oga, Kazuo Chin, Toyohiro Hirai, Hiroshi Date
Better approach for autoimmune pulmonary alveolar proteinosis treatment: inhaled or subcutaneous granulocyte-macrophage colony-stimulating factor: a meta-analyses
Gaohong Sheng, Peng Chen, Yanqiu Wei, Jiaojiao Chu, Xiaolei Cao, Hui-Lan Zhang
Carbon monoxide levels after inhalation from new generation heated tobacco products
Pasquale Caponnetto, Marilena Maglia, Gaetano Prosperini, Barbara Busà, Riccardo Polosa
Elastin degradation products in acute lung injury induced by gastric contents aspiration
Pedro Ayala, Raúl Vivar, Rebeca Montalva, Pablo Olmos, Manuel Meneses, Gisella R. Borzone
Relationship of systemic IL-10 levels with proinflammatory cytokine responsiveness and lung function in agriculture workers
Tricia D. LeVan, Debra J. Romberger, Mohammad Siahpush, Brandon L. Grimm, Athena K. Ramos, Patrik L. Johansson, Tzeyu L. Michaud, Art J. Heires, Todd A. Wyatt, Jill A. Poole
Anti-acid therapy in idiopathic pulmonary fibrosis: insights from the INPULSIS® trials
Ulrich Costabel, Jürgen Behr, Bruno Crestani, Wibke Stansen, Rozsa Schlenker-Herceg, Susanne Stowasser, Ganesh Raghu
Health care resource utilization and cost for asthma patients regularly treated with oral corticosteroids – a Swedish observational cohort study (PACEHR)
Christer Janson, Karin Lisspers, Björn Ställberg, Gunnar Johansson, Gunilla Telg, Marcus Thuresson, Helene Nordahl Christensen, Kjell Larsson
Serum sST2 levels predict severe exacerbation of asthma
Masato Watanabe, Keitaro Nakamoto, Toshiya Inui, Mitsuru Sada, Kojiro Honda, Masaki Tamura, Yukari Ogawa, Takuma Yokoyama, Takeshi Saraya, Daisuke Kurai, Haruyuki Ishii, Hajime Takizawa
Macrophages: friend or foe in idiopathic pulmonary fibrosis?
Lei Zhang, Yi Wang, Guorao Wu, Weining Xiong, Weikuan Gu, Cong-Yi Wang
Combined diffusing capacity for nitric oxide and carbon monoxide as predictor of bronchiolitis obliterans syndrome following lung transplantation
Anna Winkler, Kathrin Kahnert, Jürgen Behr, Claus Neurohr, Nikolaus Kneidinger, Rudolf Hatz, Holger Dressel, Thomas Radtke, Rudolf A. Jörres
Identifying the associated risks of pneumonia in COPD patients: ARCTIC an observational study
Christer Janson, Gunnar Johansson, Björn Ställberg, Karin Lisspers, Petter Olsson, Dorothy L. Keininger, Milica Uhde, Florian S. Gutzwiller, Leif Jörgensen, Kjell Larsson
Impairment of respiratory muscle strength in Berardinelli-Seip congenital lipodystrophy subjects
Jorge Luiz Dantas de Medeiros, Bruno Carneiro Bezerra, Thiago Anderson Brito de Araújo, Aquiles Sales Craveiro Sarmento, Lázaro Batista de Azevedo Medeiros, Lucien Peroni Gualdi, Maria do Socorro Luna Cruz, Thaiza Teixeira Xavier Nobre, Josivan Gomes Lima, Julliane Tamara Araújo de Melo Campos
Smoking is associated with quantifiable differences in the human lung DNA virome and metabolome
Ann C. Gregory, Matthew B. Sullivan, Leopoldo N. Segal, Brian C. Keller
Differential effects of Nintedanib and Pirfenidone on lung alveolar epithelial cell function in ex vivo murine and human lung tissue cultures of pulmonary fibrosis
Mareike Lehmann, Lara Buhl, Hani N. Alsafadi, Stephan Klee, Sarah Hermann, Kathrin Mutze, Chiharu Ota, Michael Lindner, Jürgen Behr, Anne Hilgendorff, Darcy E. Wagner, Melanie Königshoff
Steroid insensitive fixed airflow obstruction is not related to airway inflammation in older non-smokers with asthma
K. O. Tonga, G. G. King, C. S. Farah, C. Thamrin, F. S. Tang, J. Santos, P. Sharma, D. G. Chapman, B. G. Oliver
What have we learned from observational studies and clinical trials of mild to moderate COPD?
