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Zeitschrift

Critical Care

Critical Care 1/2018

Ausgabe 1/2018

Inhaltsverzeichnis ( 359 Artikel )

01.12.2018 | Viewpoint | Ausgabe 1/2018 Open Access

ICU-acquired weakness: should medical sovereignty belong to any specialist?

Domenico Intiso

01.12.2018 | Letter | Ausgabe 1/2018 Open Access

Developing a feasible and valid scoring system for critically ill patients in resource-limited settings

Gentle Sunder Shrestha

01.12.2018 | Research | Ausgabe 1/2018 Open Access

High frequency percussive ventilation increases alveolar recruitment in early acute respiratory distress syndrome: an experimental, physiological and CT scan study

Thomas Godet, Matthieu Jabaudon, Raïko Blondonnet, Aymeric Tremblay, Jules Audard, Benjamin Rieu, Bruno Pereira, Jean-Marc Garcier, Emmanuel Futier, Jean-Michel Constantin

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Cost-effectiveness study of early versus late parenteral nutrition in critically ill children (PEPaNIC): preplanned secondary analysis of a multicentre randomised controlled trial

Esther van Puffelen, Suzanne Polinder, Ilse Vanhorebeek, Pieter Jozef Wouters, Niek Bossche, Guido Peers, Sören Verstraete, Koen Felix Maria Joosten, Greet Van den Berghe, Sascha Cornelis Antonius Theodorus Verbruggen, Dieter Mesotten

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Incidence, risk factors and impact of protocolised care on exposure keratopathy in critically ill adults: a two-phase prospective cohort study

Obaid Kousha, Zubaid Kousha, Jonathan Paddle

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Tracheal intubation in critically ill patients: a comprehensive systematic review of randomized trials

Luca Cabrini, Giovanni Landoni, Martina Baiardo Redaelli, Omar Saleh, Carmine D. Votta, Evgeny Fominskiy, Alessandro Putzu, Cézar Daniel Snak de Souza, Massimo Antonelli, Rinaldo Bellomo, Paolo Pelosi, Alberto Zangrillo

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Global trends in the awareness of sepsis: insights from search engine data between 2012 and 2017

Craig S. Jabaley, James M. Blum, Robert F. Groff, Vikas N. O’Reilly-Shah

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Determinants of long-term outcome in ICU survivors: results from the FROG-ICU study

Etienne Gayat, Alain Cariou, Nicolas Deye, Antoine Vieillard-Baron, Samir Jaber, Charles Damoisel, Qin Lu, Xavier Monnet, Isabelle Rennuit, Elie Azoulay, Marc Léone, Heikel Oueslati, Bertrand Guidet, Diane Friedman, Antoine Tesnière, Romain Sonneville, Philippe Montravers, Sébastien Pili-Floury, Jean-Yves Lefrant, Jacques Duranteau, Pierre-François Laterre, Nicolas Brechot, Karine Chevreul, Morgane Michel, Bernard Cholley, Matthieu Legrand, Jean-Marie Launay, Eric Vicaut, Mervyn Singer, Matthieu Resche-Rigon, Alexandre Mebazaa

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Emergency department hyperoxia is associated with increased mortality in mechanically ventilated patients: a cohort study

David Page, Enyo Ablordeppey, Brian T. Wessman, Nicholas M. Mohr, Stephen Trzeciak, Marin H. Kollef, Brian W. Roberts, Brian M. Fuller

01.12.2018 | Viewpoint | Ausgabe 1/2018 Open Access

The apelinergic system as an alternative to catecholamines in low-output septic shock

David Coquerel, Xavier Sainsily, Lauralyne Dumont, Philippe Sarret, Éric Marsault, Mannix Auger-Messier, Olivier Lesur

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Glycaemic control targets after traumatic brain injury: a systematic review and meta-analysis

Jeroen Hermanides, Mark P. Plummer, Mark Finnis, Adam M. Deane, Jonathan P. Coles, David K. Menon

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Supplemental parenteral nutrition versus usual care in critically ill adults: a pilot randomized controlled study

Emma J. Ridley, Andrew R. Davies, Rachael Parke, Michael Bailey, Colin McArthur, Lyn Gillanders, D. James Cooper, Shay McGuinness, for the Supplemental Parenteral Nutrition Clinical Investigators

01.12.2018 | Research | Ausgabe 1/2018 Open Access

An attenuated rate of leg muscle protein depletion and leg free amino acid efflux over time is seen in ICU long-stayers

Lena Gamrin-Gripenberg, Martin Sundström-Rehal, Daniel Olsson, Jonathan Grip, Jan Wernerman, Olav Rooyackers

01.12.2018 | Review | Ausgabe 1/2018 Open Access

Perioperative fluid management in kidney transplantation: a black box

Maria Helena Calixto Fernandes, Thomas Schricker, Sheldon Magder, Roupen Hatzakorzian

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Serum suPAR and syndecan-4 levels predict severity of community-acquired pneumonia: a prospective, multi-centre study

Qiongzhen Luo, Pu Ning, Yali Zheng, Ying Shang, Bing Zhou, Zhancheng Gao

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Cerebral metabolic effects of strict versus conventional glycaemic targets following severe traumatic brain injury

Mark P. Plummer, Natalia Notkina, Ivan Timofeev, Peter J. Hutchinson, Mark E. Finnis, Arun K. Gupta

01.12.2018 | Commentary | Ausgabe 1/2018 Open Access

Do we need new trials of procalcitonin-guided antibiotic therapy?

Thiago Lisboa, Jorge Salluh, Pedro Povoa

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Performance of critical care prognostic scoring systems in low and middle-income countries: a systematic review

Rashan Haniffa, Ilhaam Isaam, A. Pubudu De Silva, Arjen M. Dondorp, Nicolette F. De Keizer

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Transfers from intensive care unit to hospital ward: a multicentre textual analysis of physician progress notes

Kyla N. Brown, Jeanna Parsons Leigh, Hasham Kamran, Sean M. Bagshaw, Rob A. Fowler, Peter M. Dodek, Alexis F. Turgeon, Alan J. Forster, Francois Lamontagne, Andrea Soo, Henry T. Stelfox

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Stress ulcer prophylaxis in intensive care unit patients receiving enteral nutrition: a systematic review and meta-analysis

Hui-Bin Huang, Wei Jiang, Chun-Yao Wang, Han-Yu Qin, Bin Du

01.12.2018 | Letter | Ausgabe 1/2018 Open Access

Breaking the rules: is it the neurointensivists’ turn?

Paolo Gritti, Oluwaseun Akeju, Ferdinando Luca Lorini, Andrea Lanterna, Carlo Brembilla, Federico Bilotta

01.12.2018 | Editorial | Ausgabe 1/2018 Open Access

Doctor—your septic patients have scurvy!

Paul E. Marik, Michael H. Hooper

01.12.2018 | Editorial | Ausgabe 1/2018 Open Access

Animal-assisted intervention in the ICU: a tool for humanization

Megan M. Hosey, Janice Jaskulski, Stephen T. Wegener, Linda L. Chlan, Dale M. Needham

01.12.2018 | Letter | Ausgabe 1/2018 Open Access

Back-to-back comparison of penKID with NephroCheck® to predict acute kidney injury at admission in intensive care unit: a brief report

Etienne Gayat, Cyril Touchard, Alexa Hollinger, Antoine Vieillard-Baron, Alexandre Mebazaa, Matthieu Legrand, on behalf of the FROG ICU study investigators

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Pharmacokinetics of meropenem in septic patients on sustained low-efficiency dialysis: a population pharmacokinetic study

Stephan Braune, Christina König, Jason A. Roberts, Axel Nierhaus, Oliver Steinmetz, Michael Baehr, Stefan Kluge, Claudia Langebrake

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Variation of poorly ventilated lung units (silent spaces) measured by electrical impedance tomography to dynamically assess recruitment

Savino Spadaro, Tommaso Mauri, Stephan H. Böhm, Gaetano Scaramuzzo, Cecilia Turrini, Andreas D. Waldmann, Riccardo Ragazzi, Antonio Pesenti, Carlo Alberto Volta

01.12.2018 | Editorial | Ausgabe 1/2018 Open Access

To eat or to breathe? The answer is both! Nutritional management during noninvasive ventilation

Pierre Singer, Sornwichate Rattanachaiwong

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Performance of the quick Sequential (sepsis-related) Organ Failure Assessment score as a prognostic tool in infected patients outside the intensive care unit: a systematic review and meta-analysis

Jae-Uk Song, Cheol Kyung Sin, Hye Kyeong Park, Sung Ryul Shim, Jonghoo Lee

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Pre-hospital transthoracic echocardiography for early identification of non-ST-elevation myocardial infarction in patients with acute coronary syndrome

Ingo Bergmann, Benedikt Büttner, Elena Teut, Claudius Jacobshagen, José Hinz, Michael Quintel, Ashham Mansur, Markus Roessler

01.12.2018 | Letter | Ausgabe 1/2018 Open Access

Comparing fiberoptic bronchoscopy- and a tracheal tube-mounted camera-guided percutaneous dilatational tracheostomy

Fu-Shan Xue, Chao Wen, Ya-Yang Liu

01.12.2018 | Letter | Ausgabe 1/2018 Open Access

Trustworthy or flawed clinical prediction rule?

Anders Granholm, Anders Perner, Aksel Karl Georg Jensen, Morten Hylander Møller

01.12.2018 | Research | Ausgabe 1/2018 Open Access

End-expiratory occlusion maneuver to predict fluid responsiveness in the intensive care unit: an echocardiographic study

Delphine Georges, Hugues de Courson, Romain Lanchon, Musa Sesay, Karine Nouette-Gaulain, Matthieu Biais

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Copeptin levels and commonly used laboratory parameters in hospitalised patients with severe hypernatraemia - the “Co-MED study”

Nicole Nigro, Bettina Winzeler, Isabelle Suter-Widmer, Philipp Schuetz, Birsen Arici, Martina Bally, Julie Refardt, Matthias Betz, Gani Gashi, Sandrine A. Urwyler, Lukas Burget, Claudine A. Blum, Andreas Bock, Andreas Huber, Beat Müller, Mirjam Christ-Crain

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Prevalence and outcome of patients with non-ST segment elevation myocardial infarction with occluded “culprit” artery – a systemic review and meta-analysis

Chi-Sheng Hung, Ying-Hsien Chen, Ching-Chang Huang, Mao-Shin Lin, Chih-Fan Yeh, Hung-Yuan Li, Hsien-Li Kao

01.12.2018 | Commentary | Ausgabe 1/2018 Open Access

Cardiac output monitoring: throw it out… or keep it?

Xavier Monnet, Jean-Louis Teboul

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Transcranial Doppler combined with quantitative EEG brain function monitoring and outcome prediction in patients with severe acute intracerebral hemorrhage

Ying Chen, Weihai Xu, Lijuan Wang, Xiaoming Yin, Jie Cao, Fang Deng, Yingqi Xing, Jiachun Feng

01.12.2018 | Editorial | Ausgabe 1/2018 Open Access

Hypertonic saline infusion for treating intracranial hypertension after severe traumatic brain injury

Halinder S. Mangat

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Leukocyte telomere length in paediatric critical illness: effect of early parenteral nutrition

Sören Verstraete, Ilse Vanhorebeek, Esther van Puffelen, Inge Derese, Catherine Ingels, Sascha C. Verbruggen, Pieter J. Wouters, Koen F. Joosten, Jan Hanot, Gonzalo G. Guerra, Dirk Vlasselaers, Jue Lin, Greet Van den Berghe

01.12.2018 | Research | Ausgabe 1/2018 Open Access

The practice of intensive care in Latin America: a survey of academic intensivists

Ricardo Castro, Nicolas Nin, Fernando Ríos, Leyla Alegría, Elisa Estenssoro, Gastón Murias, Gilberto Friedman, Manuel Jibaja, Gustavo Ospina-Tascon, Javier Hurtado, María del Carmen Marín, Flavia R. Machado, Alexandre Biasi Cavalcanti, Arnaldo Dubin, Luciano Azevedo, Maurizio Cecconi, Jan Bakker, Glenn Hernandez, On behalf of the Latin-American Intensive Care Network - LIVEN (www.redliven.org)

01.12.2018 | Editorial | Ausgabe 1/2018 Open Access

What is new in critical care echocardiography?

Philippe Vignon

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Interventions to prevent hemodynamic instability during renal replacement therapy in critically ill patients: a systematic review

Adrianna Douvris, Gurpreet Malhi, Swapnil Hiremath, Lauralyn McIntyre, Samuel A. Silver, Sean M. Bagshaw, Ron Wald, Claudio Ronco, Lindsey Sikora, Catherine Weber, Edward G. Clark

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Protracted immune disorders at one year after ICU discharge in patients with septic shock

Florence Riché, Benjamin G. Chousterman, Patrice Valleur, Alexandre Mebazaa, Jean-Marie Launay, Etienne Gayat

01.12.2018 | Viewpoint | Ausgabe 1/2018 Open Access

Should we measure the central venous pressure to guide fluid management? Ten answers to 10 questions

Daniel De Backer, Jean-Louis Vincent

01.12.2018 | Viewpoint | Ausgabe 1/2018 Open Access

The curse of angiopoietin-2 in ARDS: on stranger TI(E)des

Philipp Kümpers, Alexander Lukasz

01.12.2018 | Review | Ausgabe 1/2018 Open Access

Hemodynamic effects of acute hyperoxia: systematic review and meta-analysis

Bob Smit, Yvo M. Smulders, Johannes C. van der Wouden, Heleen M. Oudemans-van Straaten, Angelique M. E. Spoelstra-de Man

01.12.2018 | Editorial | Ausgabe 1/2018 Open Access

Artificial oxygen carriers: a new future?