Miriam Barrecheguren, Cruz González, Marc Miravitlles
Imaging-based clusters in current smokers of the COPD cohort associate with clinical characteristics: the SubPopulations and Intermediate Outcome Measures in COPD Study (SPIROMICS)
Babak Haghighi, Sanghun Choi, Jiwoong Choi, Eric A. Hoffman, Alejandro P. Comellas, John D. Newell Jr, R. Graham Barr, Eugene Bleecker, Christopher B. Cooper, David Couper, Mei Lan Han, Nadia N. Hansel, Richard E. Kanner, Ella A. Kazerooni, Eric A. C. Kleerup, Fernando J. Martinez, Wanda O’Neal, Stephen I. Rennard, Prescott G. Woodruff, Ching-Long Lin
Leptin receptor gene polymorphisms and sex modify the association between acetaminophen use and asthma among young adults: results from two observational studies
Ali H. Ziyab, Nandini Mukherjee, Ramesh J. Kurukulaaratchy, Hongmei Zhang, Susan Ewart, Hasan Arshad, Wilfried Karmaus
Proteinase 3; a potential target in chronic obstructive pulmonary disease and other chronic inflammatory diseases
Helena Crisford, Elizabeth Sapey, Robert A. Stockley
Inhaled furosemide for relief of air hunger versus sense of breathing effort: a randomized controlled trial
Joanna C. Grogono, Clare Butler, Hooshang Izadi, Shakeeb H. Moosavi
Short and long-term effects of pulmonary rehabilitation in interstitial lung diseases: a randomised controlled trial
Silvia Perez-Bogerd, Wim Wuyts, Veronica Barbier, Heleen Demeyer, Alain Van Muylem, Wim Janssens, Thierry Troosters
Serum phosphate and phosphate-regulatory hormones in COPD patients
Alexandra Stroda, Vincent Brandenburg, Ayham Daher, Christian Cornelissen, Claudia Goettsch, András Keszei, Michael Dreher
The impact of HIV on the prevalence of asthma in Uganda: a general population survey
Bruce J. Kirenga, Levicatus Mugenyi, Corina de Jong, J. Lucian Davis, Winceslaus Katagira, Thys van der Molen, Moses R. Kamya, Marike Boezen
Significant predictors of medically diagnosed chronic obstructive pulmonary disease in patients with preserved ratio impaired spirometry: a 3-year cohort study
Hye Jung Park, Min Kwang Byun, Chin Kook Rhee, Kyungjoo Kim, Hyung Jung Kim, Kwang-Ha Yoo
A circulating cell population showing both M1 and M2 monocyte/macrophage surface markers characterizes systemic sclerosis patients with lung involvement
Amelia Chiara Trombetta, Stefano Soldano, Paola Contini, Veronica Tomatis, Barbara Ruaro, Sabrina Paolino, Renata Brizzolara, Paola Montagna, Alberto Sulli, Carmen Pizzorni, Vanessa Smith, Maurizio Cutolo
PrtA immunization fails to protect against pulmonary and invasive infection by Streptococcus pneumoniae
Chen-Fang Hsu, Chen-Hao Hsiao, Shun-Fu Tseng, Jian-Ru Chen, Yu-Jou Liao, Sy-Jou Chen, Chin-Sheng Lin, Huey-Kang Sytwu, Yi-Ping Chuang
IL-32γ attenuates airway fibrosis by modulating the integrin-FAK signaling pathway in fibroblasts
Gyong Hwa Hong, So-Young Park, Hyouk-Soo Kwon, Bo-Ram Bang, Jaechun Lee, Sang-Yeob Kim, Chan-Gi Pack, Soohyun Kim, Keun-Ai Moon, Tae-Bum Kim, Hee-Bom Moon, You Sook Cho
The prostaglandin D2 receptor 2 pathway in asthma: a key player in airway inflammation
Christian Domingo, Oscar Palomares, David A. Sandham, Veit J. Erpenbeck, Pablo Altman
Dual effects of human neutrophil peptides in a mouse model of pneumonia and ventilator-induced lung injury
Junbo Zheng, Yongbo Huang, Diana Islam, Xiao-Yan Wen, Sulong Wu, Catherine Streutker, Alice Luo, Manshu Li, Julie Khang, Bing Han, Nanshan Zhong, Yimin Li, Kaijiang Yu, Haibo Zhang
Rectal, central venous, gastric and bladder pressures versus esophageal pressure for the measurement of cough strength: a prospective clinical comparison
Lluís G. Aguilera, Lluís Gallart, Juan C. Álvarez, Jordi Vallès, Joaquim Gea
Good response to PAH-targeted drugs in a PVOD patient carrying Biallelic EIF2AK4 mutation
Li Liang, Hua Su, Xiuqing Ma, Ruifeng Zhang
The moderate predictive value of serial serum CRP and PCT levels for the prognosis of hospitalized community-acquired pneumonia
Shuren Guo, Xiaohuan Mao, Ming Liang
MiRNA expression profiles in healthy OSAHS and OSAHS with arterial hypertension: potential diagnostic and early warning markers
Xiuping Yang, Xun Niu, Ying Xiao, Kun Lin, Xiong Chen
Characteristics of lung cancer among patients with idiopathic pulmonary fibrosis and interstitial lung disease – analysis of institutional and population data
Joo Heung Yoon, Mehdi Nouraie, Xiaoping Chen, Richard H Zou, Jacobo Sellares, Kristen L Veraldi, Jared Chiarchiaro, Kathleen Lindell, David O Wilson, Naftali Kaminski, Timothy Burns, Humberto Trejo Bittar, Samuel Yousem, Kevin Gibson, Daniel J Kass
Concomitant inhaled corticosteroid use and the risk of pneumonia in COPD: a matched-subgroup post hoc analysis of the UPLIFT® trial
Donald P. Tashkin, Marc Miravitlles, Bartolomé R. Celli, Norbert Metzdorf, Achim Mueller, David M. G. Halpin, Antonio Anzueto
Elevated serum soluble programmed cell death ligand 1 concentration as a potential marker for poor prognosis in small cell lung cancer patients with chemotherapy
Jianjun Jin, Jiming Si, Yuanhua Liu, Huanqin Wang, Ran Ni, Jing Wang
Antiestrogen- and tamoxifen-induced effects on calcium-activated chloride currents in epithelial cells carrying the ∆F508-CFTR point mutation
Roberto Imberti, Maria Lisa Garavaglia, Ivan Verduci, Gaetano Cannavale, Giorgio Balduzzi, Sara Papetti, Michele Mazzanti
A biomarker basing on radiomics for the prediction of overall survival in non–small cell lung cancer patients
Bo He, Wei Zhao, Jiang-Yuan Pi, Dan Han, Yuan-Ming Jiang, Zhen-Guang Zhang, Wei Zhao
Upregulation of microRNA-17-5p contributes to hypoxia-induced proliferation in human pulmonary artery smooth muscle cells through modulation of p21 and PTEN
Guangjie Liu, Peng Hao, Jie Xu, Liming Wang, Yuchuan Wang, Ruifang Han, Ming Ying, Shuangshuang Sui, Jinghua Liu, Xuan Li
cGMP interacts with tropomyosin and downregulates actin-tropomyosin-myosin complex interaction
Lihui Zou, Junhua Zhang, Jingli Han, Wenqing Li, Fei Su, Xiaomao Xu, Zhenguo Zhai, Fei Xiao
High-flow nasal cannula in adults with acute respiratory failure and after extubation: a systematic review and meta-analysis
Zhiheng Xu, Yimin Li, Jianmeng Zhou, Xi Li, Yongbo Huang, Xiaoqing Liu, Karen E. A. Burns, Nanshan Zhong, Haibo Zhang
Efficacy and safety of nintedanib in advanced idiopathic pulmonary fibrosis
Hee-Young Yoon, Sojung Park, Dong Soon Kim, Jin Woo Song
Culture of human alveolar epithelial type II cells by sprouting
Petra Khan, Kleanthis Fytianos, Luca Tamò, Michael Roth, Michael Tamm, Thomas Geiser, Amiq Gazdhar, Katrin E Hostettler
Efficacy and effectiveness of Ceftaroline Fosamil in patients with pneumonia: a systematic review and meta-analysis
Giovanni Sotgiu, Stefano Aliberti, Andrea Gramegna, Marco Mantero, Marta Di Pasquale, Federica Trogu, Laura Saderi, Francesco Blasi
FBXO17 promotes cell proliferation through activation of Akt in lung adenocarcinoma cells
Tomeka L. Suber, Ina Nikolli, Michael E. O’Brien, James Londino, Jing Zhao, Kong Chen, Rama K. Mallampalli, Yutong Zhao
Selective activation and proliferation of a quiescent stem cell population in the neuroepithelial body microenvironment
Line Verckist, Isabel Pintelon, Jean-Pierre Timmermans, Inge Brouns, Dirk Adriaensen
Modulation of airway hyperresponsiveness by rhinovirus exposure
Dennis Lo, Joshua L. Kennedy, Richard C. Kurten, Reynold A. Panettieri Jr, Cynthia J. Koziol-White
Childhood asthma is associated with COPD and known asthma variants in COPDGene: a genome-wide association study