Donat R. Spahn

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Prognosis of patients excluded by the definition of septic shock based on their lactate levels after initial fluid resuscitation: a prospective multi-center observational study

Byuk Sung Ko, Kyuseok Kim, Sung-Hyuk Choi, Gu Hyun Kang, Tae Gun Shin, You Hwan Jo, Seung Mok Ryoo, Jin Ho Beom, Woon Yong Kwon, Kap Su Han, Han Sung Choi, Sung Phil Chung, Gil Joon Suh, Tae Ho Lim, Won Young Kim, for the Korean Shock Society (KoSS) Investigators

01.12.2018 | Letter | Ausgabe 1/2018 Open Access

Earplugs in the ICU: To sleep, to dream

Edward Litton, Rosalind Elliott, Kelly Thompson

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Feasibility and reliability of frailty assessment in the critically ill: a systematic review

Richard J. Pugh, Amy Ellison, Kate Pye, Christian P. Subbe, Chris M. Thorpe, Nazir I. Lone, Andrew Clegg

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Detection of inspiratory recruitment of atelectasis by automated lung sound analysis as compared to four-dimensional computed tomography in a porcine lung injury model

Stefan Boehme, Frédéric P. R. Toemboel, Erik K. Hartmann, Alexander H. Bentley, Oliver Weinheimer, Yang Yang, Tobias Achenbach, Michael Hagmann, Eugenijus Kaniusas, James E. Baumgardner, Klaus Markstaller

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Intraoperative milrinone versus dobutamine in cardiac surgery patients: a retrospective cohort study on mortality

Dorthe Viemose Nielsen, Christian Torp-Pedersen, Regitze Kuhr Skals, Thomas A. Gerds, Zidryne Karaliunaite, Carl-Johan Jakobsen

01.12.2018 | Review | Ausgabe 1/2018 Open Access

Vasoplegia treatments: the past, the present, and the future

Bruno Levy, Caroline Fritz, Elsa Tahon, Audrey Jacquot, Thomas Auchet, Antoine Kimmoun

01.12.2018 | Letter | Ausgabe 1/2018 Open Access

Decision-making in the detection and management of patients with sepsis in resource-limited settings: the importance of clinical examination

Rashan Haniffa, Abigail Beane, Arjen M. Dondorp

01.12.2018 | Letter | Ausgabe 1/2018 Open Access

Feasibility, safety, and utility of bronchoscopy in patients with ARDS while in the prone position

Or Kalchiem-Dekel, Carl B. Shanholtz, Jean Jeudy, Ashutosh Sachdeva, Edward M. Pickering

01.12.2018 | Letter | Ausgabe 1/2018 Open Access

High-frequency percussive ventilation in acute respiratory distress syndrome: knocking at the door but can it be let in?

Herbert Spapen, Jouke De Regt, Viola van Gorp, Patrick M. Honoré

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Increases in inflammatory and CD14dim/CD16pos/CD45pos patrolling monocytes in sepsis: correlation with final outcome

Gabriela Gainaru, Antonios Papadopoulos, Iraklis Tsangaris, Malvina Lada, Evangelos J. Giamarellos-Bourboulis, Aikaterini Pistiki

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Tight glycemic control in critically ill pediatric patients: a systematic review and meta-analysis

Lvlin Chen, Tiangui Li, Fang Fang, Yu Zhang, Andrew Faramand

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Survival benefit of a low ratio of visceral to subcutaneous adipose tissue depends on LDL clearance versus production in sepsis

Joseph G. H. Lee, Kelly R. Genga, Chawika Pisitsak, John H. Boyd, Alex K. K. Leung, James A. Russell, Keith R. Walley

01.12.2018 | Editorial | Ausgabe 1/2018 Open Access

Before the ICU: does emergency room hyperoxia affect outcome?

Martin Wepler, Julien Demiselle, Peter Radermacher, Pierre Asfar, Enrico Calzia

01.12.2018 | Research | Ausgabe 1/2018 Open Access

The preventive effect of antiplatelet therapy in acute respiratory distress syndrome: a meta-analysis

Yingqin Wang, Ming Zhong, Zhichao Wang, Jieqiong Song, Wei Wu, Duming Zhu

01.12.2018 | Letter | Ausgabe 1/2018 Open Access

Global impact of World Sepsis Day on digital awareness of sepsis: an evaluation using Google Trends

Jelmer Savelkoel, Theodora A. M. Claushuis, Tjitske S. R. van Engelen, Luuk J. J. Scheres, W. Joost Wiersinga

01.12.2018 | Letter | Ausgabe 1/2018 Open Access

A novel method of blind bedside placement of postpyloric tubes

Jia-Kui Sun, Xiang Wang, Shou-Tao Yuan

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Neuromuscular blockade is associated with the attenuation of biomarkers of epithelial and endothelial injury in patients with moderate-to-severe acute respiratory distress syndrome

Peter D. Sottile, David Albers, Marc M. Moss

01.12.2018 | Editorial | Ausgabe 1/2018 Open Access

The long sepsis journey in low- and middle-income countries begins with a first step...but on which road?

Arthur Kwizera, Inipavudu Baelani, Mervyn Mer, Niranjan Kissoon, Marcus J. Schultz, Andrew J. Patterson, Ndidiamaka Musa, Joseph Christopher Farmer, Martin W. Dünser, Sepsis in Resource-Limited Settings Workgroup of the Surviving Sepsis Campaign

01.12.2018 | Review | Ausgabe 1/2018 Open Access

Bedside ultrasound to detect central venous catheter misplacement and associated iatrogenic complications: a systematic review and meta-analysis

Jasper M. Smit, Reinder Raadsen, Michiel J. Blans, Manfred Petjak, Peter M. Van de Ven, Pieter R. Tuinman

01.12.2018 | Research | Ausgabe 1/2018 Open Access

The efficacy and safety of pre-hospital cooling after out-of-hospital cardiac arrest: a systematic review and meta-analysis

Patrick J. Lindsay, Danielle Buell, Damon C. Scales

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Impact of nighttime Rapid Response Team activation on outcomes of hospitalized patients with acute deterioration

Shannon M. Fernando, Peter M. Reardon, Sean M. Bagshaw, Damon C. Scales, Kyle Murphy, Jennifer Shen, Peter Tanuseputro, Daren K. Heyland, Kwadwo Kyeremanteng

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Exosomes from patients with septic shock convey miRNAs related to inflammation and cell cycle regulation: new signaling pathways in sepsis?

Juliana Monte Real, Ludmila Rodrigues Pinto Ferreira, Gustavo Henrique Esteves, Fernanda Christtanini Koyama, Marcos Vinícius Salles Dias, João Evangelista Bezerra-Neto, Edécio Cunha-Neto, Flavia Ribeiro Machado, Reinaldo Salomão, Luciano Cesar Pontes Azevedo

01.12.2018 | Review | Ausgabe 1/2018 Open Access

Angiotensin in Critical Care

Anna Hall, Laurence W. Busse, Marlies Ostermann

01.12.2018 | Review | Ausgabe 1/2018 Open Access

Making sense of early high-dose intravenous vitamin C in ischemia/reperfusion injury

Angelique M. E. Spoelstra-de Man, Paul W. G. Elbers, Heleen M. Oudemans-van Straaten

01.12.2018 | Review | Ausgabe 1/2018 Open Access

A Systematic Review of the High-flow Nasal Cannula for Adult Patients

Yigal Helviz, Sharon Einav

01.12.2018 | Review | Ausgabe 1/2018 Open Access

Close down the lungs and keep them resting to minimize ventilator-induced lung injury

Paolo Pelosi, Patricia Rieken Macedo Rocco, Marcelo Gama de Abreu

01.12.2018 | Review | Ausgabe 1/2018 Open Access

Diaphragm dysfunction during weaning from mechanical ventilation: an underestimated phenomenon with clinical implications

Martin Dres, Alexandre Demoule

01.12.2018 | Review | Ausgabe 1/2018 Open Access

Effects of Fluids on the Macro- and Microcirculations

Victoria A. Bennett, Alexander Vidouris, Maurizio Cecconi

01.12.2018 | Review | Ausgabe 1/2018 Open Access

Continuous Electroencephalography Monitoring in Adults in the Intensive Care Unit

Anselmo Caricato, Isabella Melchionda, Massimo Antonelli

01.12.2018 | Review | Ausgabe 1/2018 Open Access

Respiratory Management in Patients with Severe Brain Injury

Karim Asehnoune, Antoine Roquilly, Raphaël Cinotti

01.12.2018 | Review | Ausgabe 1/2018 Open Access

Early Mobilization of Patients in Intensive Care: Organization, Communication and Safety Factors that Influence Translation into Clinical Practice

Carol L. Hodgson, Elizabeth Capell, Claire J. Tipping

01.12.2018 | Review | Ausgabe 1/2018 Open Access

The emerging role of the microbiota in the ICU

Nora Suzanne Wolff, Floor Hugenholtz, Willem Joost Wiersinga

01.12.2018 | Research | Ausgabe 1/2018 Open Access

The use of mid-regional proadrenomedullin to identify disease severity and treatment response to sepsis - a secondary analysis of a large randomised controlled trial

Gunnar Elke, Frank Bloos, Darius Cameron Wilson, Frank Martin Brunkhorst, Josef Briegel, Konrad Reinhart, Markus Loeffler, Stefan Kluge, Axel Nierhaus, Ulrich Jaschinski, Onnen Moerer, Andreas Weyland, Patrick Meybohm, the SepNet Critical Care Trials Group

01.12.2018 | Review | Ausgabe 1/2018 Open Access

Acute exacerbation of idiopathic pulmonary fibrosis: lessons learned from acute respiratory distress syndrome?

Alessandro Marchioni, Roberto Tonelli, Lorenzo Ball, Riccardo Fantini, Ivana Castaniere, Stefania Cerri, Fabrizio Luppi, Mario Malerba, Paolo Pelosi, Enrico Clini

01.12.2018 | Review | Ausgabe 1/2018 Open Access

Renal autoregulation and blood pressure management in circulatory shock

Emiel Hendrik Post, Jean-Louis Vincent

01.12.2018 | Letter | Ausgabe 1/2018 Open Access

Do we need new trials of procalcitonin-guided antibiotic therapy? A response

Jos A. H. van Oers, Maarten W. Nijsten, Dylan W. de Lange

01.12.2018 | Letter | Ausgabe 1/2018 Open Access

Comparing fiberoptic bronchoscopy and a tracheal tube-mounted camera-guided percutaneous dilatational tracheostomy: authors' reply

Jörn Grensemann, Lars Eichler, Sophie Kähler, Dominik Jarczak, Marcel Simon, Hans O. Pinnschmidt, Stefan Kluge

01.12.2018 | Letter | Ausgabe 1/2018 Open Access

Use of a meta-analysis to assess the preventive effect of dexmedetomidine on cardiac surgery-associated acute kidney injury

Gui-Zhen Yang, Fu-Shan Xue, Ya-Yang Liu

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Indicators of intensive care unit capacity strain: a systematic review

Oleksa G. Rewa, Henry T. Stelfox, Armann Ingolfsson, David A. Zygun, Robin Featherstone, Dawn Opgenorth, Sean M. Bagshaw

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Reverse shock index multiplied by Glasgow Coma Scale score (rSIG) is a simple measure with high discriminant ability for mortality risk in trauma patients: an analysis of the Japan Trauma Data Bank

Akio Kimura, Noriko Tanaka

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Diagnostic and management of life-threatening Adult-Onset Still Disease: a French nationwide multicenter study and systematic literature review

Antoine Néel, Anaïs Wahbi, Benoit Tessoulin, Julien Boileau, Dorothée Carpentier, Olivier Decaux, Laurence Fardet, Guillaume Geri, Pascal Godmer, Cécile Goujard, Hervé Maisonneuve, Arnaud Mari, Jacques Pouchot, Jean-Marc Ziza, Cédric Bretonnière, Mohamed Hamidou

01.12.2018 | Letter | Ausgabe 1/2018 Open Access

Cardiac output and CVP monitoring… to guide fluid removal

Matthieu Legrand, Sabri Soussi, François Depret

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Variation in general supportive and preventive intensive care management of traumatic brain injury: a survey in 66 neurotrauma centers participating in the Collaborative European NeuroTrauma Effectiveness Research in Traumatic Brain Injury (CENTER-TBI) study

Jilske A. Huijben, Victor Volovici, Maryse C. Cnossen, Iain K. Haitsma, Nino Stocchetti, Andrew I. R. Maas, David K. Menon, Ari Ercole, Giuseppe Citerio, David Nelson, Suzanne Polinder, Ewout W. Steyerberg, Hester F. Lingsma, Mathieu van der Jagt, CENTER-TBI investigators and participants

01.12.2018 | Editorial | Ausgabe 1/2018 Open Access

Route, early or energy? … Protein improves protein balance in critically ill patients

Peter J. M. Weijs

01.12.2018 | Editorial | Ausgabe 1/2018 Open Access

Promoting and sustaining a historical and global effort to prevent sepsis: the 2018 World Health Organization SAVE LIVES: Clean Your Hands campaign

Romain Martischang, Daniela Pires, Sarah Masson-Roy, Hiroki Saito, Didier Pittet

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Epidemiology of sepsis in intensive care units in Turkey: a multicenter, point-prevalence study

Nur Baykara, Halis Akalın, Mustafa Kemal Arslantaş, Volkan Hancı, Çiğdem Çağlayan, Ferda Kahveci, Kubilay Demirağ, Canan Baydemir, Necmettin Ünal, Sepsis Study Group

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Population pharmacokinetics/pharmacodynamics of micafungin against Candida species in obese, critically ill, and morbidly obese critically ill patients

Emilio Maseda, Santiago Grau, Sonia Luque, Maria-Pilar Castillo-Mafla, Alejandro Suárez-de-la-Rica, Ana Montero-Feijoo, Patricia Salgado, Maria-Jose Gimenez, Carlos A. García-Bernedo, Fernando Gilsanz, Jason A. Roberts

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Lymphocyte subset expression and serum concentrations of PD-1/PD-L1 in sepsis - pilot study

Julie K. Wilson, Yuan Zhao, Mervyn Singer, Jo Spencer, Manu Shankar-Hari

01.12.2018 | Letter | Ausgabe 1/2018 Open Access

Angiotensin II for the treatment of vasodilatory shock: enough data to consider angiotensin II safe?