Lystra P. Hayden, Michael H. Cho, Benjamin A. Raby, Terri H. Beaty, Edwin K. Silverman, Craig P. Hersh, James D. Crapo, Edwin K. Silverman, Barry J. Make, Elizabeth A. Regan, Terri Beaty, Ferdouse Begum, Peter J. Castaldi, Michael Cho, Dawn L. DeMeo, Adel R. Boueiz, Marilyn G. Foreman, Eitan Halper-Stromberg, Lystra P. Hayden, Craig P. Hersh, Jacqueline Hetmanski, Brian D. Hobbs, John E. Hokanson, Nan Laird, Christoph Lange, Sharon M. Lutz, Merry-Lynn McDonald, Margaret M. Parker, Dandi Qiao, Elizabeth A. Regan, Edwin K. Silverman, Emily S. Wan, Sungho Won, Phuwanat Sakornsakolpat, Dmitry Prokopenko, Mustafa Al Qaisi, Harvey O. Coxson, Teresa Gray, Mei Lan K. Han, Eric A. Hoffman, Stephen Humphries, Francine L. Jacobson, Philip F. Judy, Ella A. Kazerooni, Alex Kluiber, David A. Lynch, John D. Newell Jr, Elizabeth A. Regan, James C. Ross, Raul San Jose Estepar, Joyce Schroeder, Jered Sieren, Douglas Stinson, Berend C. Stoel, Juerg Tschirren, Edwin Van Beek, Bram van Ginneken, Eva van Rikxoort, George Washko, Carla G. Wilson, Robert Jensen, Douglas Everett, Jim Crooks, Camille Moore, Matt Strand, Carla G. Wilson, John E. Hokanson, John Hughes, Gregory Kinney, Sharon M. Lutz, Katherine Pratte, Kendra A. Young, Surya Bhatt, Jessica Bon, Mei Lan K. Han, Barry Make, Carlos Martinez, Susan Murray, Elizabeth Regan, Xavier Soler, Carla G. Wilson, Russell P. Bowler, Katerina Kechris, Farnoush Banaei-Kashani, Jeffrey L. Curtis, Carlos H. Martinez, Perry G. Pernicano, Nicola Hanania, Philip Alapat, Mustafa Atik, Venkata Bandi, Aladin Boriek, Kalpatha Guntupalli, Elizabeth Guy, Arun Nachiappan, Amit Parulekar, Dawn L. DeMeo, Craig Hersh, Francine L. Jacobson, George Washko, Graham Barr, John Austin, Belinda D’Souza, Gregory D. N. Pearson, Anna Rozenshtein, Byron Thomashow, Neil MacIntyre Jr, Page McAdams, Lacey Washington, Charlene McEvoy, Joseph Tashjian, Robert Wise, Robert Brown, Nadia N. Hansel, Karen Horton, Allison Lambert, Nirupama Putcha, Richard Casaburi, Alessandra Adami, Matthew Budoff, Hans Fischer, Janos Porszasz, Harry Rossiter, William Stringer, Michael E. DeBakey, Amir Sharafkhaneh, Charlie Lan, Christine Wendt, Brian Bell, Marilyn G. Foreman, Eugene Berkowitz, Gloria Westney, Russell Bowler, David A. Lynch, Richard Rosiello, David Pace, Gerard Criner, David Ciccolella, Francis Cordova, Chandra Dass, Gilbert D’Alonzo, Parag Desai, Michael Jacobs, Steven Kelsen, Victor Kim, James Mamary, Nathaniel Marchetti, Aditi Satti, Kartik Shenoy, Alex Swift, Irene Swift, Maria Elena Vega-Sanchez, Mark Dransfield, William Bailey, Surya Bhatt, Anand Iyer, Hrudaya Nath, J. Michael Wells, Joe Ramsdell, Paul Friedman, Xavier Soler, Andrew Yen, Alejandro P. Comellas, Karin F. Hoth, John Newell Jr, Brad Thompson, Mei Lan K. Han, Ella Kazerooni, Carlos H. Martinez, Joanne Billings, Abbie Begnaud, Tadashi Allen, Frank Sciurba, Jessica Bon, Divay Chandra, Carl Fuhrman, Joel Weissfeld, Antonio Anzueto, Sandra Adams, Diego Maselli-Caceres, Mario E. Ruiz
The utility of biomarkers in diagnosis of aspirin exacerbated respiratory disease
Suzy A. A. Comhair, Grazyna Bochenek, Sara Baicker-McKee, Zeneng Wang, Tomasz Stachura, Marek Sanak, Jeffrey P. Hammel, Stanley L. Hazen, Serpil C. Erzurum, Ewa Nizankowska-Mogilnicka
Dietary ω-6 polyunsaturated fatty acid arachidonic acid increases inflammation, but inhibits ECM protein expression in COPD
Sandra Rutting, Michael Papanicolaou, Dia Xenaki, Lisa G. Wood, Alexander M. Mullin, Philip M. Hansbro, Brian G. Oliver
From blood to lung tissue: effect of cigarette smoke on DNA methylation and lung function
Maaike de Vries, Diana A van der Plaat, Ivana Nedeljkovic, Rikst Nynke Verkaik-Schakel, Wierd Kooistra, Najaf Amin, Cornelia M van Duijn, Corry-Anke Brandsma, Cleo C van Diemen, Judith M Vonk, H Marike Boezen
Quantitative CT analysis using functional imaging is superior in describing disease progression in idiopathic pulmonary fibrosis compared to forced vital capacity
J. Clukers, M. Lanclus, B. Mignot, C. Van Holsbeke, J. Roseman, S. Porter, E. Gorina, E. Kouchakji, K. E. Lipson, W. De Backer, J. De Backer
Association of lung function with cardiovascular risk: a cohort study
Bin Wang, Yun Zhou, Lili Xiao, Yanjun Guo, Jixuan Ma, Min Zhou, Tingming Shi, Aijun Tan, Jing Yuan, Weihong Chen
Serum AGE/RAGEs as potential biomarker in idiopathic pulmonary fibrosis
Carlos Machahua, Ana Montes-Worboys, Lurdes Planas-Cerezales, Raquel Buendia-Flores, Maria Molina-Molina, Vanesa Vicens-Zygmunt
Right heart size and function significantly correlate in patients with pulmonary arterial hypertension – a cross-sectional study
Lukas Fischer, Nicola Benjamin, Norbert Blank, Benjamin Egenlauf, Christine Fischer, Satenik Harutyunova, Maria Koegler, Hanns-Martin Lorenz, Alberto M. Marra, Christian Nagel, Panagiota Xanthouli, Eduardo Bossone, Ekkehard Grünig
Efficacy and safety of antagonists for chemoattractant receptor-homologous molecule expressed on Th2 cells in adult patients with asthma: a meta-analysis and systematic review
Jing Yang, Jian Luo, Ling Yang, Dan Yang, Dan Wang, Bicui Liu, Tingxuan Huang, Xiaohu Wang, Binmiao Liang, Chuntao Liu
Therapeutic potential of products derived from mesenchymal stem/stromal cells in pulmonary disease
Arezoo Mohammadipoor, Ben Antebi, Andriy I. Batchinsky, Leopoldo C. Cancio
Primary immunodeficiency diseases in lung disease: warning signs, diagnosis and management
Pere Soler-Palacín, Javier de Gracia, Luis Ignacio González-Granado, Carlos Martín, Carlos Rodríguez-Gallego, Silvia Sánchez-Ramón, Lung ID-Signal Group
Unfractionated heparin ameliorates pulmonary microvascular endothelial barrier dysfunction via microtubule stabilization in acute lung injury
Shengtian Mu, Yina Liu, Jing Jiang, Renyu Ding, Xu Li, Xin Li, Xiaochun Ma
Role of SOD3 in silica-related lung fibrosis and pulmonary vascular remodeling
Igor N. Zelko, Jianxin Zhu, Jesse Roman
Long-term outcomes following first short-term clinically important deterioration in COPD
Ian P. Naya, Lee Tombs, Hana Muellerova, Christopher Compton, Paul W. Jones
Heterogeneous burden of lung disease in smokers with borderline airflow obstruction
Cheryl S. Pirozzi, Tian Gu, Pedro M. Quibrera, Elizabeth E. Carretta, MeiLan K. Han, Susan Murray, Christopher B. Cooper, Donald P. Tashkin, Eric C. Kleerup, Igor Barjaktarevic, Eric A. Hoffman, Carlos H. Martinez, Stephanie A. Christenson, Nadia N. Hansel, R. Graham Barr, Eugene R. Bleecker, Victor E. Ortega, Fernando J. Martinez, Richard E. Kanner, Robert Paine III, Neil E. Alexis, Wayne H. Anderson, R. Graham Barr, Eugene R. Bleecker, Richard C. Boucher, Russell P. Bowler, Elizabeth E. Carretta, Stephanie A. Christenson, Alejandro P. Comellas, Christopher B. Cooper, David J. Couper, Gerard J. Criner, Ronald G. Crystal, Jeffrey L. Curtis, Claire M. Doerschuk, Mark T. Dransfield, Christine M. Freeman, MeiLan Lan K. Han, Nadia N. Hansel, Annette T. Hastie, Eric A. Hoffman, Robert J. Kaner, Richard E. Kanner, Eric C. Kleerup, Jerry A. Krishnan, Lisa M. LaVange, Stephen C. Lazarus, Fernando J. Martinez, Deborah A. Meyers, John D. Newell Jr, Elizabeth C. Oelsner, Wanda K. O’Neal, Robert Paine III, Nirupama Putcha, Stephen I. Rennard, Donald P. Tashkin, Mary Beth Scholand, J. Michael Wells, Robert A. Wise, Prescott G. Woodruff, Lisa Postow, Thomas Croxton
Cost-effectiveness analysis of umeclidinium bromide/vilanterol 62.5/25 mcg versus tiotropium/olodaterol 5/5 mcg in symptomatic patients with chronic obstructive pulmonary disease: a Spanish National Healthcare System perspective