Nina Buchtele, Michael Schwameis, Bernd Jilma

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Association between afterhours admission to the intensive care unit, strained capacity, and mortality: a retrospective cohort study

Adam M. Hall, Henry T. Stelfox, Xioaming Wang, Guanmin Chen, Danny J. Zuege, Peter Dodek, Allan Garland, Damon C. Scales, Luc Berthiaume, David A. Zygun, Sean M. Bagshaw

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Fungal infections in adult patients on extracorporeal life support

Yiorgos Alexandros Cavayas, Hakeem Yusuff, Richard Porter

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Effects of modifiable prehospital factors on survival after out-of-hospital cardiac arrest in rural versus urban areas

Wenche Torunn Mathiesen, Conrad Arnfinn Bjørshol, Jan Terje Kvaløy, Eldar Søreide

01.12.2018 | Research | Ausgabe 1/2018 Open Access

The impact of blood type O on mortality of severe trauma patients: a retrospective observational study

Wataru Takayama, Akira Endo, Hazuki Koguchi, Momoko Sugimoto, Kiyoshi Murata, Yasuhiro Otomo

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Early versus standard initiation of renal replacement therapy in furosemide stress test non-responsive acute kidney injury patients (the FST trial)

Nuttha Lumlertgul, Sadudee Peerapornratana, Thananda Trakarnvanich, Wanjak Pongsittisak, Kajbundit Surasit, Anan Chuasuwan, Pleumjit Tankee, Khajohn Tiranathanagul, Kearkiat Praditpornsilpa, Kriang Tungsanga, Somchai Eiam-Ong, John A. Kellum, Nattachai Srisawat, for the FST Study Group

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Worldwide audit of blood transfusion practice in critically ill patients

Jean-Louis Vincent, Ulrich Jaschinski, Xavier Wittebole, Jean-Yves Lefrant, Stephan M. Jakob, Ghaleb A. Almekhlafi, Tommaso Pellis, Swagata Tripathy, Paolo N. Rubatto Birri, Yasser Sakr, on behalf of the ICON Investigators

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Resuscitative endovascular balloon occlusion of the aorta performed by emergency physicians for traumatic hemorrhagic shock: a case series from Japanese emergency rooms

Ryota Sato, Akira Kuriyama, Rei Takaesu, Nobuhiro Miyamae, Wataru Iwanaga, Hayato Tokuda, Takehiro Umemura

01.12.2018 | Letter | Ausgabe 1/2018 Open Access

Blocking soluble guanylate cyclase could be the present and future of NO/cGMP inhibition for vasoplegia treatment

Paulo Roberto Barbosa Evora

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Evaluation of a real-time PCR assay for detection and quantification of bacterial DNA directly in blood of preterm neonates with suspected late-onset sepsis

Marre van den Brand, Frank A. M. van den Dungen, Martine P. Bos, Mirjam M. van Weissenbruch, A. Marceline van Furth, Annemieke de Lange, Anna Rubenjan, Remco P. H. Peters, Paul H. M. Savelkoul

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Inclusion and definition of acute renal dysfunction in critically ill patients in randomized controlled trials: a systematic review

Rogerio da Hora Passos, Joao Gabriel Rosa Ramos, André Gobatto, Juliana Caldas, Etienne Macedo, Paulo Benigno Batista

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Distinct T-helper cell responses to Staphylococcus aureus bacteremia reflect immunologic comorbidities and correlate with mortality

Jared A. Greenberg, Cara L. Hrusch, Mohammad R. Jaffery, Michael Z. David, Robert S. Daum, Jesse B. Hall, John P. Kress, Anne I. Sperling, Philip A. Verhoef

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Urinary biomarkers predict advanced acute kidney injury after cardiovascular surgery

Jian-Jhong Wang, Nai-Hsin Chi, Tao-Min Huang, Rory Connolly, Liang Wen Chen, Shih-Chieh Jeff Chueh, Wei-Chih Kan, Chih-Cheng Lai, Vin-Cent Wu, Ji-Tseng Fang, Tzong-Shinn Chu, Kwan-Dun Wu

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Ultrasound-assessed diaphragmatic impairment is a predictor of outcomes in patients with acute exacerbation of chronic obstructive pulmonary disease undergoing noninvasive ventilation

Alessandro Marchioni, Ivana Castaniere, Roberto Tonelli, Riccardo Fantini, Matteo Fontana, Luca Tabbì, Andrea Viani, Francesco Giaroni, Valentina Ruggieri, Stefania Cerri, Enrico Clini

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Comparison of exercise intensity during four early rehabilitation techniques in sedated and ventilated patients in ICU: a randomised cross-over trial

Clément Medrinal, Yann Combret, Guillaume Prieur, Aurora Robledo Quesada, Tristan Bonnevie, Francis Edouard Gravier, Elise Dupuis Lozeron, Eric Frenoy, Olivier Contal, Bouchra Lamia

01.12.2018 | Research | Ausgabe 1/2018 Open Access

6% Hydroxyethyl starch (HES 130/0.4) diminishes glycocalyx degradation and decreases vascular permeability during systemic and pulmonary inflammation in mice

Andreas Margraf, Jan M. Herter, Katharina Kühne, Anika Stadtmann, Thomas Ermert, Manuel Wenk, Melanie Meersch, Hugo Van Aken, Alexander Zarbock, Jan Rossaint

01.12.2018 | Review | Ausgabe 1/2018 Open Access

Pathophysiology, echocardiographic evaluation, biomarker findings, and prognostic implications of septic cardiomyopathy: a review of the literature

Robert R. Ehrman, Ashley N. Sullivan, Mark J. Favot, Robert L. Sherwin, Christian A. Reynolds, Aiden Abidov, Phillip D. Levy

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Development and validation of a pre-hospital “Red Flag” alert for activation of intra-hospital haemorrhage control response in blunt trauma

Sophie Rym Hamada, Anne Rosa, Tobias Gauss, Jean-Philippe Desclefs, Mathieu Raux, Anatole Harrois, Arnaud Follin, Fabrice Cook, Mathieu Boutonnet, Arie Attias, Sylvain Ausset, Gilles Dhonneur, Olivier Langeron, Catherine Paugam-Burtz, Romain Pirracchio, Bruno Riou, Guillaume de St Maurice, Bernard Vigué, Alexandra Rouquette, Jacques Duranteau, the Traumabase® Group

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Delirium prediction in the intensive care unit: comparison of two delirium prediction models

Annelies Wassenaar, Lisette Schoonhoven, John W. Devlin, Frank M. P. van Haren, Arjen J. C. Slooter, Philippe G. Jorens, Mathieu van der Jagt, Koen S. Simons, Ingrid Egerod, Lisa D. Burry, Albertus Beishuizen, Joaquim Matos, A. Rogier T. Donders, Peter Pickkers, Mark van den Boogaard

01.12.2018 | Letter | Ausgabe 1/2018 Open Access

Best PEEP trials are dependent on tidal volume

Andrew C. McKown, Matthew W. Semler, Todd W. Rice

01.12.2018 | Commentary | Ausgabe 1/2018 Open Access

Sepsis is a preventable public health problem

Jordan A. Kempker, Henry E. Wang, Greg S. Martin

01.12.2018 | Review | Ausgabe 1/2018 Open Access

Gut–kidney crosstalk in septic acute kidney injury

Jingxiao Zhang, Ghada Ankawi, Jian Sun, Kumar Digvijay, Yongjie Yin, Mitchell H. Rosner, Claudio Ronco

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Haemoglobin concentration and volume of intravenous fluids in septic shock in the ARISE trial

Matthew J. Maiden, Mark E. Finnis, Sandra Peake, Simon McRae, Anthony Delaney, Michael Bailey, Rinaldo Bellomo

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Implications for paediatric shock management in resource-limited settings: a perspective from the FEAST trial

Kirsty Anne Houston, Elizabeth C. George, Kathryn Maitland

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Impact of flow and temperature on patient comfort during respiratory support by high-flow nasal cannula

Tommaso Mauri, Alessandro Galazzi, Filippo Binda, Laura Masciopinto, Nadia Corcione, Eleonora Carlesso, Marta Lazzeri, Elena Spinelli, Daniela Tubiolo, Carlo Alberto Volta, Ileana Adamini, Antonio Pesenti, Giacomo Grasselli

01.12.2018 | Research | Ausgabe 1/2018 Open Access

High-frequency oscillatory ventilation guided by transpulmonary pressure in acute respiratory syndrome: an experimental study in pigs

Philipp Klapsing, Onnen Moerer, Christoph Wende, Peter Herrmann, Michael Quintel, Annalen Bleckmann, Jan Florian Heuer

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Feasibility and safety of low-flow extracorporeal CO2 removal managed with a renal replacement platform to enhance lung-protective ventilation of patients with mild-to-moderate ARDS

Matthieu Schmidt, Samir Jaber, Elie Zogheib, Thomas Godet, Gilles Capellier, Alain Combes

01.12.2018 | Letter | Ausgabe 1/2018 Open Access

Pulmonary vein signal in mitral regurgitation

Tim Balthazar, Bart Jacobs, Jens-Uwe Voigt

01.12.2018 | Review | Ausgabe 1/2018 Open Access

Clinical chronobiology: a timely consideration in critical care medicine

Helen McKenna, Gijsbertus T. J. van der Horst, Irwin Reiss, Daniel Martin

01.12.2018 | Letter | Ausgabe 1/2018 Open Access

Experience of using beta-D-glucan assays in the intensive care unit

A. Dagens, N. Mughal, A. Sisson, L. S. P. Moore

01.12.2018 | Research | Ausgabe 1/2018 Open Access

TIMP-2/IGFBP7 predicts acute kidney injury in out-of-hospital cardiac arrest survivors

Christoph Adler, Tobias Heller, Felix Schregel, Henning Hagmann, Martin Hellmich, Joana Adler, Hannes Reuter

01.12.2018 | Letter | Ausgabe 1/2018 Open Access

The choice of a postpyloric tube and the patient’s position in our procedure: A response

Bei Hu, Bo Lv, Chunbo Chen

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Influence of pathogen and focus of infection on procalcitonin values in sepsis patients with bacteremia or candidemia

Daniel O. Thomas-Rüddel, Bernhard Poidinger, Matthias Kott, Manfred Weiss, Konrad Reinhart, Frank Bloos, for the MEDUSA study group

01.12.2018 | Letter | Ausgabe 1/2018 Open Access

Ramped position, an uncertain future

Luigi Vetrugno, Daniele Orso, Tiziana Bove

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Metabolic profiles in community-acquired pneumonia: developing assessment tools for disease severity

Pu Ning, Yali Zheng, Qiongzhen Luo, Xiaohui Liu, Yu Kang, Yan Zhang, Rongbao Zhang, Yu Xu, Donghong Yang, Wen Xi, Keqiang Wang, Yusheng Chen, Shuchang An, Zhancheng Gao

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Incidence of hypotension according to the discontinuation order of vasopressors in the management of septic shock: a prospective randomized trial (DOVSS)

Kyeongman Jeon, Jae-Uk Song, Chi Ryang Chung, Jeong Hoon Yang, Gee Young Suh

01.12.2018 | Editorial | Ausgabe 1/2018 Open Access

Acetylcholine receptor antagonists in acute respiratory distress syndrome: much more than muscle relaxants

Diana Jansen, Heder de Vries, Leo M. A. Heunks

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Effect of postoperative goal-directed therapy in cancer patients undergoing high-risk surgery: a randomized clinical trial and meta-analysis

Aline Rejane Muller Gerent, Juliano Pinheiro Almeida, Evgeny Fominskiy, Giovanni Landoni, Gisele Queiroz de Oliveira, Stephanie Itala Rizk, Julia Tizue Fukushima, Claudia Marques Simoes, Ulysses Ribeiro Jr, Clarice Lee Park, Rosana Ely Nakamura, Rafael Alves Franco, Patricia Inês Cândido, Cintia Rosa Tavares, Ligia Camara, Graziela dos Santos Rocha Ferreira, Elisangela Pinto Marinho de Almeida, Roberto Kalil Filho, Filomena Regina Barbosa Gomes Galas, Ludhmila Abrahão Hajjar

01.12.2018 | Letter | Ausgabe 1/2018 Open Access

Effect of intensive glycaemic control on moderate hypoglycaemia and ICU length of stay in severe traumatic brain injury

Rafael A. Núñez-Patiño, Andres Zorrilla-Vaca, Daniel Agustin Godoy

01.12.2018 | Letter | Ausgabe 1/2018 Open Access

Prolonged corticosteroid treatment in acute respiratory distress syndrome: impact on mortality and ventilator-free days

Gianfranco Umberto Meduri, Bram Rochwerg, Djillali Annane, Stephen M. Pastores, on behalf of the Corticosteroid Guideline Task Force of SCCM and ESICM

01.12.2018 | Viewpoint | Ausgabe 1/2018 Open Access

Acute lung injury: how to stabilize a broken lung

Gary F. Nieman, Penny Andrews, Joshua Satalin, Kailyn Wilcox, Michaela Kollisch-Singule, Maria Madden, Hani Aiash, Sarah J. Blair, Louis A. Gatto, Nader M. Habashi

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Temporal biomarker profiles and their association with ICU acquired delirium: a cohort study

Koen S. Simons, Mark van den Boogaard, Eva Hendriksen, Jelle Gerretsen, Johannes G. van der Hoeven, Peter Pickkers, Cornelis P. C. de Jager

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Feasibility of optical coherence tomography angiography to assess changes in retinal microcirculation in ovine haemorrhagic shock

Maged Alnawaiseh, Christian Ertmer, Laura Seidel, Philip Helge Arnemann, Larissa Lahme, Tim-Gerald Kampmeier, Sebastian Willy Rehberg, Peter Heiduschka, Nicole Eter, Michael Hessler

01.12.2018 | Review | Ausgabe 1/2018 Open Access

The role of adrenaline in cardiopulmonary resuscitation

Christopher J. R. Gough, Jerry P. Nolan

01.12.2018 | Review | Ausgabe 1/2018 Open Access

Mechanical CPR: Who? When? How?