M. T. Driessen, J. Whalen, B. Seewoodharry Buguth, L. A. Vallejo-Aparicio, I. P. Naya, Y. Asukai, B. Alcázar-Navarrete, M. Miravitlles, F. García-Río, N. A. Risebrough
Combination of inspiratory and expiratory muscle training in same respiratory cycle versus different cycles in COPD patients: a randomized trial
Wenhui Xu, Rui Li, Lili Guan, Kai Wang, Yuhe Hu, Limei Xu, Luqian Zhou, Rongchang Chen, Xin Chen
MUC1 deficiency mediates corticosteroid resistance in chronic obstructive pulmonary disease
Javier Milara, Lucía Díaz-Platas, Sonia Contreras, Pilar Ribera, Inés Roger, Beatriz Ballester, Paula Montero, Ángel Cogolludo, Esteban Morcillo, Julio Cortijo
Nebulization versus standard application for topical anaesthesia during flexible bronchoscopy under moderate sedation – a randomized controlled trial
Tobias Müller, Christian Cornelissen, Michael Dreher
Influence of viral infection on the relationships between airway cytokines and lung function in asthmatic children
Toby C. Lewis, Ediri E. Metitiri, Graciela B. Mentz, Xiaodan Ren, Ashley R. Carpenter, Adam M. Goldsmith, Kyra E. Wicklund, Breanna N. Eder, Adam T. Comstock, Jeannette M. Ricci, Sean R. Brennan, Ginger L. Washington, Kendall B. Owens, Bhramar Mukherjee, Thomas G. Robins, Stuart A. Batterman, Marc B. Hershenson
Alterations in VASP phosphorylation and profilin1 and cofilin1 expression in hyperoxic lung injury and BPD
Mehboob Ali, Kathryn Heyob, Trent E. Tipple, Gloria S. Pryhuber, Lynette K. Rogers
Roles of mitochondrial ROS and NLRP3 inflammasome in multiple ozone-induced lung inflammation and emphysema
Feng Li, Mengmeng Xu, Muyun Wang, Lei Wang, Hanying Wang, Hai Zhang, Yuqing Chen, Jicheng Gong, Junfeng(Jim) Zhang, Ian M. Adcock, Kian Fan Chung, Xin Zhou
Inflammation and lung injury in an ovine model of fluid resuscitated endotoxemic shock
Margaret R. Passmore, Liam Byrne, Nchafatso G. Obonyo, Louise E. See Hoe, Ai-Ching Boon, Sara D. Diab, Kimble R. Dunster, Kavita Bisht, John-Paul Tung, Mohd H. Fauzi, Monica Narula, Sanne E. Pedersen, Arlanna Esguerra-Lallen, Gabriela Simonova, Annette Sultana, Chris M. Anstey, Kiran Shekar, Kathryn Maitland, Jacky Y. Suen, John F. Fraser
Thank you and farewell after 15 years editing Respiratory Research
Jan Lotvall, Reynold A. Panettieri Jr
Inflammatory pathways are upregulated in the nasal epithelium in patients with idiopathic pulmonary fibrosis
Marc A. Sala, Yalbi Itzel Balderas-Martínez, Ivette Buendía-Roldan, Hiam Abdala-Valencia, Kiwon Nam, Manu Jain, Sangeeta Bhorade, Ankit Bharat, Paul A. Reyfman, Karen M. Ridge, Annie Pardo, Jacob I. Sznajder, G. R. Scott Budinger, Alexander V. Misharin, Moises Selman
Airway epithelial cells exposed to wildfire smoke extract exhibit dysregulated autophagy and barrier dysfunction consistent with COPD
Eugene Roscioli, Rhys Hamon, Susan E. Lester, Hubertus P. A. Jersmann, Paul N. Reynolds, Sandra Hodge
Downregulation of exosomal let-7a-5p in dust exposed- workers contributes to lung cancer development
Lin Zhang, Changfu Hao, Ruonan Zhai, Di Wang, Jianhui Zhang, Lei Bao, Yiping Li, Wu Yao
Soluble epoxide hydrolase derived lipid mediators are elevated in bronchoalveolar lavage fluid from patients with sarcoidosis: a cross-sectional study
Marcus O. D. Sjödin, Antonio Checa, Mingxing Yang, Sven-Erik Dahlén, Åsa M. Wheelock, Anders Eklund, Johan Grunewald, Craig E. Wheelock
Use and inhalation technique of inhaled medication in patients with asthma and COPD: data from a randomized controlled trial
Claudia Gregoriano, Thomas Dieterle, Anna-Lisa Breitenstein, Selina Dürr, Amanda Baum, Sabrina Maier, Isabelle Arnet, Kurt E. Hersberger, Jörg D. Leuppi
Cellular and acellular ex vivo lung perfusion preserve functional lung ultrastructure in a large animal model: a stereological study
Jasmin Steinmeyer, Simon Becker, Murat Avsar, Jawad Salman, Klaus Höffler, Axel Haverich, Gregor Warnecke, Christian Mühlfeld, Matthias Ochs, Anke Schnapper-Isl
Women with COPD by biomass show different serum profile of adipokines, incretins, and peptide hormones than smokers
Oliver Pérez-Bautista, Martha Montaño, Rogelio Pérez-Padilla, Joaquín Zúñiga-Ramos, Mariana Camacho-Priego, Tonatiuh Barrientos-Gutiérrez, Ivette Buendía-Roldan, Yadira Velasco-Torres, Carlos Ramos
Dihydrotestosterone is a predictor for mortality in males with community-acquired pneumonia: results of a 6-year follow-up study
Seline Zurfluh, Manuela Nickler, Manuel Ottiger, Christian Steuer, Alexander Kutz, Mirjam Christ-Crain, Werner Zimmerli, Robert Thomann, Claus Hoess, Christoph Henzen, Luca Bernasconi, Andreas Huber, Beat Mueller, Philipp Schuetz, Ursula Schild, Katharina Regez, Rita Bossart, Robert Thomann, Claudine Falconnier, Marcel Wolbers, Stefanie Neidert, Thomas Fricker, Claudine Blum, Thomas Bregenzer, Claus Hoess, Heiner C. Bucher, Fabian Mueller, Jeannine Haeuptle, Roya Zarbosky, Rico Fiumefreddo, Melanie Wieland, Charly Nusbaumer, Andres Christ, Roland Bingisser, Kristian Schneider, Brigitte Walz, Verena Briner, Dieter Conen, Andreas Huber, Jody Staehelin, Chantal Bruehlhardt, Ruth Luginbuehl, Agnes Muehlemann, Ineke Lambinon, Werner Zimmerli, Max Zueger
SOX30 specially prevents Wnt-signaling to suppress metastasis and improve prognosis of lung adenocarcinoma patients
Fei Han, Ming-qian Zhang, Wen-bin Liu, Lei Sun, Xiang-lin Hao, Li Yin, Xiao Jiang, Jia Cao, Jin-yi Liu
Pneumonia in patients with cirrhosis: risk factors associated with mortality and predictive value of prognostic models
Lichen Xu, Shuangwei Ying, Jianhua Hu, Yunyun Wang, Meifang Yang, Tiantian Ge, Chunhong Huang, Qiaomai Xu, Haihong Zhu, Zhi Chen, Weihang Ma
Lipoxin A4 receptor agonist BML-111 induces autophagy in alveolar macrophages and protects from acute lung injury by activating MAPK signaling
Huaizheng Liu, Kefu Zhou, Liangkan Liao, Tianyi Zhang, Mingshi Yang, Chuanzheng Sun
Cytotoxic lymphocytes in COPD airways: increased NK cells associated with disease, iNKT and NKT-like cells with current smoking
Jonas Eriksson Ström, Jamshid Pourazar, Robert Linder, Anders Blomberg, Anne Lindberg, Anders Bucht, Annelie F. Behndig
Microbial dysbiosis and mortality during mechanical ventilation: a prospective observational study
Daphnée Lamarche, Jennie Johnstone, Nicole Zytaruk, France Clarke, Lori Hand, Dessi Loukov, Jake C. Szamosi, Laura Rossi, Louis P. Schenck, Chris P. Verschoor, Ellen McDonald, Maureen O. Meade, John C. Marshall, Dawn M. E. Bowdish, Tim Karachi, Diane Heels-Ansdell, Deborah J. Cook, Michael G. Surette
The impact of outdoor air pollutants on outpatient visits for respiratory diseases during 2012–2016 in Jinan, China
Shanshan Wang, Yifan Li, Aimin Niu, Yao Liu, Lili Su, Wanmei Song, Jinyue Liu, Yunxia Liu, Huaichen Li
Pleural effusion as an initial manifestation in a patient with primary pulmonary monoclonal B-cell lymphocyte proliferative disease
Qin Du, Lili Fan, Hongyu Zhou
Identification of deleterious and regulatory genomic variations in known asthma loci
Matthew D. C. Neville, Jihoon Choi, Jonathan Lieberman, Qing Ling Duan
The effect of changes to GOLD severity stage on long term morbidity and mortality in COPD
Robert W. V. Flynn, Thomas M. MacDonald, James D. Chalmers, Stuart Schembri
GLI 2012 equations define few spirometric anomalies in the general population: the PneumoLaus study
Alexandra Lenoir, Jean-William Fitting, Pedro-Manuel Marques-Vidal, Peter Vollenweider, Laurent P. Nicod