Kurtis Poole, Keith Couper, Michael A. Smyth, Joyce Yeung, Gavin D. Perkins

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Long-term use of selective digestive decontamination in an ICU highly endemic for bacterial resistance

Catalina Sánchez-Ramírez, Silvia Hípola-Escalada, Miriam Cabrera-Santana, María Adela Hernández-Viera, Liliana Caipe-Balcázar, Pedro Saavedra, Fernando Artiles-Campelo, Nayra Sangil-Monroy, Carlos Federico Lübbe-Vázquez, Sergio Ruiz-Santana

01.12.2018 | Review | Ausgabe 1/2018 Open Access

Effects of restrictive red blood cell transfusion on the prognoses of adult patients undergoing cardiac surgery: a meta-analysis of randomized controlled trials

Qi-Hong Chen, Hua-Ling Wang, Lei Liu, Jun Shao, Jiangqian Yu, Rui-Qiang Zheng

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Mortality and morbidity in community-acquired sepsis in European pediatric intensive care units: a prospective cohort study from the European Childhood Life-threatening Infectious Disease Study (EUCLIDS)

Navin P. Boeddha, Luregn J. Schlapbach, Gertjan J. Driessen, Jethro A. Herberg, Irene Rivero-Calle, Miriam Cebey-López, Daniela S. Klobassa, Ria Philipsen, Ronald de Groot, David P. Inwald, Simon Nadel, Stéphane Paulus, Eleanor Pinnock, Fatou Secka, Suzanne T. Anderson, Rachel S. Agbeko, Christoph Berger, Colin G. Fink, Enitan D. Carrol, Werner Zenz, Michael Levin, Michiel van der Flier, Federico Martinón-Torres, Jan A. Hazelzet, Marieke Emonts, on behalf of the EUCLIDS consortium

01.12.2018 | Research | Ausgabe 1/2018 Open Access

FIRST-line support for Assistance in Breathing in Children (FIRST-ABC): a multicentre pilot randomised controlled trial of high-flow nasal cannula therapy versus continuous positive airway pressure in paediatric critical care

Padmanabhan Ramnarayan, Paula Lister, Troy Dominguez, Parviz Habibi, Naomi Edmonds, Ruth R. Canter, Jerome Wulff, David A. Harrison, Paul M. Mouncey, Mark J. Peters, on behalf of the United Kingdom Paediatric Intensive Care Society Study Group (PICS-SG)

01.12.2018 | Letter | Ausgabe 1/2018 Open Access

Appraisal of fungal infections during ECMO therapy

Nicolas Mongardon, Ophélie Constant, Fabio Silvio Taccone, Eric Levesque

01.12.2018 | Letter | Ausgabe 1/2018 Open Access

Soluble programmed cell death protein-1 and programmed cell death ligand-1 in sepsis

Debasree Banerjee, Sean Monaghan, Runping Zhao, Thomas Walsh, Amy Palmisciano, Gary S. Phillips, Steven Opal, Mitchell M. Levy

01.12.2018 | Letter | Ausgabe 1/2018 Open Access

Identification of developing multiple organ failure in sepsis patients with low or moderate SOFA scores

Gunnar Elke, Frank Bloos, Darius Cameron Wilson, Patrick Meybohm, the SepNet Critical Care Trials Group

01.12.2018 | Letter | Ausgabe 1/2018 Open Access

Longing for better ultrasound-guided subclavian/axillary venous cannulation

Gentle Sunder Shrestha

01.12.2018 | Letter | Ausgabe 1/2018 Open Access

Are we near to the end of the standard dose of micafungin?

Alexander Agrifoglio, Lucía Cachafeiro, Eva Herrero, Manuel Sánchez, Abelardo García de Lorenzo

01.12.2018 | Review | Ausgabe 1/2018 Open Access

Prognostication after cardiac arrest

Claudio Sandroni, Sonia D’Arrigo, Jerry P. Nolan

01.12.2018 | Letter | Ausgabe 1/2018 Open Access

Dexmedetomidine: the first new kid on the block for preventing cardiac surgery-associated acute kidney injury?

Patrick M. Honore, David De Bels, Thierry Preseau, Herbert D. Spapen

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Albumin mass balance and kinetics in liver transplantation

Mariam Amouzandeh, Greg Nowak, Anna Januszkiewicz, Jan Wernerman, Olav Rooyackers, Åke Norberg

01.12.2018 | Review | Ausgabe 1/2018 Open Access

Antiepileptic drugs in critically ill patients

Salia Farrokh, Pouya Tahsili-Fahadan, Eva K. Ritzl, John J. Lewin III, Marek A. Mirski

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Acute kidney injury and mild therapeutic hypothermia in patients after cardiopulmonary resuscitation - a post hoc analysis of a prospective observational trial

Julia Hasslacher, Fabian Barbieri, Ulrich Harler, Hanno Ulmer, Lui G. Forni, Romuald Bellmann, Michael Joannidis

01.12.2018 | Letter | Ausgabe 1/2018 Open Access

Can nutritional interventions change major clinical outcomes?

Sho Horikita, Masamitsu Sanui, Alan K. Lefor

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Very high intact-protein formula successfully provides protein intake according to nutritional recommendations in overweight critically ill patients: a double-blind randomized trial

Arthur R. H. van Zanten, Laurent Petit, Jan De Waele, Hans Kieft, Janneke de Wilde, Peter van Horssen, Marianne Klebach, Zandrie Hofman

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Immunocompromised patients with acute respiratory distress syndrome: secondary analysis of the LUNG SAFE database

Andrea Cortegiani, Fabiana Madotto, Cesare Gregoretti, Giacomo Bellani, John G. Laffey, Tai Pham, Frank Van Haren, Antonino Giarratano, Massimo Antonelli, Antonio Pesenti, Giacomo Grasselli, LUNG SAFE Investigators and the ESICM Trials Group

01.12.2018 | Editorial | Ausgabe 1/2018 Open Access

Thrombocytopenia in the ICU: disseminated intravascular coagulation and thrombotic microangiopathies—what intensivists need to know

Jean-Louis Vincent, Pedro Castro, Beverley J. Hunt, Achim Jörres, Manuel Praga, Jose Rojas-Suarez, Eizo Watanabe

01.12.2018 | Letter | Ausgabe 1/2018 Open Access

The mechanism of action of the adrenomedullin-binding antibody adrecizumab

Christopher Geven, Peter Pickkers

01.12.2018 | Review | Ausgabe 1/2018 Open Access

Predictors of health-related quality of life after burn injuries: a systematic review

Inge Spronk, Catherine M. Legemate, Jan Dokter, Nancy E. E. van Loey, Margriet E. van Baar, Suzanne Polinder

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Acute kidney injury is associated with a decrease in cortical renal perfusion during septic shock

Anatole Harrois, Nicolas Grillot, Samy Figueiredo, Jacques Duranteau

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Shock subtypes by left ventricular ejection fraction following out-of-hospital cardiac arrest

Ryan J. Anderson, Sayuri P. Jinadasa, Leeyen Hsu, Tiffany Bita Ghafouri, Sanjeev Tyagi, Jisha Joshua, Ariel Mueller, Daniel Talmor, Rebecca E. Sell, Jeremy R. Beitler

01.12.2018 | Viewpoint | Ausgabe 1/2018 Open Access

Position of draining venous cannula in extracorporeal membrane oxygenation for respiratory and respiratory/circulatory support in adult patients

B. Frenckner, M. Broman, M. Broomé

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Early fibrinogen concentrate therapy for major haemorrhage in trauma (E-FIT 1): results from a UK multi-centre, randomised, double blind, placebo-controlled pilot trial

Nicola Curry, Claire Foley, Henna Wong, Ana Mora, Elinor Curnow, Agne Zarankaite, Renate Hodge, Valerie Hopkins, Alison Deary, James Ray, Phil Moss, Matthew J. Reed, Suzanne Kellett, Ross Davenport, Simon Stanworth

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Low b-value diffusion weighted imaging is promising in the diagnosis of brain death and hypoxic-ischemic injury secondary to cardiopulmonary arrest

Miriam E. Peckham, Jeffrey S. Anderson, Ulrich A. Rassner, Lubdha M. Shah, Peter J. Hinckley, Adam de Havenon, Seong-Eun Kim, J. Scott McNally

01.12.2018 | Letter | Ausgabe 1/2018 Open Access

Flexible bronchoscopy-related safety in patients with severe ARDS

A. Guillon, M.-A. Nay, T. Kamel

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Improved empirical antibiotic treatment of sepsis after an educational intervention: the ABISS-Edusepsis study

Ricard Ferrer, María Luisa Martínez, Gemma Gomà, David Suárez, Luis Álvarez-Rocha, María Victoria de la Torre, Gumersindo González, Rafael Zaragoza, Marcio Borges, Jesús Blanco, Eduardo Palencia Herrejón, Antonio Artigas, for the ABISS-Edusepsis Study group

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Postoperative cellular stress in the kidney is associated with an early systemic γδ T-cell immune cell response

Ivan Göcze, Katharina Ehehalt, Florian Zeman, Paloma Riquelme, Karin Pfister, Bernhard M. Graf, Thomas Bein, Edward K. Geissler, Piotr Kasprzak, Hans J. Schlitt, John A. Kellum, James A. Hutchinson, Elke Eggenhofer, Philipp Renner

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Anemia prevalence and incidence and red blood cell transfusion practices in aneurysmal subarachnoid hemorrhage: results of a multicenter cohort study

Shane W. English, Michaël Chassé, Alexis F. Turgeon, François Lauzier, Donald Griesdale, Allan Garland, Dean Fergusson, Ryan Zarychanski, Carl van Walraven, Kaitlyn Montroy, Jennifer Ziegler, Raphael Dupont-Chouinard, Raphaëlle Carignan, Andy Dhaliwal, Ranjeeta Mallick, John Sinclair, Amélie Boutin, Giuseppe Pagliarello, Alan Tinmouth, Lauralyn McIntyre, on behalf of the Canadian Critical Care Trials Group

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Gastric versus postpyloric enteral nutrition in elderly patients (age ≥ 75 years) on mechanical ventilation: a single-center randomized trial

Youfeng Zhu, Haiyan Yin, Rui Zhang, Xiaoling Ye, Jianrui Wei

01.12.2018 | Editorial | Ausgabe 1/2018 Open Access

Use of ECMO in ARDS: does the EOLIA trial really help?

Luciano Gattinoni, Francesco Vasques, Michael Quintel

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Emergency Department disposition decisions and associated mortality and costs in ICU patients with suspected infection

Shannon M. Fernando, Bram Rochwerg, Peter M. Reardon, Kednapa Thavorn, Andrew J. E. Seely, Jeffrey J. Perry, Douglas P. Barnaby, Peter Tanuseputro, Kwadwo Kyeremanteng

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Early application of continuous high-volume haemofiltration can reduce sepsis and improve the prognosis of patients with severe burns

Bo You, Yu Long Zhang, Gao Xing Luo, Yong Ming Dang, Bei Jiang, Guang Tao Huang, Xin Zhu Liu, Zi Chen Yang, Yu Chen, Jing Chen, Zhi Qiang Yuan, Su Peng Yin, Yi Zhi Peng

01.12.2018 | Review | Ausgabe 1/2018 Open Access

Definitions and pathophysiology of vasoplegic shock

Simon Lambden, Ben C. Creagh-Brown, Julie Hunt, Charlotte Summers, Lui G. Forni

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Clinical characteristics and prognosis of bacteraemia during postoperative intra-abdominal infections

Adel Alqarni, Elie Kantor, Nathalie Grall, Sebastien Tanaka, Nathalie Zappella, Mathieu Godement, Lara Ribeiro-Parenti, Alexy Tran-Dinh, Philippe Montravers

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Plasma myeloperoxidase-conjugated DNA level predicts outcomes and organ dysfunction in patients with septic shock

Yuki Maruchi, Masanobu Tsuda, Hisatake Mori, Nobuyoshi Takenaka, Takayoshi Gocho, Muhammad A. Huq, Naoshi Takeyama

01.12.2018 | Letter | Ausgabe 1/2018 Open Access

The kinetic glomerular filtration rate is not interchangeable with measured creatinine clearance for prediction of piperacillin underexposure in critically ill patients with augmented renal clearance

Cédric Carrié, Sébastien Rubin, Pierre Sioniac, Dominique Breilh, Matthieu Biais

01.12.2018 | Letter | Ausgabe 1/2018 Open Access

Specific dynamic of serum procalcitonin in critically ill patients affected by Gram-negative bacilli septic thrombophlebitis

Martina Spaziante, Giancarlo Ceccarelli, Samir Al Moghazi, Francesco Alessandri, Mario Venditti

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Effect of decompressive laparotomy on organ function in patients with abdominal compartment syndrome: a systematic review and meta-analysis

Lana Van Damme, Jan J. De Waele

01.12.2018 | Research | Ausgabe 1/2018 Open Access

High-flow nasal cannula oxygen therapy decreases postextubation neuroventilatory drive and work of breathing in patients with chronic obstructive pulmonary disease

Rosa Di mussi, Savino Spadaro, Tania Stripoli, Carlo Alberto Volta, Paolo Trerotoli, Paola Pierucci, Francesco Staffieri, Francesco Bruno, Luigi Camporota, Salvatore Grasso

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Erythrocyte P2X1 receptor expression is correlated with change in haematocrit in patients admitted to the ICU with blood pathogen-positive sepsis

Steen K. Fagerberg, Parth Patel, Lars W. Andersen, Xiaowen Lui, Michael W. Donnino, Helle A. Praetorius

01.12.2018 | Review | Ausgabe 1/2018 Open Access

Improving glycemic control in critically ill patients: personalized care to mimic the endocrine pancreas

J. Geoffrey Chase, Thomas Desaive, Julien Bohe, Miriam Cnop, Christophe De Block, Jan Gunst, Roman Hovorka, Pierre Kalfon, James Krinsley, Eric Renard, Jean-Charles Preiser

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Left ventricular systolic function evaluated by strain echocardiography and relationship with mortality in patients with severe sepsis or septic shock: a systematic review and meta-analysis

F. Sanfilippo, C. Corredor, N. Fletcher, L. Tritapepe, F. L. Lorini, A. Arcadipane, A. Vieillard-Baron, M. Cecconi

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Value and mechanisms of EEG reactivity in the prognosis of patients with impaired consciousness: a systematic review

Eric Azabou, Vincent Navarro, Nathalie Kubis, Martine Gavaret, Nicholas Heming, Alain Cariou, Djillali Annane, Fréderic Lofaso, Lionel Naccache, Tarek Sharshar

01.12.2018 | Review | Ausgabe 1/2018 Open Access

Platelet storage duration and its clinical and transfusion outcomes: a systematic review

Cécile Aubron, Andrew W. J. Flint, Yves Ozier, Zoe McQuilten

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Validation of carbon dioxide production (VCO2) as a tool to calculate resting energy expenditure (REE) in mechanically ventilated critically ill patients: a retrospective observational study

I. Kagan, O. Zusman, I. Bendavid, M. Theilla, J. Cohen, P. Singer

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Corticosteroid use and intensive care unit-acquired weakness: a systematic review and meta-analysis

Tao Yang, Zhiqiang Li, Li Jiang, Xiuming Xi

01.12.2018 | Research | Ausgabe 1/2018 Open Access

A worldwide multicentre evaluation of the influence of deterioration or improvement of acute kidney injury on clinical outcome in critically ill patients with and without sepsis at ICU admission: results from The Intensive Care Over Nations audit

Esther Peters, Massimo Antonelli, Xavier Wittebole, Rahul Nanchal, Bruno François, Yasser Sakr, Jean-Louis Vincent, Peter Pickkers

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Effects of hyperoxia on vascular tone in animal models: systematic review and meta-analysis

Bob Smit, Yvo M. Smulders, Etto C. Eringa, Heleen M. Oudemans - van Straaten, Armand R. J. Girbes, Kimberley E. Wever, Carlijn R. Hooijmans, Angelique M. E. Spoelstra - de Man