Spirometric changes during exacerbations of COPD: a post hoc analysis of the WISDOM trial
Henrik Watz, Kay Tetzlaff, Helgo Magnussen, Achim Mueller, Roberto Rodriguez-Roisin, Emiel F. M. Wouters, Claus Vogelmeier, Peter M. A. Calverley
Effects of smoking on the lower respiratory tract microbiome in mice
Rui Zhang, Ling Chen, Lei Cao, Kang-jie Li, Yao Huang, Xiao-qian Luan, Ge Li
LncRNA H19 promotes the proliferation of pulmonary artery smooth muscle cells through AT1R via sponging let-7b in monocrotaline-induced pulmonary arterial hypertension
Hua Su, Xiaoling Xu, Chao Yan, Yangfeng Shi, Yanjie Hu, Liangliang Dong, Songmin Ying, Kejing Ying, Ruifeng Zhang
Pulmonary aspiration in preschool children with cystic fibrosis
D. Clarke, I. Gorman, F. Ringholz, M. McDermott, DW. Cox, P. Greally, B. Linnane, P. Mc Nally
Predictors of clinical response to extrafine and non-extrafine particle inhaled corticosteroids in smokers and ex-smokers with asthma
Fajri Gafar, Ilse M. Boudewijn, Claire A. Cox, Judith M. Vonk, Siebrig Schokker, Anne J. Lexmond, Henderik W. Frijlink, Paul Hagedoorn, Dirkje S. Postma, Maarten van den Berge
Centrilobular emphysema and coronary artery calcification: mediation analysis in the SPIROMICS cohort
Surya P. Bhatt, Hrudaya P. Nath, Young-il Kim, Rekha Ramachandran, Jubal R. Watts, Nina L. J. Terry, Sushil Sonavane, Swati P. Deshmane, Prescott G. Woodruff, Elizabeth C. Oelsner, Sandeep Bodduluri, MeiLan K. Han, Wassim W. Labaki, J. Michael Wells, Fernando J. Martinez, R. Graham Barr, Mark T. Dransfield, Neil E. Alexis, Wayne H. Anderson, Eugene R. Bleecker, Richard C. Boucher, Russell P. Bowler, Elizabeth E. Carretta, Stephanie A. Christenson, Alejandro P. Comellas, Christopher B. Cooper, David J. Couper, Gerard J. Criner, Ronald G. Crystal, Jeffrey L. Curtis, Claire M. Doerschuk, Christine M. Freeman, Nadia N. Hansel, Annette T. Hastie, Eric A. Hoffman, Robert J. Kaner, Richard E. Kanner, Eric C. Kleerup, Jerry A. Krishnan, Lisa M. LaVange, Stephen C. Lazarus, Deborah A. Meyers, Wendy C. Moore, John D. Newell Jr, Laura Paulin, Stephen Peters, Wanda K. O’Neal, Victor E. Ortega, Robert Paine III, Nirupama Putcha, Stephen I. Rennard, Donald P. Tashkin, Mary Beth Scholand, J. Michael Wells, Robert A. Wise
Right ventricular size and function under riociguat in pulmonary arterial hypertension and chronic thromboembolic pulmonary hypertension (the RIVER study)
Alberto M. Marra, Michael Halank, Nicola Benjamin, Eduardo Bossone, Antonio Cittadini, Christina A. Eichstaedt, Benjamin Egenlauf, Satenik Harutyunova, Christine Fischer, Henning Gall, Hossein Ardeschir Ghofrani, Marius M. Hoeper, Tobias J. Lange, Karen M. Olsson, Hans Klose, Ekkehard Grünig
Impact of Mycobacterium tuberculosis complex lineages as a determinant of disease phenotypes from an immigrant rich moderate tuberculosis burden country
Bright Varghese, Mushira Enani, Abdulrahman Alrajhi, Sameera Al Johani, Ali Albarak, Sahar Althawadi, Noura Elkhizzi, Hawra AlGhafli, Mohammed Shoukri, Sahal Al - Hajoj
Healthier without healthcare? The paradox of the common cold
Daniele de Luca, Oliver Schildgen
Clinical variables predicting the risk of a hospital stay for longer than 7 days in patients with severe acute exacerbations of chronic obstructive pulmonary disease: a prospective study
Ernesto Crisafulli, Antonella Ielpo, Enric Barbeta, Adrian Ceccato, Arturo Huerta, Albert Gabarrús, Néstor Soler, Alfredo Chetta, Antoni Torres
Investigating the mechanism by which SMAD3 induces PAX6 transcription to promote the development of non-small cell lung cancer
Zhe Qian, Qiankun Zhang, Ying Hu, Tongmei Zhang, Jie Li, Zan Liu, Hua Zheng, Yuan Gao, Wenyun Jia, Aimin Hu, Baolan Li, Jiqing Hao