01.12.2018 | Review | Ausgabe 1/2018 Open Access

Airway and ventilation management during cardiopulmonary resuscitation and after successful resuscitation

Christopher Newell, Scott Grier, Jasmeet Soar

01.12.2018 | Review | Ausgabe 1/2018 Open Access

Effect of procalcitonin-guided antibiotic treatment on clinical outcomes in intensive care unit patients with infection and sepsis patients: a patient-level meta-analysis of randomized trials

Yannick Wirz, Marc A. Meier, Lila Bouadma, Charles E. Luyt, Michel Wolff, Jean Chastre, Florence Tubach, Stefan Schroeder, Vandack Nobre, Djillali Annane, Konrad Reinhart, Pierre Damas, Maarten Nijsten, Arezoo Shajiei, Dylan W. deLange, Rodrigo O. Deliberato, Carolina F. Oliveira, Yahya Shehabi, Jos A. H. van Oers, Albertus Beishuizen, Armand R. J. Girbes, Evelien de Jong, Beat Mueller, Philipp Schuetz

01.12.2018 | Letter | Ausgabe 1/2018 Open Access

Bundle of care taking into account time to improve long-term outcome after cardiac arrest

R. Jouffroy, B. Vivien

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Intravenous ivabradine versus placebo in patients with low cardiac output syndrome treated by dobutamine after elective coronary artery bypass surgery: a phase 2 exploratory randomized controlled trial

Lee S. Nguyen, Pierre Squara, Julien Amour, Daniel Carbognani, Kamel Bouabdallah, Stéphane Thierry, Caroline Apert-Verneuil, Aurélie Moyne, Bernard Cholley

01.12.2018 | Letter | Ausgabe 1/2018 Open Access

Hemodynamic management of critically ill burn patients: an international survey

Sabri Soussi, Mette M. Berger, Kirsten Colpaert, Martin W. Dünser, Anne Berit Guttormsen, Nicole P. Juffermans, Paul Knape, Guniz Koksal, Athina Lavrentieva, Thomas Leclerc, José A. Lorente, Ignacio Martin-Loeches, Philipp Metnitz, Olivier Pantet, Paolo Pelosi, Anne-Françoise Rousseau, Folke Sjöberg, Matthieu Legrand, for the ESICM Burn ICU working group

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Epidemiology and patterns of tracheostomy practice in patients with acute respiratory distress syndrome in ICUs across 50 countries

Toshikazu Abe, Fabiana Madotto, Tài Pham, Isao Nagata, Masatoshi Uchida, Nanako Tamiya, Kiyoyasu Kurahashi, Giacomo Bellani, John G. Laffey, for the LUNG-SAFE Investigators and the ESICM Trials Group

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Carbon dioxide dynamics in relation to neurological outcome in resuscitated out-of-hospital cardiac arrest patients: an exploratory Target Temperature Management Trial substudy

Florian Ebner, Matt B. A. Harmon, Anders Aneman, Tobias Cronberg, Hans Friberg, Christian Hassager, Nicole Juffermans, Jesper Kjærgaard, Michael Kuiper, Niklas Mattsson, Paolo Pelosi, Susann Ullén, Johan Undén, Matt P. Wise, Niklas Nielsen

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Predicting acute kidney injury using urinary liver-type fatty-acid binding protein and serum N-terminal pro-B-type natriuretic peptide levels in patients treated at medical cardiac intensive care units

Hiroyuki Naruse, Junnichi Ishii, Hiroshi Takahashi, Fumihiko Kitagawa, Hideto Nishimura, Hideki Kawai, Takashi Muramatsu, Masahide Harada, Akira Yamada, Sadako Motoyama, Shigeru Matsui, Mutsuharu Hayashi, Masayoshi Sarai, Eiichi Watanabe, Hideo Izawa, Yukio Ozaki

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Feasibility of biventricular 3D transthoracic echocardiography in the critically ill and comparison with conventional parameters

Sam Orde, Michel Slama, Nicola Stanley, Stephen Huang, Anthony Mclean

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Predictors of insufficient peak amikacin concentration in critically ill patients on extracorporeal membrane oxygenation

Cyril Touchard, Alexandra Aubry, Philippine Eloy, Nicolas Bréchot, Guillaume Lebreton, Guillaume Franchineau, Sebastien Besset, Guillaume Hékimian, Ania Nieszkowska, Pascal Leprince, Charles-Edouard Luyt, Alain Combes, Matthieu Schmidt

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Investigation of microcirculation in patients with venoarterial extracorporeal membrane oxygenation life support

Yu-Chang Yeh, Chen-Tse Lee, Chih-Hsien Wang, Yu-Kang Tu, Chien-Heng Lai, Yin-Chin Wang, Anne Chao, Chi-Hsiang Huang, Ya-Jung Cheng, Yih-Sharng Chen, on behalf of the NTUH Center of Microcirculation Medical Research (NCMMR)

01.12.2018 | Letter | Ausgabe 1/2018 Open Access

Predicting the requirement for renal replacement therapy in intensive care patients with sepsis

Axel Nierhaus, Frank Bloos, Darius Cameron Wilson, Gunnar Elke, Patrick Meybohm, the SepNet Critical Care Trials Group

01.12.2018 | Letter | Ausgabe 1/2018 Open Access

Loop diuretic use in patients with AKI: different severity, different response

Yanfei Shen, Muying Wu

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Chest radiography versus lung ultrasound for identification of acute respiratory distress syndrome: a retrospective observational study

Kay Choong See, Venetia Ong, Yi Lin Tan, Juliet Sahagun, Juvel Taculod

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Value of variation index of inferior vena cava diameter in predicting fluid responsiveness in patients with circulatory shock receiving mechanical ventilation: a systematic review and meta-analysis

Haijun Huang, Qinkang Shen, Yafen Liu, Hua Xu, Yixin Fang

01.12.2018 | Letter | Ausgabe 1/2018 Open Access

Efficacy of polymyxin B hemoperfusion in and beyond septic shock: is an “endotoxin severity score” needed?

Patrick M. Honore, David De Bels, Thierry Preseau, Sebastien Redant, Herbert D. Spapen

01.12.2018 | Letter | Ausgabe 1/2018 Open Access

Could ultrasound-guided internal jugular vein catheter insertion replace the use of chest X-ray?

William F. Amaya-Zuñiga, Fernando Raffán-Sanabria

01.12.2018 | Letter | Ausgabe 1/2018 Open Access

Adjuvant vitamin C in cardiac arrest patients undergoing renal replacement therapy: an appeal for a higher high-dose

Patrick M. Honore, David De Bels, Thierry Preseau, Sebastien Redant, Rachid Attou, Herbert D. Spapen

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Reassessing access to intensive care using an estimate of the population incidence of critical illness

Allan Garland, Kendiss Olafson, Clare D. Ramsey, Marina Yogendranc, Randall Fransoo

01.12.2018 | Editorial | Ausgabe 1/2018 Open Access

Histidine-rich glycoprotein as an excellent biomarker for sepsis and beyond

Masahiro Nishibori, Hidenori Wake, Hiroshi Morimatsu

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Functional outcomes in adults with tuberculous meningitis admitted to the ICU: a multicenter cohort study

Marie Cantier, Adeline Morisot, Emmanuel Guérot, Bruno Megarbane, Keyvan Razazi, Damien Contou, Eric Mariotte, Emmanuel Canet, Etienne De Montmollin, Vincent Dubée, Eric Boulet, Stéphane Gaudry, Guillaume Voiriot, Julien Mayaux, Frédéric Pène, Mathilde Neuville, Bruno Mourvillier, Stéphane Ruckly, Lila Bouadma, Michel Wolff, Jean-François Timsit, Romain Sonneville, ENCEPHALITICA study group

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Women in Intensive Care study: a preliminary assessment of international data on female representation in the ICU physician workforce, leadership and academic positions

Bala Venkatesh, Sangeeta Mehta, Derek C. Angus, Simon Finfer, Flavia R. Machado, John Marshall, Imogen Mitchell, Sandra Peake, Janice L. Zimmerman

01.12.2018 | Review | Ausgabe 1/2018 Open Access

Ethical aspects of sudden cardiac arrest research using observational data: a narrative review

Marieke A. R. Bak, Marieke T. Blom, Hanno L. Tan, Dick L. Willems

01.12.2018 | Letter | Ausgabe 1/2018 Open Access

Massive increase in monocyte HLA-DR expression can be used to discriminate between septic shock and hemophagocytic lymphohistiocytosis-induced shock

Solenn Remy, Morgane Gossez, Alexandre Belot, Jack Hayman, Aurelie Portefaix, Fabienne Venet, Etienne Javouhey, Guillaume Monneret

01.12.2018 | Editorial | Ausgabe 1/2018 Open Access

We should avoid the term “fluid overload”

Jean-Louis Vincent, Michael R. Pinsky

01.12.2018 | Viewpoint | Ausgabe 1/2018 Open Access

Refractory septic shock: our pragmatic approach

Prashanth Nandhabalan, Nicholas Ioannou, Christopher Meadows, Duncan Wyncoll

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Symmetrical (SDMA) and asymmetrical dimethylarginine (ADMA) in sepsis: high plasma levels as combined risk markers for sepsis survival

Martin Sebastian Winkler, Axel Nierhaus, Gilbert Rösler, Susanne Lezius, Olaf Harlandt, Edzard Schwedhelm, Rainer H. Böger, Stefan Kluge

01.12.2018 | Editorial | Ausgabe 1/2018 Open Access

When to initiate ECMO with low likelihood of success

Graeme MacLaren

01.12.2018 | Letter | Ausgabe 1/2018 Open Access

Hyperoxia effects on intensive care unit mortality: a retrospective pragmatic cohort study

Mathilde Ruggiu, Nadia Aissaoui, Julien Nael, Caroline Haw-Berlemont, Bertrand Herrmann, Jean-Loup Augy, Sofia Ortuno, Damien Vimpère, Jean-Luc Diehl, Clotilde Bailleul, Emmanuel Guerot

01.12.2018 | Letter | Ausgabe 1/2018 Open Access

Studies should fully report on variables that determine the dynamics and the temperature gradients during hypothermia

Horia-Nicolai Teodorescu

01.12.2018 | Letter | Ausgabe 1/2018 Open Access

Gender differences in the use of atypical antipsychotic medications for ICU delirium

Kunal Karamchandani, Robert S. Schoaps, Jillian Printz, Jeffrey M. Kowaleski, Zyad J. Carr

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Regional expiratory time constants in severe respiratory failure estimated by electrical impedance tomography: a feasibility study

Christian Karagiannidis, Andreas D. Waldmann, Péter L. Róka, Tina Schreiber, Stephan Strassmann, Wolfram Windisch, Stephan H. Böhm

01.12.2018 | Letter | Ausgabe 1/2018 Open Access

Extracorporeal membrane oxygenation offers long-term survival in childhood leukemia and acute respiratory failure

Gerard Cortina, Nikolaus Neu, Gabriele Kropshofer, Bernhard Meister, Uwe Klingkowski, Roman Crazzolara

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Net ultrafiltration intensity and mortality in critically ill patients with fluid overload

Raghavan Murugan, Vikram Balakumar, Samantha J. Kerti, Priyanka Priyanka, Chung-Chou H. Chang, Gilles Clermont, Rinaldo Bellomo, Paul M. Palevsky, John A. Kellum

01.12.2018 | Editorial | Ausgabe 1/2018 Open Access

The path to great pediatric septic shock outcomes

Stefanie G. Ames, Christopher M. Horvat, Arno Zaritsky, Joseph A. Carcillo

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Costs, outcome and cost-effectiveness of neurocritical care: a multi-center observational study

R. Raj, S. Bendel, M. Reinikainen, S. Hoppu, R. Laitio, T. Ala-Kokko, S. Curtze, M. B. Skrifvars

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Categorization of post-cardiac arrest patients according to the pattern of amplitude-integrated electroencephalography after return of spontaneous circulation

Kazuhiro Sugiyama, Kazuki Miyazaki, Takuto Ishida, Takahiro Tanabe, Yuichi Hamabe

01.12.2018 | Research | Ausgabe 1/2018 Open Access

The association of clinical frailty with outcomes of patients reviewed by rapid response teams: an international prospective observational cohort study

Ralph K. L. So, Jonathan Bannard-Smith, Chris P. Subbe, Daryl A. Jones, Joost van Rosmalen, Geoffrey K. Lighthall, the METHOD study investigators

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Driving-pressure-independent protective effects of open lung approach against experimental acute respiratory distress syndrome

Kentaro Tojo, Tasuku Yoshida, Takuya Yazawa, Takahisa Goto

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Enteral nutrition feeding in Chinese intensive care units: a cross-sectional study involving 116 hospitals

Juan Xing, Zhongheng Zhang, Lu Ke, Jing Zhou, Bingyu Qin, Hongkai Liang, Xiaomei Chen, Wenming Liu, Zhongmin Liu, Yuhang Ai, Difeng Wang, Qiuhui Wang, Qingshan Zhou, Fusen Zhang, Kejian Qian, Dongpo Jiang, Bin Zang, Yimin Li, Xiaobo Huang, Yan Qu, Yinguang Xie, Donglin Xu, Zhiqiang Zou, Xiangde Zheng, Jianbo Liu, Feng Guo, Yafeng Liang, Qiang Sun, Hongmei Gao, Yang Liu, Ping Chang, Aibin Ceng, Rongli Yang, Gaiqi Yao, Yun Sun, Xiaorong Wang, Yi Zhang, Yichao Wen, Jian Yu, Rongqing Sun, Zhiwei Li, Shiying Yuan, Yunlin Song, Peiyang Gao, Haiyan Liu, Zhaohui Zhang, Yunfu Wu, Biao Ma, Qiang Guo, Feng Shan, Mingshi Yang, Hailing Li, Yuanfei Li, Weihua Lu, Lei Wang, Chuangyun Qian, Zhiyong Wang, Jiandong Lin, Rumin Zhang, Peng Wan, Zhiyong Peng, Yuqiang Gong, Linxi Huang, Guobao Wu, Jie Sun, Yijun Deng, Dongwu Shi, Lixin Zhou, Fachun Zhou, Qindong Shi, Xiaodong Guo, Xueyan Liu, Weidong Wu, Xiangzhong Meng, Liandi Li, Weiwei Chen, Shusheng Li, Xianyao Wan, Zhixin Chao, An Zhang, Liming Gu, Wei Chen, Jinglan Wu, Lihua Zhou, Zhenhuan Zhang, Yibing Weng, Yongshun Feng, Chunli Yang, Yongjian Feng, Sumin Zhao, Fei Tong, Dong Hao, Hui Han, Baocai Fu, Chuanyong Gong, Zhiping Li, Kunlin Hu, Qiuye Kou, Han Zhang, Jie Liu, Chuming Fan, Xin Zhou, Xiumei Chen, Junli Sun, Xuejun Zhou, Bin Song, Cheng Sun, Liyun Zhao, Xinglu Dong, Linlin Zhang, Dafei Tong, Zhiguo Pan, Chuangjie Cai, Donghao Wang, Yingjun Dong, Yuanqi Gong, Zhisong Wu, Xinke Meng, Ping Wang, Weiqin Li

01.12.2018 | Letter | Ausgabe 1/2018 Open Access

Is protein intake saturated at doses recommended by the feeding guidelines for critically ill patients?

Jan Gunst, Michael P. Casaer

01.12.2018 | Viewpoint | Ausgabe 1/2018 Open Access

The role of bile acids in nutritional support

Gustav van Niekerk, Tanja Davis, Willem de Villiers, Anna-Mart Engelbrecht

01.12.2018 | Review | Ausgabe 1/2018 Open Access

The global burden of sepsis: barriers and potential solutions

Kristina E. Rudd, Niranjan Kissoon, Direk Limmathurotsakul, Sotharith Bory, Birungi Mutahunga, Christopher W. Seymour, Derek C. Angus, T. Eoin West

01.12.2018 | Review | Ausgabe 1/2018 Open Access

Pharmacokinetics–pharmacodynamics issues relevant for the clinical use of beta-lactam antibiotics in critically ill patients

Rui Pedro Veiga, José-Artur Paiva

01.12.2018 | Letter | Ausgabe 1/2018 Open Access

The relationship between the decrease in haemoglobin concentration and the volume of fluids administered during resuscitation from septic shock may not be so “weak”

Azriel Perel

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Endotracheal tube-mounted camera-assisted intubation versus conventional intubation in intensive care: a prospective, randomised trial (VivaITN)

Jörn Grensemann, Lars Eichler, Nuowei Wang, Dominik Jarczak, Marcel Simon, Stefan Kluge

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Risk factors and outcomes for airway failure versus non-airway failure in the intensive care unit: a multicenter observational study of 1514 extubation procedures

Samir Jaber, Hervé Quintard, Raphael Cinotti, Karim Asehnoune, Jean-Michel Arnal, Christophe Guitton, Catherine Paugam-Burtz, Paer Abback, Armand Mekontso Dessap, Karim Lakhal, Sigismond Lasocki, Gaetan Plantefeve, Bernard Claud, Julien Pottecher, Philippe Corne, Carole Ichai, Zied Hajjej, Nicolas Molinari, Gerald Chanques, Laurent Papazian, Elie Azoulay, Audrey De Jong

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Septic shock-3 vs 2: an analysis of the ALBIOS study

Francesco Vasques, Eleonora Duscio, Federica Romitti, Iacopo Pasticci, Pietro Caironi, Jennifer Meessen, Roberto Latini, Massimo Cressoni, Luigi Camporota, Antonio Pesenti, Roberto Fumagalli, Michael Quintel, Luciano Gattinoni

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Estimation of the diaphragm neuromuscular efficiency index in mechanically ventilated critically ill patients

Diana Jansen, Annemijn H. Jonkman, Lisanne Roesthuis, Suvarna Gadgil, Johannes G. van der Hoeven, Gert-Jan J. Scheffer, Armand Girbes, Jonne Doorduin, Christer S. Sinderby, Leo M. A. Heunks

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Synbiotics modulate gut microbiota and reduce enteritis and ventilator-associated pneumonia in patients with sepsis: a randomized controlled trial

Kentaro Shimizu, Tomoki Yamada, Hiroshi Ogura, Tomoyoshi Mohri, Takeyuki Kiguchi, Satoshi Fujimi, Takashi Asahara, Tomomi Yamada, Masahiro Ojima, Mitsunori Ikeda, Takeshi Shimazu

01.12.2018 | Research | Ausgabe 1/2018 Open Access

In vivo quantification of rolling and adhered leukocytes in human sepsis

Bjorn K. Fabian-Jessing, Michael J. Massey, Michael R. Filbin, Peter C. Hou, Henry E. Wang, Hans Kirkegaard, Donald M. Yealy, William C. Aird, John A. Kellum, Derek C. Angus, Nathan I. Shapiro, on behalf of the ProCESS Investigators

01.12.2018 | Research | Ausgabe 1/2018 Open Access

A complete and multifaceted overview of antibiotic use and infection diagnosis in the intensive care unit: results from a prospective four-year registration

Liesbet De Bus, Bram Gadeyne, Johan Steen, Jerina Boelens, Geert Claeys, Dominique Benoit, Jan De Waele, Johan Decruyenaere, Pieter Depuydt

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Refractory out-of-hospital cardiac arrest with ongoing cardiopulmonary resuscitation at hospital arrival – survival and neurological outcome without extracorporeal cardiopulmonary resuscitation

Emilie Gregers, Jesper Kjærgaard, Freddy Lippert, Jakob H. Thomsen, Lars Køber, Michael Wanscher, Christian Hassager, Helle Søholm

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Carriage of antibiotic-resistant Gram-negative bacteria after discontinuation of selective decontamination of the digestive tract (SDD) or selective oropharyngeal decontamination (SOD)

E. de Jonge, R. B. P. de Wilde, N. P. Juffermans, E. A. N. Oostdijk, A. T. Bernards, E. H. R. van Essen, E. J. Kuijper, C. E. Visser, J. Kesecioglu, M. J. M. Bonten

01.12.2018 | Research | Ausgabe 1/2018 Open Access

The glucocorticoid receptor and cortisol levels in pediatric septic shock

Matthew N. Alder, Amy M. Opoka, Hector R. Wong

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Dorsal recruitment with flow-controlled expiration (FLEX): an experimental study in mechanically ventilated lung-healthy and lung-injured pigs

Silke Borgmann, Johannes Schmidt, Ulrich Goebel, Joerg Haberstroh, Josef Guttmann, Stefan Schumann

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Comparison of outcomes between vertical and transverse skin incisions in percutaneous tracheostomy for critically ill patients: a retrospective cohort study

Sung Yoon Lim, Won Gun Kwack, Youlim Kim, Yeon Joo Lee, Jong Sun Park, Ho Il Yoon, Jae Ho Lee, Choon-Taek Lee, Young-Jae Cho

01.12.2018 | Letter | Ausgabe 1/2018 Open Access

Can a simple chemical help to both prevent and treat sepsis

Anitra C. Carr

01.12.2018 | Research | Ausgabe 1/2018 Open Access

The interleukin-27 -964A>G polymorphism enhances sepsis-induced inflammatory responses and confers susceptibility to the development of sepsis

Junbing He, Quanfu Zhang, Wenying Zhang, Feng Chen, Tian Zhao, Yao Lin, Jia Li, Yansong Liu, Yuchun Liu, Yiming Shao

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Focal ischemic stroke leads to lung injury and reduces alveolar macrophage phagocytic capability in rats

Cynthia S. Samary, Alane B. Ramos, Lígia A. Maia, Nazareth N. Rocha, Cíntia L. Santos, Raquel F. Magalhães, Amanda L. Clevelario, Pedro M. Pimentel-Coelho, Rosália Mendez-Otero, Fernanda F. Cruz, Vera L. Capelozzi, Tatiana P. T. Ferreira, Thea Koch, Marcelo Gama de Abreu, Claudia C. dos Santos, Paolo Pelosi, Pedro L. Silva, Patricia R. M. Rocco

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Noise in the intensive care unit and its influence on sleep quality: a multicenter observational study in Dutch intensive care units

Koen S. Simons, Eva Verweij, Paul M. C. Lemmens, Sam Jelfs, Munhum Park, Peter E. Spronk, Johannes P. C. Sonneveld, Hilde-Marieken Feijen, Marijke S. van der Steen, Armin G. Kohlrausch, Mark van den Boogaard, Cornelis P. C. de Jager

01.12.2018 | Research | Ausgabe 1/2018 Open Access

An early increase in endothelial protein C receptor is associated with excess mortality in pneumococcal pneumonia with septic shock in the ICU

Agnès Chapelet, Yohann Foucher, Nathalie Gérard, Christophe Rousseau, Olivier Zambon, Cédric Bretonnière, Jean-Paul Mira, Béatrice Charreau, Christophe Guitton

01.12.2018 | Letter | Ausgabe 1/2018 Open Access

Comparison between procalcitonin and C-reactive protein to predict blood culture results in ICU patients

Matteo Bassetti, Alessandro Russo, Elda Righi, Elisabetta Dolso, Maria Merelli, Nicola Cannarsa, Federica D’Aurizio, Assunta Sartor, Francesco Curcio

01.12.2018 | Letter | Ausgabe 1/2018 Open Access

Bougie-in-channel intubation technique

Kay Choong See, Melanie Estaras, Rolando Capistrano, Sui Hua Wong, Juliet Sahagun, Juvel Taculod

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Validation of CLIF-C ACLF score to define a threshold for futility of intensive care support for patients with acute-on-chronic liver failure

Cornelius Engelmann, Karen Louise Thomsen, Nekisa Zakeri, Mohammed Sheikh, Banwari Agarwal, Rajiv Jalan, Rajeshwar P. Mookerjee

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Association between diuretics and successful discontinuation of continuous renal replacement therapy in critically ill patients with acute kidney injury

Junseok Jeon, Do Hee Kim, Song In Baeg, Eun Jeong Lee, Chi Ryang Chung, Kyeongman Jeon, Jung Eun Lee, Wooseong Huh, Gee Young Suh, Yoon-Goo Kim, Dae Joong Kim, Ha Young Oh, Hye Ryoun Jang

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Subclinical acute kidney injury is associated with adverse outcomes in critically ill neonates and children

Fang Fang, Xiaohan Hu, Xiaomei Dai, Sanfeng Wang, Zhenjiang Bai, Jiao Chen, Jian Pan, Xiaozhong Li, Jian Wang, Yanhong Li

01.12.2018 | Review | Ausgabe 1/2018 Open Access

The meaning of blood pressure

S. Magder

01.12.2018 | Commentary | Ausgabe 1/2018 Open Access

Evidence is stronger than you think: a meta-analysis of vitamin C use in patients with sepsis

Jing Li

01.12.2018 | Letter | Ausgabe 1/2018 Open Access

Epidemiology of subsequent bloodstream infections in the ICU

Niccolò Buetti, Elia Lo Priore, Rami Sommerstein, Andrew Atkinson, Andreas Kronenberg, Jonas Marschall, the Swiss Centre for Antibiotic resistance (ANRESIS)

01.12.2018 | Viewpoint | Ausgabe 1/2018 Open Access

New perspectives on substituted relational autonomy for shared decision-making in critical care

Nicola Grignoli, Valentina Di Bernardo, Roberto Malacrida

01.12.2018 | Viewpoint | Ausgabe 1/2018 Open Access

High protein intake during the early phase of critical illness: yes or no?

Jean-Charles Preiser

01.12.2018 | Review | Ausgabe 1/2018 Open Access

Extracorporeal techniques for the treatment of critically ill patients with sepsis beyond conventional blood purification therapy: the promises and the pitfalls

Ghada Ankawi, Mauro Neri, Jingxiao Zhang, Andrea Breglia, Zaccaria Ricci, Claudio Ronco

01.12.2018 | Review | Ausgabe 1/2018 Open Access

Electrical impedance tomography in acute respiratory distress syndrome

M Consuelo Bachmann, Caio Morais, Guillermo Bugedo, Alejandro Bruhn, Arturo Morales, João B Borges, Eduardo Costa, Jaime Retamal

01.12.2018 | Editorial | Ausgabe 1/2018 Open Access

Volutrauma and atelectrauma: which is worse?

Luciano Gattinoni, Michael Quintel, John J. Marini

01.12.2018 | Letter | Ausgabe 1/2018 Open Access

Differences in attitudes towards end-of-life care among intensivists, oncologists and prosecutors in Brazil: a nationwide survey

João Gabriel Rosa Ramos, Roberto D’Oliveira Vieira, Fernanda Correia Tourinho, Andre Ismael, Diaulas Costa Ribeiro, Humberto Jacques de Medeiro, Daniel Neves Forte

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Factors associated with recurrence and mortality in central line-associated bloodstream infections: a retrospective cohort study

Luis E Huerta, George E Nelson, Thomas G Stewart, Todd W Rice

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Impact of a remifentanil supply shortage on mechanical ventilation in a tertiary care hospital: a retrospective comparison

Daniel A Klaus, Albert M de Bettignies, Rudolf Seemann, Claus G Krenn, Georg A Roth

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Identifying associations between diabetes and acute respiratory distress syndrome in patients with acute hypoxemic respiratory failure: an analysis of the LUNG SAFE database

Andrew J. Boyle, Fabiana Madotto, John G. Laffey, Giacomo Bellani, Tài Pham, Antonio Pesenti, B. Taylor Thompson, Cecilia M. O’Kane, Adam M. Deane, Daniel F. McAuley, on behalf of the LUNG SAFE Investigators, the ESICM Trials Group

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Angiotensin-(1–7) attenuates organ injury and mortality in rats with polymicrobial sepsis

Hsin-Jung Tsai, Mei-Hui Liao, Chih-Chin Shih, Shuk-Man Ka, Cheng-Ming Tsao, Chin-Chen Wu

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Permissive fluid volume in adult patients undergoing extracorporeal membrane oxygenation treatment

Hyoungnae Kim, Jin Hyuk Paek, Joo Han Song, Hajeong Lee, Jong Hyun Jhee, Seohyun Park, Hae-Ryong Yun, Youn Kyung Kee, Seung Hyeok Han, Tae-Hyun Yoo, Shin-Wook Kang, Sejoong Kim, Jung Tak Park

01.12.2018 | Review | Ausgabe 1/2018 Open Access

Bacterial contamination of platelets for transfusion: strategies for prevention

Jerrold H. Levy, Matthew D. Neal, Jay H. Herman

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Can probiotics be an alternative to chlorhexidine for oral care in the mechanically ventilated patient? A multicentre, prospective, randomised controlled open trial

Bengt Klarin, Anne Adolfsson, Anders Torstensson, Anders Larsson

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Determinants of sepsis knowledge: a representative survey of the elderly population in Germany

Sarah Eitze, Carolin Fleischmann-Struzek, Cornelia Betsch, Konrad Reinhart, the vaccination60+ study group

01.12.2018 | Commentary | Ausgabe 1/2018 Open Access

Angiotensin converting enzyme defects in shock: implications for future therapy

Lakhmir S. Chawla, Steve Chen, Rinaldo Bellomo, George F. Tidmarsh

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Carbonic anhydrase inhibitors in patients with respiratory failure and metabolic alkalosis: a systematic review and meta-analysis of randomized controlled trials

Bassem Y Tanios, Maryam O Omran, Carlos Noujeim, Tamara Lotfi, Samir S Mallat, Pierre K Bou-Khalil, Elie A Akl, Houssam S Itani

01.12.2018 | Review | Ausgabe 1/2018 Open Access

Vitamin D deficiency and supplementation in critical illness—the known knowns and known unknowns

Priya Nair, Balasubramaniam Venkatesh, Jacqueline R Center

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Hyperchloremia and postoperative acute kidney injury: a retrospective analysis of data from the surgical intensive care unit

Tak Kyu Oh, In-Ae Song, Se Joong Kim, Sung Yoon Lim, Sang-Hwan Do, Jung-Won Hwang, Jinhee Kim, Young-Tae Jeon

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Development and internal validation of the multivariable CIPHER (Collaborative Integrated Pregnancy High-dependency Estimate of Risk) clinical risk prediction model

Beth A. Payne, Helen Ryan, Jeffrey Bone, Laura A. Magee, Alice B. Aarvold, J. Mark Ansermino, Zulfiqar A. Bhutta, Mary Bowen, J. Guilherme Cecatti, Cynthia Chazotte, Tim Crozier, Anne-Cornélie J. M. de Pont, Oktay Demirkiran, Tao Duan, Marlot Kallen, Wessel Ganzevoort, Michael Geary, Dena Goffman, Jennifer A. Hutcheon, K. S. Joseph, Stephen E. Lapinsky, Isam Lataifeh, Jing Li, Sarka Liskonova, Emily M. Hamel, Fionnuala M. McAuliffe, Colm O’Herlihy, Ben W. J. Mol, P. Gareth R. Seaward, Ramzy Tadros, Turkan Togal, Rahat Qureshi, U. Vivian Ukah, Daniela Vasquez, Euan Wallace, Paul Yong, Vivian Zhou, Keith R. Walley, Peter von Dadelszen, the CIPHER Group

01.12.2018 | Research | Ausgabe 1/2018 Open Access

The effect of polymyxin B hemoperfusion on modulation of human leukocyte antigen DR in severe sepsis patients

Nattachai Srisawat, Somkanya Tungsanga, Nuttha Lumlertgul, Chalermchai Komaenthammasophon, Sadudee Peerapornratana, Nicha Thamrongsat, Khajohn Tiranathanagul, Kearkiat Praditpornsilpa, Somchai Eiam-Ong, Kriang Tungsanga, John A. Kellum

01.12.2018 | Review | Ausgabe 1/2018 Open Access

Endocan, sepsis, pneumonia, and acute respiratory distress syndrome

Nathalie De Freitas Caires, Alexandre Gaudet, Lucie Portier, Anne Tsicopoulos, Daniel Mathieu, Philippe Lassalle

01.12.2018 | Letter | Ausgabe 1/2018 Open Access

Microcirculation in cardiogenic shock supported with extracorporeal membrane oxygenation: the need for a homogeneous population and strict evolution assessment

Santiago Montero, Juliette Chommeloux, Guillaume Franchineau, Alain Combes, Matthieu Schmidt

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Ventilator-induced lung injury is aggravated by antibiotic mediated microbiota depletion in mice

Sandra-Maria Wienhold, Mario Macrì, Geraldine Nouailles, Kristina Dietert, Corinne Gurtner, Achim D Gruber, Markus M Heimesaat, Jasmin Lienau, Fabian Schumacher, Burkhard Kleuser, Bastian Opitz, Norbert Suttorp, Martin Witzenrath, Holger C Müller-Redetzky

01.12.2018 | Viewpoint | Ausgabe 1/2018 Open Access

The global need for essential emergency and critical care

Carl Otto Schell, Martin Gerdin Wärnberg, Anna Hvarfner, Andreas Höög, Ulrika Baker, Markus Castegren, Tim Baker

01.12.2018 | Review | Ausgabe 1/2018 Open Access

Ascorbic acid, corticosteroids, and thiamine in sepsis: a review of the biologic rationale and the present state of clinical evaluation

Ari Moskowitz, Lars W. Andersen, David T. Huang, Katherine M. Berg, Anne V. Grossestreuer, Paul E. Marik, Robert L. Sherwin, Peter C. Hou, Lance B. Becker, Michael N. Cocchi, Pratik Doshi, Jonathan Gong, Ayan Sen, Michael W. Donnino

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Early therapeutic plasma exchange in septic shock: a prospective open-label nonrandomized pilot study focusing on safety, hemodynamics, vascular barrier function, and biologic markers

Hannah Knaup, Klaus Stahl, Bernhard M. W. Schmidt, Temitayo O. Idowu, Markus Busch, Olaf Wiesner, Tobias Welte, Hermann Haller, Jan T. Kielstein, Marius M. Hoeper, Sascha David

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Multicenter derivation and validation of an early warning score for acute respiratory failure or death in the hospital

Mikhail A Dziadzko, Paul J Novotny, Jeff Sloan, Ognjen Gajic, Vitaly Herasevich, Parsa Mirhaji, Yiyuan Wu, Michelle Ng Gong

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Delay in antibiotic therapy results in fatal disease outcome in murine pneumococcal pneumonia

Sarah Berger, Cengiz Goekeri, Shishir K. Gupta, Julio Vera, Kristina Dietert, Ulrike Behrendt, Jasmin Lienau, Sandra-Maria Wienhold, Achim D. Gruber, Norbert Suttorp, Martin Witzenrath, Geraldine Nouailles

01.12.2018 | Letter | Ausgabe 1/2018 Open Access

Angiotensin in ECMO patients with refractory shock

Marlies Ostermann, David W. Boldt, Michael D. Harper, George W. Lim, Kyle Gunnerson

01.12.2018 | Letter | Ausgabe 1/2018 Open Access

Optimizing micafungin dosing in critically ill patients: what about extracorporeal therapies?

Patrick M. Honore, David De Bels, Leonel Barreto Gutierrez, Sebastien Redant, Rachid Attou, Andrea Gallerani, Herbert D. Spapen

01.12.2018 | Letter | Ausgabe 1/2018 Open Access

Clinical benefit of high-volume hemofiltration in severe burn injury: is it removing bad humors or actually avoiding hypervolemia?

Patrick M. Honore, David De Bels, Thierry Preseau, Sebastien Redant, Rachid Attou, Andrea Gallerani, Herbert D. Spapen

01.12.2018 | Editorial | Ausgabe 1/2018 Open Access

Is access to intensive care equitable?

Claudio M Martin

01.12.2018 | Editorial | Ausgabe 1/2018 Open Access

Ultrasound-guided vessel puncture: calling for Pythagoras’ help

Gaël Piton, Gilles Capellier, Hadrien Winiszewski

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Cost-effectiveness of procalcitonin testing to guide antibiotic treatment duration in critically ill patients: results from a randomised controlled multicentre trial in the Netherlands

Michelle M. A. Kip, Jos A. van Oers, Arezoo Shajiei, Albertus Beishuizen, A. M. Sofie Berghuis, Armand R. Girbes, Evelien de Jong, Dylan W. de Lange, Maarten W. N. Nijsten, Maarten J. IJzerman, Hendrik Koffijberg, Ron Kusters

01.12.2018 | Letter | Ausgabe 1/2018 Open Access

A brief comment on the predictive value of myeloperoxidase-conjugated DNA level in patients with septic shock

Xu Li, Xiaochun Ma

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Bright environmental light improves the sleepiness of nightshift ICU nurses

John E. Griepentrog, Hanna E. Labiner, Scott R. Gunn, Matthew R. Rosengart

01.12.2018 | Editorial | Ausgabe 1/2018 Open Access

Selective decontamination of the digestive tract in critical care: a teenage angst or coming of age issue?

Brian H. Cuthbertson

01.12.2018 | Letter | Ausgabe 1/2018 Open Access

Comparison between surgical and percutaneous tracheostomy effects on procalcitonin kinetics in critically ill patients

Maria Vargas, Pasquale Buonanno, Lina Giorgiano, Giovanna Sorriento, Carmine Iacovazzo, Giuseppe Servillo

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Is goal-directed fluid therapy based on dynamic variables alone sufficient to improve clinical outcomes among patients undergoing surgery? A meta-analysis

Qi-Wen Deng, Wen-Cheng Tan, Bing-Cheng Zhao, Shi-Hong Wen, Jian-Tong Shen, Miao Xu

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Systematic review of incretin therapy during peri-operative and intensive care

Abraham H Hulst, Mark P Plummer, Markus W Hollmann, J Hans DeVries, Benedikt Preckel, Adam M Deane, Jeroen Hermanides

01.12.2018 | Letter | Ausgabe 1/2018 Open Access

“Think. Check. Submit.” to avoid predatory publishing

Andrea Cortegiani, Steven L. Shafer

01.12.2018 | Review | Ausgabe 1/2018 Open Access

Aerosolized antibiotics for ventilator-associated pneumonia: a pairwise and Bayesian network meta-analysis

Feng Xu, Lu-Lu He, Luan-Qing Che, Wen Li, Song-Min Ying, Zhi-Hua Chen, Hua-Hao Shen

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Mechanical ventilation enhances extrapulmonary sepsis-induced lung injury: role of WISP1–αvβ5 integrin pathway in TLR4-mediated inflammation and injury

Xibing Ding, Yao Tong, Shuqing Jin, Zhixia Chen, Tunliang Li, Timothy R. Billiar, Bruce R. Pitt, Quan Li, Li-Ming Zhang

01.12.2018 | Editorial | Ausgabe 1/2018 Open Access

Treatment of central line-associated bloodstream infections

Jérémy Guenezan, Bertrand Drugeon, Nicolas Marjanovic, Olivier Mimoz

01.12.2018 | Letter | Ausgabe 1/2018 Open Access

Prediction of acute kidney injury in intensive care unit patients

Rui-Juan Guo, Fu-Shan Xue, Liu-Jia-Zi Shao

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Derivation and validation of plasma endostatin for predicting renal recovery from acute kidney injury: a prospective validation study

Hui-Miao Jia, Yue Zheng, Li-Feng Huang, Xin Xin, Wen-Liang Ma, Yi-Jia Jiang, Xi Zheng, Shu-Yan Guo, Wen-Xiong Li

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Brain death and postmortem organ donation: report of a questionnaire from the CENTER-TBI study

Ernest van Veen, Mathieu van der Jagt, Maryse C. Cnossen, Andrew I. R. Maas, Inez D. de Beaufort, David K. Menon, Giuseppe Citerio, Nino Stocchetti, Wim J. R. Rietdijk, Jeroen T. J. M. van Dijck, Erwin J. O. Kompanje, CENTER-TBI investigators and participants

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Clinical course, treatment and outcome of Pneumocystis pneumonia in immunocompromised adults: a retrospective analysis over 17 years

Julius J. Schmidt, Catherina Lueck, Stefan Ziesing, Matthias Stoll, Hermann Haller, Jens Gottlieb, Matthias Eder, Tobias Welte, Marius M. Hoeper, André Scherag, Sascha David

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Microcirculatory perfusion disturbances in septic shock: results from the ProCESS trial

Michael J. Massey, Peter C. Hou, Michael Filbin, Henry Wang, Long Ngo, David T. Huang, William C. Aird, Victor Novack, Stephen Trzeciak, Donald M. Yealy, John A. Kellum, Derek C. Angus, Nathan I. Shapiro, for the ProCESS investigators

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Validation of the SOS-PD scale for assessment of pediatric delirium: a multicenter study

Erwin Ista, Babette van Beusekom, Joost van Rosmalen, Martin C. J. Kneyber, Joris Lemson, Arno Brouwers, Gwen C. Dieleman, Bram Dierckx, Matthijs de Hoog, Dick Tibboel, Monique van Dijk

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Anxiety, Depression and Post Traumatic Stress Disorder after critical illness: a UK-wide prospective cohort study

Robert Hatch, Duncan Young, Vicki Barber, John Griffiths, David A. Harrison, Peter Watkinson

01.12.2018 | Letter | Ausgabe 1/2018 Open Access

Letter on “Pre-hospital transthoracic echocardiography for early identification of non-ST-elevation myocardial infarction in patients with acute coronary syndrome”

Guido Tavazzi, Aleksandar N Neskovic, Bogdan A Popescu, Gabriele Via

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Identification of a transcriptome profile associated with improvement of organ function in septic shock patients after early supportive therapy

Matteo Barcella, Bernardo Bollen Pinto, Daniele Braga, Francesca D’Avila, Federico Tagliaferri, Marie-Angelique Cazalis, Guillaume Monneret, Antoine Herpain, Karim Bendjelid, Cristina Barlassina

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Risk of sepsis in patients with primary aldosteronism

Chieh-Kai Chan, Ya-Hui Hu, Likwang Chen, Chin-Chen Chang, Yu-Feng Lin, Tai-Shuan Lai, Kuo-How Huang, Yen-Hung Lin, Vin-Cent Wu, Kwan-Dun Wu, TAIPAI Study Group

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Iron deficiency diagnosed using hepcidin on critical care discharge is an independent risk factor for death and poor quality of life at one year: an observational prospective study on 1161 patients

Sigismond Lasocki, Thibaud Lefebvre, Claire Mayeur, Hervé Puy, Alexandre Mebazaa, Etienne Gayat, on behalf of the FROG-ICU study group

01.12.2018 | Editorial | Ausgabe 1/2018 Open Access

How to improve worldwide early enteral nutrition performance in intensive care units?

Arthur Raymond Hubert van Zanten

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Impact of timing of continuous intravenous anesthetic drug treatment on outcome in refractory status epilepticus

Dominik Madžar, Caroline Reindl, Antje Giede-Jeppe, Tobias Bobinger, Maximilian I. Sprügel, Ruben U. Knappe, Hajo M. Hamer, Hagen B. Huttner

01.12.2018 | Research | Ausgabe 1/2018 Open Access

The combination of procalcitonin and C-reactive protein or presepsin alone improves the accuracy of diagnosis of neonatal sepsis: a meta-analysis and systematic review

Lin Ruan, Guan-Yu Chen, Zhen Liu, Yun Zhao, Guang-Yu Xu, Shu-Fang Li, Chun-Ni Li, Lin-Shan Chen, Zheng Tao

01.12.2018 | Research | Ausgabe 1/2018 Open Access

An intervention to control an ICU outbreak of carbapenem-resistant Acinetobacter baumannii: long-term impact for the ICU and hospital

Eli Ben-Chetrit, Yonit Wiener-Well, Emil Lesho, Puah Kopuit, Chaya Broyer, Liora Bier, Marc V. Assous, Shmuel Benenson, Matan J. Cohen, Patrick T. McGann, Erik Snesrud, Phillip D. Levin

01.12.2018 | Editorial | Ausgabe 1/2018 Open Access

When and how to use predictive biomarkers for corticosteroid treatment of septic shock

James A. Russell

01.12.2018 | Letter | Ausgabe 1/2018 Open Access

Adjuvant Vitamin C in critically ill patients undergoing renal replacement therapy: What’s the right dose?

Paul E Marik, Michael H Hooper

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Minimally invasive drainage in critically ill patients with severe necrotizing pancreatitis is associated with better outcomes: an observational study

Lucie Darrivere, Nathanael Lapidus, Nikias Colignon, Najim Chafai, Ulriikka Chaput, Franck Verdonk, François Paye, Thomas Lescot

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Characteristics, management, and in-hospital mortality among patients with severe sepsis in intensive care units in Japan: the FORECAST study

Toshikazu Abe, Hiroshi Ogura, Atsushi Shiraishi, Shigeki Kushimoto, Daizoh Saitoh, Seitaro Fujishima, Toshihiko Mayumi, Yasukazu Shiino, Taka-aki Nakada, Takehiko Tarui, Toru Hifumi, Yasuhiro Otomo, Kohji Okamoto, Yutaka Umemura, Joji Kotani, Yuichiro Sakamoto, Junichi Sasaki, Shin-ichiro Shiraishi, Kiyotsugu Takuma, Ryosuke Tsuruta, Akiyoshi Hagiwara, Kazuma Yamakawa, Tomohiko Masuno, Naoshi Takeyama, Norio Yamashita, Hiroto Ikeda, Masashi Ueyama, Satoshi Fujimi, Satoshi Gando, on behalf of JAAM FORECAST group

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Prognostic value of computed tomography score in patients after extracorporeal cardiopulmonary resuscitation

Jeong-Am Ryu, Young Hwan Lee, Chi Ryang Chung, Yang Hyun Cho, Kiick Sung, Kyeongman Jeon, Gee Young Suh, Taek Kyu Park, Joo Myung Lee, Minjung Kathy Chae, Jeong-Ho Hong, Sei Hee Lee, Hyoung Soo Kim, Jeong Hoon Yang

01.12.2018 | Editorial | Ausgabe 1/2018 Open Access

The paramount parameter: arterial oxygen tension versus arterial oxygen saturation as target in trials on oxygenation in intensive care

Olav Lilleholt Schjørring, Bodil Steen Rasmussen

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Performance comparison of ventricular and arterial dP/dtmax for assessing left ventricular systolic function during different experimental loading and contractile conditions

Manuel Ignacio Monge Garcia, Zhongping Jian, Jos J. Settels, Charles Hunley, Maurizio Cecconi, Feras Hatib, Michael R. Pinsky

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Influence of neutropenia on mortality of critically ill cancer patients: results of a meta-analysis on individual data

Quentin Georges, Elie Azoulay, Djamel Mokart, Marcio Soares, Kyeongman Jeon, Sandra Oeyen, Chin Kook Rhee, Pascale Gruber, Marlies Ostermann, Quentin A. Hill, Pieter Depuydt, Christelle Ferra, Anne-Claire Toffart, Peter Schellongowski, Alice Müller, Virginie Lemiale, Fabien Tinquaut, Aurélie Bourmaud, Michaël Darmon

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Impaired cerebral autoregulation is associated with brain dysfunction in patients with sepsis

Ilaria Alice Crippa, Carles Subirà, Jean-Louis Vincent, Rafael Fernandez Fernandez, Silvia Cano Hernandez, Federica Zama Cavicchi, Jacques Creteur, Fabio Silvio Taccone

01.12.2018 | Letter | Ausgabe 1/2018 Open Access

Effect of plasma exchange in acute respiratory failure due to Anti-neutrophil cytoplasmic antibody-associated vasculitis

Guillaume Geri, Benjamin Terrier, Farhad Heshmati, Hanafi Moussaoui, Julien Massot, Jean-Paul Mira, Luc Mouthon, Frédéric Pène

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Epidemiology of mechanically ventilated patients treated in ICU and non-ICU settings in Japan: a retrospective database study

Yoshiaki Iwashita, Kazuto Yamashita, Hiroshi Ikai, Masamitsu Sanui, Hiroshi Imai, Yuichi Imanaka

01.12.2018 | Letter | Ausgabe 1/2018 Open Access

Response to Gunst and Casaer on the letter to the editor “Is the protein intake saturated at doses recommended by the feeding guidelines for critically ill patients?”

Arthur Raymond Hubert van Zanten, on behalf of the study group

01.12.2018 | Letter | Ausgabe 1/2018 Open Access

Impact of Rothman index on delay of ICU transfer for hematology and oncology patients deteriorating in wards

Neal Fitzpatrick, Daniel Guck, Andry Van de Louw

01.12.2018 | Letter | Ausgabe 1/2018 Open Access

Intravenous zanamivir for influenza myocarditis and enteral malabsorption

Fritz-Patrick Jahns, Nawfel Ben-Hamouda, Matthias Kirsch, Aurélien Roumy, Lucas Liaudet

01.12.2018 | Editorial | Ausgabe 1/2018 Open Access

Didn’t inhale? Time to reconsider aerosolized antibiotics in the treatment of ventilator-associated pneumonia

Daniel A. Sweeney, Andre C. Kalil

01.12.2018 | Letter | Ausgabe 1/2018 Open Access

Is KingVision videolaryngoscope with a bougie really an effective solution for emergency intubation?

Fu-Shan Xue, Rui-Juan Guoa, Liu-Jia-Zi Shao

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Comparison of complaints to the intensive care units and those to the general wards: an analysis using the Healthcare Complaint Analysis Tool in an academic medical center in Taiwan

Jih-Shuin Jerng, Szu-Fen Huang, Hsin-Yu Yu, Yi-Chun Chan, Huang-Ju Liang, Huey-Wen Liang, Jui-Sheng Sun

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Evidence for a protective role for the rs805305 single nucleotide polymorphism of dimethylarginine dimethylaminohydrolase 2 (DDAH2) in septic shock through the regulation of DDAH activity

Simon Lambden, James Tomlinson, Sophie Piper, Anthony C. Gordon, James Leiper

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Antimicrobial exposure and the risk of delirium in critically ill patients

Jessica J. Grahl, Joanna L. Stollings, Shayan Rakhit, Anna K. Person, Li Wang, Jennifer L. Thompson, Pratik P. Pandharipande, E. Wesley Ely, Mayur B. Patel

01.12.2018 | Letter | Ausgabe 1/2018 Open Access

Gram stain-guided antibiotic choice: a GRACEful method to safely restrict overuse of broad-spectrum antibiotic agents

Jumpei Yoshimura, Kazuma Yamakawa, Takahiro Kinoshita, Satoshi Fujimi

01.12.2018 | Letter | Ausgabe 1/2018 Open Access

Comparison of diagnostic accuracy among procalcitonin, C-reactive protein, and interleukin 6 for blood culture positivity in general ICU patients

Qin Wu, Hao Yang, Yan Kang

01.12.2018 | Letter | Ausgabe 1/2018 Open Access

Patients’ primary activities prior to critical illness: how well do clinicians know them and how likely are patients to return to them?

Alexi T. Gosset, Michael C. Sklar, Aaron M. Delman, Michael E. Detsky

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Tigecycline in critically ill patients on continuous renal replacement therapy: a population pharmacokinetic study

A. Broeker, S. G. Wicha, C. Dorn, A. Kratzer, M. Schleibinger, F. Kees, A. Heininger, M. G. Kees, H. Häberle

01.12.2018 | Research | Ausgabe 1/2018 Open Access

What is the diagnostic accuracy of single nerve conduction studies and muscle ultrasound to identify critical illness polyneuromyopathy: a prospective cohort study

Daniel A. Kelmenson, Dianna Quan, Marc Moss

01.12.2018 | Review | Ausgabe 1/2018 Open Access

Inhaled amikacin for severe Gram-negative pulmonary infections in the intensive care unit: current status and future prospects

Antoni Torres, Anna Motos, Denise Battaglini, Gianluigi Li Bassi

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Prevalence and risk factors for acute kidney injury among trauma patients: a multicenter cohort study

Anatole Harrois, Benjamin Soyer, Tobias Gauss, Sophie Hamada, Mathieu Raux, Jacques Duranteau, for the Traumabase® Group

01.12.2018 | Editorial | Ausgabe 1/2018 Open Access

Intra-aortic balloon pump: is the tide turning?

Sandro Gelsomino, Daniel M. Johnson, Roberto Lorusso

01.12.2018 | Letter | Ausgabe 1/2018 Open Access

Response to “Categorization of post-cardiac arrest patients according to the pattern of amplitude-integrated electroencephalography after return of spontaneous circulation”

Jia Li, Ning-Tao Li, Yong-Gang Peng

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Identification of subclasses of sepsis that showed different clinical outcomes and responses to amount of fluid resuscitation: a latent profile analysis

Zhongheng Zhang, Gensheng Zhang, Hemant Goyal, Lei Mo, Yucai Hong

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Effect of cytomegalovirus reactivation on the time course of systemic host response biomarkers in previously immunocompetent critically ill patients with sepsis: a matched cohort study

Kirsten van de Groep, Stefan Nierkens, Olaf L. Cremer, Linda M. Peelen, Peter M. C. Klein Klouwenberg, Marcus J. Schultz, C. Erik Hack, Tom van der Poll, Marc J. M. Bonten, David S. Y. Ong, on behalf of the MARS consortium

01.12.2018 | Letter | Ausgabe 1/2018 Open Access

Response to: A brief comment on the predictive value of myeloperoxidase-conjugated DNA level in patients with septic shock

Naoshi Takeyama

01.12.2018 | Letter | Ausgabe 1/2018 Open Access

Response to “Adjuvant vitamin C in cardiac arrest patients undergoing renal replacement therapy: an appeal for a higher high-dose”

Angelique M. E. Spoelstra – de Man, Harm-Jan de Grooth, Paul W. G. Elbers, Heleen M. Oudemans – van Straaten

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Estimating severity of influenza epidemics from severe acute respiratory infections (SARI) in intensive care units

Liselotte van Asten, Angie Luna Pinzon, Dylan W. de Lange, Evert de Jonge, Frederika Dijkstra, Sierk Marbus, Gé A. Donker, Wim van der Hoek, Nicolette F. de Keizer

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Mild decrease in heart rate during early phase of targeted temperature management following tachycardia on admission is associated with unfavorable neurological outcomes after severe traumatic brain injury: a post hoc analysis of a multicenter randomized controlled trial

Akihiko Inoue, Toru Hifumi, Yasuhiro Kuroda, Naoki Nishimoto, Kenya Kawakita, Susumu Yamashita, Yasutaka Oda, Kenji Dohi, Hitoshi Kobata, Eiichi Suehiro, Tsuyoshi Maekawa, on behalf of the Brain Hypothermia (B-HYPO) Study Group in Japan

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Intrapulmonary autologous transplant of bone marrow-derived mesenchymal stromal cells improves lipopolysaccharide-induced acute respiratory distress syndrome in rabbit

Mohammad Reza Mokhber Dezfouli, Massoumeh Jabbari Fakhr, Sirous Sadeghian Chaleshtori, Mohammad Mehdi Dehghan, Alireza Vajhi, Roshanak Mokhtari

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Circulating adrenomedullin estimates survival and reversibility of organ failure in sepsis: the prospective observational multinational Adrenomedullin and Outcome in Sepsis and Septic Shock-1 (AdrenOSS-1) study

Alexandre Mebazaa, Christopher Geven, Alexa Hollinger, Xavier Wittebole, Benjamin Glen Chousterman, Alice Blet, Etienne Gayat, Oliver Hartmann, Paul Scigalla, Joachim Struck, Andreas Bergmann, Massimo Antonelli, Albertus Beishuizen, Jean-Michel Constantin, Charles Damoisel, Nicolas Deye, Salvatore Di Somma, Thierry Dugernier, Bruno François, Stephane Gaudry, Vincent Huberlant, Jean-Baptiste Lascarrou, Gernot Marx, Emmanuelle Mercier, Haikel Oueslati, Peter Pickkers, Romain Sonneville, Matthieu Legrand, Pierre-François Laterre, AdrenOSS-1 study investigators

01.12.2018 | Letter | Ausgabe 1/2018 Open Access

The pharmacokinetic challenge of treating invasive aspergillosis complicating severe influenzae assisted by extracorporeal membrane oxygenation

Hadrien Winiszewski, Anne-Claire Rougny, Jennifer Lagoutte-Renosi, Laurence Millon, Gilles Capellier, Jean-Christophe Navellou, Gael Piton, Anne-Laure Clairet

01.12.2018 | Letter | Ausgabe 1/2018 Open Access

Trigonometry in daily ultrasound practice

Alessandro De Cassai, Ludovica Sandei, Michele Carron

01.12.2018 | Editorial | Ausgabe 1/2018 Open Access

Blood purification in sepsis

Achim Jörres

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Neutrophil extracellular traps (NETs) are increased in the alveolar spaces of patients with ventilator-associated pneumonia

Carmen Mikacenic, Richard Moore, Victoria Dmyterko, T. Eoin West, William A. Altemeier, W. Conrad Liles, Christian Lood

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Kidney histopathology in lethal human sepsis

Adnan Aslan, Marius C. van den Heuvel, Coen A. Stegeman, Eliane R. Popa, Annemarie M. Leliveld, Grietje Molema, Jan G. Zijlstra, Jill Moser, Matijs van Meurs

01.12.2018 | Research | Ausgabe 1/2018 Open Access

Plasma mitochondrial DNA and metabolomic alterations in severe critical illness

Pär I. Johansson, Kiichi Nakahira, Angela J. Rogers, Michael J. McGeachie, Rebecca M. Baron, Laura E. Fredenburgh, John Harrington, Augustine M. K. Choi, Kenneth B. Christopher

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